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http://dx.doi.org/10.22156/CS4SMB.2022.12.03.126

Anti-Obesity Effects of Red Onions Extract  

Song, Hwan (Division of Beauty Design, Chodang University)
Seo, Ji-Hun (Jisung Food Company Limited)
Publication Information
Journal of Convergence for Information Technology / v.12, no.3, 2022 , pp. 126-131 More about this Journal
Abstract
Obesity is known as a metabolic disease caused by abnormal differentiation of fat tissue due to an imbalance between energy intake and consumption.. The purpose of this study was to confirm the changes in the genes associated with pancreatic lipase activity and pre-adipocyte cell differentiation by treatment of red onion extract treatment. The effect of red onion extract treatment on pre-adipocyte differentiation was evaluated using 3T3-L1 adipocytes, and the activity of related genes was confirmed through Real-Time PCR. As a result of the experiment, the red onion extract inhibit pancreatic lipidase activity by concentration dependent manner. In addition, it was found to inhibit adipocyte differentiation and inhibit the activity of genes(C/EBP-α, C/EBP-β, PPAR-γ) associated with adipocyte differentiation. Through the results of this experiment, it is suggested that the red onion extract can be developed as a high potential material with anti-obesity efficacy by suppressing adipocytic differentiation by controlling genes related to adipocyte differentiation.
Keywords
Red onion extract; Anti-obesity; Pre-adipocyte; Lipase inhibition; Adipocytic differentiation;
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Times Cited By KSCI : 4  (Citation Analysis)
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