• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.37 no.2
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• pp.166-174
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• 2009

The liquid column trajectory and column breakup length characteristics have been experimentally studied in angled jets injected into subsonic crossflow. Pulsed shadowgraph photography and Planar Liquid Laser Induced Fluorescence measurements were used to determine the angled effects. And the main objectives of this research are to get a empirical formula of liquid column trajectory and breakup length with below the $90^{\circ}$ degree injection angle conditions, and were compared with previous results. It was also found that the empirical formula, which reversed injection conditions of air stream. As the result, This has been shown that liquid column trajectories and column breakup length were spatially dependent on various injection angle, normalized injector exit diameter, air-stream and fuel injection velocity. Furthermore, the empirical formula of liquid column trajectories and breakup length has been some different of drag coefficient results between normal angled injection and reversed injection in subsonic crossflow.

• Journal of The Korean Association For Science Education
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• v.31 no.5
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• pp.680-693
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• 2011

In conceptual ecology, a concept does not exist independently but occupies an ecological niche in ecological environment. Among many biological concepts, genetic concepts are connected to several units including the genetics unit, and within the genetics unit the concepts of sub-areas are highly dependent on one another. For this reason, we analyzed conceptual diversity and conceptual proximity of genetic concepts through the ecological niche approach. For this purpose, we surveyed 995 9th graders. The areas covered in the survey were four genetic concepts: gene, chromosome, mitosis, and meiosis. The questionnaire presented biological concepts or terms related to each area, and the respondent marked the relevance between the presented biological concepts or terms and each area on a scale of 1~30 points. With 9th grade students, we analyzed the change of genetic concepts through class by the ecological niche approach. Through class, the total number of concepts increased in all of the areas, and the increase was smallest in the area of meiosis followed by mitosis, chromosome and gene. Relative density decreased with increases in the number of concepts. The conceptual diversity index also increased through class in all of the areas, and the increase was smallest in the area of meiosis followed by mitosis, chromosome and gene. In addition, difference in the relative density of concepts was reduced after class, and difference in the score of relevance was also reduced and consequently similarity among concepts increased. From these results were drawn conclusions as follows: First, through class, the conceptual diversity of genetic concepts increased. Second, through class, the conceptual proximity of genetic concepts increased.

• Journal of the Korean Society of Propulsion Engineers
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• v.25 no.5
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• pp.10-17
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• 2021

In this study, cold-flow test of simulant gel is conducted using a pressure swirl injector to identify spray characteristics according to gellant weight percent. Experiment results show the aircore is developed locally at the nozzle and expanded to the entire swirl chamber as the supply pressure increases. The aircore formation of simulant gel showed no significant difference compared to Newtonian fluid. The spray pattern was classified into four distinct shapes where relationship between the breakup regimes and dimensionless numbers were investigated. In the future, additional study is necessary to understand the aircore formation mechanism, stability and spray characteristics at different configuration of the swirl chamber shape.

• Korean Journal of Biological Psychiatry
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• v.15 no.2
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• pp.83-91
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• 2008

Objectives : Neurological soft signs have been regarded as endophenotypes associated with the genetic basis of schizophrenia. This study was to investigate the intra-familial correlations of the neurological soft signs according to their genetic loading. Methods : Schizophrenic patients(N=14) were included, who had one parent with a family history of schizophrenia and the other without it. Genetic loading was determined by the patient's family history of schizophrenia using the Family Interview for Genetic Studies(FIGS). These parents were subdivided into two groups. The first group was designated as 'presumed carriers'(N=9) of genetic loading, who had one or more schizophreic firstor second-degree relatives. The second group was designated as 'presumed non-carriers'(N=11) of genetic loading, who had no schizophrenic first- or second-degree relatives. Normal controls(N=12) consisted of people without schizophrenic relatives. NSS were evaluated using the Neurological Evaluation Scale-Korean Version (NES-K), and the intra-familial correlations of NSS were tested using the Intra-Class Coefficients(ICC) method. Results : The scores of Motor Coordination subdimension of NES-K were significantly correlated between the patients and their presumed carriers(ICC=.804, p=.016), but not significantly correlated between the patients and their presumed noncarriers. In other subdimensions of NES-K, no significant correlation were found between the patients and their parents regardless of the genetic loading. But, there were no statistically significant differences in the scores of Motor Coordination subdimension of NES-K between the patients and controls. Conclusion : This study did not prove that the neurological soft signs might be an endophenotype of schizophrenia that cosegregate with the genetic loading. The future study using more subjects than this would be needed.

• Sleep Medicine and Psychophysiology
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• v.11 no.1
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• pp.44-49
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• 2004

Objectives: The purpose of this study was to investigate whether longitudinal changes in positive and negative symptoms affect cognitive functioning in chronic schizophrenia. Methods: Sixty-eight patients diagnosed with DSM-IV schizophrenia were examined on two occasions over 6 months for symptoms and cognitive changes. Symptoms were measured by PANSS. Cognitive functions were examined for sustained attention, executive function, concentration and attention, and verbal memory and learning using Degraded Stimulus Continuous Performance Test, Wisconsin Card Sorting Test, Digit Span, and Rey Auditory Verbal Learning Test, respectively. Twenty control subjects were assessed to compare the cognitive scores of remitted schizophrenic patients. Results: Patients showed significant improvement in symptoms and all cognitive tests after 6 months treatments. Significant improvements in positive and negative symptoms did not predict improvements in any aspect of cognitive functioning measured. Normal controls performed significantly better than remitted schizophrenic patients on all cognitive tests. The results show no relationship between change in symptoms and change in cognition in chronic schizophrenia. Conclusion: We suggest that symptomatic and cognitive impairment may be a distinct construct. These findings highlight the importance of treating cognitive impairment in addition to the clinical symptoms of schizophrenia.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 1998.04a
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• pp.27-27
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• 1998

연구소기내에서 원활한 연소를 위하여 액체의 균일하고 완전한 미소분열 문제는 매우 중요한 연구분야라 할 수 있으며, 특히 항공기용 가스터빈 연소기에 사용되는 분사 시스템의 설계시에는 단순한 미소분열 문제뿐 아니라 시동성 향상, 화염의 안정화, 공해물질의 저감 등은 물론 압력 차가 작고 유량범위가 넓으며 공기를 이용한 미립화(Atomization)의 효율이 낮은 영역, 즉, 시동(Start-up) 및 플레임 아웃(Flame-out)근처의 영역에서도 효율적인 미립화가 이루어지도록 고려되어져야 한다.

• Journal of Life Science
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• v.27 no.6
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• pp.623-631
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• 2017

In the subventricular zone (SVZ) and the subgranular zone of the brain, neurogenesis occurs throughout one's lifespan. Neural stem cells (NSCs) in these regions divide to maintain their stem cell pools as well as differentiate into neurons and glial cells. To monitor cell division, a thymidine analogue such as 5-ethynyl-2'-deoxyuridine (EdU) has been used. In some cases, EdU was applied to label newly born neurons. Here, we report about the effects of EdU on the proliferation and differentiation of NSCs cultured from mouse SVZ. First, when NSCs were cultured in a proliferation medium containing EdU for 24 hr, they did not generate any neurons under the following differentiation conditions. When EdU was applied to the proliferating NSCs for 1 hr prior to differentiation, neurogenesis was still substantially reduced. Second, EdU decreased cell proliferation of NSCs in dose- and time-dependent manners. Finally, EdU inhibited differentiation into oligodendrocyte lineage, while the number of glial fibrillary acidic protein (GFAP)-positive astrocytes increased. To our knowledge, these findings are the first to show the effects of EdU on the differentiation of SVZ NSCs and suggest that cell division is necessary for differentiation into neurons and oligodendrocytes.

• Journal of the Korean Institute of Telematics and Electronics S
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• v.35S no.8
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• pp.68-76
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• 1998

In this paper, a new morphological image segmentation algorithm of hierarchical structure by binary split is proposed. It splits a region with the lowest quality into two regions using only two markers having the highest contrast. Therefore, it improves the quality of image with limited regions and reduces contour information which is not sensitive to human visual system, when compared with the conventional algorithm. It is appropriate to PSTN, LAN, and mobile networks, of which the available transmission bandwidth is very limited, because the number of regions can be controlled. And the proposed algorithm shows very simple structure because it doesn't need post processing to eliminate small regions and reduces much computation by using only structuring element of small size at simplification step of each hierarchical structure when compared with the conventional algorithm.

• Korean Journal of Microbiology
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• v.54 no.4
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• pp.325-329
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• 2018

Thp1/PCID2, PCI domain-containing protein, is a component of the evolutionally conserved TREX-2 complex linking mRNA transcription and export. In fission yeast, Schizosaccharomyces pombe, the pci2 (SPBC1105.07c) gene encodes a PCI domain-containing protein that is predicted as a fission yeast orthologue of Thp1 (in budding yeast)/PCID2 (in human). Repression of pci2 expression inhibited both growth and mRNA export. And over-expression of pci2 also exhibited growth retardation with slight accumulation of $poly(A)^+$ RNA in the nucleus. Moreover, yeast two-hybrid and co-immunoprecipitation analysis showed that the Pci2 protein physically interacted with Sac3 and Dss1, which are members of TREX-2 complex. These observations support that the S. pombe Pci2 protein, as a component of TREX-2 complex, is implicated in mRNA export.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.47 no.3
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• pp.204-211
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• 2019

The analysis on two-phase flow in a Lean Direct Injection(LDI) combustor has been investigated. Linearized Instability Sheet Atomization(LISA) and Aerodynamically Progressed Taylor Analogy Breakup(APTAB) breakup models are applied to simulate the droplet breakup process in hollow-cone spray. Breakup model is validated by comparing penetration length and Sauter Mean Diameter(SMD) of the experiment and simulation. In the LDI combustor, Precessing Vortex Core(PVC) is developed by swirling flow and most droplets are atomized along the PVC. It has been confirmed that all droplets have Stokes number less than 1.0.