• The Journal of Korean Obstetrics and Gynecology
• /
• 제28권4호
• /
• pp.31-45
• /
• 2015

Objectives : The purpose of this study is to examine the relationship between the symptoms of primary dysmenorrhea and pulse energy of Chon, Gwan and Cheok. Methods The subjects of this study who had certain range of dysmenorrhea symptom. The degree of dysmenorrhea were assessed by Visual Analog Scale (VAS), Multidimensional Verbal Rating Scale (MVRS), Cox Menstrual Symptom Scale (CMSS) and measured by 3D Blood Pressure Pulse Analyzer(3D-MAC) tests at menstruation start date. Data analysis included descriptive statistics and multiple linear regression using the SPSS/WIN 18.0 program. Results : The induced results are as follows;The induced results are as follows 1. There were no significant relationship between the pulse energy and the sum values of VAS, MVRS and checking part of severity of CMSS. 2. The frequency domain of CMSS were significantly associated with pulse energy. 3. In linear regression models, the model of Left Chon had the especially highest value of explanatory power. (R ² = 0.517) Conclusions : The pulse energy changes are related to the symptoms of primary dysmenorrhea.

• The Journal of Korean Obstetrics and Gynecology
• /
• 제28권4호
• /
• pp.21-30
• /
• 2015

Objectives : The purpose of this study was to analyze the characteristics of the pulse energy in women who complained mild hyperemesis gravidarum. Methods : We analyzed the values of pulse energy on 14 patients who suffered mild hyperemesis gravidarum. The patients’ symptoms were assessed by PUQE (Pregnancy-Unique Quantification of Emesis scale). Statistical analysis was performed using SPSS 18.0 for window program, one way ANOVA, pearson correlation coefficient. Results : The results were as follows. 1. There were no statistically significant pulse energy differences. 2. The Chon pulse energy showed negative correlations with each Kwan and Cheok. 3. PUQE score showed positive correlations with right Chon pulse energy and negative correlations with right Kwan pulse energy. Conclusions : The result suggested that PUQE score changes be positive related with spleen pulse energy and negative related with lung pulse energy.

• The Journal of Korean Obstetrics and Gynecology
• /
• 제31권3호
• /
• pp.121-130
• /
• 2018

Objectives: The purpose of this study is to report the effects of Korean medical treatment in ovarian disorder patients resistant to controlled ovarian hyperstimulation. There are some case-reports about effectiveness of the Korean medical treatment to treat ovulation disorder and become pregnant, but cases are still deficient. Methods: The patient was diagnosed possibility of premature ovarian failure by serum hormone assay and underwent hyperstimulation to freeze oocyte. But ovary had no response to hyperstimulation. She was treated by Korean medical treatment, such as herbal medicine, acupuncture and moxibustion. Results: After the treatment, the patient recovered from irregular ovulation & menstrual cycle and became pregnant and gave birth. Conclusions: This case shows the Korean medical treatment might be effective in ovarian disorder patients resistant to hyperstimulation.

• The Journal of Korean Obstetrics and Gynecology
• /
• 제31권3호
• /
• pp.131-140
• /
• 2018

Objectives: The posthysterectomy syndrome is sequela which occurred after hysterectomy. Even though hysterectomy is one of common surgery in gynecologic operation, the complications of surgery easily occurred. The purpose of this study is to report the effect of traditional Korean medicine on posthysterectomy syndrome, especially anemia. Methods: The patient having treated with hospital management, from January 19th in 2018 until Feburary 8th in 2018, participated. Her chief complaint was dizziness which occurred after hysterectomy. We diagnosed her as anemia based on symptoms and blood test result. We treated the patient with herbal medicine, moxibustion and iron pills. The efficacy of treatment was evaluated with visual analogue scale (VAS) and complete blood cell count. Results: During hospitalization period, the symptoms including dizziness, fatigue, headache, neck pain, abdominal pain were reduced. After discharging, we identified that the level of hemoglobin was normalized. Conclusions: To recover from posthysterectomy syndrome, Korean medicine treatment is considered to be effective.

• The Journal of Korean Obstetrics and Gynecology
• /
• 제31권3호
• /
• pp.20-32
• /
• 2018

Objectives: The purpose of this study is to identify the effectiveness of fumigation treatment, provide a clinical basis for fumigation therapy, and develop treatment protocols through consideration of treatment methods and herbal medicines. Methods: We searched for randomized controlled clinical trials using fumigation treatment on mycotic vaginitis in 8 electronic databases such as EMBASE, Pubmed, and CNKI. The results of the studies were analyzed and the risk of bias was assessed by using Cochrane risk of bias tool. A meta-analysis was performed to reveal the effectiveness of fumigation compared to control treatments. Results: We finally selected 5 studies among 54 articles according to inclusion criteria and exclusion criteria. In all selected studies, herbal fumigation was more effective than any control treatment and all the studies were statistically significant. Conclusions: The study provides a basis for applying fumigation treatment to patients with mycotic vaginitis and helps developing a treatment protocol of caring patients of mycotic vaginitis. But the limitation of this study is that the number of studies included is small and quantitative synthesis of all results has not been achieved.

• The Journal of Korean Obstetrics and Gynecology
• /
• 제31권4호
• /
• pp.188-196
• /
• 2018

Objectives: This study is to report the clinical effectiveness of the complex Korean medicine therapy on a postoperative endometriosis patient's hypoestrogenic side effects who is treated with GnRH-agonist injection. Methods: The patient in this case was diagnosed with endometriosis and has been treated with GnRH-a injection after laparoscopic operation. The patient complained hot flash and sweating mainly after GnRH-a treatment. The patient received complex Korean medicine therapy during 10 days admission period. The clinical effects were evaluated through KI (Kupperman's Index) and SF-36 (36 item Short Form Health Survey). Results: After the complex Korean medicine therapy, the various clinical symptoms including hot flash and sweating were improved. Also, the quality of life was enhanced. Conclusions: This case report shows that the complex Korean medicine therapy was effective for treating hypoestrogenic side effects occurred after GnRH-a treatment in postoperative endometriosis patient.

• The Journal of Korean Obstetrics and Gynecology
• /
• 제31권4호
• /
• pp.110-127
• /
• 2018

Objectives: To evaluate the effectiveness and safety of traditional herbal medicine (THM) in the treatment of dysfunctional uterine bleeding (DUB) versus conventional western medicine. Methods: Randomized Controlled Trials (RCTs) comparing THM vs. conventional western medicine for DUB, were obtained from PubMed, Cochrane Library, Embase, CNKI, RISS, NDSL, KISS and OASIS. The risk of bias was assessed by using Cochrane's risk of bias tool. Results: 16 RCTs with 1,659 patients were identified and reviewed. 10 RCTs reported THM was statistically effective than control group in effective rate. Also recurrent rate was estimated in 6 RCTs and was lower than control group. 7 studies observed adverse events (AEs) and severe AEs were not reported. Conclusions: Despite several limitations, this review suggested that THM was safe and effective in the treatment of DUB. THM may also decrease the recurrence rate. However, this could not be proven conclusively. To ensure evidence-based clinical practice, more sternly designed trials are warranted.

• The Journal of Korean Obstetrics and Gynecology
• /
• 제19권1호
• /
• pp.272-285
• /
• 2006

Purpose : To report the clinical condition and the effect of oriental medicine treatment on patients with uterine myoma. Methods : Our research was based on 41 cases of uterine myoma through medical records from November, 2003 to March, 2005. Research items were age of patients at first visit, BMI, past medical history, pregnancy history, preceding operation, constitution, accompanied symptoms, results after Oriental medicine treatment, treatment period. And we analyzed statistically about factors to affect results after treatment. Results : Average age of patients was 34.8 years old. After Oriental medicine treatment, the size of myoma of 9 patients(47.4%) lessened or disappeared, the VAS pain score during periods was decreased in 17 patients(72.7%). Conclusion : The result showed that Oriental medicine treatment can be effective for the management of uterine myoma without hysterectomy.

• The Journal of Korean Obstetrics and Gynecology
• /
• 제19권1호
• /
• pp.155-165
• /
• 2006

이 연구는 MCF-7 인간 유방암 세포주에 대한 귀출파징탕(歸朮破癥湯) 추출물의 증식억제효과 세포독성효과 세포사 유발효과를 확인하기 위하여 이루어졌다. MCF-7 인간 유방암 세포주는 Dulbecco's modified Eagle's medium/F12 (DMEM/F12)에 10% fetal bovine serum(FBS;Gibco) 와 항생제를 가하여 만든 배지를 이용하여 배양하였고, MCPF-7 세포를 96- well plate에 접종한 후 다양한 농도(0~2000g/ml)의 귀출파징탕(歸朮破癥湯)이 든 배지로 처리하고 다양한 시간(48, 96, 192)동안 배양하여 현미경으로 관찰하고 각각 MTS assay kit를 이용하여 세포생존율을 측정하였다. 세포독성은 Sulforhodamine B assay 방법을 이용해 측정하였고 세포사 과정에서 MCF-7세포에서의 caspase 활성화를 측정하기 위해 Western blotting을 수행하여 poly ADP ribose polymerase(PARP)의 절단을 확인하였다. 실험결과 귀출파징탕(歸朮破癥湯) 추출물에 의한 세포성장 및 독성효과는 시간 및 농도에 비례하는 것으로 나타났고 세포고사과정에서 작용하는 caspase의 전 기질인 PARP 절단량이 귀출파징탕(歸朮破癥湯) 처리 농도와 시간에 비례하여 증가하였다. 이것은 caspase-3가 MCF-7 세포의 성장을 억제하는데 중요한 역할을 수행함을 의미한다. 따라서 귀출파징탕(歸朮破癥湯)은 다양한 기전에 의해서 유방암 세포에 대한 억제효과를 가진다는 것을 인식할 수 있다.

• The Journal of Korean Obstetrics and Gynecology
• /
• 제19권1호
• /
• pp.261-271
• /
• 2006

Purpose : Dysmenorrhea which repeat every menstrual phase give complaints like pain, vomiting, nasal bleeding and etc. But in many textbooks pathogenesis and treatment process of dysmenorrhea obscure. So the purpose of this study is to identify the conception, pathogenesis and treatment process of dysmenorrhea. Methods : After catching the limitations of preexistence theory about dysmenorrhea, I show a meaningful argument of dysmenorrhea. Results : The conception, pathogenesis and treatment process of dysmenorrhea are like this. Dysmenorrhea which occurs for menstrual phase can make deficiency of blood. There are intimate relations between uterine function and the five Zang-organs, especially heart, spleen and liver, so menstruation induces the weakness of those organs. And the insufficiency of kidney and conception-thorough vessel which have control over the uterine function can make dysmenorrhea. Conclusion : The deficiency of kidney which is responsible for holding Qi breaks down the balance of Zang-organs Yin-Yang, then dysmenorrhea appears through Zang-organs weakness of heart, spleen and liver. For the treatment of dysmenorrhea, we should consider preferentially the deficiency of kidney, afterward Bianzheng Lunzhi of the Zang-fu organs.