Browse > Article
http://dx.doi.org/10.15204/jkobgy.2018.31.4.188

Complex Korean Medicine Therapy for Hypoestrogenic Side Effects of Gonadotropin Releasing Hormone Agonist Administration to Postoperative Endometriosis Patient: A Case Report  

Park, Hye-Rin (Dept. of Korean Medicine Obstetrics & Gynecology, Chung-Yeon Korean Medicine Hospital)
Jo, Hee-Geun (Chung-Yeon Medical Institute)
Jo, Hyun-Jeong (Dept. of Korean Medicine Obstetrics & Gynecology, Chung-Yeon Korean Medicine Hospital)
Choi, Ji-Hyun (Dept. Obstetrics & Gynecology, Chosun University Hospital)
Publication Information
The Journal of Korean Obstetrics and Gynecology / v.31, no.4, 2018 , pp. 188-196 More about this Journal
Abstract
Objectives: This study is to report the clinical effectiveness of the complex Korean medicine therapy on a postoperative endometriosis patient's hypoestrogenic side effects who is treated with GnRH-agonist injection. Methods: The patient in this case was diagnosed with endometriosis and has been treated with GnRH-a injection after laparoscopic operation. The patient complained hot flash and sweating mainly after GnRH-a treatment. The patient received complex Korean medicine therapy during 10 days admission period. The clinical effects were evaluated through KI (Kupperman's Index) and SF-36 (36 item Short Form Health Survey). Results: After the complex Korean medicine therapy, the various clinical symptoms including hot flash and sweating were improved. Also, the quality of life was enhanced. Conclusions: This case report shows that the complex Korean medicine therapy was effective for treating hypoestrogenic side effects occurred after GnRH-a treatment in postoperative endometriosis patient.
Keywords
Endometriosis; Gonadotropin-Releasing Hormone; Side Effects; Kupperman's Index; Traditional Korean Medicine;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Hickey M, Ballard K, Farquhar C. Endometriosis. BMJ. 2014;348:g1752.   DOI
2 Duffy JM, et al. Laparoscopic surgery for endometriosis. Cochrane Database Syst Rev. 2014 Apr 3;(4):CD011031.
3 Tandoi I, et al. High rate of endometriosis recurrence in young women. J Pediatr Adolesc Gynecol. 2011;24(6):376-9.   DOI
4 Bozdag G. Recurrence of endometriosis: risk factors, mechanisms and biomarkers. Womens Health(Lond). 2015;11(5):693-9.
5 Brown J, Pan A, Hart RJ. Gonadotrophin -releasing hormone analogues for pain associated with endometriosis. Cochrane Database Syst Rev. 2010 Dec 8;(12):CD008475.
6 Wu D, et al. Clinical efficacy of add-back therapy in treatment of endometriosis: a meta-analysis. Arch Gynecol Obstet. 2014;290(3):513-23.   DOI
7 Bedaiwy MA, Allaire C, Alfaraj S. Long-term medical management of endometriosis with dienogest and with a gonadotropin-releasing hormone agonist and add-back hormone therapy. Fertil Steril. 2017;107(3):537-48.   DOI
8 Zhou Q, et al. Chinese herbal medicine Kuntai capsule for treatment of menopausal syndrome: a systematic review of randomized clinical trials. Complement Ther Med. 2016;29:63-71.   DOI
9 Chen JM, et al. Efficacy and safety investigation of Kuntai capsule for the add-back therapy of gonadotropin releasing hormone agonist administration to endometriosis patients: a randomized, double-blind, blank- and tibolonecontrolled study. Chin Med J(Engl). 2015;128(4):427-32.   DOI
10 Blatt MH, Wiesbader H, Kupperman HS. Vitamin E and climateric syndrome. AMA Arch Intern Med. 1953;91(6):792-9.   DOI
11 Choi JE, et al. the Clinical Analysis of the Symptoms and Characteristics on 50 Cases of Postmenopause syndromes. J Korean Obstet Gynecol. 2002;15(2):144-54.
12 Nam BH, Lee SW. Testing the Validity of the Korean SF-36 Health Survey. Journal of Health Informatics and Statistics. 2003;28(2):3-24.
13 Tsze DS, et al. Validity and Reliability of the Verbal Numerical Rating Scale for Children Aged 4 to 17 Years With Acute Pain. Ann Emerg Med. 2018;71(6):691-702.   DOI
14 Hornstein MD, et al. Prospectiverandomized double-blind trial of 3 versus 6 months of nafarelin therapy for endometriosis associated pelvic pain. Fertil Steril 1995;63(5):955-62.   DOI
15 Yang F, et al. Radix Bupleuri: A Review of Traditional Uses, Botany, Phytochemistry, Pharmacology, and Toxicology. Biomed Res Int. 2017;2017:7597596.
16 Practice Committee of the American Society for Reproductive Medicine. Treatment of pelvic pain associated with endometriosis: a committee opinion. Fertil Steril. 2014;101(4):927-35.   DOI
17 Baek SE, et al. Clinical Study for Three Cases of Hysterectomy Treated by Boheo-tang Gagambang with Acupuncture and Moxa. J Korean Obstet Gynecol. 2015;28(3):119-27.   DOI
18 Cho HJ, Kim YS, Lim EM. Effects of Astragalus membranaceuson Surgically Induced Endometriosis in Rats. J Korean Obstet Gynecol. 2007;20(2):43-59.
19 Kim SJ, et al. Antidepressant-like effects of lycii radicis cortex and betaine in the forced swimming test in rats. Biomol Ther (Seoul). 2013; 21(1):79-83.   DOI
20 Kim JH, et al. The effects of Lycii Radicis Cortex on RANKL-induced osteoclast differentiation and activation in RAW 264.7 cells. Int J Mol Med. 2016;37(3):649-58.   DOI
21 Befus D, et al. Management of Menopause Symptoms with Acupuncture: An Umbrella Systematic Review and Meta-Analysis. J Altern Complement Med. 2018;24(4):314-23.   DOI
22 Qu F, Zhou J, Nan R. Acupuncture for perimenopausal symptoms in women who underwent oophorectomy a comparative study. Forsch Komplementmed. 2007; 14(1):25-32.
23 Lim EM, Kwon KR, Yuk SS. Effects of Ouhyul Herbal Acupuncture on Experimentally Induced Endometrosis in Rats. Journal of pharmacopuncture. 2006;9(1):83-94.   DOI
24 Shen J, Ai B, Shen M. Effectiveness of Mild Moxibustion for Sub-Health Conditions in Pre- and Post-Menopausal Women: A Randomized Controlled Clinical Trial. Med Sci Monit. 2018; 24:2907-11.   DOI
25 Gaubeca-Gilarranz A, et al. Effectiveness of dry needling of rectus abdominis trigger points for the treatment of primary dysmenorrhoea: a randomised parallel-group trial. Acupunct Med. 2018;36(5):302-10.   DOI
26 Kim HW, Yoo JE. Inhibitory effect of traditional Korean medicine on the recurrent endometriosis after laparoscopic excision: a case report. Integr Med Res. 2018;7(3):296-301.   DOI