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Analysis of Interactions in Multiple Genes using IFSA(Independent Feature Subspace Analysis) (IFSA 알고리즘을 이용한 유전자 상호 관계 분석)

  • Kim, Hye-Jin;Choi, Seung-Jin;Bang, Sung-Yang
    • Journal of KIISE:Computer Systems and Theory
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    • v.33 no.3
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    • pp.157-165
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    • 2006
  • The change of external/internal factors of the cell rquires specific biological functions to maintain life. Such functions encourage particular genes to jnteract/regulate each other in multiple ways. Accordingly, we applied a linear decomposition model IFSA, which derives hidden variables, called the 'expression mode' that corresponds to the functions. To interpret gene interaction/regulation, we used a cross-correlation method given an expression mode. Linear decomposition models such as principal component analysis (PCA) and independent component analysis (ICA) were shown to be useful in analyzing high dimensional DNA microarray data, compared to clustering methods. These methods assume that gene expression is controlled by a linear combination of uncorrelated/indepdendent latent variables. However these methods have some difficulty in grouping similar patterns which are slightly time-delayed or asymmetric since only exactly matched Patterns are considered. In order to overcome this, we employ the (IFSA) method of [1] to locate phase- and shut-invariant features. Membership scoring functions play an important role to classify genes since linear decomposition models basically aim at data reduction not but at grouping data. We address a new function essential to the IFSA method. In this paper we stress that IFSA is useful in grouping functionally-related genes in the presence of time-shift and expression phase variance. Ultimately, we propose a new approach to investigate the multiple interaction information of genes.

Hybrid Scheme of Data Cache Design for Reducing Energy Consumption in High Performance Embedded Processor (고성능 내장형 프로세서의 에너지 소비 감소를 위한 데이타 캐쉬 통합 설계 방법)

  • Shim, Sung-Hoon;Kim, Cheol-Hong;Jhang, Seong-Tae;Jhon, Chu-Shik
    • Journal of KIISE:Computer Systems and Theory
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    • v.33 no.3
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    • pp.166-177
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    • 2006
  • The cache size tends to grow in the embedded processor as technology scales to smaller transistors and lower supply voltages. However, larger cache size demands more energy. Accordingly, the ratio of the cache energy consumption to the total processor energy is growing. Many cache energy schemes have been proposed for reducing the cache energy consumption. However, these previous schemes are concerned with one side for reducing the cache energy consumption, dynamic cache energy only, or static cache energy only. In this paper, we propose a hybrid scheme for reducing dynamic and static cache energy, simultaneously. for this hybrid scheme, we adopt two existing techniques to reduce static cache energy consumption, drowsy cache technique, and to reduce dynamic cache energy consumption, way-prediction technique. Additionally, we propose a early wake-up technique based on program counter to reduce penalty caused by applying drowsy cache technique. We focus on level 1 data cache. The hybrid scheme can reduce static and dynamic cache energy consumption simultaneously, furthermore our early wake-up scheme can reduce extra program execution cycles caused by applying the hybrid scheme.

Study on Dosimetry Used TLD Dosimeter and Body Mass Index at Total Body Irradiation (전신조사방사선치료에서 열형광선량계를 이용한 선량 측정과 체질량지수에 관한 고찰)

  • Seo, Dong-Rin;Kim, Yeon-Soo;Kim, Dae-Sup;Yoon, Hwa-Ryong;Back, Geum-Mun;Kwak, Jung-Won
    • The Journal of Korean Society for Radiation Therapy
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    • v.23 no.2
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    • pp.91-96
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    • 2011
  • Purpose: The aim of study is to expose a more uniform dose depending on the relationship between a body mass index in patients who underwent radiation therapy and an acquired dosimetric information by using a thermoluminescent dosimeter. Materials and Methods: Since 2006 to August 2011 we investigated 28 people who underwent radiation therapy were enrolled in AMC. Each patient was measured on the head, neck, chest, abdomen, pelvis, thigh, knee joint, and ankle joint using the thermoluminescent dosimeter. The measurement value of each points compared with the prescribed center point, abdominal point, and dose measurements of points on which to base the abdomen and the patient's body mass index (BMI) were compared with reference point, abdomen dose. Results: 28 patients on prescribed dose in the abdomen by which the center point, an average dose was $100.6{\pm}5.5%$, and the other seven measuring points with the average maximum difference among the head, neck, chest, pelvic, thigh, knee, and ankle were $92.8{\pm}4.2%$, $97.6{\pm}6.2%$, $96.4{\pm}5.5%$, $102.6{\pm}5.3%$, $103.4{\pm}7.9%$, $95.8{\pm}5.9%$, $96.1{\pm}5.5%$. The relationship of abdominal point dose and the patient's body mass index (BMI) was analyzed a scatter plot, and the result of linear relationship analysis by regression method, the regression of the dose (y) was -1.009 BMI (x) plus 123.3 and coefficient of determination ($R^2$) was represented 0.697. Conclusion: The total body irradiation treatment process was evaluated the dose deviation and then the prescribed dose by which the average abdominal dose was satisfied with $100.6{\pm}5.5%$. Results of the relationship analysis between BMI and dose, if we apply the correction value for each patients, it can be achieved more uniform dose delivery.

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The Prime Counting Function (소수계량함수)

  • Lee, Sang-Un;Choi, Myeong-Bok
    • Journal of the Korea Society of Computer and Information
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    • v.16 no.10
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    • pp.101-109
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    • 2011
  • The Riemann's zeta function $\zeta(s)$ has been known as answer for a number of primes $\pi$(x) less than given number x. In prime number theorem, there are another approximation function $\frac{x}{lnx}$,Li(x), and R(x). The error about $\pi$(x) is R(x) < Li(x) < $\frac{x}{lnx}$. The logarithmic integral function is Li(x) = $\int_{2}^{x}\frac{1}{lnt}dt$ ~ $\frac{x}{lnx}\sum\limits_{k=0}^{\infty}\frac{k!}{(lnx)^k}=\frac{x}{lnx}(1+\frac{1!}{(lnx)^1}+\frac{2!}{(lnx)^2}+\cdots)$. This paper shows that the $\pi$(x) can be represent with finite Li(x), and presents generalized prime counting function $\sqrt{{\alpha}x}{\pm}{\beta}$. Firstly, the $\pi$(x) can be represent to $Li_3(x)=\frac{x}{lnx}(\sum\limits_{t=0}^{{\alpha}}\frac{k!}{(lnx)^k}{\pm}{\beta})$ and $Li_4(x)=\lfloor\frac{x}{lnx}(1+{\alpha}\frac{k!}{(lnx)^k}{\pm}{\beta})}k\geq2$ such that $0{\leq}t{\leq}2k$. Then, $Li_3$(x) is adjusted by $\pi(x){\simeq}Li_3(x)$ with ${\alpha}$ and error compensation value ${\beta}$. As a results, this paper get the $Li_3(x)=Li_4(x)=\pi(x)$ for $x=10^k$. Then, this paper suggests a generalized function $\pi(x)=\sqrt{{\alpha}x}{\pm}{\beta}$. The $\pi(x)=\sqrt{{\alpha}x}{\pm}{\beta}$ function superior than Riemann's zeta function in representation of prime counting.

Estimation of Groundwater Table using Ground Penetration Radar (GPR) in a Sand Tank Model and at an Alluvial Field Site (실내 모형과 현장 충적층에서 지하투과레이더를 이용한 지하수면 추정)

  • Kim, Byung-Woo;Kim, Hyoung-Soo;Choi, Doo-Houng;Koh, Yong-Kwon
    • The Journal of Engineering Geology
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    • v.23 no.3
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    • pp.201-216
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    • 2013
  • Ground penetrating radar (GPR) surveys were conducted in a sand tank model in a laboratory and at an alluvial field site to detect the groundwater table and to investigate the influence of saturation on GPR response in the unsaturated zone. In the sand tank model, the groundwater table and saturation in the sand layer were altered by injecting water, which was then drained by a valve inserted into the bottom of the tank. GPR vertical reflection profile (VRP) data were obtained in the sand tank model for rising and lowering of the groundwater table to estimate the groundwater table and saturation. Results of the lab-scale model provide information on the sensitivity of GPR signals to changes in the water content and in the groundwater table. GPR wave velocities in the vadose zone are controlled mainly by variations in water content (increased travel time is interpreted as an increase in saturation). At the field site, VRP data were collected to a depth of 220 m to estimate the groundwater table at an alluvial site near the Nakdong river at Iryong-ri, Haman-gun, South Korea. Results of the field survey indicate that under saturated conditions, the first reflector of the GPR is indicative of the capillary fringe and not the actual groundwater table. To measure the groundwater table more accurately, we performed a GPR survey using the common mid-point (CMP) method in the vicinity of well-3, and sunk a well to check the groundwater table. The resultant CMP data revealed reflective events from the capillary fringe and groundwater table showing hyperbolic patterns. The normal moveout correction was applied to evaluate the velocity of the GPR, which improved the accuracy of saturation and groundwater table information at depth. The GPR results show that the saturation information, including the groundwater table, is useful in assessing the hydrogeologic properties of the vadose zone in the field.

Development of a deep-learning based tunnel incident detection system on CCTVs (딥러닝 기반 터널 영상유고감지 시스템 개발 연구)

  • Shin, Hyu-Soung;Lee, Kyu-Beom;Yim, Min-Jin;Kim, Dong-Gyou
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.19 no.6
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    • pp.915-936
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    • 2017
  • In this study, current status of Korean hazard mitigation guideline for tunnel operation is summarized. It shows that requirement for CCTV installation has been gradually stricted and needs for tunnel incident detection system in conjunction with the CCTV in tunnels have been highly increased. Despite of this, it is noticed that mathematical algorithm based incident detection system, which are commonly applied in current tunnel operation, show very low detectable rates by less than 50%. The putative major reasons seem to be (1) very weak intensity of illumination (2) dust in tunnel (3) low installation height of CCTV to about 3.5 m, etc. Therefore, an attempt in this study is made to develop an deep-learning based tunnel incident detection system, which is relatively insensitive to very poor visibility conditions. Its theoretical background is given and validating investigation are undertaken focused on the moving vehicles and person out of vehicle in tunnel, which are the official major objects to be detected. Two scenarios are set up: (1) training and prediction in the same tunnel (2) training in a tunnel and prediction in the other tunnel. From the both cases, targeted object detection in prediction mode are achieved to detectable rate to higher than 80% in case of similar time period between training and prediction but it shows a bit low detectable rate to 40% when the prediction times are far from the training time without further training taking place. However, it is believed that the AI based system would be enhanced in its predictability automatically as further training are followed with accumulated CCTV BigData without any revision or calibration of the incident detection system.

A Case Study on Forecasting Inbound Calls of Motor Insurance Company Using Interactive Data Mining Technique (대화식 데이터 마이닝 기법을 활용한 자동차 보험사의 인입 콜량 예측 사례)

  • Baek, Woong;Kim, Nam-Gyu
    • Journal of Intelligence and Information Systems
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    • v.16 no.3
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    • pp.99-120
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    • 2010
  • Due to the wide spread of customers' frequent access of non face-to-face services, there have been many attempts to improve customer satisfaction using huge amounts of data accumulated throughnon face-to-face channels. Usually, a call center is regarded to be one of the most representative non-faced channels. Therefore, it is important that a call center has enough agents to offer high level customer satisfaction. However, managing too many agents would increase the operational costs of a call center by increasing labor costs. Therefore, predicting and calculating the appropriate size of human resources of a call center is one of the most critical success factors of call center management. For this reason, most call centers are currently establishing a department of WFM(Work Force Management) to estimate the appropriate number of agents and to direct much effort to predict the volume of inbound calls. In real world applications, inbound call prediction is usually performed based on the intuition and experience of a domain expert. In other words, a domain expert usually predicts the volume of calls by calculating the average call of some periods and adjusting the average according tohis/her subjective estimation. However, this kind of approach has radical limitations in that the result of prediction might be strongly affected by the expert's personal experience and competence. It is often the case that a domain expert may predict inbound calls quite differently from anotherif the two experts have mutually different opinions on selecting influential variables and priorities among the variables. Moreover, it is almost impossible to logically clarify the process of expert's subjective prediction. Currently, to overcome the limitations of subjective call prediction, most call centers are adopting a WFMS(Workforce Management System) package in which expert's best practices are systemized. With WFMS, a user can predict the volume of calls by calculating the average call of each day of the week, excluding some eventful days. However, WFMS costs too much capital during the early stage of system establishment. Moreover, it is hard to reflect new information ontothe system when some factors affecting the amount of calls have been changed. In this paper, we attempt to devise a new model for predicting inbound calls that is not only based on theoretical background but also easily applicable to real world applications. Our model was mainly developed by the interactive decision tree technique, one of the most popular techniques in data mining. Therefore, we expect that our model can predict inbound calls automatically based on historical data, and it can utilize expert's domain knowledge during the process of tree construction. To analyze the accuracy of our model, we performed intensive experiments on a real case of one of the largest car insurance companies in Korea. In the case study, the prediction accuracy of the devised two models and traditional WFMS are analyzed with respect to the various error rates allowable. The experiments reveal that our data mining-based two models outperform WFMS in terms of predicting the amount of accident calls and fault calls in most experimental situations examined.

A Basic Study for the Retrieval of Surface Temperature from Single Channel Middle-infrared Images (단일 밴드 중적외선 영상으로부터 표면온도 추정을 위한 기초연구)

  • Park, Wook;Lee, Yoon-Kyung;Won, Joong-Sun;Lee, Seung-Geun;Kim, Jong-Min
    • Korean Journal of Remote Sensing
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    • v.24 no.2
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    • pp.189-194
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    • 2008
  • Middle-infrared (MIR) spectral region between 3.0 and $5.0\;{\mu}m$ in wavelength is useful for observing high temperature events such as volcanic activities and forest fire. However, atmospheric effects and sun irradiance in day time has not been well studied for this MIR spectral band. The objectives of this basic study is to evaluate atmospheric effects and eventually to estimate surface temperature from a single channel MIR image, although a typical approach utilize split-window method using more than two channels. Several parameters are involved for the correction including various atmospheric data and sun-irradiance at the area of interest. To evaluate the effect of sun irradiance, MODIS MIR images acquired in day and night times were used for comparison. Atmospheric parameters were modeled by MODTRAN, and applied to a radiative transfer model for estimating the sea surface temperature. MODIS Sea Surface Temperature algorithm based upon multi-channel observation was performed in comparison with results from the radiative transfer model from a single channel. Temperature difference of the two methods was $0.89{\pm}0.54^{\circ}C$ and $1.25{\pm}0.41^{\circ}C$ from the day-time and night-time images, respectively. It is also shown that the emissivity effect has by more largely influenced on the estimated temperature than atmospheric effects. Although the test results encourage using a single channel MR observation, it must be noted that the results were obtained from water body not from land surface. Because emissivity greatly varies on land, it is very difficult to retrieval land surface temperature from a single channel MIR data.

A Study on the Possibility of Producing a Floor Plan of 「Donggwoldo(東闕圖)」 through the Use of Rubber Sheeting Transformation - With a Focus on the Surroundings near the Geumcheongyo Bridge in Changdeokgung Palace - (러버쉬팅변환을 통한 「동궐도(東闕圖)」의 평면도 제작 가능성 연구 - 창덕궁 금천교 주변을 중심으로 -)

  • Lee, Jae-Yong;Kim, Young-Mo
    • Korean Journal of Heritage: History & Science
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    • v.50 no.4
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    • pp.104-121
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    • 2017
  • The present study attempted to produce the floor plan of the surroundings near Geumcheongyo Bridge in Changdeokgung Palace of the Late Joseon Period through the use of rubber sheeting transformation based on the drawing principles of "Donggwoldo(東闕圖)". First, the study compared the actual sizes of the major buildings that have existed since the production of "Donggwoldo(東闕圖)" with the sizes depicted in the picture to reveal that the front elevation of the buildings was produced by reducing it by approximately 1/200. However, the study could not confirm the same production proportions for the side elevation. Only the lengths of the side elevation were depicted at around half of the actual proportions, and as the diagonal line angles were found to be at an average of $39^{\circ}$, the study confirmed they were drawn in a manner similar to cabinet projection. Second, the study created an obliquely projected floor plan by inversely shadowing the drawing principles of "Donggwoldo(東闕圖)" and produced a floor plan of the surroundings near Geumcheongyo Bridge in Changdeokgung Palace through the use of rubber sheeting transformation. Projective transformation was confirmed as most suitable during the transformation, and with standard error of 2.1208m, the relatively high accuracy of the transformation shows that the production of a floor plan for "Donggwoldo(東闕圖)" is significant. Furthermore, it implies the possibility of producing floor plans for various documentary paintings produced using the paralleled oblique drawing method in addition to "Donggwoldo(東闕圖)". Third, the study evaluated the accuracy of the spatial information provided by the produced floor plan by comparing the three items of Geumcheongyo Bridge location, Geumcheongyo Bridge and Jinseonmun Gate arrangement, and Geumcheon stone embankment location. The results confirmed the possibility of utilizing the floor plan as a useful tool which helps understand the appearance of the surroundings at the time of "Donggwoldo(東闕圖)" production because it is parallel to the excavation results of the Geumcheongyo Bridge and its context. Therefore, the present study is significant in that it seeks the possibility of producing spatial information recorded in "Donggwoldo(東闕圖)" by applying rubber sheeting transformation and consequently in that it presents a new methodology for understanding the appearance of the East Palace of the Late Joseon Period.

Evaluation of Land Use Change Impact on Hydrology and Water Quality Health in Geum River Basin (금강유역의 토지이용 변화가 수문·수질 건전성에 미치는 영향 평가)

  • LEE, Ji-Wan;PARK, Jong-Yoon;JUNG, Chung-Gil;KIM, Seong-Joon
    • Journal of the Korean Association of Geographic Information Studies
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    • v.22 no.2
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    • pp.82-96
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    • 2019
  • This study evaluated the status of watershed health in Geum River Basin by SWAT (Soil and Water Assessment Tool) hydrology and water quality. The watershed healthiness from watershed hydrology and stream water quality was calculated using multivariate normal distribution from 0(poor) to 1(good). Before evaluation of watershed healthiness, the SWAT calibration for 11 years(2005~2015) of streamflow(Q) at 5 locations with 0.50~0.77 average Nash-Sutcliffe model efficiency and suspended solid (SS), total nitrogen(T-N), and total phosphorus(T-P) at 3 locations with 0.67~0.94, 0.59~0.79, and 0.61~0.79 determination coefficient($R^2$) respectively. For 24 years (1985~2008) the spatiotemporal change of watershed healthiness was analyzed with calibarted SWAT and 5 land use data of 1985, 1990, 1995, 2000, and 2008. The 2008 SWAT results showed that the surface runoff increased by 40.6%, soil moisture and baseflow decreased by 6.8% and 3.0% respectively compared to 1985 reference year. The stream water quality of SS, T-N, and T-P increased by 29.2%, 9.3%, and 16.7% respectively by land development and agricultural activity. Based on the 1985 year land use condition. the 2008 watershed healthiness of hydrology and stream water quality decreased from 1 to 0.94 and 0.69 respectively. The results of this study be able to detect changes in watershed environment due to human activity compared to past natural conditions.