• Korean Journal of Biological Psychiatry
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• v.4 no.1
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• pp.102-107
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• 1997

Ginseng root, as a folk medicine, has been used in far eastern countries for thousands of years. Ginseng extract has been shown to have a variety of effects on the activity of the central nervous system, promoting stimulation as well as inhibition of the cortical activity. A survey of the relevant literatures has indicated that the putative anxiolytic activity of red ginseng has not been scientifically investigated. Therefore, the present study was designed to assess anxiolytic effect of gingseng total saponins(GTS). The putative anxiolytic effects of several fractions of GTS were investigated in mice using an elevated plus maze paradigm. Single dose administration of TS Fr.-I showed anxiolytic action in mice. Anxiolytic effect induced by TS Fr.-I was similar to that induced by diazepam. TS Fr.-II, TS Fr.-III and TS Fr.-IV did not show the anxiolytic action compared with that of TS Fr.-I. It was suggested that regulation of GABAergic neurotransmission may be important in the action of GTS. The Interaction of GTS fractions with benzodiazepine receptor was performed using rat cortical membranes. GTS inhibited the binding of [3H] Ro 15-1788 on the benzodiazepine receptor. Among from TS fractions, the binding activity of GTS in the TS Fr.-IV was highest, which did not show the anxiolytic activity. From these results, we conclude that GTS has anxiolytic action, and this is not related to benzodiazepine receptor binding activity.

• Journal of Yeungnam Medical Science
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• v.3 no.1
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• pp.131-138
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• 1986

The authors studied anxiety, using Zung's Self-Rating Anxiety Scale(SAS), in the subjects of 3,499 male and 1,335 female college freshmen of Yeungnam University. The authors collected the reports of SAS during the periods from January to February, 1986, and applied ANOVA and t-test on anxiety scores in order to compare them between various psychosocial factors, and sexes. The results are as follows: There was significant difference in the mean averages of total anxiety scores between male and female students: male students scored $32.91{\pm}7.70$, female students scored $34.48{\pm}6.00$, (P<0.001). The anxiety scores relating to the items of sweating, apprehension, restlessness, and insommia were relatively higher in both groups. The anxiety scores relating to the items of faintness, mental disintegration, tremors, dizziness were lower in both groups. Thirty-nine male students(1.1%) showed seriously high anxiety scores of 50 or higher, while twenty-one female students(1.6%) showed the same scores. So the authors inferred that the features of anxiety symptoms were much the same in our country, but female showed more various symptoms and higher level of anxiety than males. Male students attending in pharmacy showed higher level of anxiety scores(P<0.01). There was a strong tendency toward higher anxiety scores in the students who were dissatisfied with their home atmosphere, colleges, department and familiarity of parents, and those who had pessimistic views of self image in the past, present, or future, in both groups(P<0.001).

• Journal of Yeungnam Medical Science
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• v.2 no.1
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• pp.113-122
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• 1985

The authors studied anxiety, using Zung's Self-Rating Anxiety Scale (SAS), in the subjects of 3,893 male and 1,976 female college students of Yeungnam University. The authors collected the reports of SAS during the periods from October to November, 1984, and applied ANOVA and t-test on the anxiety scores in order to compare them between various psychosocial factors, and sexes. The results could be summarized as follows: There was significant difference in the mean averages of total anxiety score's between male and female students ; male students scored $36.92{\pm}7.07$, female students scored $39.63{\pm}7.51$, p<0.001. The anxiety scores relating to the items of sweating, apprehension, restlessness, insommia, dyspnea were relatively higher in both groups. The anxiety scores in the items of paresthesias, mental disintegration, tremors, faintness, dizziness were lower in both groups. Two hundred and one male students (5.2%) showed seriously high anxiety scores of 50 or higher, while 201 female students (10.2%) showed the same scores. So the authors inferred that the features of anxiety symptoms were much the same in our country, but females showed more various symptoms and higher level of anxiety than males. In a comparison between male students in different school grades, freshmen showed the highest level of anxiety scores and as the grades of the students became higher, the levels of anxiety scores were lower. The female students who resided in dormitory or other residences, and whose educational fees were paid by brothers or sisters, showed higher level of anxiety scores. There was a strong tendency toward higher anxiety scores in the students who were dissatisfied with their colleges or departments, and who had pessimistic views of self image in the past, present, or future, in both groups.

• Anxiety and mood
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• v.13 no.2
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• pp.93-99
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• 2017

Objective : This study aimed to evaluate the association of exhaustion, ADHD, self-esteem, impulsivity, suicidal tendencies and quality of life as well as depression and anxiety in fire officers in Korea. Methods : This study was undertaken for the first time in Korea, from September 2016 to December 2016. A set of questionnaires was provided to a total of 113 fire officers and 284 other participants as a comparison group. All subjects were evaluated using the Beck's Depression Inventory, Beck's Anxiety Inventory, Malach Burnout Inventory, Korean Adult Attention Deficit Hyperactivity Disorder Scales, Rosenberg's Self-esteem Inventory, Baratt's Impulsivity Scale, Beck's Scale of Suicide Ideation, and Quality of Life Scale. Furthermore, the odds ratio of depression, anxiety, exhaustion, ADHD, self-esteem, impulsivity, suicidal tendency and quality of life were evaluated the fire officer group and control group were compared through logistic regression analysis. Result : The results of this study indicated that the fire officers were more likely to show depression, anxiety, exhaustion, ADHD, low self-esteem and higher impulsivity. Also, the association between the fire officer group and depression, ADHD and impulsivity was confirmed through logistic regression analysis. Conclusion : Timely and effective evaluation and treatment of impulsivity, as well as depression is required for fire officers.

• Anxiety and mood
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• v.9 no.2
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• pp.147-153
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• 2013

Objective : Despite the chronic nature and high social costs, individuals with anxiety disorders seldom seek treatment. Thus, education for public awareness and screening for the illness is tremendously important for mental health professionals. This study summaries and presents the results from Anxiety Disorder Screening Program during the Mental Health Exposition held in Seoul in April, 2013. Methods : We analyzed the data from 116 participants who agreed and completed the screening questionnaires during their visits to two-day Anxiety Disorder Screening Program prepared by the Korean Academy of Anxiety Disorder. The questionnaire comprised of modified Mobility inventory for agoraphobia, Contents of worries, Penn State Worry Questionnaire, Life Events Checklist, and Abbreviated Posttraumatic Stress Disorder Checklist. Results : Participants demonstrated high rates of anxiety symptoms and possible anxiety disorders. Experience of panic attack was reported by 45%, lifetime and 16% in the past month by respondents. Phobia was reported by 46%. Participants had an average of 3.3 pathological worries and among those, social or interpersonal content was most common (46%). At least one lifetime traumatic event was reported by 64%. By the cut-off scores in the literature, 46% had possible generalized anxiety disorder and 58% possible posttraumatic stress disorder. Conclusion : Our results suggested that many visitors to Anxiety Disorder Screening Program were in fact treatment seeking after experiencing some forms of anxiety symptoms. Further efforts for delivery of medical information and increasing public awareness for anxiety disorders are needed.

• Anxiety and mood
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• v.2 no.2
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• pp.136-141
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• 2006

Objectives : This study aimed to investigate the therapeutic effect of combined biofeedback training with pharmacotherapy for patients with anxiety disorder. Methods : 12 patients with panic disorder and generalized anxiety disorder were enrolled this study. They were tested for State Trait Anxiety Inventory-State (STAI-S), State Trait Anxiety Inventory-Trait (STAI-T), Beck's Depression Inventory (BDI) and Symptom CheckList-90-Revision Somatization (SCL-90-R-SOM) before and after the biofeedback training program. Results : The score of STAI-T (p=0.023) and BDI (p=0.0018) were the significantly decreased after the biofeedback training program. In Female group, the score of STAI-T (p=0.028), STAI-S (p=0.028) and BDI (p=0.009) were significantly decreased after the biofeedback training program. In the group which age is lower than 40 years old, the score of BDI (p=0.046) were significantly decreased after the biofeedback training program. In Panic disorder group, the score of STAI-S (p=0.046) were significantly decreased after the biofeedback training program. Conclusion : The result of this study is useful for the treating the anxiety disorder patients using the biofeedback training program.

• Anxiety and mood
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• v.13 no.2
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• pp.100-107
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• 2017

Objective : The purpose of this study was to investigate strategies used to cope with stress and the cognitive characteristics of somatic symptom perception in patients with generalized anxiety disorder(GAD). Methods : A total of 55 patients meeting DSM-5 criteria for GAD and 55 normal controls were recruited for participation in this study. We evaluated subjects using The Way of Stress Coping Questionnaire (SCQ), Somato-Sensory Amplification Scale (SSAS), Symptom Interpretation Questionnaire (SIQ), and the Generalized Anxiety Disorder for 7 Item (GAD-7). We analyzed data using an independent t-test and Pearson's correlation analysis. Results : In terms of SCQ, GAD patients presented significantly lower scores on seeking social support and higher scores on wishful thinking than normal controls. GAD patients had significantly greater amplification of physical sensation in SSAS and higher scores in physical, psychological interpretation subsets of SIQ than normal controls. GAD-7 scores were positively correlated with physical interpretation scores on SIQ. Conclusion : Results reveal that patients with GAD have insufficient coping strategies for stress, greater amplification of body sensations, and tendency towards a physical, psychological interpretation of somatic symptoms.

• Journal of Yeungnam Medical Science
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• v.4 no.2
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• pp.29-38
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• 1987

The authors studied anxiety-depression using New Anxiety-Depression Scale (NADS) in the subjects of 2.564 male and 1,252 female college freshmen of Yeungnam University. The authors collected the reports of NADS during the periods from January to February 1987, and applied NAOVA and t-test on anxiety depression scores in order to compare them between various psychosocial factors and sexes. The results are as follows : There was significant difference in the mean average of total scores between male and female students : male students scored $33.41{\pm}8.76$ and female students scored $35.34{\pm}9.02$ (P<0.001). The anxiety-depression scores relating to the items of sleep disturbance, apprehension, facial flushing and fatigue were relatively scored higher in both groups. One hundred and thirty nine male students (5.4%) showed seriously higher degree of anxiety-depression scores of 50 or more, while eighty eight female students (7.0%) showed the sane scores. There was a strong tendency toward higher anxiety-depression scores in the students who were dissatisfied with their home atmosphere, colleges, departments, familiarity of parents am those who had pessimistic views of self image in the past, presents and future in both groups (P<0.001).

• Anxiety and mood
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• v.8 no.2
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• pp.79-85
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• 2012

Objective : The current study investigated the psychopathology characteristics of the suicide attempter visited in a university hospital for one year using the Minnesota Multiphasic Personality Inventory (MMPI) test commonly used in clinical medicine. Methods : 72 suicide attempter and 115 control group completed the Korean version of the MMPI. Results : The MMPI scores of the suicide attempters were significantly higher on the lie (L), infrequency (F), defensiveness (K), paranoia (Pa), psychasthenia (Pt), schizophrenia (Sc), hypomania (Ma) than the comparison group. Conclusion : We supposed that suicide attempter have more chance of being paranoid, psychasthenic, schizoid or hypomanic than the control group relatively. They seem to have psychotic psychopathology rather than neurotic psychopathology. These results suppoed that the psychopatholgy of suicide attempter may be different from the control group. However the final decision is indefinite, it needs more well designed systemic studies.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.4 no.1
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• pp.124-132
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• 1993

We studied the clinical characteristics of 45 children with tic symptoms, and a comparison was made according to their birth order patterns. The results were as follows. Sex ration was 14:1 higher for boys. The eldest children were 46.7%, single children, 15.6%, the youngest children, 33.3%, and twins 4.4% of all Organicity was suggested in 37.8%, early developmental problems in 71.1%, and family problems were in 89.9%. Among the co-existing problems, ADHD 46.7%, OCD 17.7%, Separation anxiety disorder 24.4%, GAD or anxiety dreams 17.8%, somatization disorder and enuresis 13.3% each, stuttering 8.9%, and other conditions. Overall, 84.4% of the patients have one or more co-existing conditions other than tic symptoms. When compared according to birth order patterns, the most significant difference was the time of onset The youngests have more incidences around the entrance period for elementary school(p<0.01). Among the twins, the lower birth-weight child was the patient. Summing up these findings, we concluded there were significant environmental factors working on the manifestation of tic and tourette disorders.