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Effect of Korean Red Ginseng on Sleep : A Randomized, Placebo-Controlled Trial (고려 홍삼이 수면의 질에 미치는 영향 : 무작위 위약-대조군 연구)

  • Lee, Sun-Ah;Kang, Seung-Gul;Lee, Heon-Jeong;Jung, Ki-Young;Kim, Leen
    • Sleep Medicine and Psychophysiology
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    • v.17 no.2
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    • pp.85-90
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    • 2010
  • Objectives: Ginseng has a long history of being used in insomnia treatment and there is some evidence from animal studies of its sleep-enhancing property. From this, it can be assumed that ginseng has sleep-promoting effect in humans. The purpose of this study was to investigate the effect of Korean red ginseng on change of sleep architecture in humans. Methods: A total of 20 healthy young males with regular sleep and wake habits and without any psychiatric nor cognitive problems were selected based on review of sleep questionnaires and sleep diaries they completed followed by an interview with a board-certified psychiatrist. The subjects were randomly assigned to red ginseng or placebo for 2 weeks of trial. The total daily dose of ginseng was 4,500 mg. The polysomnographic recordings were made at baseline and at 2 weeks after. The effects of red ginseng and placebo on sleep were assessed by comparing the changes in polysomnographic variables between the two groups. Results: A total of 15 subjects, 8 from red ginseng group and 7 from placebo group, were included to undergo polysomnographic procedures. The red ginseng group showed tendencies to increase stage 3 sleep (p=0.087) and to decrease stage 2 sleep (p=0.071) from the baseline compared with the placebo group. Conclusion: Korean red ginseng tends to increase deep sleep and decrease shallow sleep. Our result is in line, at least in part, with previous findings that Korean red ginseng increased total and NREM sleep in rats. Further studies with higher ginseng dosage, larger sample size and longer trial duration should be conducted to confirm the sleep stabilizing and balancing effects of Korean red ginseng.

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Estimating Method of Starting Point Bias in Bidding Game (서베이를 이용한 입찰게임에서 출발점 편의의 추정)

  • 박용치
    • Survey Research
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    • v.4 no.2
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    • pp.63-86
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    • 2003
  • The objective of this study was to investigate the existence of starting point bias in the bidding game contingent valuation elicitation technique when determining willingness to pay (WTP) for improving the qualify of running water in Seoul and its vicinity. Of all existing contingent techniques, the bidding game most closely mimics the normal price taking behavior in local markets. Three different starting points (low, medium and high) were used to determine WTP and the existence of starting point bias in the meanwhile respectively. The respondents were randomly assigned to the three different starting point groups in order to ensure homogeneity, so that any variation seen in WTP could be attributed to the starting point effects. And a pretested interviewer-administered questionnaire used to elicit WTP. Non-parametric test and the logit model were used to analyze the data for evidence of starting point bias. In this instance, the high starting point group had a high WTP, and low starting point group had a low WTP. This means there exist starting point bias in estimating WTP by bidding game in this instance. This finding might signal that people may actually be making up their minds on the maximum amount they are willing to pay for running water service as a bidding iterating is going on and is influenced by the starting point used in the bidding game. The problem of slaking point bias can be avoided if the respondent is asked directly for the maximum WTP without payment cards or a bidding game. But such a question is perceived as being very difficult to answer and this leads to problems of non-response and being unrealistic.

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Antimutagenic and Antimicrobial Effect of Cucumber (Cucumis sativus) Extracts (오이 추출물의 항돌연변이 및 항미생물 효과)

  • 정숙현;문숙희
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.30 no.6
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    • pp.1164-1170
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    • 2001
  • Antimutagenic and antimicrobial effects of cucumber extracts were investigated. Antimutagenic effects of cucumber extract against aflatoxin (AFB$_1$) as indirect mutagen and N-methyl-N'-nitro-N-nitrcsoguanidine (MNNG) as direct mutagen using the Ames assay system with Salmonella typhimurium TA100 were studied. 1.25~5.0% of methanol extract exhibited 11 ~ 17% of antimutagenity against AFB$_1$ and 46~85% of antimutagenity against MNNG. Among fractions of methanol extract, hexane fraction exhibited the highest antimutagenic effect against AFB$_1$ (89%) and butanol fraction exhibited the highest antimutagenic effect against MNNG (95%). Antimicrobial effects of cucumber extract were investigated on the eleven microorganisms. Methanol extract showed anitimicrobial effect on eight microorganisms. Among these tested microorganisms, Klebsiella pnemonia KCTC 2208, pseudomonas aeruginosa KCTC 2004 were the most sensitively inhibited with 13 mm clear zone on holo test. Hexane fraction showed anitimicrobial effect only on Vibrio parahaemolyticus KCTC 2471. Chloroform and ethyl acetate fractions showed a weak effect. V. parahaemolyticus showed the lowest minium inhibitory concentration (MIC) (500 ppm) among eleven tested microorganisms by methanol extract. Sterilization effect of 1% methanol extract on P. aeruginosa incubation is 10 times stronger than 0.5% methanol extract. It estimated to need 26 min for the sterilization of 90% P. aeruginosa cell counts by 1% methanol extract but 250 min by 0.5% methanol extract.

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The Comparison of Food Constituent in Different Parts of Pumpkin (늙은 호박의 부위별 성분 비교)

  • Jang, Sang-Moon;Park, Nan-Young;Lee, Joo-Baek;Ahn, Hong
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.30 no.6
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    • pp.1038-1040
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    • 2001
  • This study was conducted to investigate the constituents of pumpkin, to develop of health food using pumpkin. Crude protein contents of skin (19.82%) and fiber (16.43%) were higher than that of flesh. Crude lipids contents of skin (2.84% ) was higher than those of flesh and fiber. Major free sugars in pumpkin were sucrose, fructose and glucose. Total sugar contents in the flesh was higher than that of fiber. This tendency was opposite to reducing sugar contents. Also, free sugar contents in pumpkin were flesh (30.19 mg/100 g), fiber (22.99 mg/100 g) and skin (15.67 mg/100 g), respectively. The total Phenol and carotenoid contents in 100 g of fiber revealed 379.8$\pm$9.76 mg and 43.71$\pm$1.46 mg, corresponding to 47% and 62% of the total phenol and carotenoid contents of pumpkin. Total flavonoid content in 100 g of skin revealed 81.5$\pm$3.56 mg.

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Studies on the Stabilities of Red Pepper Oleoresin (고추 oleoresin의 품질안정성(品質安定性))

  • Kim, Chie-Soon;Lee, Gyu-Hee;Bae, Jung-Seul;Oh, Man-Jin
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.16 no.3
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    • pp.85-90
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    • 1987
  • This experiment was carried out to study the preparations of red pepper oleoresin, the effects of pH and heat treatment on the stabilities of capsanthin and capsaicin in oleoresin state, and the interacting effects of ascorbic acid, metal salts and EDTA on the stabilities of capsanthin in the oleoresin-linoleate aqueous model system. The results were as follows: 1. Acetone was the most effective solvent to extract capsanthin and capsaicin from red pepper powder. The yield of oleoresin extracted with acetone was 14.27%. 2. Capsaicin was more stable at high temperature than capsanthin in oleoresin state. Capsanthin and capsaicin in oleoresin state were comparatively stable in the range (ron) pH 3 to pH 8. 3. Ascorbic acid acted as a prooxidant on the capsanthin oxidation reaction at concentrations up to $10^{-3}M$, but acted as an antioxidant at $10^{-1}M$. 4. The addition of $Cu^{+2}M$ and $Fe^{+3}M$ ions at all concentration increased the prooxidant activity on the degradation of capsanthin in oleoresin state. 5. EDTA showed a strong antioxidation the stability of capsanthin in oleoresin state.

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Comparison of Functional Properties of Cheonggukjang by Using Red Ginseng (홍삼을 이용한 청국장의 기능적 특성 비교)

  • Park, Nan-Young;Seong, Jong-Hwon;Choi, Myung-Sook;Moon, Kwang-Deog;Kwon, Joong-Ho;Jeong, Yong-Jin
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.37 no.3
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    • pp.261-268
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    • 2008
  • To utilize Cheonggukjang as a raw material of diverse foods, the quality characteristics of Cheonggukjang and its processed food were compared. Cheonggukjang (CGJ), red ginseng Cheonggukjang (RCJ), and red ginseng Cheonggukjang hydrolysate (RCH) were powdered, and their quality and functional characteristics were examined. The result showed that in regard to general components, carbohydrate content of RCJ was higher than other samples while crude protein content was lower. Free amino acid content of RCH was 2,157.16 mg%, which was approximately 2 times higher than CGJ, and the content of essential amino acid was 812.18 mg%, which was the highest. The result of SDS-electrophoresis pattern showed that CGJ and RCJ showed a molecular weight smaller than 33 kDa, and RCH showed a smaller than 17 kDa low molecular weight, confirming the hydrolysis to small molecular weight. Among the samples, free radical scavenging activity, superoxide radical scavenging activity, and ACE inhibitory activity did not show a significant difference; nonetheless, RCH showed the highest activity while CGJ showed the highest fibrinolytic activity of 111.38 unit. In addition, in sensory evaluation, the peculiar bitter taste of red ginseng could be detected while the overall acceptability was improved. Based on the above results, in comparison with CGJ, as for RCJ and RCH, their function was strengthened and unpleasant odor was reduced, and thus it is anticipated that they could be used as a raw material of diverse foods.

Deformation Behavior and Slope Stability Effect of Anchored Retention Walls Installed in Cut Slope (절개사면에 설치된 앵커지지 합벽의 변형거동 및 사면안정효과)

  • Hong Won-Pyo;Han Jung-Geun
    • Journal of the Korean Geotechnical Society
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    • v.20 no.9
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    • pp.57-64
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    • 2004
  • In order to establish the design method of anchored retention walls in cut slope, the behavior of anchored retention walls and backside ground needs to be investigated and checked in detail. In this study, the behavior of anchored retention walls was investigated by instrumentation installed in cut slope for an apartment construction site stabilized by a row of piles and anchored retention walls. When the anchor was installed at each excavating stages, the horizontal deflection of retention wall decreased, while the horizontal deformation of backside ground increased. The deflection of anchored retention wall decreased as the anchor was prestressed. The prestressed anchor farce has a great effect on the deflection of retention walls, while it has little effect on the deformation of its backside ground. The maximum horizontal deflection of anchored retention walls was developed between $1\%\;and\;4\%$ of excavation depth, which are $2\~8$ times larger than max. horizontal deflection of anchored retention walls including rock layers with backside horizontal ground. Meanwhile, SLOPILE (ver. 3.0) program analyzes the slope stability effects for anchored retention walls. As a result of analysis on slope stability analysis, the lateral earth pressure applied at anchored retention piles could be used as the mean values of empirical lateral pressures using anchored retention wall with horizontal ground at its backside.

A Study on Fabrication and Performance Evaluation of Wideband 2-Mode HPA for the Satellite Mobile Communications System (이동위성 통신용 광대역 2단 전력제어 HPA의 구현 및 성능평가에 관한 연구)

  • 전중성;김동일;배정철
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.3 no.3
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    • pp.517-531
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    • 1999
  • This paper presents the development of the 2-mode variable gain high power amplifier for a transmitter of INMARSAT-M operating at L-band(1626.5-1646.5 MHz). This SSPA(Solid State Power Amplifier) is amplified 42 dBm in high power mode and 36 dBm in low power mode for INMARSAT-M. The allowable error sets +1 dBm of an upper limit and -2 dBm of a lower limit, respectively. To simplify the fabrication process, the whole system is designed by two parts composed of a driving amplifier and a high power amplifier, The HP's MGA-64135 and Motorola's MRF-6401 are used for driving amplifier, and the ERICSSON's PTE-10114 and PTF-10021 are used the high power amplifier. The SSPA was fabricated by the circuits of RF, temperature compensation and 2-mode gain control circuit in aluminum housing. The gain control method was proposed by controlling the voltage for the 2-mode. In addition, It has been experimentally verified that the gain is controlled for single tone signal as well as two tone signals. The realized SSPA has 42 dB and 36 dB for small signal gain within 20 MHz bandwidth, and the VSWR of input and output port is less than 1.5:1 The minimum value of the 1 dB compression point gets 5 dBm for 2-mode variable gain high power amplifier. A typical two tone intermodulation point has 32.5 dBc maximum which is single carrier backed off 3 dB from 1 dB compression point. The maximum output power of 43 dBm was achieved at the 1636.5 MHz. These results reveal a high power of 20 Watt, which was the design target.the design target.

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Effects of complex exercises in pressure-pain threshold, pain and postural alignment of women university students with shoulder pain (복합운동이 어깨통증을 경험한 여대생들의 압통역치, 통증 및 자세정렬에 미치는 영향)

  • Park, Chung-hyun;Woo, Jae-seung;Lee, Jae-hyun;Jo, Eun-jeong;Hwang, Su-jeong;Woo, Sung-hee;Kang, Soon-hee
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2017.05a
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    • pp.704-707
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    • 2017
  • The purpose of this study was to examine if complex exercises could improve pressure-pain threshold and postural alignment in university students. Subjects in the CON group did not receive an intervention. Subjects in the EXP1 group were applied stretching exercises after applying hot packs on their both shoulders. Subjects in the EXP2 group were applied complex exercises including stretching, stabilization exercises of shoulder girdle and correction of wrong postures. Changes in pressure-pain threshold in the EXP1 group and EXP2 group were greater than that in the CON group (p<0.05). Changes in VAS scores in the EXP1 group and EXP2 group were greater than that in the CON group (p<0.05). Changes of postural alignment did not significantly differ among three groups (p>0.05). The results of this study indicates that complex exercises including stretching exercises, stabilization exercises of shoulder girdle and correction of wrong postures about neck and scapular can be an effective in reduction of shoulder pain and increase of pressure-pain threshold in women university with shoulder pain.

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A Model for evaluating the efficiency of inputting Hangul on a telephone keyboard (전화기 자판의 한글 입력 효율성 평가 모형)

  • Koo, Min-Mo;Lee, Mahn-Young
    • The KIPS Transactions:PartD
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    • v.8D no.3
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    • pp.295-304
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    • 2001
  • The standards of a telephone Hangul keyboard should be decided in terms of objective factors : the number of strokes and fingers’moving distance. A number of designers will agree on them, because these factors can be calculated in an objective manner. So, We developed the model which can evaluate the efficiency of inputting Hangul on a telephone keyboard in terms of two factors. As compared with other models, the major features of this model are as follows : in order to evaluate the efficiency of Hangul input on a telephone keyboard, (1) this model calculated not a typing time but the number of strokes ; (2) concurrence frequency that had been counted on KOREA-1 Corpus was used directly ; (3) a total set of 67 consonants and vowels was used ; and (4) this model could evaluate a number of keyboards that use a kind of syllabic function key-the complete key, the null key and the final consonant key and also calculate a lot of keyboards that adopt no syllabic function key. However, there are many other factors to judge the efficiency of inputting Hangul on a telephone keyboard. If we want to make more accurate estimate of a telephone Hangul keyboard, we must consider both logical data and experimental data as well.

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