• Journal of the Korean Society of Radiology
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• v.17 no.1
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• pp.131-139
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• 2023

In this study, we are purposed to find the educational effect of practical training using a 3D printed structure-based blind box on multidimensional radiographic image interpretation. The subjects were 83 (male: 49, female: 34) 2nd year radiological science students who participated in the digital medical imaging practice that was conducted for 3 years from 2020 to 2022. The learning method used 3D printing technology to print out the inside structure of the blind box designed by itself. After taking X-rays 3 times (x, y, z axis), the structure images in the blind box were analyzed for each small group. We made the 3D structure that was self-made with clay based on our 2D radiographic images. After taking X-rays of the 3D structure, it was compared whether it matches the structural image of the blind box. The educational effect for the practical training surveyed class faithfulness, radiographic image interpretation ability (attenuation concept, contrast concept, windowing concept, 3-dimensional reading ability), class satisfaction (interest, external recommendation, immersion) on a 5-point Likert scale as an anonymous student self-writing method. As a result, all evaluation items had high positive effects without significant differences between males and females. Practical education using blind boxes is a meaningful example of radiology education technology using 3D printing technology, and it is expected to be used as content to improve students' problem-solving skills and increase satisfaction with major subjects.

• Journal of Radiation Protection and Research
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• v.26 no.4
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• pp.357-365
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• 2001

Intervention levels for protection of the public in a radiological emergency are theoretically derived by the cost-benefit approach with the concept of justification and optimization. Intervention levels on the sheltering, evacuation, temporary relocation and permanent resettlement for protection of the public are estimated with the cost to protective countermeasures and the value from dose averted which are the site specific parameters. As a result, it is confirmed that IAEA guidelines for intervention levels are applicable to the radiological emergency in Korea. Optimum ranges of 5 - 10 mSv/2days for sheltering, 25 - 130 mSv/week for evacuation, 15 - 90 mSv/month lot temporary relocation and 600 - 3,500 mSv/lifetime for permanent resettlement for intervention levels are also provided. The result can be applied as useful data to update intervention levels under the theoretical background in Korea.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2017.10a
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• pp.470-472
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• 2017

Currently, various studies using chemotherapy, such as surgical treatment, radiation or optical therapy, and chemotherapy, are underway. In addition, expensive chemotherapeutic drugs and large-scale equipment have been developed to improve the accuracy and therapeutic effect. However many side effects caused by misuse of the kind of light source, radiation, and cancer treatment have been observed. Therefore, in this paper, we propose a novel chemotherapeutic method by developing a customized cancer cell proliferation inhibition module based on a microcontroller that is relatively inexpensive, easy to operate, and able to operate in various wavelength light sources.

• Applied Biological Chemistry
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• v.50 no.3
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• pp.217-223
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• 2007

Cosmetic products including toner and essence were manufactured to evaluate the effect of green tea polyphenols. In addition, irradiation was applied to remove an undesirable color of green tea polyphenol(GTP), which may cause a problem in marketing. The growth inhibition rates of GTP, PT, and PE on all cell lines were shown to be over 80% at 500 ppm concentration. Especially the growth inhibition rates of GTP, PT, and PE on human melanoma(G361) cells were shown to be over 80% at only 100 ppm concentration. Results indicate that the addition of irradiated green tea polyphenol may be effective in the manufacturing of functional cosmetics including toner and essence with various anti-cancer activities.

• Radiation Oncology Journal
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• v.9 no.1
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• pp.7-15
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• 1991

Pentoxifylline (PENTO) has been known to improve RBC fluidity, and thus improve the flux of RBC through narrow capillaries. Additionally, PENTO also decreases the $O_2$ affinity of hemoglobin by increasing 2,3-DPG levels, thereby increasing the $O_2$ release from RBC. Nicotinamide (NA) has been reported to decrease the number of acutely hypoxic cells in tumors by temporarily increasing tumor blood flow. Therefore, the purpose of this study was to examine whether the combination of PENTO and NA (PENTO+NA) would reduce the radioresistance of the Fsall murine fibrosarcoma by oxygenating the hypoxic cells. We obsewed a significantly enhanced radiation-induced growth delay of the FSaII tumors by PENTO+NA. Thus the enhancement ratio was between 2.5 and 2.8 in growth delay assay. The $TCD_{50}$ of control tumors was about 57 Gy, but that of PENTO+NA treated tumors was about 32Gy. Thus $TCD_{50}$ was modified by a factor of 1.8. We also observed that PENTO+NA exerted no effect on the radiation-induced skin damage after the legs without bearing tumors were exposed to X-irradiation. In order to clarify radiosensitizing effects of PENTO+ NA, changes in tumor blood flow and intratumor pOf were measured using laser Doppler flowmetry and $O_2$ microelectrode methods. The tumor blood flow significantly increased at 10 min. after injection of PENTO+ NA. Furthermore, we also found that PENTO+ NA significantly increased intratumor $pO_2$ from 8 to 19 mmHg. We concluded that PENTO+MA was far more effective than NA alone or PENTO alone. The increase in the response of tumors in vivo to X-irradiation appeared to be due mainly to an increase in the tumor oxygenation. Further studies using various concentrations of PENTO alone and in combination with NA to obtain better sequencing and maximal radiosensitization are warranted.

• Radiation Oncology Journal
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• v.9 no.1
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• pp.81-85
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• 1991

The differentiation between post-radiotherapy lung fibrosis and tumor recurrence is often a dilemma to physicians. Twenty two patients with lung cancer who had received 45~60 Gy to the chest were chosen to study the possible role of gallium-67 scan. Seventeen squamous cell carcinomas were treated with only radiotherapy, 3 small cell carcinomas with combination chemotherapy, 2 adenocarcinomas with lobectomy. A total of 8 patients with pneumonitis with or without fibrosis and recurrence showed uptake of gallium at the site of inflammation. Of the 12 recurrences and residual diseases after radiotherapy, positive gallium uptake was present in 11 cases (92%). Of the 10 recurrence-free cases, all the 5 patients with pneumonitis revealed gallium accumulation. However, 4 of the 5 patients (80%) with recurrence-free fibrosis have not accumulated gallium in the fibrotic areas. Fibroses in S patients were developed after 8 months of completion of radiotherapy. These facts suggest that gallium-67 scan after 1 year post-treatment may aid for the discrimination of fibrosis from tumor recurrence unless pneumonitis is present.

• Journal of Radiation Protection and Research
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• v.20 no.2
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• pp.117-122
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• 1995

Meteorological Data Acquisition System (MDAS) and Meteorolocical Information Processing System (MIPS) have been developed for the measurement of the meteorological parameters at the Korea Atomic Energy Research Institute site. MIPS represents the measured meteorological data graphically on a computer screen. MDAS and MIPS are interfaced with real-time radiological dose assessment system (FADAS), which has been developed to rapidly assess the radiological consequences and to support decision-making under radiological emergencies.

• Radiation Oncology Journal
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• v.9 no.2
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• pp.253-263
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• 1991

Twenty-seven patients with unresectable extrahepatic bile duct carcinoma (n=21) or with microscopic evidence of tumor rest after aggressive surgery for extrahepatic bile duct carcinoma (n=6) between 1985 and 1990 were given radiotherapy consisting intentionally external radiotherapy and/or intraluminal therapy using Gamma-Med 12i (192-Ir) high dose rate (HDR) remote control afterloading system following bile drainage procedures and Gianturco stent insertion. The objectives of this study has been to assess the feasibility and effects on survival of a combination of external radiotherapy and brachytherapy with which we hope to achieve optimal loco-regional control for patients with unresectable extrahepatic bile duct tumors. Sixteen patients were men and eleven were women, and the mean age was 58 years (34-70). 10MV X-ray was used for radiation therapy, with the total dose ranging from 45 Gy to 55 Gy, and intraluminal brachytherapy performed after external radiotherapy, with the dose of total 15 Gy. The minimum follow up was 12 months. Failure were predominantly local-regional, without distant failure. Median survival was 10 months; 2-year actuarial survival rates was $21\%$. Median survival for common hepatic duct (CHD) cancer was 9 months; for common bile duct (CBD) cancer, was 16 months. And median survival for incomplete surgery/external radiotherapy group and external/intraluminal radiotherapy group was 10 months; for external radiotherapy alone group, was 6 months. Use of chemotherapy and/or hyperthermia were not affected in survival. Therefore, our result is that the survival rates in the group of external/intraluminal radiotherapy were comparable with ones in the group of incomplete resection/external radiotherapy, and so we believe that the aggressive local and regional radiotherapy can improve the quality of life and the survival length.

• Journal of the Korean Society of Radiology
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• v.11 no.5
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• pp.413-421
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• 2017

Mammography, the basic test for finding and treating increased breast cancer, gives the anxiety of cancer and radiation exposure to most women. In addition, it gave very severe compression pain, so we studied the degree of pain and tried to reduce the pain. The purpose of this study is to compare and analyze the modified imaging technique and the basic imaging technique based on clinical experience, respectively. The subjects of this study were 160 women from 30 to 60 years old who visited to Seoul Boramae Hospital operated by Seoul National University Hospital from February to March 2017 for breast screening. Modified 80 persons and 80 persons were divided into two groups, and each group was asked to fill out questionnaires sequentially without knowing the subjects. The first method is a modified method in which an automatic pedal is divided into four or more presses, a manual pressure is used together, and an attitude is described in detail. Secondly, we used only the automatic pedal compression method and press it within 1-3 times. In the mean of the pain distribution, the experimental group (modified method) was 2.49 and the control group (basic method) had an average of 4.86, which showed 48.8% less pain. In this modified method, the pain scores of the experimental group were lower than those of the control group, and the degree of the pain was statistically significant.

• Proceedings of the Korean Environmental Sciences Society Conference
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• 2003.05a
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• pp.407-408
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• 2003

다중입력조건에 따른 단일 출력퍼지시스템인 인구밀도와 도로조건에 따른 소개속도의 모델링시스템에서는 인구밀도와 도로조건의 퍼지멤버쉽에 대한 소개속도의 상승작용을 확인할 수 있었다. 그러나 도로조건을 평가하는 방법을 포장과 비포장으로만 구분함으로 인해 발생하는 퍼지추론과정에서 비탄력성은 향후 도로조건에 대한 세밀한 조사를 통하여 퍼지멤버쉽함수의 형태를 재고해야 할 것으로 판단된다. 실제 원자력시설에서 발생할 수 있는 사고의 경우 방사능에 노출될 수 있는 일반대중은 방사능에 대한 깊은 지식을 가지지 못하는 경우가 대부분이다. 따라서 차폐효과 혹은 소개속도를 정량적으로 파악하기 힘든 경우가 많다. 따라서, 이러한 퍼지시스템은 방사선 비상대응 시스템을 개발하는 의사결정자나 비상시 방사능에 노출되는 사람들의 대응 방식을 모델링하는데 유용할 것으로 판단된다.