• Journal of the Korean Society of Food Science and Nutrition
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• v.44 no.11
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• pp.1629-1636
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• 2015

The edible mushroom Agaricus blazei Murill is known to have many physiological functions, including antitumor, antiviral, and anti-inflammatory effects. Aqueous extracts were obtained by extracting A. blazei in water at $90^{\circ}C$ for 15 h, followed by spray-drying with dextran at a 70:30 ratio. In this study, we examined the immunomodulatory effect of A. blazei Murill water extract (ABM) in BALB/c mice. Mice were administered orally with 4, 20, and 100 mg/kg of ABM for 21 days. ABM-treated mice did not show significant differences in body and organ weights compare to saline-treated control mice. Splenocytes isolated from ABM-administered mice revealed similar levels of cellularity and proliferation compared to control mice, whereas they showed increased natural killer (NK) cell activity and decreased IL-4 and IL-12 production. Different from in vivo results, splenocytes isolated from normal mice showed increased proliferation and $INF-{\gamma}$ production following ABM treatment in vitro. In addition, ABM treatment enhanced macrophage proliferation and nitric oxide (NO) production in a dose-dependent manner. However, ABM had no effect on LPS-induced NO production. These results suggest that A. blazei modulates immune function by increasing NK cell activity and macrophage function.

• Korean Journal of Plant Taxonomy
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• v.41 no.4
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• pp.299-314
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• 2011

The choice of molecular markers is the first step when selecting experimental plans in the field of population genetics. The popular molecular markers in population genetic studies are mainly allozyme, RAPD, RFLP, AFLP, microsatellite, SNP and ISSR. Among these, microsatellites are frequently found in nuclear, chloroplast and mitochondrial genome, showing a high level of polymorphism and nuclear microsatellites are codominant. Thus, it is a favorable molecular marker for population structure analyses and genetic diversity studies. Microsatellites are composed of tandem repeated 1~6 base pair nucleotide motifs and can be easily amplified by PCR reactions using locus specific primers. Because microsatellites have low cross-species transferability, however, they are only applicable between phylogenetically close species. In wild plants, the lack of genomic information and the high development cost of the microsatellite obstruct the wider use of microsatellites in plant population genetics research. In this review, we introduce the basis for microsatellite markers, the development process, and analytical methods as well as evolutionary models and their applications. In addition, possible genotyping errors which lead to erroneous conclusions are discussed.

• Journal of the Korea Concrete Institute
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• v.29 no.1
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• pp.101-107
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• 2017

This study aimed to conduct the basic analysis on the fractal characteristics of cementitious materials. The pore structure of cement paste incorporating ground granulated blast furnace slag (GGBFS) was measured using mercury intrusion porosimetry (MIP) and the fractal characteristics were investigated using different models. Because the pore structure of GGBFS-blended cement paste is an irregular system in the various range from nanometer to millimeter, the characteristics of pore region in the different scale may not be adequately described when the fractal dimension was calculated over the whole scale range. While Zhang and Li model enabled analyzing the fraction dimension of pore structure over the three divided scale ranges of micro, small capillary and macro regions, Ji el al. model refined analysis on the fractal characteristics of micro pore region consisting of micro I region corresponding to gel pores and micro II region corresponding to small capillary pores. As the pore size decreased, both models suggested that the pore surface of micro region became more irregular than macro region and the complexity of pores increased.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.34 no.3
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• pp.317-324
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• 2010

Metal-supported solid oxide fuel cells (SOFCs) have been developed to commercialize SOFCs. This new type of SOFC has high mechanical strength, but its mass transfer rate may be low due to the presence of a contact layer. In this study, the mass transfer characteristics of an anode-supported SOFC and a metal-supported SOFC are studied by performing numerical simulation. Governing equations, electrochemical reactions, and ceramic physical-property models are determined simultaneously; molecular diffusion and Knudsen diffusion are considered in mass transport analysis of porous media. The experimental results are compared with simulation data to validate the results of numerical simulation. The average current density of the metal-supported SOFC is 23% lower than that of the anode-supported SOFC. However, because of the presence of the contact layer, the metal-supported SOFC has a more uniform distribution than the anode-supported SOFC.

• Transactions of the KSME C: Technology and Education
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• v.3 no.1
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• pp.23-28
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• 2015

In this paper, we performed the design optimization dual-shell and tube heat exchanger on exhaust waste heat recovery for gas heat pump using CFD and RSM. CFD analysis is useful to design the complex structure such as double shell and tube heat exchanger. By computer simulation, engineers can assess the feasibility of the given design factors and change them to get a better design. But if one wishes to perform complex analysis on the simulation, such dual-shell and tube heat exchanger for GHP, the computational time can become overwhelming. CFD is powerful but it takes a lot of time for complex structure. Therefore, the CFD analysis is minimized by the optimization using the RSM method. As a result, the number of baffle and tube are optimized by 6 baffles and 25 tubes for heat transfer and flow friction. And then pressure drop and heat transfer is improved about 12.2%. We confirm the design optimization using CFD and RSM is useful on complex structure of heat exchanger.

• Korean Journal of Environment and Ecology
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• v.25 no.4
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• pp.590-600
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• 2011

The research was carried out for prediction of the potential habitats of warm-temperate evergreen broad-leaved trees under the current climate(1961~1990) and three climate change scenario(2081~2100) (CCCMA-A2, CSIRO-A2 and HADCM3-A2) using classification tree(CT) model. Presence/absence records of warm-temperate evergreen broad-leaved trees were extracted from actual distribution data as response variables, and four climatic variables (warmth index, WI; minimum temperature of the coldest month, TMC; summer precipitation, PRS; and winter precipitation, PRW) were used as predictor variables. Potential habitats(PH) was predicted 28,230$km^2$ under the current climate and 77,140~89,285$km^2$ under the three climate change scenarios. The PH masked by land use(PHLU) was predicted 8,274$km^2$ and the proportion of PHLU within PH was 29.3% under the current climate. The PH masked by land use(PHLU) was predicted 35,177~45,170$km^2$ and increased 26.9~36.9% under the three climate change scenarios. The expansion of warm-temperate evergreen broad-leaved trees by climate change progressed habitat fragmentation by restriction of land use. The habitats increase of warm-temperate evergreen broad-leaved trees had been expected competitive with warm-temperate deciduous broadleaf forest and suggested the expand and northward shift of warm-temperate evergreen broad-leaved forest zone.

• Journal of the Institute of Electronics and Information Engineers
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• v.51 no.7
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• pp.18-25
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• 2014

To increase wireless capacity, the concurrent use of multiple wireless interfaces on different frequency bands, called aggregation, can be considered. In this paper, we focus on aggregation of multiple Wi-Fi interfaces with packet-level traffic spreading between the interfaces. Two aggregation schemes, link bonding and multipath TCP (MPTCP), are tested and compared in a dualband Wi-Fi radio system with their Linux implementation. Various test conditions such as traffic types, network delay, locations, interface failures and configuration parameters are considered. Experimental results show that aggregation increases throughput performance significantly over the use of a single interface. Link bonding achieves lower throughput than MPTCP due to duplicate TCP acknowledgements (ACKs) resulting from packet reordering and filtering such duplicate ACKs out is considered as a possible solution. However, link bonding is fast responsive to links' status changes such as a link failure. It is shown that different combinations of interface weights for packet spread in link bonding result in different throughput performance, envisioning a spatio-temporal adaptation of the weights. We also develop a mathematical model of power consumption and compare the power efficiency of the schemes applying different power consumption profiles.

• Journal of Digital Contents Society
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• v.4 no.2
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• pp.167-179
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• 2003

It has been widely researched in many studies what is the most effective way to learn English as a second language. It has been generally accepted that the most effective teaching method is to make students interested in learning of English. Teaching method has to be modified with the change of the times according to the demand of the students. The purpose of this study is to reveal that language teaming method through internet could be more effective than that of the existing teaching one by offline loaming. For this purpose some subject students were divided by two groups of the experimental and of the controlled. From the result of the study it could be derived that teaching method, by means of cyber lecture, make a great effect not only on the attitude but on the achievement of the students when they are in the class of English as a second language. This paper also shows what could be the typical model for the teaching method by internet based on the experiment. This kind of way of teaching is supported by the questionnaire which has much more positive response from the students who were in the member of experimental group. Finally such a experiment would be described based on the Web-oriented teaching method with the respect of education of digital contents.

• Journal of Korea Port Economic Association
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• v.25 no.1
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• pp.223-248
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• 2009

The purpose of this empirical study is to examine and explore the relationships between three variables; shipping companies' service quality, customer satisfaction and customer loyalty. Special features of this study could be summarized as following. First, this is empirical study based on market research according to the definition of 'customer' as freight forwarders and actual exporter/importer together contrary to previous studies. Second, to evaluate shipping companies' service quality, 5 components of SERVPERF model was used. Third, to test correlations between 3 variables; service quality, customer satisfactions and customer loyalty, statistical analysis was used with tools of SPSSWIN ver 15.0 and AMOS ver 7.0. For effective study, many thesis have been obtained through literature survey. However, major results were compiled from directly structured questionnaire, which were collected from Korean import/ export companies and freight forwarders.

• Food Science and Preservation
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• v.22 no.1
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• pp.1-11
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• 2015

Raspberries are a good resource of polyphenols and have a powerful antioxidant activity, but shelf life for raspberries is short which brings a lot of economic losses. In this study, we try to use cool-air ($20{\sim}40^{\circ}C$) or hot-air ($60{\sim}100^{\circ}C$) to produce semi-dried raspberries with extended shelf life, and to determine the best method for improving fruit quality by minimizing nutrient losses during drying processes. The effects of process variables (drying temperature and processing time) on the quality of final dried raspberries were investigated. Response surface methodology was employed to establish statistical models for simulating the drying processes, and the moisture residue content and the loss ratios of total phenolic content (TPC), vitamin C (VC), and ellagic acid (EA) that result from the drying processes of raspberries using either hot or cool-air were predicted. Superimposed contour plots have been successfully used in the determination of the optimum zone within the experimental region. Optimal conditions determined for achieving minimal losses of TPC, VC, and EA, and a final moisture residue of 45% using the hot-air drying process were a drying temperature of $65.75^{\circ}C$ and a processing time of 4.3 hr. While for the cool-air process, the optimal conditions predicted were $21.3^{\circ}C$ and 28.2 hr. Successful application of response surface methodology provided scientific reference for optimal conditions of semi-drying raspberries, minimizing nutrient losses and improving product quality.