• Title/Summary/Keyword: 반복측정 안정성

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Dopamine determination using a biosensor based on multiwall carbon nanotubes paste and burley tobacco-peroxidase (담배 잎-peroxidase와 다중벽 탄소 나노튜브를 이용한 dopamine의 정량)

  • Kwon, Hyoshik;Jeon, Byong-Suk;Pak, Yongnam
    • Analytical Science and Technology
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    • v.28 no.2
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    • pp.98-105
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    • 2015
  • The development of an enzymatic biosensor for dopamine determination based on multiwall carbon nanotubes (MWCNTs) and peroxidase obtained from the crude extract of burley tobacco (Nicotiana tabacum L.) was proposed. Peroxidase catalyzes the oxidation of dopamine to dopamine quinone. The influence on the response of analytical parameters of biosensors such as enzyme concentration, dopamine concentration, pH, and phosphate buffer solution concentration were investigated. The analytical parameters obtained, including sensitivity, linearity, and stability, were investigated. The proposed method for dopamine determination presented good selectivity even in the presence of uric acid and ascorbic acid. The sensor presented a higher response for dopamine in 0.010 M phosphate buffer at pH 6.50, with an applied potential of -0.15 V. The detection limit of the electrode was 2.7×10−6 M (S/N = 3) and the relative standard deviation of the measurements, which were repeated 10 times using 5.0×10−2 M dopamine, was 1.3%.

Evaluation of Dynamic Soil Properties Using Dynamic Tests (동적시험에 의한 동적지반특성 평가)

  • Lee, Myung Jae;Shin, Jong Ho;Kang, Ki Young;Chon, Chun Su
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.10 no.2
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    • pp.91-102
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    • 1990
  • The representative tests in this study are performed at a selected site which has the soil layers to analyze the safety and economy of the dynamic analysis for the variable soil conditions. Crosshole test and downhole test of small strain level tests and triaxial test of large strain level test are performed in the soil layers, and in the rock layers, crosshole test and downhole in-situ tests and laboratory sonic test are performed to measure the dynamic shear modulus, damping ratio, and Poisson$\acute{s}$ ratio of the soil and the rock. The correlations between the dynamic soil properties from the tests and the basic soil properties are determined through the regression analysis. The representative design value of the soil is determined by probability analysis of the test results. It is determined from the nonlinear stress-strain model in soils, and the value at small strain level is computed in rocks according to the distribution of the type of soils and the affecting variables. The constitutive value is systematized to be utilized in the analysis of the test results, and computation of the input soil data.

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Development of a Portable and Disposable pH Sensor Based on Titanium Wire with High Electrochemical Sensing Performance (우수한 전기화학적 센싱 성능을 지닌 티타늄 와이어 기반의 휴대 및 일회용 pH 센서 개발)

  • Yoon, Eun Seop;Yoon, Jo Hee;Son, Seon Gyu;Kim, Seo Jin;Choi, Bong Gill
    • Applied Chemistry for Engineering
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    • v.32 no.6
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    • pp.700-705
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    • 2021
  • A portable and disposable pH sensor based on Ti wire was successfully developed for monitoring hydronium ion concentrations. A sensing electrode was prepared by electrochemically depositing iridium oxide onto a Ti wire, while a reference electrode was fabricated by coating Ag/AgCl ink on a Ti wire. Combining the two electrodes in the pH sensor enabled the collection of open circuit potential signals when the sensor was immersed in solutions of various pH values. The pH sensor exhibited excellent electrochemical sensing performance in terms of sensitivity, response time, repeatability, selectivity, and stability. To demonstrate point-of-measurement applications, the pH sensor was integrated with a wireless electronic module that could communicate with a mobile application. The portable pH sensor accurately measured pH changes in real samples. The results obtained were consistent with those of using a commercial pH meter.

A Study on the Improvement of Performance Testing System of Domestic Surveying Equipment (국내 측량장비 성능검사제도 개선방안 연구)

  • MIN, Kwan-Sik
    • Journal of the Korean Association of Geographic Information Studies
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    • v.19 no.1
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    • pp.53-63
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    • 2016
  • In this paper, we proposed the improvements for performance test and surveying equipment regulations, standards, methods and procedures, depending on the need of improving the legal system for surveying equipment in a diverse and sophisticated surveying industry. This research was performed first investigating the existing legal systems(Act on the establishment and management of spatial data, Framework act on national standards, ISO 17123, JIS B 7912) with respect to the surveying equipment performance testing and the research for IOS and KOLAS suggested the improvements on the application for the surveying equipment performance testing standard. More exactly, first, two years were presented for the surveying equipment performance testing cycle considering the precise accuracy of the instrument stability, purpose and frequency of use, etc. Second, the abolition of the measurement distance by grade and the upward or cross-grade adjustment of the single prism standards about the light wave rangefinder and total station were suggested for the improvement on survey equipment performance criteria. Third, since the main function of total station is focused on a three-dimensional coordinate measurement due to the improvement of surveying equipment performance testing, it was proposed to use the precision(repeatability) of the coordinate measuring method as an evaluation method.

Surface Dose Evaluation According to the Environment Around the Patient after Nuclear Medicine Examination (핵의학 검사 후 환자의 주위 환경에 따른 표면 선량 평가)

  • Lee, Young-Hee;Park, Jae-Yoon
    • Journal of the Korean Society of Radiology
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    • v.15 no.7
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    • pp.943-948
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    • 2021
  • The purpose of this study was to investigate changes in surface dose due to increased scattering of gamma rays from patients injected with 99mTc and 18F, which are radioactive isotopes, in close contact with materials with high atomic number such as the walls of the stable room. Prepare 99mTc and 18F by injecting 20 and 10 mCi respectively into the NEMA phantom, and then measuring the surface dose for 60 minutes by positioning the phantom at a height of 1 m above the surface, at a distance of 0, 5 and 10 cm from the wall, and at the same location as the phantom facing the wall. Each experiment was repeated five times for reproducibility of the experiment and one way analysis of variability (ANOVA) was performed for significance testing and Tukey was used as a post-test. The study found that surface doses of 220.268, 287.121, 243.957, and 226.272 mGy were measured at 99mTc, respectively, in the case of empty space and in the case of 0, 5 and 10 cm, while those of 18F were measured at 637.111, 724.469, 657.107, and 640.365 mGy, respectively. In order to reduce changes in surface dose depending on the patient's location while waiting, it is necessary to keep the distance from the ground or the wall where the patient is closely adhered to, or install an air mattress, etc., to prevent the scattered lines as much as possible, considering the scattered lines due to the wall etc. in future setup of the patient waiting room and safety room, and in addition to the examination, the external skin width may be reduced.

Detorque values of abutment screws in a multiple implant-supported prosthesis (다수 임플란트 지지 보철물에서 지대주 나사의 풀림 토크값에 대한 연구)

  • Lee, Ju-Ri;Lee, Dong-Hwan;Hwang, Jae-Woong;Choi, Jung-Han
    • The Journal of Korean Academy of Prosthodontics
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    • v.48 no.4
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    • pp.280-286
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    • 2010
  • Purpose: This study evaluated the detorque values of screws in a multiple implant-supported superstructure using stone casts made with 2 different impression techniques. Material and methods: A fully edentulous mandibular master model and a metal framework directly connected to four implants (Br${\aa}$nemark $System^{(R)}$; Nobel Biocare AB) with a passive fit to each other were fabricated. Six experimental stone casts (Group 1) were made with 6 non-splinted impressions on a master cast and another 6 experimental casts (Group 2) were made with 6 acrylic resin splinted impressions. The detorque values of screws ($TorqTite^{(R)}$ GoldAdapt Abutment Screw; Nobel Biocare AB) were measured twice after the metal framework was fastened onto each experimental stone cast with 20 Ncm torque. Detorque values were analyzed using the mixed model with the fixed effect of screw and reading and the random effect of model for the repeated measured data at a .05 level of ignificance. Results: The mean detorque values were 7.9 Ncm (Group 1) and 8.1 Ncm (Group 2), and the mean of minimum detorque values were 6.1 Ncm (Group 1) and 6.5 Ncm (Group 2). No statistically significant differences between 2 groups were found and no statistically significant differences among 4 screws were found for detorque values. No statistically significant differences between 2 groups were also found for minimum detorque values. Conclusion: In a multiple external hexagon implant-supported prosthesis, no significant differences between 2 groups were found for detorque values and for minimum detorque values. There seems to be no significant differences in screw joint stability between 2 stone cast groups made with 2 different impression techniques.

Influence of Tightening Torque on Implant-Abutment Screw Joint Stability (조임회전력이 임플랜트-지대주 나사 연결부의 안정성에 미치는 영향)

  • Shin, Hyon-Mo;Jeong, Chang-Mo;Jeon, Yonung-Chan;Yun, Mi-Jeong;Yoon, Ji-Hoon
    • The Journal of Korean Academy of Prosthodontics
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    • v.46 no.4
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    • pp.396-408
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    • 2008
  • Statement of problem: Within the elastic limit of the screw, the greater the preload, the tighter and more secure the screw joint. However, additional tensile forces can incur plastic deformation of the abutment screw when functional loads are superimposed on preload stresses, and they can elicit the loosening or fracture of the abutment screw. Therefore, it is necessary to find the optimum preload that will maximize fatigue life and simultaneously offer a reasonable degree of protection against loosening. Another critical factor in addition to the applied torque which can affect the amount of preload is the joint connection type between implant and abutment. Purpose: The purpose of this study was to evaluate the influence of tightening torque on the implant-abutment screw joint stability. Material and methods: Respectively, three different amount of tightening torque (20, 30, and 40 Ncm) were applied to implant systems with three different joint connections, one external butt joint and two internal cones. The initial removal torque value and the postload (cyclic loading up to 100,000 cycles) removal torque value of the abutment screw were measured with digital torque gauge. Then rate of the initial and the postload removal torque loss were calculated for the comparison of the effect of tightening torques and joint connection types between implant and abutment on the joint stability. Results and conclusion: 1. Increase in tightening torque value resulted in significant increase in initial and postload removal torque value in all implant systems (P < .05). 2. Initial removal torque loss rates in SS II system were not significantly different when three different tightening torque values were applied (P > .05), however GS II and US II systems exhibited significantly lower loss rates with 40 Ncm torque value than with 20 Ncm (P < .05). 3. In all implant systems, postload removal torque loss rates were lowest when the torque value of 30 Ncm was applied (P < .05). 4. Postload removal torque loss rates tended to increase in order of SS II, GS II and US II system. 5. There was no correlation between initial removal torque value and postload removal torque loss rate (P > .05).

Effect of Moisture on the Melting Point and High-Temperature Stability of NaKZn-Chloride (수분이 NaKZn-Chloride의 녹는점과 고온안정성에 미치는 영향)

  • Lee, Jeong Hwan;Kim, Young;Yoon, Seok Ho;Lee, Kong Hoon;Choi, Jun Seok
    • Korean Chemical Engineering Research
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    • v.56 no.4
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    • pp.555-560
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    • 2018
  • The high temperature stability of a chloride mixture, $NaCl-KCl-ZnCl_2$ (NaKZn-Chloride), is investigated to evaluate its potential as a thermal storage material. A thermal storage media should maintain a stable thermal properties within the temperature range of heat storage. Results from an a priori experiment showed that the NaKZn-chloride is stable only up the much lower temperature, while its stability limit is reported to be $850^{\circ}C$ in the literature. This study aims to investigate if the thermal property is changed by the moisture absorbed in the heat storage material. The effect of moisture content on the thermal properties was measured. The results show that the melting point remains the same regardless of the amount of moisture absorbed. Meanwhile, the high temperature stability is lower for the moisture treated samples. The results of this work infer that the loss of a hygroscopic thermal storage media can be reduced by avoiding its contacts to moisture in designing high temperature thermal storage systems.

Development of Fracture Toughness Evaluation Method for Composite Materials by Non-Destructive Testing Method (비파괴검사법을 이용한 복합재료의 파괴인성 평가법 개발)

  • Lee, Y.T.;Kim, K.S.
    • Journal of the Korean Society for Nondestructive Testing
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    • v.18 no.4
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    • pp.278-291
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    • 1998
  • Fracture process of continuous fiber reinforced composites is very complex because various fracture mechanisms such as matrix cracking, debonding, delamination and fiber breaking occur simultaneously during crack growth. If fibers cause crack bridging during crack growth, the stable crack growth and unstable crack growth appear repeatedly. Therefore, it is very difficult to exactly determine tile starting point of crack growth and the fracture toughness at the critical crack length in composites. In this research, fracture toughness test for CFRP was accomplished by using acoustic emission(AE) and recording of tile fracture process in real time by video-microscope. The starting point of crack growth, pop-in point and the point of unstable crack growth can be exactly determined. Each fracture mechanism can be classified by analyzing the fracture process through AE and video-microscope. The more reliable method ior the fracture toughness measurement of composite materials was proposed by using the combination of R-curve method, AE and video microscope.

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Development of a Gene's Functional Classifying System for a Microarray Data using a Gene Ontology (유전자 온톨로지를 이용한 마이크로어레이 데이터의 유전자 기능 분석 시스템의 개발)

  • Lee, Jong-Keun;Park, S.S.;Hong, D.W.;Yoon, J.H.
    • Proceedings of the Korean Information Science Society Conference
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    • 2006.10c
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    • pp.246-251
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    • 2006
  • 마이크로어레이 실험은 수 천에서 수 만개의 유전자 발현 결과를 동시에 측정할 수 있어 질병의 발현 형질 분류 등에 유용하게 이용되고 있다. 그러나 마이크로어레이 실험은 동일한 플랫폼의 실험이라 할지라도 환경 등에 따라 그 실험 결과에 차이가 나는 등 오차를 항상 포함하고 있다. 또한 마이크로어레이 실험은 아직 고가의 실험으로 분류되어 다수의 샘플에 대한 반복 실험 결과를 얻기 어려운 상황이다. 따라서 이종의 플랫폼, 데이터 포맷, 정규화 기법 등이 서로 다른 데이터를 효율적으로 통합하여 유용한 정보를 추출하는 새로운 방식의 개발이 필요하다. 본 논문은 이와 같은 문제를 해결하기 위한 기초 단계 연구 결과이다. 마이크로어레이 실험 데이터로부터 통계적 방법을 이용하여 유의(informative) 유전자를 추출하고 유전자 온톨로지(Gene Ontology : GO)와의 연계를 통하여 유전자 정보의 기능적 분류 결과를 사용자에게 제공하는 유전자 기능 분석 시스템의 설계 및 구현 방안을 보인다. 본 시스템의 실험방법에서는 3-Fold Filtering 기법을 통하여 발현 차가 큰 유전자를 추출하고, t-검정 기법에 의하여 이들 유전자를 순위화 하였으며, 이 중 상위 100개의 유전자를 유의 유전자로 추출하였다. 다음, 이 들 유의 유전자의 t-검정 값을 GO의 유전자 기능을 나타내는 해당 텀 (term)에 가중치로 부과하여 각 유전자들과 기능적으로 연관성이 높은 텀들을 추출한다. 또한 본 연구의 유효성을 검증하기 위하여 본 시스템에 의한 마이크로어레이 데이터 분석 결과를 전문가에 의한 유전자 기능 분석 결과와 비교한다.투명성 있는 서비스를 제공하고 높은 신뢰성과 안정성이 확보될 수 있도록 구성하고자 한다. Query 수행을 여러 서버로 분산처리하게 함으로써 성능에 대한 신뢰성을 향상 시킬 수 있는 Load Balancing System을 제안한다.할 때 가장 효과적인 라우팅 프로토콜이라고 할 수 있다.iRNA 상의 의존관계를 분석할 수 있었다.수안보 등 지역에서 나타난다 이러한 이상대 주변에는 대개 온천이 발달되어 있었거나 새로 개발되어 있는 곳이다. 온천에 이용하고 있는 시추공의 자료는 배제하였으나 온천이응으로 직접적으로 영향을 받지 않은 시추공의 자료는 사용하였다 이러한 온천 주변 지역이라 하더라도 실제는 온천의 pumping 으로 인한 대류현상으로 주변 일대의 온도를 올려놓았기 때문에 비교적 높은 지열류량 값을 보인다. 한편 한반도 남동부 일대는 이번 추가된 자료에 의해 새로운 지열류량 분포 변화가 나타났다 강원 북부 오색온천지역 부근에서 높은 지열류량 분포를 보이며 또한 우리나라 대단층 중의 하나인 양산단층과 같은 방향으로 발달한 밀양단층, 모량단층, 동래단층 등 주변부로 NNE-SSW 방향의 지열류량 이상대가 발달한다. 이것으로 볼 때 지열류량은 지질구조와 무관하지 않음을 파악할 수 있다. 특히 이러한 단층대 주변은 지열수의 순환이 깊은 심도까지 가능하므로 이러한 대류현상으로 지표부근까지 높은 지온 전달이 되어 나타나는 것으로 판단된다.의 안정된 방사성표지효율을 보였다. $^{99m}Tc$-transferrin을 이용한 감염영상을 성공적으로 얻을 수 있었으며, $^{67}Ga$-citrate

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