• Journal of Life Science
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• v.32 no.3
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• pp.256-262
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• 2022

Oxysterols are oxygenated metabolites of cholesterol generated by serial enzymatic reactions during bile acid synthesis. Similar to cholesterol, oxysterols move rapidly to the intracellular region and modulate various cellular processes, such as immune cell responses, lipid metabolism, and cholesterol homeostasis. Different nuclear transcription factors, such as glucocorticoid, estrogen, and liver X receptors, can be modulated by oxysterols in multiple tissues. The most abundant oxysterol, 27-hydroxycholesterol (27-OHC), is a well-known selective modulator that can either activate or suppress estrogen receptor activity in a tissue-specific manner. The contribution of 27-OHC in atherosclerosis development is apparent because a large amount of it is found in atherosclerotic plaques, accelerating the transformation of macrophages into foam cells that uptake extracellular modified lipids. According to previous studies, however, there are opposing opinions about how 27-OHC affects lipid and cholesterol metabolism in metabolic organs, including the liver and adipose tissue. In particular, the effects of 27-OHC on lipid metabolism are entirely different between in vitro and in vivo conditions, suggesting that understanding the physiology of this oxysterol requires a sophisticated approach. This review summarizes the potential effects of 27-OHC in atherosclerosis and metabolic syndromes with a special discussion of its role in metabolic tissues.

• Journal of Teachers' Pension
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• v.2
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• pp.47-102
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• 2017

오늘날 대다수의 선진 국가들은 고령화 사회에 대비하여 자국의 노후소득보장 제도를 대대적으로 개혁해 오고 있다. 우리나라의 경우에서도 지난 2015년 사학연금제도의 개혁이 이러한 취지에 해당될 수 있을 것이다. 본 연구에서는 고령화 사회의 문제가 단순히 노인부양비용의 증가 그 자체가 아니라, 평균수명의 증가에도 불구하고 늘어나게 된 노후의 삶에 대한 시간적 배분이 근로와 여가에 걸쳐 균형적으로 이루어지지 않고, 사회적 부양을 필요로 하는 노후의 여가만 일방적으로 늘어나고 있다는 점을 문제점으로 지적하였다. 따라서 이러한 차원에서 볼 때 고령화 사회의 문제는 생애근로기간의 연장을 통해서만 효과적으로 극복할 수 있을 것으로 생각된다, 하지만 이와는 반대로 개인별로 건강상태나 가족상황 등의 이유로 생애근로주기의 연장이 불가능한 사람들을 위하여 별도의 제도적 장치가 추가적으로 마련되어야 할 것이다. 종합해 보면, 고령화 사회의 노동시장 문제는 개인별로 다양한 욕구나 능력을 반영하여 각자에게 다양한 선택권을 보장해 줄 수 있는 방향으로 개선되어야 할 필요가 있다. 본 연구에서는 고령화 사회에 대비하여 연금수급연령 상향조정의 필요성을 사학연금제도를 중심으로 살펴보고, 대신 그로 인해 발생할 수 있는 소득공백문제와 연금가입경력 공백문제 등 제반의 충격을 흡수할 수 있는 제도적 장치로서 점진적 퇴직제도의 도입방안을 제안하였다. 개략적으로 사학연금제도에 있어서 점진적 퇴직모형은 법정연금수급연령의 인상 일정에 따라 다음과 같이 운영하는 방안을 제안하였다. 먼저 법정연금수급연령이 60세로 유지되는 2022년까지의 단기적 대책으로서 여기서 점진적 퇴직의 자격연령은 모든 가입자에게 60세로 적용하도록 한다. 이 경우 가입자들의 신분구분에 따라 각각 교수 5년, 교원 2년(문제해결에 대한 정책적 의지에 따라 이행구간을 확장할 수도 있음) 그리고 교직원 0년의 조기의 점진적 퇴직이 허용되므로, 현재 교원이나 교수의 임용대란문제에 효과적으로 대응을 할 수 있는 장점이 있다. 다음으로는 2023년 이후 2033년 사이 법정연금수급연령의 인상단계에 해당되는 기간 동안의 대책으로서 여기서는 교수, 교원, 교직원에게 적용되는 정년연령과 매년도 법정연금수급연령 사이의 기간을 조기의 점진적 퇴직 이행구간으로 정하도록 한다. 그리고 이러한 이행구간에 상당하는 기간만큼 후기의 점진적 퇴직 이행구간을 별도로 설정하여 그에 적절한 혜택이 주어질 수 있도록 한다. 마지막으로 2033년 이후부터는 교수, 교사, 교직원의 신분구분 없이 모두에게 적용되는 사항으로서 65세를 기준으로 그 이전의 5년은 사학연금의 적용을 받는 조기의 점진적 퇴직 그리고 그 이후의 5년은 국민연금의 적용을 받는 후기의 점진적 퇴직이 이루어질 수 있도록 한다. 그리고 전체 10년의 점진적 퇴직 이행구간 동안 개인별로 퇴직시점이나 퇴직형태의 선택이 자유롭게 이루어질 수 있도록 하기 위하여 보험수리의 원칙에 입각한 감액률 또는 가산율의 엄격한 적용을 제안하였다. 그리고 고령계층이 자신의 근로시간을 단계적으로 단축할 수 있도록 하고, 그 과정에서 발생하게 되는 소득의 감소부분은 별도의 제도적 방법(가교연금, 시간가치적립계정 등)으로 충당하도록 하는 방안을 제안하였다. 나아가 점진적 퇴직제도의 운영방식은 근로시간의 단축뿐만 아니라 작업부담의 경감 등에 대해서도 인정을 해주도록 해줌으로써 임금피크제도의 기능과 연계가 가능할 수 있도록 할 것을 제안하였다.

• Journal of Korea Entertainment Industry Association
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• v.13 no.8
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• pp.151-156
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• 2019

In recent years, the Korean realistic theme of the film momentum gradually rising. Realistic films do not stick to the business and market, and do not simply cater to the audience's needs for watching movies. They reflect social violence and cruel reality, allowing the audience to observe the structural contradictions in reality and think about the direction when watching movies. At the recent cannes film festival, "parasite" won the top prize palm in cannes by an overwhelming margin, with the highest score of 3.3 issues. Although this film is positioned as a thriller with comedy elements, it presents the opposite life images of Korean classes to the audience in a parasitic way, which not only expands the possibility and artistry of realistic film aesthetics, but also enhances the appreciation of the film and gives play to its own aesthetic value. Focusing on the technical and literary nature of the film, and having a high degree of attention to real life, it is an excellent work that tells about class opposition and thinking about reality. This paper considers and analyzes the content, form and creation method of parasite, and discusses the continuous exploration and attempt of realistic film to image language under the demand of market and system, evolving into new aesthetic expression.

• Journal of Ethics
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• no.75
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• pp.63-98
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• 2009

The Social Conflict Index in Korea is considerably high. In the situation where both parties' interests conflict each other, Korean society has shown immature democracy, which couldn't peacefully resolve the conflict because of the lack of tolerance against the counterparty's position. In terms of upbringing educated citizens, who could democratically communicate with others and approach problems, communication skill training is very important, reducing social costs by extreme conflict. Thus, this paper studied the necessity of communication skills training and its sociopolitical implication through case studies about "Communication and Negotiation" class, which is proceeded under university liberal education. Under current university curriculums, increased liberal education programs, related with speaking, focus on cultivating logical and critical thinking in the main. Based on these thinking skills, "Communication and Negotiation" has important implication in terms of cultivating mindset which resolves conflicts and considers other's position by collaborative and emotional perspectives. In terms of cultivating practical communication skills, this "Communication and Negotiation" class requires the change of teaching skills with various training programs, under students' active participation and feedback in the class exercise for resolving problems. Ultimately, through "Communication and Negotiation" class, and as members of society, students could learn matured citizenship and sense of responsibility by respecting others' position and reasonably resolving conflicts.

• Phonetics and Speech Sciences
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• v.15 no.3
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• pp.17-25
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• 2023

This study examines the fundamental frequency(f0) distribution of 2,740 Korean speakers in a dialogue speech corpus. Praat and R were used for the collection and analysis of acoustical f0 data after removing extreme values considering the interquartile f0 range of the intonational phrases produced by each individual speaker. Results showed that the average f0 value of all speakers was 185 Hz and the median value was 187 Hz. The f0 data showed a positively skewed distribution of 0.11, and the kurtosis was -0.09, which is close to the normal distribution. The pitch values of daily conversations varied in the range of 238 Hz. Further examination of the male and female groups showed distinct median f0 values: 114 Hz for males and 199 Hz for females. A t-test between the two groups yielded a significant difference. The skewness representing the distribution shape was 1.24 for the male group and 0.58 for the female group. The kurtosis was 5.21 and 3.88 for the male and female groups, and the male group values appeared leptokurtic. A regression analysis between the median f0 and age yielded a slope of 0.15 for the male group and -0.586 for the female group, which indicated a divergent relationship. In conclusion, a normative f0 distribution of different Korean age and sex groups can be examined in the conversational speech corpus recorded by a massive number of participants. However, more rigorous data might be required to define a relation between age and f0 values.

• Journal of agricultural medicine and community health
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• v.23 no.2
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• pp.157-174
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• 1998

A survey was conducted to study the influence of socia-demographic factors on health-related behaviors. from June 1 to July 31, 1996. The study population was 1,903 adults in Kyongju City. A questionnaire method was used to collect data. Health-related behaviors included 24 items for men and 26 items for women. The followings are summaries of findings : The compliance of health promotion activities was higher when the age was older in men, when married, when having no religion and when the education level was higher than the other groups. And it was significantly higher when the income was lower in men and higher in women, in the residents living in apartment, in white collar workers, in the chronic ill people and when the body weight was lower than the other groups. Notable differences were found in the composition of health behavior factors for socio-demographic characteristics. Men used more tobacco, coffee and tea, salt and alcohol than women. However, the practice rates of regular exercise and physical examination were higher in men than women. On the other hand, the practice rates of fruit/vegetable intake, milk drinking and regular tooth brushing were higher in women than men. When the age was old, the amount of fruit/vegetable intake, the frequency of physician visit and health check-up, and regularity of meal were increased. When the income was high, the use rate of seat-belts, the amount of coffee, milk, fruit/vegetable and red meat intake were increased. The frequency of regular exercise. tooth brushing, health check-up, pap test and breast self examination were higher in the rich than the poor. When the education level was high, the frequency of regular exercise and tooth brushing, and the use rate of seat belts were increased, and the amount of alcohol consumption and salt intake were decreased. These findings suggest that socio-demographic factors are significantly associated with the patterns of health behaviors. In conclusion public health programs and individual counseling efforts should be multifaceted and behavior-specific to encourage to practice healthy life-style.

• Korean Journal of Food Science and Technology
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• v.40 no.4
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• pp.430-435
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• 2008

The sensory characteristics of imported (two dry, two sweet, and one medium dry wines) and domestic (one sweet wine) red wine were evaluated by 250 panels. The preferences of aroma, color, sweetness, tartness, astringency, and overall acceptability were determined by 5-point just-about-right scale. Among six wines, B sample obtained the highest mean overall acceptability score of 3.67 and its chemical and sensory characteristics were as follow: cherry or strawberry aroma, 9.4 brix, 3.7% of sugar content, pH 3.5, 10% of ethanol, 0.14% of tannin, 5.74 mg/mL of total organic acids, and color of $L(12.04{\pm}0.01)$, $a(33.90{\pm}0.19)$, and $b(8.22{\pm}0.00)$. These results revealed that Korean consumers generally prefer sweet taste to dry one, flat taste to bitter one, and fruity aroma to others. Panels preferred a red wine containing high sugar content of $5{\sim}10%$. On the other hand, panels showed low preference to the wine containing tannin above 0.16%. However, these general trends were slightly varied depending on their ages and consuming frequencies.

• The korean journal of orthodontics
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• v.30 no.2 s.79
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• pp.143-157
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• 2000

To investigate the developmental stages of dental and skeletal maturation by ages and the correlations among dental maturity, skeletal maturity of cervical vertebrae, and that of hand-and-wrist, the author used the cephalograms, orthopantomograms, and hand-and-wrist radiograms of 1055 patients (male 458, female 597) aged 7 to 20 years old. In the cephalograms, the skeletal maturity stages of each bone were mainly assessed by Hassel and Farman's cervical vertebrae maturation indicators (CVMI) method. In the orthopantomograms, the dental maturity stages of each tooth were mainly assessed by Nolla's tooth calcification stages method. In the hand-and-wrist radiograms, the skeletal maturity stages of each bone were mainly assessed by Fishman's skeletal maturity indicators (SMI) method. The results were as follows. 1. There was a high correlation among dental maturity, skeletal maturity of cervical vertebrae, and that of hand-and-wrist in the both sexes (P<0.001). 2. There was a high correlation (r=0.91-0.93) between skeletal maturity of cervical vertebrae and that of hand-and-wrist. 3. There was a high correlation (r>0.8) between skeletal maturity of hand-and-wrist and maturity of upper and lower canine, first premolar, and second premolar. 4. There was high a correlation(r=0.8) between skeletal maturity of cervical vertebrae and maturity of upper canine. 5. By the ages, dental maturity, skeletal maturity of cervical vertebrae, and that of hand-and-wrist were obtained in the both sexes. In summary, dental maturity, skeletal maturity of cervical vertebrae, and that of hand-and-wrist we of sufficient diagnostic worth as an index to predict adolescent growth.

• Journal of the Korean Society of Clothing and Textiles
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• v.31 no.12
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• pp.1700-1709
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• 2007

The purpose of this study was to examine the relationships between thermo-physiological factors and the insensible loss of body weight(IL) of resting women wearing seasonal comfortable clothing. Air temperature was maintained at a mean of 22.5, 24.7, and 16.8 for spring/fall, summer and winter, respectively. We selected a total of 26 clothing ensembles(8 ensembles for spring/fall, 7 ensembles for summer, and 11 ensembles for winter). The results showed that 1) IL was $19{\pm}5g{\cdot}m^{-2}{\cdot}hr$ for spring/fall environment, $21{\pm}5g{\cdot}m^{-2}{\cdot}hr$ for summer, $18{\pm}6{\cdot}m^{-2}{\cdot}hr$ for winter(p<.001). 2) Insensible water loss through respiratory passage(IWR) showed the reverse tendency to IL. IWR was $6{\pm}1g{\cdot}m^{-2}{\cdot}hr$ for winter and $5{\pm}1g{\cdot}m^{-2}{\cdot}hr$ for summer. This difference was significant(p<.001). 3) The proportion of IWR out of whole insensible water loss(IW), had a mean of the mean 28% for summer and 38% for winter(p<.001). 4) In comfort, the heat loss by IW out of heat production had a mean of 25% for spring/fall, 27% for summer, and 23% for winter. 5) There was a weak negative correlation between It and clothing insulation/body surface area covered by clothing. 6) There were significant correlations between IL and air temperature$(T_a)$, air humidity$(H_a)$, energy metabolism, ventilation, mean skin temperature $\={T}_{sk})$ and clothing microclimate humidity$(H_{clo})$. However, the coefficients were less than 0.5. In conclusion, there were weak relationships between the IL and thermo-physiological factors. However, when subjects rested in thermal comfort, the IL was maintained in a narrow range even though the clothing insulation and air temperature were diverse.

• The korean journal of orthodontics
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• v.25 no.3 s.50
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• pp.355-373
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• 1995

Craniofacial region is a musculodentoskeletal system that consists of many anatomical structures ; cranioskeletal structures, dental arches, and formation and functions of masticatory muscles have close correlations. Growth and development of craniofacial region are influenced by not only hereditory factors, but also environmental factors such as craniofacial muscles and surrounding tissues. On the contrary, however, study on changes in functions or adaptations of craniofacial muscles following changes of craniofacial skeletal structures has been somewhat insufficient. The author's purpose was to observe correlations between masticatory muscular functions and change patterns according to cranial skeletal structures and occlusion patterns, for this, comparative study of muscle activity changes of preand post- orthognathic surgery states in skeletal Cl III malocclusion patients was peformed. The selected sample groups were 15 normal male patients, 15 skeletal Cl III pre-orthognatic surgery patients and 15 skeletal Cl III post-orthognatic surgery patients. For each sample groups, cephalometric x-ray taking, masticatory efficiency test and measurements of muscle activities in anterior temporal muscle, masseter and upper lip in rest, clenching, chewing and swallowing were carried out. The following results were obtained : 1. In resting state of mandible, pre-surgery malocclusion group showed higher m. activities in ant. temporalis, masseter and upper lip than post-surgery group. Post-surg. malocc. group showed significantly high m. activity only in upper lip compared to the normal group. 2. In clenching state, post-surg. malocc. group showed higher m. activities in ut. temporalis, masseter and upper lip than pre-surg. malocc. group. 3. In chewing state, post-surg. malocc. group showed higher m. activities in ant. temporalis and masseter than pre-surg. malocc. group, on the other hand, decreased upper lip activity was noticed. 4. In swallowing state, post-surg. malocc. group showed lower upper lip activity than pre-surg. malocc. group but higher than that of the normal group. No significant difference in m. activities of ant, temporalis and masseter was noticed among the three groups. 5. Masticatory efficiency was lower in pre-surg. malocc. group than normal group, masticatory efficiency showed an increase in post-surg. malocc. group compared to the pre-surg. malocc. group. However, both groups showed significant differences compared to the normal group.