• Korean Chemical Engineering Research
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• v.52 no.2
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• pp.141-153
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• 2014

Droplet based microfluidic systems have been developed for the application of biological and chemical research field. A picoliter droplet in microfluidic device provides a compartmentalized and well-defined reactor in miniaturized system. The microfluidic system with small droplets can reduce reagent cost and enhance efficiency through automated high-throughput screening system. In this review, we summarize the functionality of droplet based microfluidic system including droplet generation, precise droplet control, and various applications. In addition, this article reviews current applications in chemistry and biology, and discuss advantages of droplet based microfluidics compared with conventional manner.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2003.10a
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• pp.38-38
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• 2003

• Journal of the KSME
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• v.50 no.11
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• pp.28-30
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• 2010

이 글에서는 미세유체 기술을 활용하여 혈관 내의 유동에 의하여 발생하는 전단응력이 혈관 내부의 다양한 세포의 기능 및 상호작용에 미치는 영향을 연구하는 기술에 대하여 소개하고자 한다.

• Journal of the KSME
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• v.50 no.11
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• pp.39-42
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• 2010

이 글에서는 미세유체시스템을 이용하여 암의 전이과정을 분석하고 관련된 치료제 및 기술을 개발하는 다양한 연구 성과에 대해 소개하고자 한다.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.26 no.5
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• pp.506-513
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• 2015

In this paper, we proposed a novel ethanol concentration sensor using microfluidic metamaterial absorber. The metamaterial absorber comprises a split-ring-cross resonator(SRCR) and a microfluidic channel. The SRCR can generate LC resonance that is very sensitive to changes in the effective dielectric constant around the capacitive gap. In addition, microfluidic channels can change the effective dielectric constant of the dielectric substrate by using an infinitesimal quantity of a liquid on the order of microliters. The proposed absorber can detect the electrical properties of different concentration of ethanol. The performance of the proposed absorber is demonstrated using the absorption measurements of a fabricated prototype sample with waveguides. In addition, the simulated results and measurement results show good agreement.

• Korean Chemical Engineering Research
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• v.59 no.4
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• pp.639-643
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• 2021

In this study, fluorinated ethylene propylene (FEP) nanoparticle as an adhesive for fabricating a three-dimensional multilayered microfluidic device was studied. The formation of evenly distributed FEP nanoparticles layer with 3 ㎛ in thickness on substrates was achieved by simple spin coating of FEP dispersion solution at 1500 rpm for 30 s. It is confirmed that FEP nanoparticles transformed into a hydrophobic thin film after thermal treatment at 300 ℃ for 1 hour, and fabricated polyimide film-based microfluidic device using FEP nanoparticle was endured pressure up to 2250 psi. Finally, a three-dimensional multilayered microfluidic device composed of 16 microreactors, which are difficult to fabricate with conventional photolithography, was successfully realized by simple one-step alignment of FEP coated nine polyimide films. The developed three-dimensional multilayered microfluidic device has the potential to be a powerful tool such as high-throughput screening, mass production, parallelization, and large-scale microfluidic integration for various applications in chemistry and biology.

• Korean Chemical Engineering Research
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• v.50 no.4
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• pp.733-737
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• 2012

This study reports the microfluidic preparation of monodisperse multiple emulsions using hydrodynamic control. To generate multiple emulsions, we fabricate a microfluidic capillary device based on co-flowing stream without any surface modification of microchannels. Based on the system, we can successfully generate multiple emulsions (W/O/W) using water containing 0.5 wt% Tween 20, n-hexadecane with 5 wt% Span 80, and 10 wt% poly (vinyl alcohol) (PVA) aqueous solution, respectively. Furthermore, we control the number of inner droplets by modulation of flow rate of inner fluid at fixed flow rate of middle and outer fluid. The multiple emulsions having precisely controlled inner droplets' size and number can be applicable for multiple chemical reactions as an isolated microreactor.

• Journal of Korea Multimedia Society
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• v.12 no.3
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• pp.445-450
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• 2009

This paper presents a multi-phase fluid simulation that realistically represents small scale details. We achieve this by creating escaped particles based on physical methods. Escaped particles are the remained particles after correcting levelset. Generation of escaped particles in this paper differs from previous works; this fluid simulation is extended by adding lift force and drag force to positive escaped particles. And negative escaped particles represent droplet or splash effect; when they are merged into the negative levelset value, they affect the nodes' velocity (two-way coupling). This simulation that uses positive and negative escaped particles deals with detailed fluid motions dynamically in small scale.

• The KSFM Journal of Fluid Machinery
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• v.6 no.3 s.20
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• pp.92-96
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• 2003

• Journal of the Korean earth science society
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• v.30 no.1
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• pp.19-32
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• 2009

Paleostress was interpreted by analyzing the healed microcracks and the secondary fluid inclusions in quartz of the Jurassic granites distributed in the southwestern Ogcheon Folded Belt, South Korea. The most dominant direction of healed microcracks in the study area was oriented $N30^{\circ}W$, and $N70^{\circ}W$ direction was also recognized. The formation temperatures of fluid inclusions were ranged $380-550^{\circ}C$ and the age of healed microcrack formations might have been approximately 166-200 Ma. Comparing the paleostress orientation obtained from the direction of healed microcracks to the formation age of healed microcracks estimated from the secondary fluid inclusions, it is considered that granitic rock body in study area was subject to a maximum horizontal principal stress along the NNW-SSE and WNW-ESE directions in the early Jurassic to middle Jurassic.