• Journal of the Society of Cosmetic Scientists of Korea
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• v.49 no.1
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• pp.59-65
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• 2023

We validated the physiological activity of Syzygium claviflorum (Roxb.) Wall. ex A.M. Cowan & Cowan (S. claviflorum) extracts (leaves, stems, fruits, and flowers) as a cosmetic ingredient. Firstly, S. claviflorum extracts removed over 80% of free radicals at various concentrations in antioxidant experiments using the DPPH and ABTS assay. In cytotoxicity experiments using human epidermal keratinocytes, S. claviflorum extracts showed low cytotoxicity. In addition, S. claviflorum extracts significantly increased the expression of keratin (KRT)1, KRT2, KRT9, KRT10, which are differentiation markers of keratinocytes, as well as genes involved in the maintenance of skin barrier function, including involucrin (IVL), loricrin (LOR), filaggrin (FLG), and claudin1 (CLDN1). In particular, the expression of FLG protein, inhibited by interleukin (IL)-4/IL-13 in atopic dermatitis, was restored by S. claviflorum extracts in in vitro experiments. Therefore, S. claviflorum extracts with excellent antioxidant efficacy and skin barrier improvement function will be useful materials for the development of future atopic dermatitis treatments and cosmetics.

• Journal of Marine Life Science
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• v.8 no.1
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• pp.43-49
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• 2023

This study applied a metagenomic analysis of the penguins' gut microbiome from fecal samples of Adélie Penguin (Pygoscelis adeliae) and Emperor Penguin (Aptenodytes forsteri) living along the Ross Sea, Antarctica. As a result of taxonomic analysis, 7 phyla and 18 families were mainly present in the gut microbiome of Adélie and Emperor penguins. To assess microbial diversity, we performed alpha diversity and OTU abundance analyses. It was confirmed that the Adélie Penguin's gut microbial species had a higher diversity than Emperor Penguin's. Based on the Beta diversity analysis using PCoA, differences were observed in the clustering between Adélie and Emperor penguins, respectively. Through the KEGG pathway analysis using PICRUSt, the nucleoside and nucleotide biosynthesis pathway was the most prevalent in Adélie and Emperor penguins. This study enabled a comparison and analysis of the composition and diversity of the gut microbiome in Adélie and Emperor Penguins. It could be utilized for future research related to penguin feeding habits and could serve as a foundation for analyzing the gut microbiomes of various other Antarctic organisms.

• Industry Promotion Research
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• v.8 no.2
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• pp.119-132
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• 2023

The purpose of this paper is to re-establish the concept of Eastern time, which is used in Myeongliology and Kimun-dungap, and to discuss the use of real-time of the sun according to the birth area, the selection of real-jasi between night-jasi and real-jasi, and the exact meaning of birth time. The conventional use of time in Korean society uses Tokyo as standard time and uses a time system in which a new day begins at midnight. Howev er, what is important is not social univ ersality but the time and space of the univ erse where I was born, which is the center of the universe, should be the standard of my fate, so I have to use the longitude of the place where I was born to determine my exact time. Also it is argued that real-jasi should be selected for the selection problem of night-jasi and real-jasi, which has long been a controversial topic in Myeongliology, because the flow of cosmic energy is signaled an hour ahead. To secure the validity of setting such time, a case analysis was conducted using the time adjustment method through the spread of Kimun-dungap. Through in-depth interviews with the analysis subjects, the lives of the past were collected by date and time, and then Kimun-dungap checked whether the timing of each life event was accurate.

• Journal of Industrial Convergence
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• v.21 no.4
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• pp.65-72
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• 2023

This study's purpose is to verify how the periodically designated auditor in the recently implemented periodic auditor designation system affects audit quality. In this study, hypotheses were established by reviewing previous studies, and 980 samples of 2019 and 2020 were selected for KOSPI-listed companies. Dechow & Dichev (2002)'s accrual quality was used as the dependent variable, and the effect of whether or not a company was periodically designated as an auditor and whether or not a Big 4 auditor was selected was empirically analyzed. As a result of the analysis and correlation analysis, a statistically significant difference was confirmed in the quality of the dependent variable accrual and the independent variable designated auditor (PA). However, as a result of the regression analysis model 1, it was found that the designated auditor was not significant, but it was confirmed that there was a significant difference in the control variables. Further analysis confirmed the difference in audit quality according to the Big 4 auditors. This study is significant in that it is a study that uses empirical data to study the effect of audit quality and the selection of regularly designated auditor companies after the introduction in 2019 and 2020. Due to the non-disclosure of government-designated companies, there is a limit that there may be a difference from the selection based on the researcher's published selection criteria.

• The Korean Journal of Mycology
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• v.50 no.1
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• pp.65-73
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• 2022

This study aimed to isolate wild yeasts from seawaters and soils samples of the Haeundae and Mongdol beaches on the southern coast of Korea, and to characterize these unrecorded wild yeast strains. In total, 41 strains, representing 37 different species of wild yeast were isolated from 70 samples collected from the beaches. Among these, 14 strains were isolated from the alkalophilic medium of yeast extract-peptone-dextrose (YPD) medium (pH 9.0), and 27 strains were isolated concurrently on general YPD medium (pH 6.5). Among the 41 isolated wild yeast strains, Candida insectorum HUD 16-3(JSL-KSS-002) and Metschnikowia citriensis HUD 12-5(JSL-KSS-001) had not previously been recorded. We investigated the microbiological characteristics of these two unrecorded yeast strains and three other strains-, Cystobasidium lysinophilum JSC 52-2(JSL-GGU-019), Candida takata NMD 11-1(JSL-GGU-017) and Candida panamensis ASG 58M-2(JSL-GGU-018) from Jangseoncheon in Jellabuk-do and Jangtaesan in Deajeon city. All five previously unrecorded yeasts were oval and did not form spores. All strains grew well in YPD and yeast extract-malt extract media in a vitamin-free medium. Two strains, including C. insectorum HUD 16-3(JSL-KSS-002) grew well in a 15% NaCl-containing YPD medium. Three strains, including Cys. lysinophilum JSC52-2(JSL-GGU-019) assimilated lactose, and all strains assimilated starch.

• The Korean Journal of Mycology
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• v.51 no.1
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• pp.39-49
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• 2023

This study aimed to screen and investigate the microbiological characteristics, enzyme activity, and physiological functionality of unrecorded wild yeasts from the Wolsung valley of South Deogyu mountain and Jinjamcheon in Daejeon city, Korea. Candida sorboxylosa WSC25-4 (NNIBRFG47336), Arxula adeninivorans WSC6-3 (NNIBRFG47335), Farysizyma taiwaniana JRC6-2 (NNIBRFG47339), Saturnispora dispora JTS19-1 (NNIBRFG47334), Vanderwaltozyma polyspora JJCH5-3 (NNIBRFG47337), and Vanrija fragicola SW-9 (NNIBRFG47338) have not been previously recorded. None of these formed spores or pseudo-mycelium, and four strains, including C. sorboxylosa WSC25-4, were global in shaped. Except for V. polyspora JJCH5-3, all strains grew well in the yeast extract-peptone-dextrose (YPD), potato-dextrose and yeast malt extract media. A. adeninivorans WSC6-3 and S. dispora JTS19-1 grew well in 40% glucose-containing YPD medium and V. fragicola SW-9 in 5% NaCl-containing YPD medium. The supernatant of A. adeninivorans WSC6-3, F. taiwaniana JRC6-2, and V. fragicola SW-9 exhibited 58.0, 59.0, and 59.0% of glucoamylase activity, respectively. C. sorboxylosa WSC25-4 also produced extracellular alkaline protease. Antioxidant activity of the supernatant from F. taiwanian JRC6-2 was high (79.8%), while the other five unrecorded yeasts demonstrated elevated antiaging superoxide dismutase (SOD)-like activity (99%). Anti-gout xanthin oxidase inhibitory activity of S. dispora JTS19-1 and V. fragicola SW-9 was also elevated at 79 and 80%, respectively.

• The Korean Journal of Mycology
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• v.50 no.3
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• pp.149-160
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• 2022

The goal of this study was to investigate the diversity of wild yeasts from the waters and soils of Haegeumgang in Gyungsangnam-do, and Namdaecheon and Geumsancheon in upstream of Geumgang, Korea and to characterize any previously unrecorded wild yeast strains. In total, 52 strains comprising 22 different species of wild yeasts were isolated from 35 samples obtained from Haegeumgang. Forty three and sevent nine wild yeast strains were isolated from 90 samples taken from Namdaecheon and Geumsancheon, respectively. Among the total 174 isolated wild yeast strains, 4 strains, i.e., Exobasidium rhododendri HGG10-5 (NNIBR2022633FG1), Udeniomyces pyricola NDC29-1 (NNIBR2022633FG2), Diddensiella caesifluorescens GSC2-2 (NNIBR2022633FG5) and Pichia scaptomyzae BAC2-3 (NNIBR2022633FG4) were previously unrecorded yeasts were oval or spherical in shape, only Pichia scaptomyzae BAC 2-3 formed ascospores. Three strains with the exception of Udeniomyces pyricola NDC 29-1 grew well in vitamin-free medium and Exobasidium rhododendri HGG 10-5 grew well in YPD medium containing 10% NaCl. All four novel strains assimilated fructose, lactose, raffinose, starch and xylose.

• Korean Journal of Environmental Biology
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• v.39 no.4
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• pp.486-494
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• 2021

Watermelon (Citrullus lanatus (Thunb.) Matsum. & Nakai) is sensitive to low temperature and shows retarded growth under 10℃. Although early transplanting guarantees higher returns, it requires cost and labor to maintain the appropriate temperature for plant growth. Therefore, cultivars tolerant to chilling stress is necessary to reduce the cost and labor requirements. The purpose of this study is to analyze data on plant growth and fruit enlargement under continuous chilling night temperature to develop new cultivars tolerant to chilling temperature. Two cultivars expected to have chilling tolerance and another cultivar sensitive to chilling temperature were grown in greenhouses with chilling and optimal night temperature conditions. In the early growth stage after transplanting, the cultivars expected to have chilling tolerance showed better vine length, fresh weight and dry weight. However, one of the tolerant cultivars showed significantly lower vine length, leaf length and width, and petiole length than the sensitive cultivar during pollination period and later growth stage, showing genotype specific responses. The fruit length, width, and weight were also significantly lower in the tolerant cultivar. The fruit set ratio was significantly higher in the chilling sensitive cultivar than the two tolerant cultivars. These results suggest that the present chilling tolerant cultivars in watermelon were selected based on their performance in the early growth stage, and further studies on chilling tolerance in different growth and development stages are required to develop cultivars adapted to various forcing cultivation systems.

• Journal of Korea Society of Industrial Information Systems
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• v.28 no.2
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• pp.1-9
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• 2023

Research using AI and big data is also being actively conducted in the health and medical fields such as disease diagnosis and treatment. Most of the existing research data used cohort data from research institutes or some patient data. In this paper, the difference in the prediction rate of survival and the factors affecting survival between breast cancer patients in their 40~50s and other age groups was revealed using health insurance review claim data held by the HIRA. As a result, the accuracy of predicting patients' survival was 0.93 on average in their 40~50s, higher than 0.86 in their 60~80s. In terms of that factor, the number of treatments was high for those in their 40~50s, and age was high for those in their 60~80s. Performance comparison with previous studies, the average precision was 0.90, which was higher than 0.81 of the existing paper. As a result of performance comparison by applied algorithm, the overall average precision of Decision Tree, Random Forest, and Gradient Boosting was 0.90, and the recall was 1.0, and the precision of multi-layer perceptrons was 0.89, and the recall was 1.0. I hope that more research will be conducted using machine learning automation(Auto ML) tools for non-professionals to enhance the use of the value for health insurance review claim data held by the HIRA.

• Journal of the Korea Society of Computer and Information
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• v.14 no.3
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• pp.93-101
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• 2009

This paper suggests a new algorithm automatically searching for Region-of-Interest(ROI) with high speed, using the edge information of high frequency subband transformed with wavelet. The proposed method executes a searching algorithm of 4-direction object boundary by the unit of block using the edge information, and detects ROIs. The whole image is splitted by $64{\times}64$ or $32{\times}32$ sized blocks and the blocks can be ROI block or background block according to taking the edges or not. The 4-directions searche the image from the outside to the center and the algorithm uses a feature that the low-DOF image has some edges as one goes to center. After searching all the edges, the method regards the inner blocks of the edges as ROI, and makes the ROI masks and sends them to server. This is one of the dynamic ROI method. The existing methods have had some problems of complicated filtering and region merge, but this method improved considerably the problems. Also, it was possible to apply to an application requiring real-time processing caused by the process of the unit of block.