• YAKHAK HOEJI
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• v.52 no.6
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• pp.452-465
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• 2008

Hair analysis for drugs of abuse offers the crucial potential advantage when compared to urine, such as the longer time window of drug intake, which makes retrospective investigation of chronic and/or past consumption. This paper reviews the physiological basis of hair growth, mechanism of drug incorporation, analytical methods, result interpretation and practical application of hair analysis. Moreover, to facilitate the court's decision regarding specific circumstances surrounding the crime, this review demonstrated that the results of hair analysis not only should be admitted as scientific evidence of drug use but also could legally improve reliability of the evidence.

• Journal of the Korean Applied Science and Technology
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• v.37 no.5
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• pp.1298-1305
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• 2020

Objective: The study aimed to understand the degree of improvement in damaged hair by applying mink oil. Methods: The agent used to improve hair texture is mink oil, which was applied in varying dosages (0, 1, 2, and 3 g). Hair characteristics were measured before and after applying mink oil to bleached hair for comparative analysis. To understand the effects of mink oil on hair texture, tensile strength, absorbance, and gloss were measured. Results: The results indicate a decrease in the tensile strength of damaged hair compared with healthy hair. Tensile strength at level 7 was achieved with high dosages of mink oil. Furthermore, the experimental group demonstrated an increase in absorbance compared with control. Compared to 0g for the control group, the absorbance values for the experimental group with mink oil dosages of 1, 2, and 3 g at level 7 decreased with the increased in mink oil dose. In terms of gloss, an increase was observed for bleached hair compared with healthy hair. At level 7, gloss decreased with the increase in mink oil dose. Conclusions: The results verified the improvement in hair texture after the application of mink oil to damaged hair. Future research should explore the effects of various oil ingredients on hair texture.

• Proceedings of the Korean Society for Food Science of Animal Resources Conference
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• 2005.10a
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• pp.317-318
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• 2005

• Journal of KIISE:Software and Applications
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• v.31 no.2
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• pp.137-152
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• 2004

Assesment of 30 nutritional minerals and 8 toxic elements in hair are very important not only for determining adequacy, deficiencies and unbalance, but also for assessing their relative relationships in the body. A test has been developed that serves this purpose exceedingly well. This test is known as tissue mineral analysis(TMA). TMA is very popular method in hair mineral analysis for health care professionals in over 46 countries' medical center. However, there are some problems. First, they do not have database which is suitable for korean to do analyze. Second, as the TMA results from TEI-USA is composed of english documents and graphic files prohibited to open, its usability is very low. Third, some of them has low level database which is related to TMA, so hairs are sent to TEI-USA for analyzing and medical services. it bring about an severe outflow of dollars. Finally, TMA results are based on the database of american health and mineral standards, it is possibly mislead korean mineral standards. The purposes of this research is to develope the first Intelligent Medical Expert System(IMES) of TMA, in Korea, which makes clear the problems mentioned earlier IMES can analyze the tissue mineral data with multiple stage decision tree classifier. It is also constructed with multiple fuzzy rule base and hence analyze the complex data from Korean database by fuzzy inference methods. Pilot test of this systems are increased of business efficiency and business satisfaction 86% and 92% respectively.

• Korean Journal of Food Science and Technology
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• v.54 no.1
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• pp.43-51
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• 2022

Regulation of the hair follicle cycle in association with dermal papilla cells is one of the most interesting targets for promoting hair regrowth. In this study, we examined whether steam-dried Betula platyphylla extracts (BPE) promote hair growth by upregulating in vitro and in vivo responses of dermal papilla cells. The data showed that BPE3 contained high amounts of phenolic compounds with higher antioxidant effects and increased hair growth-related genes, including fibroblast growth factor7 and Wnt7b, in dermal papilla cells. Notably, BPE3 effectively enhanced the formation of hair follicles by increasing FGF7, Wnt7b, and vascular endothelial growth factor in C57BL/6N dorsal skins. Additionally, BPE3 significantly decreased the expression of inflammatory repertoires, inducible nitric oxide synthase, interleukin-6, and cyclooxygenase 2. Several small molecules, such as betulin and unsaturated fatty acids, support the pharmacological activity of BPE3. In conclusion, BPE3 effectively promoted hair growth by activating dermal papilla cells and enhancing hair follicle cycles by attenuating the inflammatory environment in the scalp.

• Journal of the Korea Convergence Society
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• v.10 no.6
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• pp.281-286
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• 2019

Appearance is a means of competitiveness for modern people, and one of the factors that harms the desires of modern people is white hair. For the modern man who needs to express beautiful appearance to others by covering white moth, we performed hair analysis after white moth hair dye treatment. The maximum modulus and tangential modulus according to the maximum load, maximum tensile strength, maximum elongation, breaking load, fracture strength, elongation at break, and evaluation interval between 1N-3N experimental group and control group of 1N-Respectively. Maximum load, maximum tensile strength, breaking load and breaking strength tended to be larger than those of the control group, while the maximum elongation and breaking elongation were the highest in the control group and the elongation decreased with the experimental group treatment. The maximum modulus and tangential modulus of the 1N-3N test group were higher than those of the control group at 0~0.15 and 0.15~2.5, respectively. Based on the study on the cosmetic changes of the hair before and after the treatment, it can be used as a basic data to select the correct oxidative hair dye product, the proper amount of application and the time to leave.

• Journal of Life Science
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• v.33 no.3
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• pp.234-241
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• 2023

At present, many countries around the world are legalizing cannabis and its products, and research on various treatments using cannabis is being actively conducted. However, the cannabis plant contains other compounds whose biological effects have not yet been established. We investigated the effect of cannabidiol (CBD) on hair growth in human dermal papilla cells (HDPCs). 2,2'-Azino-bis (3-ethylbenzothiazolin-6-sulfonic acid) (ABTS) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assays were performed to determine the antioxidant activity of CBD. The HDPCs viability of CBD was examined via water-soluble tetrazolium salt (WST-1) assay. The expression of hair-loss-related markers in HDPCs by CBD treatment was analyzed by real-time PCR and western blotting. The DPPH, ABTS radical scavenging activity assay showed that CBD had superior antioxidant activities. In HDPCs, CBD increased cellular proliferation at concentrations without cytotoxicity. It also increased the expressions of fibroblast growth factor 1 (FGF1), fibroblast growth factor 7 (FGF7), vascular endothelial growth factor (VEGF), and insulin-like growth factor (IGF). These results correlated with a decrease in the expression of inhibition-related factors, such as androgen receptor (AR) and transforming growth factor beta 1 (TGF-B1). Moreover, CBD resulted in a significant increase in the phosphorylation of AKT and extracellular signal-regulated kinase (ERK). Therefore, it is suggested that CBD may be a potential remedy for the treatment of alopecia.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.14 no.4
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• pp.157-163
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• 2014

User's sensitivity is recognized as a very important parameter for communication between company, government and personnel. Especially in many studies, researchers use voice tone, voice speed, facial expression, moving direction and speed of body, and gestures to recognize the sensitivity. Multiplex modality is more precise than single modality however it has limited recognition rate and overload of data processing according to multi-sensing also an excellent algorithm is needed to deduce the sensing value. That is as each modality has different concept and property, errors might be happened to convert the human sensibility to standard values. To deal with this matter, the sensibility expression modality is needed to be extracted using technologies like analyzing of relational network, understanding of context and digital filter from multiplex modality. In specific situation to recognize the sensibility if the priority modality and other surrounding modalities are processed to implicit values, a robust system can be composed in comparison to the consuming of computer resource. As a result of this paper, it is proposed how to assign the weight of multiplex modality using implicit data.

• Korean Journal of Food Science and Technology
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• v.43 no.3
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• pp.381-386
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• 2011

This study investigated the effect of herbal extracts fermented by Lactobacillus plantarum (MBN) on hair growth in C57BL/6 mice and HaCaT cells. Five week old mice were applied with MBN topically (0.2 mL) once per for 21 days. Hair regrowth was evaluated by gross examination and verified by hematoxylin-eosin staining. Gene expression of vascular endothelial growth factor (VEGF), keratinocyte growth factor (KGF), and transforming growth factor-beta1 ($TGF{\beta}1$), relevant to hair growth, were examined. The data revealed that MBN successfully promoted hair growth in both male and female mice at a dose between 200-500 mg/kg and improved hair thickness. The VEGF and KGF genes were expressed in a dose-dependant manner, whereas $TGF{\beta}1$ was not expressed. Moreover, nitric oxide was significantly increased, suggesting an improvement in blood flow. These results indicate that MBN effectively promoted hair growth and gene expression relevant to hair growth in an animal model.

• Journal of the Korean Society of Food Science and Nutrition
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• v.46 no.6
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• pp.671-680
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• 2017

This study was conducted to examine the effects and potential mechanisms of action of black soybean extracts and fermented black soybean extracts by Lactobacillus rhamnosus GG (LGG) and Bifidobacterium animals subsp. lactis BB-12 (BB-12) on proliferation of human follicle dermal papilla cells (HFDPC). We examined changes in pH, total polyphenol, sugar, and reducing sugar contents according to fermentation period of black soybean extracts. Assay using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide was performed to determine cell toxicity levels of the four black soybean extracts [black soybean water extract (BWE), black soybean ethanol extract (BEE), fermented BWE (F-BEW), and fermented BEE (F-BEE)]. Changes in mRNA expression levels of hair growth promoting factors and hair growth inhibiting factors by the four black soybean extracts were measured by real-time PCR. In addition, phosphorylation levels of mitogen-activated protein kinase family proteins were measured by western blot analysis. As a result, fermentation of black soybeans significantly reduced pH, total polyphenols, and sugar/reducing sugar contents. All four black soybean extracts showed no cellular toxicity in HFDPC. In fact, BEE significantly enhanced cell viability of HFDPC at $100{\mu}g/mL$ compared to control. BWE, BEE, and BWE-F significantly increased mRNA expression of vascular endothelial growth factor, and all four extracts increased mRNA expression of fibroblast growth factor. However, mRNA expression levels of apoptosis-related genes were not affected by black soybean extracts in HFDPC. Furthermore, BWE, BEE, and BWE-F significantly increased phosphorylation levels of extracellular signal-regulated kinase compared to control. Taken together, we demonstrated that black soybean extracts enhanced proliferation of human follicle dermal papilla cells partially via activation of hair growth promoting factors, although no particular significant effects on proliferation were observed by fermentation of black soybeans.