• Korean Journal of Food Science and Technology
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• v.35 no.4
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• pp.708-712
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• 2003

This study was carried out to examine the effects of fermentation conditions on the production of erythritol by osmophilic yeast Candida magnoliae. It was found that sucrose was superior to glucose as carbon source and 109 g/L erythritol was produced from 400 g/L sucrose. When yeast extract was used as nitrogen source, maximum values of yield and productivity for erythritol were obtained at 15 and 20 g/L of yeast extract, respectively. A mixture of 15 g/L yeast extract and 3 g/L ammonium phosphate allowed more efficient utilization of sucrose and hence resulted in 149 g/L of erythritol, 0.37 g erythritol/g sucrose of erythritol yield and $0.78\;g/L{\cdot}hr$ of erythritol productivity. A batch fermentation supplemented with 40 g/L KCl resulted in an erythritol concentration of 167 g/L and an erythritol yield of 0.42 g erythritol/g sucrose.

• The Transactions of the Korean Institute of Electrical Engineers D
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• v.55 no.11
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• pp.502-510
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• 2006

In this paper, we describe implementation of a computer access device for the severly motor-disability. Many people with severe motor disabilities need an augmentative communication technology. Those who are totally paralyzed, or 'locked-in' cannot use conventional augmentative technologies, all of which require some measure of muscle control. The forehead is often the last site to suffer degradation in cases of severe disability and degenerative disease. For example, In ALS(Amyotrophic Lateral Sclerosis) and MD(Muscular dystrophy) the ocular motorneurons and ocular muscles are usually spared permitting at least gross eye movements, but not precise eye pointing. We use brain and body forehead bio-potentials in a novel way to generate multiple signals for computer control inputs. A bio-amplifier within this device separates the forehead signal into three frequency channels. The lowest channel is responsive to bio-potentials resulting from an eye motion, and second channel is the band pass derived between 0.5 and 45Hz, falling within the accepted Electroencephalographic(EEG) range. A digital processing station subdivides this region into eleven components frequency bands using FFT algorithm. The third channel is defined as an Electromyographic(EMG) signal. It responds to contractions of facial muscles and is well suited to discrete on/off switch closures, keyboard commands. These signals are transmitted to a PC that analyzes in a time series and a frequency region and discriminates user's intentions. That software graphically displays user's bio-potential signals in the real time, therefore user can see their own bio-potentials and control their physiological signals little by little after some training sessions. As a result, we confirmed the performance and availability of the developed system with experimental user's bio-potentials.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.1
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• pp.8-18
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• 2011

To have effective treatment for shoulder arm pain, we searched the cause, symptom, etiology, classification of the pain areas, acupuncture points, and muscles along the meridians, and acquired the following results. Shoulder-pain is mainly divided into the malfunction of viscera and entrails, damage due to the weakness of essence and qi, abnormal status of muscle function, change of joints, disease in the nerve and vessel, and the internal injury due to seven modes of emotions. Pain of shoulder joints are pain in the local area of shoulder joints, referred pain of shoulder, neck, and shoulder-arm, numbnes and swelling of muscle, and muslce weakness. Shoulder-arm pain is classified as four types of pain: shoulder-joint pain, shoulder-back pain, shoulder-chest pain, and shoulder-arm-elbow pain. And shoulder-arm-elbow pain is again divided into the shoulder-blade pain, shoulder-arm pain, shoulder-elbow pain. The related meridians on shoulder pain are the three yin meridians of hand, Kidney Meridian, Conception Meridian, three yang meridians of hand, Bladder Meridian, Governor Meridian Acupuncture points for shoulder pain are in the acupuncture points of the 10 meridians and a-shi points. Thre related meridian muscles on shoulder-pain are the three yin and yang meridians of hand, and their related muscles are the ones that are connected with the front, back, and chest side muscles of shoulder joints, and the ones that are connected with the front and back side muscles of arm.

• Microbiology and Biotechnology Letters
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• v.42 no.2
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• pp.202-206
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• 2014

A response surface method based on a central composite design experiment was used to determine the optimum conditions for pretreatment of persimmon peel. It was mathematically predicted that the maximum amount of reducing sugars would be obtained at an $H_2SO_4$ concentration of 1.77% (w/v) and a heat treatment time of 26.4 min. A reducing sugar concentration of 63.23 g/l was obtained under the optimum pretreatment conditions determined by RSM. Under anaerobic growth conditions, Saccharomyces cerevisiae NK28 produced 15.52 g/l of ethanol with a yield of 0.34 g ethanol/g glucose from pretreated persimmon peel, which corresponded to 14% and 26% enhancements in ethanol productivity and ethanol yield, respectively, compared with those obtained in aerobic growth conditions. This study suggests that persimmon peel might be a useful substrate for bioethanol production by yeast fermentation.

• Microbiology and Biotechnology Letters
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• v.42 no.2
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• pp.184-189
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• 2014

Yeast strains demonstrating fibrinolytic activity were isolated from traditional fermented soybean in Gangwon province, Korea. The AFY-1 strain isolated from fermented soybean paste showed the highest fibrinolytic activity (3.5 U/mg protein) corresponding to a 1.75 fold higher fibrinolytic activity compared with the plasmin (2.0 U/mg protein). The optimum temperature for the growth of AFY-1 strain was $32^{\circ}C$. Analysis of 18S rRNA gene sequence and carbon source utilization pattern indicated that the AFY-1 strain shares the highest homology (99%) with Saccharomycetales sp.

• Microbiology and Biotechnology Letters
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• v.48 no.2
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• pp.179-184
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• 2020

The MBY/L6793 strain showing the highest ethanol yield of 0.48 ± 0.00 g ethanol/ g glucose was isolated from Senecio cruentus. Its ethanol yield was approximately 1.5 times that of the MBY/L6986 isolated from Callistephus chinensis. The strain was identified as Hanseniaspora opuntiae by sequence analysis of the 18S rRNA gene, and the sequenced gene was registered to the GenBank (MN859968). When grown at 40℃, the strain produced 3.82 ± 0.98 g ethanol from 20 g glucose and 10.05 ± 0.06 g ethanol from 60 g glucose, corresponding to approximately 2.45 and 5.74 times, respectively, compared to the control strain H. opuntiae KCCM50747. The MBY/L6793 strain was deposited to KCTC (Korean Collection for Type Culture) as KCTC37025.

• The Journal of Korean Obstetrics and Gynecology
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• v.24 no.1
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• pp.109-131
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• 2011

Objectives: This study aims to search the clinical cases that treated leiomyoma through the traditional Chinese medicine, to understand the study trend on leiomyoma in China, and to clairfy the cause of leiomyoma and its treatment by the oriental medicine herbs. Methods: We searched the key word "leiomyoma" in the China National Knowledge Infrastructure (CNKI)[http://www.cnki.net], and narrowed its searching area to the papers published in the year 2010. Of 720 study papers, we chose 21 clinical papers on the leiomyoma, and studied the patient case, treating method, result of treatment, and checked the category, cause, treatment method of leiomyoma. Results: The results are shown in the Table 1-3. Conclusions: Leiomyoma is categorized in the traditional Chinese medicine as both lump occuring inside the body and stony abdominal lump. The main cause of leiomyoma is qi-stagnation and blood stasis, essence deficiency and pathogen affluence. The treatment method is used by activating blood and resolving stasis but harmonizing the spleen and stomach to prevent damaging healthy qi. The development herbal medicine of treating leiomyoma is Gyehongbyeolgaphwan, Gyejibongnyeonggyonang, Gungryusogyonang, Angonpyoen etc. In treating leiomyoma, the herbs were much used to regulate qi as Baekbokryung, Danggwi, Baekchul, Doin, Moryeo, Achul, Mokdanpi etc. Traditional Chinese Medicine(TCM) treatment of leiomyoma has efficiency of improve symptom but low ratio of complete recovery.

• Journal of Oriental Physiology
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• v.14 no.2 s.20
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• pp.23-41
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• 1999

The disease of cholelith is common world widely. As life expectancy gets extended and life environment and dietary life change, increased to gallstone in Korea. On the case that elimination surgery is inapplicable and for the aged patients. recently the dissolution therapy of cholelith is studied world widely. From the view of oriental medicine, the causes of gallstone, treatment methods and the effects of therapy are as follows ; 1. The attack of gallstone is by the stagnation and disturbance of qi in the body. 2. The causes of gallstone are classified into three types. 1).The type of stagnation of qi. 2).The type of damp-heat. 3).The type of noxious heat. 3. The treatment effect is high in the damp-heat type. 4. Medical treatment of gallstone, considering the function of the intestines, are lithodialysis and removol of gallstone, soothing the liver and regulating the cerculation of qi, clearing away heat and elininating dampness. 5. The dissolution therapy of gallstone effected to the size within the diameter of 1.5cm 6. Through the oriental medicine therapy, besides excretion and dissolution of gallstone, the interval extention and elimination of spasm, the prevention of relapse and aftere effect are to be expected. The study which can improve the treatment rate of cholelith through the combination therapy of oriental and western is needed and deep study on oriental medicine diagnostic and classification according to the observation based on symptoms is necessary.

• Journal of Physiology & Pathology in Korean Medicine
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• v.29 no.3
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• pp.203-217
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• 2015

Scolpendra subspinipes (centipede) is pungent in flavor, activates the channels to stop pain, and, removes toxins and resolves masses. So it has been used as a folk remedy. We researched folk remedies which used centipede as a single medicine and results of its prior clinical and experimental study, and figured out that centipedes are effective on ulcerative disease, herpes zoster, clavus, insect bite, inflammatory disease, furunculus, pain disease by external therapy, and oral administration is effective on anti-cancer such as hepatoma and uterine cancer, cerebrovascular disease, inhibition of atherosclerosis, sedation of central nervous system, antipyretic action, and anti-inflammation, and centipede Herb-Acupuncture is effective on inflammatory disease and pain disease. Centipede preparation materials for external therapy were sesame oil, perilla oil, vinegar, salt, and, burnt alum. Fumigation of centipede treated paronychia, pertussis, and hemorrhoids. For the external therapy, the way of centipede powder mixing with other materials has been used. It is needed that we use dusted powder to make skin absorb its ingredients more easily, and we study intensely minor ingredients to make centipede components absorbed more effectively and do pharmacological action. Also, fumigation, a kind of another external therapy, is considered to be effective treatment of upper respiratory infection like pertussis, so it needs an in-depth study on centipede fumigation.

• Journal of Physiology & Pathology in Korean Medicine
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• v.21 no.3
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• pp.748-754
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• 2007

Electroacupuncture is the combined treatment of mechanical and electric stimuli on the needle head, on which electricity runs after acupuncturing at the acupuncture points. It is reported that its treatment effect depends on the parameter of stimulus, which is wave of stimulus, frequency, voltage, and duration of electric current. To get the effective treatment, stimulus intensity over threshold is needed. We planned to experiment whether acupuncture effect is affected by sex, age, and weight. After we conducted electric stimulus at Zusanli(ST 36) which is known to increase small intestinal motility in normal rats, we observed the effects and got the following results. Though the increased effects of small intestinal motility of electro-acupuncture at Zusanli(ST 36) did not show the difference of sex, this effect was observed to have a tendency to decrease according to weight increase without distinction of sex. But the effect of electro-acupuncture shown in 4, 5, 7 weeks old without distinction of sex was observed to have a tendency to decrease with the growing of weeks-old in the male rat group. And the significant change without specific tendency was observed in the 4, 5 weeks old female rat group. This result suggested that sex, weight, and age should be considered to get the efficient electro-acupuncture. The more experimental study should be advanced to investigate the correlation between the factors that can affect the acupuncture treatment, and, afterward, the interconnection into the clinical use.