• Title/Summary/Keyword: 맥문동

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Pharmacognostical Studies on the Chinese Crude Drug ‘Maig Moon Dong’ (한약 "맥문동" 의 생약학적 연구)

  • Geon, Dai-Gun;Park, Jong-Hee
    • Korean Journal of Pharmacognosy
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    • v.34 no.1 s.132
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    • pp.6-9
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    • 2003
  • ‘Maig Moon Dong(麥問冬)’ is one of the chinese crude drugs used mainly to cure a cough and sputum, etc. With regard to the botanical origin of ‘Maig Moon Dong’, it has been considered to be Liriope species of Liliaceae, but there has not been studied pharmacognostically. To clarify the botanical origin of Maig Moon Dong, we studied on the anatomical characteristics of Liriope and Ophiopogon species growing wild in Korea i.e. L. platyphylla, L. spicata, O. jaburan, O. japonicus and Maig Moon Dong from Korea. As a result, the botanical origin of Maig Moon Dong from Korea was proved as Liriope platyphylla and L. spicata.

Effects of Liriopis Tuber Extracts on Lipid Metabolism in Rats Fed High Cholesterol Diet (맥문동 엑스가 고콜레스테롤 식이를 급여한 횐쥐의 지질대사에 미치는 영향)

  • Kim, Eun-Jeong;Jeong, Seong-Woon;Yang, Jun-Ho;Lee, In-Sun;Rhee, In-Ja
    • Korean Journal of Pharmacognosy
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    • v.34 no.1 s.132
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    • pp.65-69
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    • 2003
  • This study was performed to examine the effects of Liriopis Tuber extracts to high cholesterol diet on lipid metabolism in rats. Male Sprague-Dawley rats of $90{\pm}10\;g$ were divided into six groups; basal diet (normal group), 1% high cholesterol diet (control group), high cholesterol diet supplemented with 3%, 5% water extracts (C3W, C5W group) and high cholesterol diet supplemented with 3%, 5% MeOH extracts (C3M, C5M group). These experimental diets were fed for 4 weeks. The lipid contents on serum, liver, feces were lower Lriopis Tuber extracts groups than control group. Especially, the effects of water extract was better than MeOH extract.

Effects of shading on the growth of variegated liriope (Liriope platyphylla Wang et Tang. forma variegata Hort) (차광이 반입맥문동(Liriope platyphylla Wang et Tang. forma variegata Hort.)의 생육에 미치는 영향)

  • 최상태;김지은;박인환;안형근;김성태
    • Asian Journal of Turfgrass Science
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    • v.15 no.2
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    • pp.77-86
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    • 2001
  • The experiments were carried out to investigate effect of shading rare on variegata appearance and leaf growth of variegated liriope (Liriope platyphylla Wang et Tang variegata Hort.) The plant was grown under four different light intensities such as 0(natural light intensity), 25, 50 and 75% shading conditions. Leaf variegata appearance was better in the light than in the shade. Leaf showed good growth at 0, 25% shading treatment, average leaf width and area of yellow part were highest at 0% shading treatment. As increased shading rate, number of stomate per unit area decreased. Total chlorophyll of the whole leaf and green part were reduced by increasing shading rate, while yellow part showed oppositely. In the epidermis, cell size of 75% shading treatment showed larger than those of 0% shading treatment.

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한방생약제품의 제제 유형에 따른 중금속 함량 연구(II)

  • O, Seong-Yun;An, Guk-Won;Bu, Lee Ti Tu Ha;Park, Mun-Gi
    • Proceedings of the Korean Environmental Sciences Society Conference
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    • 2007.05a
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    • pp.577-579
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    • 2007
  • 탕액으로 제조된 생약제제 4개 제품의 중금속의 농도는 허용치보다 낮게 검출이 되었으며, 맥문동탕의 경우 As의 농도는 0.048ppm, Cd의 농도는 0.0001ppm, Pb의 농도는 0.002ppm, Hg의 농도는 0.003ppm으로 측정되었으며, 갈근탕의 경우 As의 농도는 0.05ppm, Cd의 농도는 0.0002ppm, Pb의 농도는 0.003ppm, Hg의 농도는 0.003ppm으로 측정되었고, 쌍화탕의 경우 As의 농도는 0.063ppm, Cd의 농도는 0.001ppm, Pb의 농도는 0.004ppm, Hg의 농도는 0.002ppm으로 측정되었으며 20전 대보탕의 경우 As의 농도는 0.049ppm, Cd의 농도는 0.001ppm, Pb의 농도는 0.0185ppm, Hg의 농도는 0.003ppm으로 측정되었다.

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General Components and Sensory Evaluation of Hot Water Extract from Liriopis Tuber (맥문동 열수 추출물의 일반성분과 관능평가)

  • 김순동;구연수;이인자;김일두;윤광섭
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.30 no.1
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    • pp.20-24
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    • 2001
  • This study was conducted to analyze the general components and to investigate sensory evaluation of hot water extract prepared by boiling at 10$0^{\circ}C$ for 3 hr with 4-fold water. The contents of total soluble soild, non-reducing sugar, total saponin, ash and total protein were 15.95%, 6.54%, 1.735, 0.33% and 0.40%, respectively. The contents of succinic, malic and acetic acid in the extracts were 111.48 mg%, 23.67mg% and 18.36mg%, respectively. The major free amino acids and minerlas of the extract were hydroxyproline 1,290.0 $\mu\textrm{g}$%, glutamic acid 456.2$\mu\textrm{g}$% and potassium 151.35 mg%, respectively. Bitter taste in the extract was not observed, whereas sweet, sour and astringent taste were observed.

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The Effects of Sasammaickmoondong-tang against Colonic Mucosal Lesions (사삼맥문동탕이 Indomethacin으로 유발된 mouse의 대장 점막 손상에 미치는 영향)

  • 최준혁;임성우
    • The Journal of Korean Medicine
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    • v.23 no.4
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    • pp.169-185
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    • 2002
  • Objectives: This study was carried out to investigate 1he effects of Sasammaickmoondong-tang(SME) on colonic mucosal lesions induced by indomethacin in mouse. Methods: The normal group is 1hat no inflammation elicitated mouse. Control group is that gastro-inflammation elicitated mouse. Sample group is that SME administered mouse after gastro-inflammation elicitation. Results: In the common morphology and histochemical change, control group was observed various injury-mucous surface cell, micro-villi, paneth cell, surface epithelial cell, goblet cell-by hemorrhagic erosion, while sample group was as same as normal group. In the immunohistochemical change, 1he distributions of COX-1, Bcl-2, and BrdU treated with SME noticeably increased than control group(P<0.05). The distributions of TUNEL, $NF-{\kappa}B$, COX-2, $IL-2R-\alpha$, NK-1.1, ICAM-1, and CD11b/18 treated with SME noticeably decreased than control group(P<0.05). And the distribution of SBA was as same as normal group. Conclusions: According to the above results, it is supposed that Sasammaickmoondong-tang is applicable to colonic mucosal lesions.

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The Effects of Sasammaickmoondong-tang against Gastric Mucosal Lesions (Mouse의 위점막 염증에 대한 사삼맥문동탕의 면역반응 연구)

  • 김주성;임성우
    • The Journal of Korean Medicine
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    • v.24 no.2
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    • pp.121-137
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    • 2003
  • Objectives: This study was carried out to investigate the effects of Sasammaickmoondong-tang (SME) on gastric mucosal lesions induced by indomethacin in mice. Methods: The normal group was no inflammation-induced mice. The control group was gastro-inflammation-induced mice. The sample group was mice administered SME after gastro-inflammation elicitation. Results: In the common morphology and histochemical change, the control group was observed with various injury-mucous surface cell, micro-villi, paneth cell, surface epithelial cell, goblet cell - by hemorrhagic erosion, while the sample group was as same as the normal group. In the immunohistochemical change, the distributions of COX-1, Bcl-2, and BrdU treated with SME were noticeably higher than in the control group (p<0.05). The distributions of TUNEL, NF-B, COX-2, IL-2R-, NK-1.1, ICAM-1, and CD11b/18 in those treated with SME were noticeably lower than in the control group (p<0.05). Finally, the distribution of SBA was the same as in the normal group. Conclusions: According to the above results, it is supposed that Sasammaickmoondong-tang is applicable to gastric mucosal lesions.

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A Study on Maekmundong(Liriope platyphyllla) of Soyosan in "Dong-uibogam(東醫寶鑑)" ("동의보감(東醫寶鑑)"의 소요산(逍遙散)에 포함된 맥문동(麥門冬)에 관한 고찰(考察))

  • Song, Ji-Chung;Keum, Kyung-Soo;Eom, Dong-Myung
    • Journal of Korean Medical classics
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    • v.22 no.3
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    • pp.211-225
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    • 2009
  • Soyosan is one of the most famous prescription in Oriental Medicine. It was showed for the first time in "Hwajegukbang(和劑局方)", the book of prescriptions, published in Song Dynasty, 1078. However, Soyosan did not include Maekmundong. Heojun as a author, made "Dong-uibogam" in 1613. Soyosan of "Dong-uibogam" had Maekmundong. In this study, I focused on how to get Maekmundong in "Dong-uibogam". Nonetheless, Soyosan originally didn't have Maekmundong. Soyosan and Maekmundong combined easily when Soyosan controlled disease related with Heat[熱]. Therefore, I suggest author or editor might put Maekmundong to Soyosan in "Dong-uibogam".

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Comparison of Nerve Growth Factor Induction by Butanol Fraction of Liriope platyphylla and Ophiopogon japonicus (산지별 맥문동 부탄올분획물의 신경성장인자 유도 효과에 관한 비교)

  • Kang, Tong-Ho;Kim, Sun-Yeou
    • Korean Journal of Pharmacognosy
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    • v.39 no.2
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    • pp.75-79
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    • 2008
  • Nerve growth factor (NGF) is a protein plays a major role in the development and maintenance of central and peripheral nervous system. Recent data suggest that reduced availability of NGF may play a significant role in the pathogenesis of diabetic $polyneuropathy.^{1)}$ In our previous study, steroidal saponin from Liriope platyphylla showed neurotrophic effect by stimulation of NGF synthesis and activation of tyrosine kinase $signaling.^{2)}$ In this study, we examined the neurotrophic effect of Liriope platyphylla (LP); which was from Mylyang(MYL) and Cheongyang(CHE), and Ophiopogon japonicus (CHI) on in vitro and in vivo model for the comparison of their NGF induction. We quantitatively analyzed spicatoside A in the LP and CHI by HPLC. And we investigated the correlation between the contents of spicatoside A and NGF induction efficacy on PC 12 cells and mouse serum. These results suggest that spicatoside A may enhance NGF induction in animal model.