• Journal of the korean veterinary medical association
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• v.32 no.4
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• pp.206-219
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• 1996

동물의 전염성 해면형 뇌증에는 양과 염소의 스크래피, 사슴과 엘크의 만성소모형, 밍크의 전염성 밍크 뇌증, 소 및 소과 야생동물의 소 해면형 뇌증 그리고 고양이의 고양이 해면형 뇌증등이 알려져 있다. 전염성 해면형 뇌증의 원인은 알려져 있지 않으며, 스트레인간의 차이는 숙주의 프리온 유전자에 있어서의 대립유전자의 차이에 의존되는 것으로 추정되고 있다. 이러한 동물의 전염성 해면형 뇌증들은 우리나라에서의 발생보고가 없는 해외 가축전염병이며 현재 영국에서 문제되고 있는 소 해면형 뇌증 즉 일명 광우병은 영국에서 1986년 최초로 확인된 새로운 가축전염병으로서 사람의 크로이츠휄트-야콥병과의 어떤 연관 가능성 때문에 수의학계의 관심의 대상이 되고 있는 질병이다. 영국정부 보건장관 스티픈 도렐은 최근(1996년 3월 20일)에 과거 10년 동안 영국의 소에 감염되어 온 소 해면형 뇌증이 사람의 희귀한 뇌 질환인 크로이츠휄트-야콥병의 새로운 스트레인과 관련성이 있는 증거가 있을 수 있는 것으로 과학자문위원회가 믿고 있다고, 영국하원에서 보고한 바 있다. 한편, 영국의 농업장관 더글러스 호그는 영국에서 30개월 이상된 소를 도살할 때에는 모든 뼈를 제거하여야 하며, 모든 포유동물의 조직은 농업용 사료로 사용해서는 아니된다는 새로운 규정을 공표하였다. 그러나 영국의 쇠고기는 안심하고 먹을 수 있다고 발표하면서 만일 문제가 된다면, 영국에서 사육하는 1천 1백만 마리의 소를 전부 도살할 용의가 있다고 하였다. 이러한 영국정부 견해는 다음 날 CNN News 등 세계 각 매스컴을 통하여 보도되었으며, 아직까지 과학적인 증거가 확립된 바는 없지만, 수의학이나 의학적인 사실 확인의 여부를 떠나, 사회 경제적인 문제로 큰 놀라움과 많은 의문사항을 남겨둔 채, 영국산 소와 쇠고기의 수입금지 조치 등 국제적인 문제로 확대되었다. 본편에서는 동물의 전염성 해면형 뇌증에 대하여 종합적으로 고찰해 보고자 한다.

• Journal of the Korea Convergence Society
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• v.8 no.1
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• pp.13-18
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• 2017

As the convergence technology is developing rapidly and the portable mobile devices are spreading in ubiquitous smart healthcare, users were able to get medical information easily through the smart health platform. According to such rapid industrialization, wellness care, aging society, information society, changes in disease aspects and life style, user-centered healthcare, and health promotion contents are being offered. In this study, we proposed the mining based mental health and blood pressure management service for the smart health. The proposed method provides the mental health management service and the blood pressure management service for chronic disease patients within the mining based smart health platform. Users receive optimized healthcare services regardless of time and place in the PHR based smart health platform. For the performance evaluation of the proposed mining based mental health and blood pressure management service, F-measure verification are conducted.

• The Journal of the Korea Contents Association
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• v.17 no.6
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• pp.551-560
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• 2017

This study is aimed at finding plans to enhance life satisfaction of elderly people with disability. For this, it analyzed the influence of economic characteristics and health characteristics upon life satisfaction, as well as a mediating effect of self-esteem. This study utilized data from the $7^th$ Panel Survey of Employment for the Disabled(PSED). The results are as follows, First, life satisfaction was high in the case of being employed and when old-age preparation was ready, current status of health, whether or not they need help in their daily life, chronic disease. Second, the mediate effect of self-esteem was analyzed for the influence of the plan for old age, good health condition and other's help in daily life upon life satisfaction. That is, those enhanced the self-esteem and it played an important role to improve life satisfaction. Based on such study results, this study recommends a number of the policy suggestions.

• The Journal of the Korea Contents Association
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• v.5 no.6
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• pp.230-237
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• 2005

In this paper, we are suggested a method that's a major topics in sports medicine. It is disease control, control and management of chronic degenerative disease, and promotion of health. We are analyze physical activity to scientific and quantitative a trainee at Wu-Shu gymnasium, for a suggested method. We are measured a quantity of physical activity by SenseWear-PRO2-Armband which develop body-media company. Armband include to skin temperature sensor, near-body temperature sensor, accelerometer, heat flux sensor, galvanic skin response sensor. Acquired data was recorded to storage in Armband. We are analyzed using InnerView Wearer Software in the Stored data to skin temperature, calorie expenditure, quantity of physical activity. The result of this analyzed, we are know that a man of long-term exercise expenditure energy at short time and if liveliness of physical activity was Increase in expenditure energy with increase skin temperature. Also, we are know that the heat flux after increase expenditure energy with increase skin temperature. And, know that GSR was not affected a factors that physical activity, expenditure energy, increase skin temperature, and others.

• Journal of the Korea Convergence Society
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• v.2 no.4
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• pp.47-52
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• 2011

Periodontal disease is a common inflammatory disorder that is being considered as a risk factor for atherosclerotic complication. Recent epidemiological evidence also supports that its potential association with increased blood pressure levels and hypertensive prevalence. Data from cross-sectional studies suggest that in hypertensive patients periodontal disease may enhance the risk and degree of target organ damage. So dental infections have been associated with cardiovascular diseases. There are potential pathophysiologic links between hypertension and periodontits. The role of the inflammatory pathway include C-reactive protein(CRP). CRP is an inflammatory mediator that has been shown to predict the development of hypertension independently of baseline BP and traditional risk factors, has been consistently reported as at least mildly elevated in patients with periodontal disease. Reactive oxygen species produced by locally infiltrating neutrophils participate in periodontal tissue destruction. Periodontits can lead to inflammatory responses in the atrial myocardium, which disturbs the structural and electrophysiologic properties of the atrium and facilitates atrial fibrillation in the animal experiment.

• Korean Journal of Psychosomatic Medicine
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• v.12 no.2
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• pp.103-121
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• 2004

Conversion disorder and factitious disorder should be ruled out before making diagnosis of malingering. For this work, inspection of patient's behavior along with complete neurological examinations, psychological tests, and meticulous psychiatric interview are necessary. Facial expression test, thermography, dynamometry were failed differentiating conversion disorders to the malingered pain and motor symptoms, however, controlled diagnostic block showed positive result partly in patients with regional or cervical pain syndrome. Chronic pain patients who are related to the process of litigation encounter stressful life situations which lead them into various neurobehavioral and psychosocial complications. Most of suspected malingered patients would not revealed pure form rather mixed with factitious and/or conversion features. At the time of increasing number of chronic patients associated with traffic accidents or industrial injuries who are involved in litigation, psychiatrist are needed sharp eyes and tenacity for evaluating malingering or medically unexplained symptoms.

• Journal of Ginseng Research
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• v.33 no.1
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• pp.1-7
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• 2009

Clinical and animal studies have shown that free radical overload is an important cause for a variety of diseases. Although ginseng has been recognized as antioxidant, how it modulates anti-oxidative process at the molecular level remains unknown. Free radical production is induced by tumor necrosis factor-$\alpha$ (TNF-$\alpha$) under the stress condition, and (TNF-$\alpha$) release is activated by TNF-$\alpha$-converting enzyme (TACE). Since TACE inhibitor is also well known for anti-inflammatory agent, ginseng seems to show anti-oxidative activity by repressing TACE pathway. Further studies on signal transduction would be warranted to elucidate molecular action mechanisms of ginseng on anti-oxidation and anti-inflammation.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2011.10a
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• pp.5-5
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• 2011

최근에 고령화 사회에 접어들면서 건강하게 활동하며 수명을 다하는 것이 중요한 연구과제가 되고 있다. 이 때문에 영양, 운동, 스트레스, 환경 등과 관련하여 암, 당뇨병, 고혈압, 비만, 동맥경화 등 생활습관병의 극복이 사회문제가 되고 있는 실정이다. 지금까지 고려인삼의 대표적인 동물실험 및 임상학적 연구결과를 종합하여 보면 성인의 난치성 만성질환에 대해서 치료제보다는 질병을 예방하고 회복촉진에 보다 큰 효과 있음을 확인할 수 있다. 이는 인삼이 식품과 의약품의 중간에 위치한 식품의약품(Nutraceutical)의 용도로 활용할 수 있음을 시사한다. 현재까지 인삼제품에 표시되는 기능성의 내용은 약 3,000여편 이상의 약리효능에 관련된 논문이 발표되었다 하더라도 "피로회복, 면역력 증진, 혈소판 응집 억제를 통한 혈액흐름에 도움이 됩니다"이며 이외의 기능성 표시는 현재로서 원칙적으로 불가한 것으로 되어 있다. 그러나 시험물질의 규격화 및 임상시험의 검토기준을 만족시키는 과학적 자료제출에 의한 개별 평가 후 표시내용의 확대가 가능하다. 고려인삼의 다양한 성분 중 ginsenoside는 주요 약효성분으로 인정을 받고 있으며 현재 품질관리의 지표성분으로 활용되고 있다. 이러한 개별 ginsenoside의 약리작용을 보면 서로 유사 또는 상반된 효과를 보여주는 성분들이 공존하고 있어 인삼의 다양한 약리효과와 일맥상통하는 것으로 보고되고 있다. 아울러, ginsenoside는 인삼의 부위 별로 현격한 차이를 보여주기 때문에 소재의 규격화는 매우 중요하다고 판단된다. 따라서, 인삼제품 개발의 가장 중요한 조건은 의약품에 가까운 기능성식품으로 세계적인 제품을 만들기 위해서는 표준화가 선행되어야 한다. 이와 같은 조건을 잘 충족시키는 제품이 스위스 "파마톤의 진사나(백삼추출물, G115)" 제품으로 생각할 수 있다. 따라서, 고려인삼의 수출시장 확대 및 세계적인 제품을 위해서는 진사나에 필적할 수 있는 새로운 홍삼의 표준화된 추출물을 도출하는 것이 무엇보다 급선무라 생각한다. 아울러 고려인삼의 특장점 발굴을 위한 표준화 된 추출분획물, 활성성분 및 효능과 연계한 새로운 고부가가치 창출제품(식품/의약품)개발에 주력해야 할 것이다.

• The Journal of Society for e-Business Studies
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• v.22 no.1
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• pp.37-49
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• 2017

In order to maximize the efficiency and the quality of care in a hospital, hospitals in general operate by appointments. Patient no-shows or missed appointments waste the time of staffs who prepare for appointments, deprive patients of needed care, and increase burden on clinic capacity. The purpose of this study is to examine the importance and significance of factors that affect patient no-shows. The actual data of 50,000 outpatient appointments is compiled and analyzed from a VAMC in the United States with aims to identify the factors that contribute to outpatient no-shows and to draw meaningful implications. Random forest along with logistic regression analysis identify the factors affecting no-shows; appointment leadtime, show-up rate, travel distance, no-show rate in previous period, patient age, severity, complexity of disease, chronic pain, depression, drug dependence. The appointment leadtime, show-up rate, travel distance and previous no-show rate can be improved by enhancing SMS pre-notification and by improving afterwards telephone counseling. For other factors, it needs to study on the service differentiation with the characteristics of each patient group.

• Journal of the Korea Society of Computer and Information
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• v.17 no.1
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• pp.41-52
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• 2012

According to 2005 Korea National Health and Nutrition Survey, it has been reported that 32.9% men and 31.8% women have Metabolic syndrome among the population of age 30 and over. The importance of prevention and management is being emphasized in Metabolic syndrome which is a complex disease related to various generic and environmental factors like other chronical disease. In this study we suggest an service based on the data using the system architecture, ontology and Jena2.0 inference engine and organizing the disease-related guideline. The study also arrives at the result through proper interpretation and reasoning process using health management service model based on ontology. The accuracy according to the situation was tested and 930 data samples were selected and experimented. We drew a conclusion that the much personalized data is available, the more personalized services are possible. Since the risk factors of Metabolic syndrome are various, it would be effective to suggest customized services based on various personalized data.