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Hypofractionated Radiation Therapy for Early Glottic Cancer - Preliminary Results - (초기 성문암 환자에서의 소분할 조사법을 이용한 방사선치료 - 예비적 결과 -)

  • Wu Hong-Gyun;Hong Semie;Shin Seong Soo;Park Charn Il
    • Radiation Oncology Journal
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    • v.19 no.4
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    • pp.301-305
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    • 2001
  • Purpose : This study was peformed for the evaluation of the feasibility and toxicity of hypofractionated radiation therapy for early glottic cancer Methods and Materials : From February 1999 to February 2000, 20 patients with Histologically confirmed Stage I, II glottic cancer were enrolled into this study. There were 18 males and 2 females, the median age of the patients was 59 years. The distribution of stage distribution was as fellows; T1aN0-16 patients, T1bN0-1 patient, T2N0-3 patients. Eighteen patients underwent laryngomicroscopic biopsy only, and two patients underwent laser cordectomy. All patients received radical radiation therapy (2.5 Gy per fraction, 24 fractions, total 60 Gy). Median duration of treatment was 36 days (range $31\~45\;days$). Results : Radiation therapy were well tolerated. Most common acute reactions were odynophagia and hoarseness, and these reactions resolved after radiation therapy. There were one case of RTOG grade 3 odynophagia $(5\%)$, six cases of grade 3 hoarseness $(30\%)$. Response of radiation therapy was evaluated one month after completion of treatment. All patients revealed complete response. During follow up, total three cases of treatment failure were detected. two cases were local recurrence in 10 and 13 months of radiation therapy and one case was local recurrence and distant metastasis in 2 months of radiation therapy. Conclusion : This hypofractionated radiation therapy schedule was feasible and effective for control of early glottic cancer But longer follow up time would be required to assess the long-term disease control and the late complication by shortening radiation therapy duration.

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증착 환경 변화에 따른 인이 첨가된 ZnO 박막의 물성연구

  • Jeong, Yeong-Ui;Lee, Seung-Hwan;Hwang, Seon-Min;Jo, Chang-U;Bae, Jong-Seong;Park, Seong-Gyun
    • Proceedings of the Korean Vacuum Society Conference
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    • 2012.08a
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    • pp.299-299
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    • 2012
  • 투명전도산화물 박막은 디스플레이, 태양전지, 압전소자 등 다양한 응용분야에 많이 이용되고 있는 소재이다. 그 중에서 현재 산업에서 활용 빈도가 높은 투명전도막의 재료는 ITO를 기반으로 하는 물질이다. 하지만 인듐의 높은 생산단가와 플라즈마 노출시 열화로 인한 문제점 때문에 기존의 ITO를 대체하기 위한 새로운 재료에 관심이 증대되고 있다. 본 연구에서는 대표적인 ITO 대체 물질 중의 하나인 ZnO 박막에 대해서 증착환경변화에 따른 물성변화를 조사하였다. 먼저 대기중에서 안정화된 ZnO 박막을 얻기 위해서 인(P) 2% 첨가된 ZnO 세라믹을 고상반응법으로 제작하고, 펄스레이저 증착법을 이용하여 Al2O3(0001)기판에 산소분압을 30~150 mTorr로 변화를 주어 P-ZnO 박막을 제작하였다. 이 때 증착온도는 $400^{\circ}C$로 고정하였다. X선 회절 결과로부터 산소분압에 상관없이 ZnO (002)방향으로 증착되었다. 하지만 결정립의 크기는 산소분압이 증가하면서 줄어들고, ZnO (002)피크로부터 얻어진 격자상수(c-축)는 벌크 값에 가까워짐을 알 수 있었다. 하지만 P첨가로 인해서 박막의 격자상수는 순수한 ZnO 벌크 값 보다 큰 것으로 알 수 있다. 산소분압 변화에 따른 P-ZnO 박막의 산화 상태는 X-선 광전자 분광기를 이용하여 측정하였다. 그 결과 산소 core-level의 스펙트럼은 자연산화, 산소 vacancy, Zn-O 결합으로 구성되어짐을 알 수 있었다. 산소분압이 증가하면 Zn-O 결합은 증가하지만 산소 vacancy는 감소함을 알 수 있었다. 전기적 특성 결과 P-ZnO 박막은 30 mTorr에서는 n형 반도체 특성, 100 mtorr에서 p형 반도체의 특성이 나타내었고, 산소분압이 증가하면 다시 n형 반도체 특성을 나타냄을 알 수 있었다. 광학적 특성 결과 P-ZnO 박막은 산소분압에 상관없이 가시광선 영역에서 80%이상의 투과율을 나타내었으며, 산소분압이 증가할수록 에너지 갭이 증가하였다.

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Tin Germanium Sulfide Nanoparticles for Enhanced Performance Lithium Secondary Batteries (고성능 리튬 이차 전지를 위한 황화 주석 저마늄 (SnxGe1-xS) 나노입자 연구)

  • Cha, E.H.;Kim, Y.W.;Lim, S.A.;Lim, J.W.
    • Journal of the Korean Electrochemical Society
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    • v.18 no.1
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    • pp.31-37
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    • 2015
  • Composition-controlled ternary components chalcogenides germanium tin sulfide ($Sn_xGe_{1-x}S$) nanoparticles were synthesized by a novel gas-phase laser photolysis reaction of tetramethyl germanium, tetramethyl tin, and hydrogen sulfide mixture. Subsequent thermal annealing of as-grown amorphous nanoparticles produced the crystalline orthorhombic phase nanoparticles. All these composition-tuned nanoparticles showed excellent cycling performance of the lithium ion battery. The germanium sulfide nanoparticles exhibit a maximum capacity of 1200 mAh/g after 70 cycles. As the tin composition (x) increases, the capacity maintains better at the higher discharge/charge rate. This novel synthesis method of tin germanium sulfide nanoparticles is expected to contribute to expand their applications in high-performance energy conversion systems.

A Study for The X-ray Image Acquisition Experiment Using by Gas Electron Multipliers (기체전자증폭기를 이용한 X-선 영상획득실험에 관한 연구)

  • 강상묵;한상효;조효성;남상희
    • Journal of Biomedical Engineering Research
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    • v.24 no.2
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    • pp.83-89
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    • 2003
  • The gas electron multiplier placed in the drift volume of conventional gas detectors, is a conceptually simple device for producing a large gas gain by concentrating the drift electric field over a very short distance to the point that electron avalanching occurs(〉 10$^4$ V/cm), greatly increasing the number of drifting electrons. This device consists of a thin insulating foil of several tens of urn in thickness. covered on each side with a thin metal layer(Cu), with tiny holes, usually 100 ${\mu}{\textrm}{m}$ or less in diameter. and with a spacing of 100-200 ${\mu}{\textrm}{m}$ through the entire foil. perforated by using chemical etching or high-powered laser beam technique In this study, we have investigated its operating properties with various experimental conditions, and demonstrated the possibility of using this device as a digital X-ray imaging sensor, by acquiring X-ray images based on the scintillation properties of the gas electron multiplier with standard CCD camera.

Thermal conductivity of acrylic composite films containing graphite and carbon nanotube (흑연과 탄소나노튜브를 함유한 아크릴 복합체 박막의 열전도도)

  • Kim, Jun-Yeong;Gang, Chan-Hyeong
    • Proceedings of the Korean Institute of Surface Engineering Conference
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    • 2016.11a
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    • pp.185-185
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    • 2016
  • 아크릴계 수지(resin)에 인조 흑연과 탄소나노튜브(carbon nanotube)를 1:1 비율로 혼합한 충전제(filler)와 용제(solvent) 및 기타 첨가제(additives)를 혼합하여 방열도료를 제조하여 수직방향 열전도도를 상온에서 평가하였다. 충전제의 함량을 1, 2, 5 중량 %로 변화시키며 원료들을 준비하여 교반기로 혼합한 뒤 3단 롤 밀(three roll mill)로 분산공정을 진행하여 3 종류의 도료를 제조하였다. 제조한 도료를 가로 11 mm, 세로 11 mm, 두께 0.4 mm의 Al 5052 알루미늄 기판에 스프레이 코팅 방식으로 도포한 후 $150^{\circ}C$에서 30분 동안 열경화 건조 과정을 거쳐 샘플을 제작하였다. 측정 시료의 형상은 대략적으로 Fig. 1과 같다. 열전도도는 식 $k={\alpha}{\cdot}C_p{\cdot}{\rho}$를 사용해서 계산된다. 여기서 k는 열전도도($W/m{\cdot}K$), ${\alpha}$는 열확산계수($mm^2/s$), $C_p$는 비열($J/kg{\cdot}K$), ${\rho}$는 밀도($g/cm^3$)를 나타낸다. 열확산계수는 독일 NETZSCH 사의 Laser Flash Analysis 장비(모델명 LFA 457)를 사용하여 측정하였는데, 기판 뒤쪽에서 레이저를 조사하고 도료층 전면에서 적외선 온도센서를 통해 시간에 따른 온도 상승곡선을 구한 후, 두 물체의 계면에서의 접촉 열저항(contact thermal resistance)을 감안하여 장비에 내장되어 있는 소프트웨어로 열확산계수가 계산된다. 비열은 같은 회사의 DSC(Differential Scanning Calorimetry) 200 F3 장비를 사용해 측정했으며, 밀도는 부피와 질량을 측정한 값을 이용하여 계산하였다. 도료를 도포하지 않은 bare Al plate에 대해서는 쉽게 열확산계수, 비열, 밀도를 측정하여 열전도도를 구할 수 있다. 도료가 코팅된 샘플에 대해서는 도료층을 일부 떼어내 비열을 측정하고, 밀도를 구한 후, 도료층의 열전도도가 2-layer 법으로 장비 내장 소프트웨어로 계산된다, 이때 Al 기판의 열확산계수, 비열, 밀도는 미리 측정한 bare Al plate의 값을 적용하였다. 실험 결과를 Table 1에 정리하였다. 흑연과 탄소나노튜브를 혼합한 충전제를 함유한 아크릴 복합체 박막에서 측정된 열전도도는 보통 고분자 재료의 열전도도 값의 상한 영역에 육박하는 값이며, 충전제 함량이 증가할수록 열전도도가 증가하는 경향을 보이고 있다.

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Aggregation of Partially Quarternized Poly(4-vinylpyridine) with Anionic Surfactant Sodium Dodecvl Sulfate (부분적으로 4차아민화된 폴리(4-비닐피리딘)과 음이온 계면활성제인 도데실 황산 소듐과의 응집체 형성)

  • 김용철;박일현;심후식;최이준
    • Polymer(Korea)
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    • v.28 no.2
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    • pp.154-161
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    • 2004
  • Modified poly(4-vinylpyridine) was obtained by partial quarternization of nitrogen atoms in pyridine rings of poly(4-vinylpyridine) with methyl group. By means of laser light scattering and fluorescence, it was found that this modified polymer chains were aggregated in the aqueous solution and its structure was core-shell type. The hydrophobic parts of the chains were densely condensed in core part and the hydrophilic part of quarternized amino with positive charge formed the shell part. In the mixed system of modified poly(4-vinylpyridine) and anionic surfactant, sodium dodecyl sulfate, it was observed that a critical aggregation concentration existed and that this critical concentration was suddenly decreased above 0.1 M NaCl. The size change of aggregates was also investigated by dynamic light scattering while sodium dodecyl sulfate was added into polymer solution upto the critical aggregation concentration.

Fabrication and Characterization of High Temperature in-situ Ramp-edge Type Josephson Junction (고온초전도체 in-situ ramp-edge 형태의 조셉슨 접합 제작 및 특성)

  • Hur, Yun-Sung;Kim, Jin-Tae;Hwang, Yun-Seok;Lee, Sun-Gul;Park, Gwang-Seo;Kim, In-Seon;Park, Yong-Ki;Park, Jong-Chul
    • Korean Journal of Materials Research
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    • v.8 no.3
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    • pp.263-267
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    • 1998
  • In this study, we have fabricated in-situ multilayer $YBa_2Cu_3O_{7-\delta}$/$SrTiO_{3}$/$YBa_2Cu_3O_{7-\delta}$ ramp edge type junctions by using a metal mask and pulsed laser deposition method and studied the junction properties. The junctions showed RSJ-like I-V characteristics. The normal state junction resistance R, of $18 \omega$ was nearly constant with temperature. The dc-SQUID sensors fabricated with the junctions show a sensitivity that transfer function dV/$d\Phi$)~$22\mu$V/$\Phi_{0}$, indicating that the in-situ ramp edge type junction is potentially useful for sensor application.

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Effects of Intravenous He-Ne Laser Irradi on Meridian-Heart·Circulation CMP and Hyperlipidemia (정맥혈관내(靜脈血管內) 헬륨-네온 레이저 조사(照射)가 메리디안 심(心)·순환(循環) 대표점(代表點)과 고지혈증(高脂血症)에 미치는 영향(影響))

  • Ahn, Soo-gi;Lee, Sam-ro;Hwang, Woo-jun
    • Journal of Sasang Constitutional Medicine
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    • v.10 no.1
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    • pp.269-284
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    • 1998
  • The purpose of this study was to investigate the effect of ILIB(Intravenous Laser Irradiation of blood) on Meridian-Heart Circulation CMP and Hyperlipidemia. Circulatory symptom of 20 patients was treated with ILIB. After 10 times' treatment, changes of total cholesterol, HDL-cholesterol, triglyceride and Meridian-Heart Circulation CMP value were observed. The results were as follows : 1. In observation of Meridian-Heart Circulation CMP value, significant increase was observed in both pre-ID generation and post-ID generation. So, distinctive observation between pre-ID generation and post-ID generation became not relatively significant. 2. In observation of Meridian-Heart Circulation CMP value, significant increase was observed in both left and right. So, distinctive observation between left and right became not relatively significant. 3. In observation of Meridian-Heart CMP value, significant increase was not observed in control group, but significant increase close to normal value was observed in treatment group after treatment of Intravenous He-Ne Laser Irradiation. 4. In observation of Meridian-Circulation CMP value, significant increase was not observed in control group, but significant increase close to normal value was observed in treatment group after treatment of Intravenous He-Ne Laser Irradiation. 5. In concentration of plasma total cholesterol and plasma triglyceride, significant decrease was not observed in control group, but significant increase was observed in treatment group after treatment of Intravenous He-Ne laser Irradiation. 6. Significant concentration change of plasma HDL-cholesterol was not observed in both control group and treatment group. From above results, it was thought that Intravenous He-Ne Laser Irradiation was significant effect on heart circulatory system in human body.

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Atomic Coherence Spectroscopy in the Paraffin Coated Rb Atom Vapor Cell (파라핀 코팅된 Rb원자 증기 셀에서 원자결맞음 분광)

  • Lee, Hyun-Joon;Yu, Ye-Jin;Bae, In-Ho;Moon, Han-Seb
    • Korean Journal of Optics and Photonics
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    • v.19 no.4
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    • pp.334-340
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    • 2008
  • We investigated the electromagnetically induced transparency (EIT) and the Hanle spectrum in a paraffin coated Rb vapor cell. The EIT spectrum was observed in the $F_g=2$, $3{\rightarrow}F_e=3$ transition of the $^{85}Rb$ $D_1$-line by using two independent external cavity diode lasers, and the Hanle spectrum was observed by using one external cavity diode laser in the $\Lambda$-type scheme between the Zeeman sublevels of the $F_g=2{\rightarrow}F_e=1$ transition of the $^{87}Rb$ $D_1$-line. In the Hanle spectrum, we could observe the dual-structured spectrum in the paraffin coated vapor cell. We investigated the dual-structured lineshape by applying an external magnetic field, and varying the direction of the magnetic field. The narrow linewidth of dual-structured EIT was measured to be approximately 200 Hz.

Fabrication and Electromechanical Behaviors of a SWNT/PANi Composite Film Actuator (탄소나노튜브/도전성폴리머 복합재 엑츄에이터의 제조 및 특성실험)

  • Zhang, Shuai;Kim, Cheol
    • Composites Research
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    • v.19 no.5
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    • pp.7-11
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    • 2006
  • The improved SWNTs/PANi composite actuator films applicable to an artificial muscle were fabricated successfully using a new process of manufacture that consists of 90% pure single-walled carbon nanotubes (SWNT) and chemical polymerization. PANi is electrically conducting polyaniline polymer. The conductivities of the composite SWNTs/PANi film-type actuators and the pure PANi films fabricated were measured as 56.15 S/cm and 17.38 S/cm, respectively, by the 4-prove method. The conductivity of the composite actuator is 3.2 times higher than the pure PANi film. The fabricated composite actuator showed higher conductivity than any other similar ones. The quality of samples was investigated by an electron scanning microscope (SEM). To measure the actuating strains, a specially designed beam balance apparatus was developed and strains of the composite actuators was measured by a laser displacement sensor subjected to electric currents. During the operation, the sample was soaked in the $NaNO_3$ solution and the sine-wave voltage in the range of $+1V{\sim}-1V$ was applied. The length of the composite actuator changed from $l_0=12.690$ mm to $l_1=12.733$ so that the change of length was l=0.043 mm and the strain was 0.34 %. This is a very high strain for this kind of a composite actuator. Other result reported by Tahhan showed 0.23 % strain, so that the present result is improved by 48%.