• Korean Journal of Clinical Laboratory Science
• /
• v.51 no.3
• /
• pp.329-335
• /
• 2019

Annually, millions of children die from respiratory virus infections. Human rhinovirus (HRV) is a causative agent of severe respiratory infections in young, elderly, and asthmatic patients with weak immunity. In this study, 9,010 respiratory virus specimens were collected from January 2012 to December 2018 at Dankook University Hospital, Cheonan and examined by real-time reverse transcription polymerase chain reaction. Twelve respiratory viruses were detected. The mean detection rate was 21.3% (N=1,920/9,010), and the mean age of HRV-positive patients was 6.5 years (median age: 1.6 years, range: 0.0~96.0). The detection rate was the highest in July (32.4%) and the lowest in February (8.3%). When the detection rate was analyzed by age group, the detection rate was the second highest in patients aged 10~19 years. The co-infection rate of HRV was 35.3%, and the most common combination was with Adenovirus. Respiratory virus infections are known to occur in children and elderly people with weak immunity. However, in this study, the detection rate was second highest in patients aged 10~19 years. Indeed, the detection rate in this age group was more than 15%, except in January and February. These results suggested that steady-state studies on the infection patterns of HRV are required.

• Journal of Food Hygiene and Safety
• /
• v.34 no.3
• /
• pp.303-308
• /
• 2019

L-carnitine is found in high levels in muscle tissues. It has been developed as a nutrient and dietary supplement, and also used as a therapeutic supplement in various diseases including type II diabetes, osteoporosis and metabolic neuropathies. However, it is not fully understood how it affects cellular mechanisms in colorectal cancer. Therefore, we attempted to determine the effect of L-carnitine in HCT116 human colorectal cancer cells. First, the HCT116 cells were exposed to L-carnitine for 24 hours at 0-40 mM, and then analyzed for cellular proliferation, oxidative stress and related mechanisms. In a MTT assay, L-carnitine inhibited cellular proliferation and induced reactive oxygen species (ROS) in HCT116 by DCF-DA analysis. To analyze the mechanism of L-carnitine in colorectal cancer cells, we performed a western blot analysis for pERK1/2 and pp38 MAP kinase. The western blot showed that L-carnitine significantly increased protein levels of pERK1/2 and pp38 compared with control. Taken together, we found that L-carnitine has anti-proliferative function via increased ROS and activation of ERK1/2 and p38 pathway in HCT116. These findings suggest that L-carnitine may have an anti-proliferative role on colorectal cancer.

• The Journal of Korean Academy of Prosthodontics
• /
• v.57 no.1
• /
• pp.81-87
• /
• 2019

Patients with Down's syndrome have several dental complications such as small teeth caused by underdevelopment of dentin and enamel, periodontitis, agenesis of teeth, prolonged retention of primary teeth and malocclusion due to narrow palate. Removable denture with maxillary double crowns would be a good treatment option to solve the problems of the patient with Down's syndrome. Double crowns compensate the insufficient support and retention of denture and easily solve the cross bite problem. Double crowns also allow easy repair of denture in case of abutment teeth extraction. In this case, 26-year-old female patient with Down's syndrome and dental phobia had small number of teeth with enamel hypoplasia, prolonged retention of primary teeth and dental cross bite. Prosthetic treatment was done using removable denture with double crowns in the maxilla. In the mandible, teeth preparation was done on enamel margin without anesthesia. Anterior laminate and posterior complete zirconia crown restorations were performed. As a result, the cross bite was effectively corrected by denture with double crowns. Pronunciation and appearance were also improved without extraction of teeth and dental anesthesia.

• Journal of the Korean Institute of Traditional Landscape Architecture
• /
• v.36 no.4
• /
• pp.28-38
• /
• 2018

The purpose of this study is to clarify what is the unique garden making methods of Enshu Kobori by surveying and analyzing that existing garden of Enshu Kobori is different from the existing Japanese garden that had been built up to such a period. Enshu Kobori breaks away from the conventional frame that was established with the gardens of existing Karesansui style(枯山水樣式) with the materials of rocks and sands. Enshu Kobori is produced to make harmony with the rocks by trimming the Rhododendron indicum and this type of making method of Enshu was originated from the aesthetic principle of kireisabi. Due to this type of cause, the garden of Enshu Kobori displays splendid and yet a simple beauty of gardening. With respect to the establishment of a garden unique to Enshu Kobori as such, it seemed to have the cultural background expanded with the cultural perception and official family class of the edo period where it strived for new things. Therefore, Enshu Kobori was designed as the ornament-oriented garden rather than the garden that requires direct ceremonial act. The subject sites for this study are Raikyuji, Daichiji, Shodenji, Nanzenji Hojo and Konchiin as intended by Enshu Kobori. Contents of the study contemplate the location of garden, factors to introduce the garden, structure of garden, background of garden, use of stones, plants and scenic views to clarify the uniqueness of the Enshu Kobori garden.

• Journal of Convergence for Information Technology
• /
• v.9 no.5
• /
• pp.158-164
• /
• 2019

Recently many studies to reduce the noise of dental hand piece which generate inevitably mechanical sound to offend to the ear of a patient have been spotlighted. Generally, methods of adding a sound absorbing material inside the exhaust valve, air pump of machine or automobile are widely reported as optimal way to reduce the mechanical noise. In this paper we studied a new UV laser aided manufacturing of micro-porous structure of EPP substrate and applied dental hand piece to improve the efficiency of sound absorption. A lot of micro-sized pores were fabricated with UV laser processing on the surface of sliced EPP substrate. From fundamental experiments, more high-performance of micro-porous EPP substrate has finally demonstrated for sound-absorbing structure of the micro muffler inside dental hand piece, which actually has the excellent potential to apply a lot of potable machine.

• Journal of Convergence for Information Technology
• /
• v.10 no.12
• /
• pp.201-207
• /
• 2020

In this study, the practicality of unmanned aerial vehicle photography information was identified. Therefore, a total of four consecutive surveys were conducted on the field-level survey areas among the areas subject to photography using unmanned aerial vehicles, and the changes in crop conditions were analyzed using pictures of unmanned aerial vehicles taken during each survey. It is appropriate to collect and utilize photographic information by directly taking pictures of the survey area according to the time of the on-site survey using unmanned aerial vehicles in the field layer, which is an area where many changes in topography, crop vegetation, and crop types are expected. And it turned out that it was appropriate to utilize satellite images in consideration of economic and efficient aspects in relatively unchanged rice paddies and facilities. If the survey area is well equipped with systems for crop cultivation, deep learning can be utilized in real time by utilizing libraries after obtaining photographic data for a certain area using unmanned aircraft in the future. Through this process, it is believed that it can be used to analyze the overall crop and shipment volume by identifying the crop status and surveying the quantity per unit area.

• Journal of Life Science
• /
• v.31 no.3
• /
• pp.346-355
• /
• 2021

The purpose of this study was to evaluate the possibility that administration of Bacillus polyfermenticus KJS-2 (BP2), Bacillus mojavensis KJS-3 (Moja3), and their mixtures could control serum lipid levels. We observed changes in the blood cell level, metabolic function evaluation, and blood lipid levels after two weeks of oral administration of these microbial strains to hyperlipidemia-induced rats. Measurements of major cell changes in the white blood cells (WBC) indicated no significant effects due to the administration of the microbial strains. Platelet (PLT) levels decreased by 18.4% in the Triton WR-1339-treated group (NCON) and recovered to the control (CON) group levels in the positive control (PCON) group and the microbial strain-administered groups (p<0.05). No functional changes were observed in red blood cells (RBC) by Triton WR-1339-induced hyperlipidemia. The blood AST, ALT, BUN, and creatinine levels did not indicated effects on liver and kidney function, and all rats administered the microbial mixture recovered. The blood lipid levels in the microbe-treated groups indicated reduced levels of triglyceride (TG) and total cholesterol (TC), and increased levels of serum HDL cholesterol. The HMG-CoA inhibition rate of 7-O-succinyl macrolactin A (SMA) produced by BP2 showed similar activity at a concentration of 1,000 times lower than that achieved with atorvastatin. The administration of the microbial strains to the Triton WR-1339-induced rat model of hyperlipidemia resulted in reduced weight gain without affecting the food and water intake. Thus, blood circulation can be improved by controlling serum lipid levels by the combined administration of the BP2 and Moja3 microbial strains.

• The Journal of the Convergence on Culture Technology
• /
• v.7 no.1
• /
• pp.654-661
• /
• 2021

Air pollution caused by industrial development has become a level that can seriously threaten human health. In general, indoor air pollution is considered to be lower than outdoors, but modern people live indoors most of the time, thus it is essential to keep the indoor air quality comfortable in order to take care of one's own health and improve the quality of life. Therefore, the development of an indoor environment management platform using Internet of Things and data processing technology, which is currently drawing attention, is considered a very meaningful study. In this paper, we designed an IoT-based management platform that can remotely monitor and control indoor environments. In addition, the functions of the IoT terminal, gateway, and data server constituting the platform were implemented using open source and open libraries, and all functional operations were also verified. In particular, the IoT terminal and the gateway in this paper exchange data using BLE communication, so they can operate with relatively low power and since the gateway uses the BLE Advertising mode, it has the advantage of automatically recognizing IoT terminals that have not been previously configured.

• Food Science and Industry
• /
• v.50 no.2
• /
• pp.37-51
• /
• 2017

Food packaging strategies have steadily improved with increasing demand for improved food safety, convenience, and shelf life. The development of edible film has been hailed as a technology substituting packaging using synthetic plastics. There has been a surge for research to develop antimicrobial edible films and coatings that can increase microbiological safety while preserving foods. This review addresses recent results that are useful in advancing and extending research into antimicrobial edible films. In this review, we suggest the trend of the development of antimicrobial edible film/coatings by outlining edible film materials, antimicrobial substances, antimicrobial and physical properties of the films, commercial antimicrobial edible films, and methods to statistically predict the efficacy of antimicrobial edible film/coatings, reported in recent studies.

• 한국사회정책
• /
• v.24 no.1
• /
• pp.239-275
• /
• 2017

The purpose of this study is to explore what social workers experience and how they experience the needs of Meritocracy in the social welfare organization in the neoliberalism.. Therefore, in-depth interviews were conducted with 18 social workers, and I analyzed Colaizzi(1978) in a phenomenological method through collected research materials. As a result, the analysis is integrated in a total of four essential themes. According to the research results, the meritocracy - oriented phenomenon in the social welfare organization was 'paradox of Meritocracy'. Participants were buried in creating "nominal performance without any effectiveness" based on effectiveness and efficiency. Clients were instrumentalized in performance; moreover, they lost contact points with the field. Above all, there was "a reorganization of practices" that contradicted the original values of practice, in which the quality deterioration of service and the connection between organizations were weakened. In addition, the implementation of accountability of social welfare organization, which was intended by Meritocracy, has become a criterion for external evaluation, and the challenge of uncertain result has left a "rigid accountability without discretion." While participants were devoted to making a nominal performance, they failed to be guaranteed by the distinct characteristics of social welfare group. They experienced lost pride of the practitioner in the reality which contained the value of social welfare. However, in spite of this paradox of Meritocracy, participants demonstrated flexibility in order to preserve the original value and reached "a compromise with reality in the identity conflict." Based on the results of the research, I presented the discussion and policy directions.