• Journal of KIISE:Computer Systems and Theory
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• v.31 no.11
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• pp.626-634
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• 2004

In a client-server model, network server systems suffer from both heavy communication and computational loads. While communication channels become increasingly speedy, the existing protocol stack architectures still include mainly three performance bottlenecks of protocol stack processing, system call, and network interrupt overheads. To address these obstacles, in this paper we present a host-independent network system where a network interface card (NIC) is utilized in an efficient manner. First, by offloading network-related portion to the NIC, the host can fully utilize its processing power for other useful purposes. Second, it eliminates the system call overhead, such as context-switching and memory copy operations, since the host communicates with the NIC through its user-level libraries. Third, it a] so reduces the network interrupt operation count as the host handles the interrupt in a segment instead of a packet. The experimental results show that the proposed network system reduces the host CPU overhead for communication system by 68-71%. It also shows that the proposed system improves the communication speed by 11-83% under heavy computational and communication load conditions.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.19 no.1
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• pp.178-184
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• 2015

This paper proposes a hardware architecture for high performance Deblocking filter(DBF) in High Efficiency Video Coding for UHD(Ultra High Definition) videos. This proposed hardware architecture which has less processing time has a 4-stage pipelined architecture with two filters and parallel boundary strength module. Also, the proposed filter can be used in low-voltage design by using clock gating architecture in 4-stage pipeline. The segmented memory architecture solves the hazard issue that arises when single port SRAM is accessed. The proposed order of filtering shortens the delay time that arises when storing data into the single port SRAM at the pre-processing stage. The DBF hardware proposed in this paper was designed with Verilog HDL, and was implemented with 22k logic gates as a result of synthesis using TSMC 0.18um CMOS standard cell library. Furthermore, the dynamic frequency can process UHD 8k($7680{\times}4320$) samples@60fps using a frequency of 150MHz with an 8K resolution and maximum dynamic frequency is 285MHz. Result from analysis shows that the proposed DBF hardware architecture operation cycle for one process coding unit has improved by 32% over the previous one.

• Journal of radiological science and technology
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• v.35 no.2
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• pp.133-139
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• 2012

For the examination of nuclear medicine, myocardial scan is a good method to evaluate a hemodynamic importance of coronary heart disease. but, the automatized qualitative measurement is additionally necessary to improve the decoding efficiency. we suggests the creation of cardiac three-dimensional model and model of three-dimensional cardiac thickness as a new measurement. For the experiment, cardiac reduced cross section was obtained from SPECT. Next, the pre-process was performed and image segmentation was fulfilled by level set. for the modeling of left cardiac thickness, it was realized by applying difference equation of two-dimensional laplace equation. As the result of experiment, it was successful to measure internal wall and external wall and three-dimensional modeling was realized by coordinate. and, with laplace formula, it was successful to develop the thickness of cardiac wall. through the three-dimensional model, defects were observed easily and position of lesion was grasped rapidly by the revolution of model. The model which was developed as the support index of decoding will provide decoding information to doctor additionally and reduce the rate of false diagnosis as well as play a great role for diagnosing IHD early.

• Polymer(Korea)
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• v.28 no.5
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• pp.382-390
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• 2004

One of the significant natural bioactive materials is demineralized bone particle (DBP) whose has a powerful induce. of new bone growth. In this study, we developed the DBP loaded poly-lactide (PLA) and poly(L-lactide-co-glycolide) (PLGA) scaffolds for the possibility of the application of the tissue engineered bone. PLA/DBP and PLGA/DBP scaffolds were prepared by solvent casting/salt leaching method and were characterized by porosimeter, scanning electron microscopy. BMSCs were stimulated by osteogenic medium and characterized by histological stained Wright-Giemsa, Alizarin red, von Kossa, and alkaline phosphate activity (ALP). DBP impregnated scaffolds with BMSCs were implanted into the back of athymic nude mouse to observe the effect of DBP on the osteoinduction compared with control scaffolds. It can be observed that the porosity was above $90.2\%$ and the pore size was above 69.1$\mu$m. BMSCs could be differentiated into osteoprogenitor cells as result of wright-giemsa, alizarin red, von Kossa and ALP staining. In in vivo study, we could observed calcification region in PLA/DBP and PLGA/DBP groups, but calcification did not occur almost in control scaffolds. From these results, it seems that DBP as well as BMSCs play an important role for bone induction in PLA/DBP and PLGA/DBP scaffolds.

• Polymer(Korea)
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• v.29 no.5
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• pp.468-474
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• 2005

PLGA and PCL copolymers initiated by carbitol as drug carriers were synthesized by ring-opening polymerization of L-lactide (LA), glycolide (GA), and $\varepsilon-caprolactone(\varepsilon-CL)$. Implantable wafers were simply fabricated by direct compression method after physical mixing of copolymers and bovine serum albumin-fluorescein isothiocyanate (BSA-FITC) as a model protein drug. The release amounts of BSA-FITC from wafers were determined by fluorescence intensity using the fluorescence spectrophotometer. Also, the release behavior of BSA-FITC on wafers was controlled by adding the additives such as collagen, small intestinal submucosa (SIS), poly(vinyl pyrrolidone) (PVP), and poly(thylene glycol) (PEG). The wafer prepared by PLGA and PCL exhibited slow release within $10\%$ for 30 days. But, those prepared by a variety of additives exhibited the controlled BSA release patterns with a dependence on the additive contents. furthermore, the wafers containing natural materials such as collagen and SIS showed more zero-order release profile than that with synthetic materials such as PVP and PEG. It was confirmed that the release of BSA from implantable wafers could be easily controlled by adding natural additives.

• Polymer(Korea)
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• v.32 no.6
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• pp.529-536
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• 2008

We manufactured poly (L-lactide-co-glycolide) (PLGA) scaffolds impregnated demineralized bone particle (DBP) and hyaluronic acid (HA) by ice-particle leaching method and tested their ability of sustained release of brain derived neurotrophic factor (BDNF). BDNF (50 and 200 ng) mixed with PLGA, DBP/PLGA, HA/PLGA and DBP/HA/PLGA scaffold. The release profiles of BDNF from BDNF loaded scaffolds were assayed using ELISA. Morphological changes of scaffolds by BDNF release were also observed by SEM. BDNF stably and sustainedly released from DBP/HNPLGA than from PLGA and DBP/PLGA scaffolds. DBP/HA/PLGA scaffolds showed the great structural changes, which demonstrated BDNF release amount from DBP/HA/PLGA scaffolds were highest in all groups. We suggest that BDNF loaded DBP/HNPLGA scaffold would be very useful for nerve regeneration.

• Polymer(Korea)
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• v.37 no.6
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• pp.669-676
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• 2013

Demineralized bone particle (DBP) is a biomaterial used widely in the field of tissue engineering. In this study, in order to study the effect of DBP/poly(lactic-co-glycolic acid) (PLGA) scaffold on disc regeneration in vivo environment, we prepared the porous DBP/PLGA hybrid scaffold. Disc defect was induced by removing the nucleus pulposus tissue after incision the annulus fibrosus tissue in half and scaffolds were transplanted. After 1, 2 and 3 months later, the extracted discs were confirmed by collagen synthesis and glycosaminoglycan (sGAG). We conducted histology (H&E, Safranin-O, Alcian blue, Type I Collagen, Type II Collagen). From the results, it was confirmed that collagen and sGAG content were high in DBP/PLGA scaffold, and the regeneration of intervertebral disc was possible.

• Korean Journal of Microbiology
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• v.41 no.4
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• pp.300-305
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• 2005

A transcriptionally active fragment $(P_{19})$ isolated by utilizing the promoter-probe shuttle vector pSK1Cat was analyzed. By subcloning analysis, the 180 bp region $(P_{180})$ responsible for the activity was determined. Transcriptional fusion of the C. glutamicum metX gene to $P_{180}\;(P_{180}-metX)$ resulted in a 24-fold increase in MetX activity in a complex medium, while a 13-fold increase was observed with the $P_{tac}$ promoter. Additionally, the expression conferred by $P_{180}$ was not affected by methionine added to the growth medium, suggesting that the $P_{180}$ clone is useful for the deregulated expression of biosynthetic genes in C. glutamicum during amino acid fermentation. Introduction of $P_{180}-metX$ into a lysine-producing C. glutamicum resulted in the production of methionine to 0.8 g/l.

• Korean Journal of Organic Agriculture
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• v.7 no.1
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• pp.35-48
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• 1998

The total amount of dry matter for the green manure crops was great wheat> rye> barley> Italian ryegrass in that order. The green manure crope were verified to have the reducing effect of injury of successive croppingin peper, mainly reducing the occurance of the most important pepper disease, Phytophthora capsisi, and enhancing the pepper quality in the fruit length and diameter. The direct seeding using current commercial pepper variety was proved as not economical one. In the first year of compost application, the growth and yield of red pepper were rather somewhat decreasing compared with those of check plot applied with organic fertilizers. compst application increased the content of organic matter in soil, which suggested compost could be applied for the sustainable purposes. In preference analysis about taking the new technique, the smaller farmer's cultivation area the more they wanted to accept the LISA farming, compared with the conventional one, could be possible to save 12% in the inorganic fertilizer expenses but wasted 412% ant 163% in both organic fertilizer and operator labor expenses, respectively. At the same time, the LISA decreased 15% in production cost but increased 225% and 139% in organic fertilizer quantity and operator labor hours. Since there was a great deal of difference in technological and economic factors from two farming methods, LISA multi-goal decision modeling is further required.

• Journal of Internet Computing and Services
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• v.7 no.2
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• pp.81-92
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• 2006

Recently, the number of mobile phone and PDA users has been rapidly increased. Such monitoring and control applications as geographical and traffic information systems are being used widely with wireless devices. In this paper, we introduce the mobile M/VC application framework that supports the rapid constructions of mobile monitoring and control (M/VC) applications. The mobile M/VC application framework uses the mobile Observer/Observable pattern that extends the Java's Observer/Observable for automatic interactions of server and client objects in wireless environments. It also provides the Multiplexer and Demultiplexer classes that supports the assembly feature of Observer and Observable objects. To construct an application using the framework, developers just need to create necessary objects from the Observable and MobileObserver classes and inter-connect them structurally(like the plug-and-play style) through the Multiplexer and Demultiplexer objects. Then, the state change of Observable objects is notified to the connected Observer objects and user's input with Observer objects is propagated to Observable objects. These mechanism is the main process for monitoring and control applications. Therefore, the mobile M/VC application framework can improve the productivity of mobile applications and enhance the reusability of such components as Observer and Observable objects in wireless environments.