• The Korean Publising Journal, Monthly
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• s.286
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• pp.22-22
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• 2000

• Applied Chemistry for Engineering
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• v.28 no.4
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• pp.479-484
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• 2017

In this study, antioxidative activities and cellular protective effects of 70% ethanol extracts and fractions from lavender were evaluated. The scavenging activity ($FSC_{50}$) of free radical (1,1-phenyl-2-picrylhydrazyl, DPPH) was 46.6, 45.5 and $477.5{\mu}g/mL$ in the 70% ethanol extract, ethyl acetate fraction and aglycone fraction, respectively. The reactive oxygen species scavenging activities (${OSC_{50}$) of 70% ethanol extract, ethyl acetate fraction and aglycone fraction were 8.1, 3.3 and $17.6{\mu}g/mL$, respectively, and they showed lower antioxidative activity than that of using L-ascorbic acid ($1.5{\mu}g/mL$). However, the aglycone fraction showed higher photohemolysis protective effect than that of using the 70% ethanol extract and ethyl acetate fraction. At $50{\mu}M$ concentration, the cellular protective effect (${\tau}_{50}$) of 70% ethanol extract, ethyl acetate fraction and aglycone fraction from lavender was 70.6, 87.2 and 165.2 min, respectively. In particular, the lavender aglycone fraction showed 3.8 times higher cellular protective effect than that of (+)-${\alpha}$-tocopherol. The lavender fractional components including luteolin 7-O-glucuronide, vitextin, rosmarinic acid, luteolin, and apigenin were identified using TLC and LC-MS. However, the lavender aglycone fraction did not show any significant increase in flavonoids (luteolin and apigenin) compared to that of the ethyl acetate fraction. In conclusion, it is suggested that lavender may be applied as an antioxidant material in cosmetic industries.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.35 no.2
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• pp.125-134
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• 2009

In this study, the antioxidative effects, inhibitory effects on tyrosinase, and component of non-fermented and fermented Lavandula angustifolia extracts were investigated. The ethyl acetate fraction of fermented extract (5.95 ${\mu}g/mL$) showed the most prominent the free radical (1,1-diphenyl-2-picrylhydrazyl, DPPH) scavenging activity ($FSC_{50}$). Reactive oxygen species (ROS) scavenging activities ($OSC_{50}$) of L. angustifolia extracts on ROS generated in $Fe^{3+}-EDTA/H_2O_2$ system were investigated using the luminol-dependent chemiluminescence assay. The ethyl acetate fraction of fermented extract (1.45 ${\mu}g/mL$) showed the most prominent ROS scavenging activity. The protective effects of extract/fractions of L. angustifolia on the rose-bengal sensitized photohemolysis of human erythrocytes were investigated. The L. angustifolia extracts suppressed photohemolysis in a concentration dependent manner (1 ${\sim}$ 50 ${\mu}g/mL$). The inhibitory effect of L. angustifolia extracts on tyrosinase was investigated to assess their whitening efficacy. Inhibitory effects ($IC_{50}$) on tyrosinase were determined with ethyl acetate fraction of L. angustifolia extract (144.80 ${\mu}g/mL$) and ethyl acetate fraction of fermented extract (122.40 ${\mu}g/mL$). Fractions of ethyl acetate and fermented extracts showed both 3 band in TLC and 3 peaks, 2 peaks in HPLC (340 nm), respectively. In each chromatography, fractions of ethyl acetate both from non-fermented and fermented L. angusfifolia have rosmarinic acid in common. These results indicate that the component and content of non-fermented and fermented extracts of L. angustifolia are different. Both of the extract of L. angustifolia can be used as an antioxidant.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 1999.11a
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• pp.407-412
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• 1999

본 연구에서는 향이 자율신경계에 미치는 영향을 알아보고자 100%의 Rose oil bulgarian, Lemon oil misitano, Jasmin abs., Lavender oil france (KIMEX co. Ltd)의 네가지 향을 사용하여 심전도, 피부온도, 피부저항의 생리신호를 측정하였고, 생리신호의 측정과 함께 주관적 설문지의 평가를 통해 생리신호와의 상관성을 살펴보았다. 주관적 평가 중 양극 척도의 긴장/이완에 해당되는 문항의 분석결과 장미>자스민>레몬>라벤더 순으로 피험자들에 의해 장미가 가장 긴장된다는 결과를 나타냈다. 향의 선호도 조사에서는 장미향이 가장 진한 향으로 레몬 향이 가장 좋은 향으로 분석결과가 나왔다. 생리신호 중 평균 R-R 간격의 측정 결과는 장미향에서 가장 긴장도가 높게 나타났으며 이에 따른 주관적 평가 결과 역시 장미향이 긴장도가 높게 나와 생리신호와 주관적 평가의 결과가 상관성을 가지고 있음을 알 수 있었고, 피부온도 결과에서는 평균 R-R 간격에서 긴장도가 가장 높은 장미가 피부온도가 가장 높게 나왔다. 피부저항은 레몬 향이 가장 긴장된 것으로 나온 반면 라벤더가 가장 이완으로 나타났으며 라벤더의 경우 주관적 평가와의 상관성을 가짐을 알 수 있었다. 이와 같이 향이 자율신경계에 미치는 영향을 알아보고자 주관적 평가와 생리신호를 동시에 측정하였는데 그 결과 주관적 평가와 생리신호의 상관성을 통해 향이 자율신경계에 어떤 영향을 미치는가를 알 수가 있었다.

• 한국보건간호학회:학술대회논문집
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• 2006.06b
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• pp.179-180
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• 2006

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 2009.05a
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• pp.201-204
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• 2009

미용 향장분야에서 많이 사용되고 있고, 소염작용, 진통효과, 면역증진작용, 강장작용이 있다고 알려진 저먼 카모마일, 라벤더, 샌달우드, 호호바 등의 혼합 아로마 오일을 NC/Nga 생쥐의 피부에 도포하여 생쥐의 피부조직내 염증세포와 mast cell 의 변화를 파악하여 아토피 피부염에 대한 효과를 검증하였다. 그 결과 아로마 혼합오일인 CLS 가 아토피 피부염의 주증상인 표피세포의 각질화와 mast cell의 감소에 영향을 주어 아토피 피부염에 효과가 있을 것으로 사료된다.

• Journal of Korean Public Health Nursing
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• v.20 no.2
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• pp.174-182
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• 2006

Purpose: The purpose of this study was to test the effect of lavender fragrance on speech anxiety and public speech behavior of nursing students. Method: The subjects were 89 students in the nursing department of "K" college. We administered vaporizers containing lavender to the experimental group to measure the degree of speech anxiety and public speech behavior at pre-treatment and post-treatment. Results: The difference of variance in speech anxiety between the experimental and control groups was not significant (p=.477). However, the speech anxiety of the experimental group from pretest to post-test was significantly increased (p=.061). In addition, public speech behavior in the experimental group showed greater improvement than that in the control group (p=.000). Conclusion: This study has provided preliminary evidence that lavender fragrance may improve public speech behavior.

• Journal of Korean Public Health Nursing
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• v.20 no.1
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• pp.87-94
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• 2006

Purpose: To explore the effect of lavender fragrance on depression and anxiety of nursing students intending to take the national licensing examination. Methods: Twenty-four nursing students were studied for one week during which they underwent lavender fragrance treatment using a necklace. All subjects were in the department of nursing in 'K' college. Before and after treatment, the severity of depression and anxiety was evaluated by questionnaire. Results: After treatment, the severity of depression had not decreased significantly (p=.139) but the severity of anxiety had (p=.030). Conclusion: According to the study results, it can be concluded that lavender fragrance showed an effect on anxiety among nursing students intending to take the national licensing examination and choose a job.

• Proceedings of the Korean Society of Postharvest Science and Technology of Agricultural Products Conference
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• 2002.08a
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• pp.137.1-137
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• 2002

• Journal of the Korean Society of Food Science and Nutrition
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• v.34 no.8
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• pp.1130-1135
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• 2005

The objective of this study was to evaluate the antimicrobial activity of four herb extracts from lavender, patchouli, rosemary and eucalyptus possibly used as food preservatives. Minimum inhibitory concentration of France rosemary extracts was 29.1 mg/mL against C. albicans ATCC 10231 and 14.5 mg/mL against B. subtilis ATCC 6613 and E. coli ATCC 25922. Both of France rosemary and American lavender herbal extracts were thermally stable between 40$^{\circ}C$ and 121$^{\circ}C$ and were stable at only neutral pH. Microbial growth was repressed by adding 2.9 mg of a commercial herbal extracts in 20 mL liquid medium with France rosemary extracts and American lavender extracts.