• Title/Summary/Keyword: 동일 질환

Search Result 316, Processing Time 0.023 seconds

Mathematical Programming and Optimization of the Resource Allocation and Deployment for Disaster Response : AED case study (수리계획법을 활용한 방재자원 배치 최적화: AED 배치 사례)

  • Hwang, Seongeun;Lee, Nagyeong;Jang, Dongkuk;Shin, Dongil
    • Journal of the Korean Institute of Gas
    • /
    • v.25 no.3
    • /
    • pp.53-58
    • /
    • 2021
  • The number of patients with cardiovascular diseases who experience an out-of-hospital cardiac arrest (OHCA) are increasing among young adults as well as the aged population. An automated external defibrillator (AED) is vital in improving survival rates of OHCA victims. Survival rates of OHCA were shown to decline exponentially in time to defibrillation, yet studies in Korea are uncommon that captures the properties of their survival rates in examining optimal locations of AEDs. In this study, we worked on the maximal gradual coverage location problem (MGCLP) with exponential decay coverage function to decide on their optimal locations. The exponential decay coverage function mitigates the drawback of over-estimating survival rates of OHCA patients. It is expected that a more sophisticated facility location problem will be developed to identify the "emergent" characteristics of pedestrians who responds to the OHCA occurrence by incorporating random pedestrian locations and movement through simulation.

Anti-inflammatory effect of Porphyra yezoensis ethanol extract through the inhibited NF-κB and JNK activation in LPS-PG stimulated HGF-1 cells (사람 치은섬유모세포에서 NF-κB와 JNK 활성 억제를 통한 돌김 에탄올 추출물의 항염증 효과)

  • Park, Chung-Mu;Yoon, Hyun-Seo
    • Journal of the Korea Convergence Society
    • /
    • v.9 no.12
    • /
    • pp.81-88
    • /
    • 2018
  • Human gingival fibroblast (HGF) is the main cell type existed in periodontium and produces a variety of inflammatory mediators by external stimuli. In this study, the anti-inflammatory activity of Porphyra yezoensis ethanol extract (PYEE) on LPS-PG lipopolysaccharide from Porphyromonas gingivalis activated HGF-1 cell. Up-regulated iNOS and COX-2 expressions by LPS-PG were significantly attenuated by PYEE treatment in a dose-dependent manner. In addition, activated nuclear factor $(NF)-{\kappa}B$ was also dose-dependently inhibited by PYEE treatment. Among upstream signaling molecules, PYEE treatment inhibited phosphorylation of c-Jun $NH_2$-terminal kinase (JNK) but did not give any effect on other molecules. On the other hand, one of phase II enzymes, NAD(P)H:quinone dehydrogenase (NQO)-1, was analyzed due to its anti-inflammatory activity, which was upregulated by PYEE treatment. Consequently, PYEE could be candidates for the prevention and treatment of periodontal diseases.

Effects of 12-Weeks Dance Sports Exercise on Body Composition, Irisin, Adiponectin and Blood Lipids in Obesity Elderly Women (12주간의 댄스스포츠운동이 비만노인여성의 신체조성, 아이리신, 아디포넥틴 및 혈중지질에 미치는 영향)

  • Lee, jin-wook;Zhang, seok-am;Kim, chan-yang
    • 한국체육학회지인문사회과학편
    • /
    • v.58 no.1
    • /
    • pp.271-284
    • /
    • 2019
  • The purpose of this study was to analyze effects of 12 weeks dance sports on body composition, irisin, adiponectin and blood lipids in obesity elderly women. The subjects were 26 obesity elderly women who do not have medically problems. The subjects randomly assigned to two groups; dance sports exercise(n=13), control(n=13). The subjects in dance sports group were participated for 60 minutes/day with two times/wk for 12 weeks, whereas subjects in control group were asked to maintain normal lifestyle during the same intervention period. The results of the present study showed that the blood irisin was significantly increased in the exercise group. The blood adiponectin level tended to increase in the exercise gorup. The blood lipids, TG and LCL-C were significantly decreased in the exercise group. The TC was slightly decreased, and the HDL-C was slightly increased. In conclusion, low irisin and adiponectin level in obese people have a positive effect on obese elderly women after dance sports. Therefore, exercise is thought to be good for the care of elderly obesity.

The changes of health-related fitness for the elderly women depend on the types of exercise (운동 형태에 따른 노인 여성들의 건강관련 체력의 변화)

  • Yoon, Byung-Kon;Park, Chan-Ho
    • Journal of the Korean Applied Science and Technology
    • /
    • v.37 no.6
    • /
    • pp.1728-1737
    • /
    • 2020
  • The purpose of this study was to verify the effects of the types of exercise on the health-related fitness among the elderly women, and to provide the information for managing and preventing the chronic disease. 40 elderly women who living in the B metropolitan city participated in the study and randomly divided four groups(control, aerobic exercise, resistance exercise, and combined exercise). The exercise groups performed 50 min, 3 times/week for 8 weeks at RPE 11-13. Low body strength, dynamic balance, static balance, and agility were significantly improved in all exercise groups after the intervention. Cardiovascular endurance was improved in aerobic and combined exercise groups. Consequently, any types of exercise could be improved the daily living fitness for elderly women if exercise intensity were the same. In addition, the combined exercise may be more suitable type of exercise for elderly.

Individual Variations in the Code of the International Classification of Disease for Similar Outpatient Conditions among General Practitioners (동일 질환에 대한 상병분류기호의 의료기관별 변이에 관한 연구)

  • 문옥륜;김창엽;김명기
    • Health Policy and Management
    • /
    • v.2 no.1
    • /
    • pp.66-79
    • /
    • 1992
  • The code of the International Classification of Disease(ICD) is seriously questioned on its effectiveness in identifing an independent disease entity from similar conditions at general practitioner's offices. This study has attempted to show individual coding variations in ICD for similar ambulatory care conditions. It has been assumed that a following outpatient visit is regarded as the sane kind of visit owing to the same disease if a visit to the different source of care would be mad within an interval of less than two days. The 'D' health insurance association was selected for this analysis. The 'D' association had 153,298 members and made claims of 642,605 outpatient care in 1990. Out of the total outpatient claims, 8.6%(55,102 claims) were counted as the same disease which could meet the above assumption. Percent of conditions classified as the 10 leading causes of frequent visits which were matched accurately to the subsequent ICD diagnostic code found to be 15.8% on the average. The URI was noted for the highest concurrence rate of 20.4%. This proportion was even decreased to 11.6% on the case of chronic disease. Despite the fact that the assumption underlying the definition of the above same disease is rather rough and inappropriate, this study reveals that the code of ICD currently in use has weaknesses in seperating a certain independent disease from similar conditions at the outpatient setting. Thus, efforts need to be elaborated to meet the need of a new system of classification for conditions and diseases encountering at ambulatory care.

  • PDF

The Effect of Computer Game and Stretching on Muscle Tone and Concentration (컴퓨터 게임과 스트레칭이 근 긴장도 및 집중력에 미치는 영향)

  • Ko, Min-Gyun;Song, Chang-Ho;Lee, Byung-Hoon
    • Journal of Korea Entertainment Industry Association
    • /
    • v.13 no.1
    • /
    • pp.225-233
    • /
    • 2019
  • The study was to find out the effects of computer game and stretching on muscle tone and concentration. The subjects were 30 adults, who were divided into 15 stretching group and 15 control group after applying computer game for 120 minutes. The subjects measured muscle tone and concentration before experiment, the same measurements were made before and after applying the stretching. The muscle tone was respectively measured after 60 minutes and 120 minutes of computer game. The results showed that muscle tone increased significantly after 60 minutes and 120 minutes of computer game, and significantly decreased in the stretching intervention group. Concentration increased significantly after computer game, but there was no significant difference after application of stretching. In this study, computer game increased muscle tone and concentration, and stretching decreased increased muscle tone. Therefore, proper stretching after computer games will reduce musculoskeletal diseases caused by increased muscle tone, and development of appropriate game contents will be an effective tool for concentration training.

A Study on the Priorities of Enabling Digital Healthcare Platform for Small and Medium Enterprises : A Comparative Analysis of Consumers and Suppliers

  • Yeon-Kyeong Lee;Min-Jung Lee
    • Journal of the Korea Society of Computer and Information
    • /
    • v.29 no.6
    • /
    • pp.131-141
    • /
    • 2024
  • The aging population and worsening lifestyle habits have increased the risk of chronic diseases. This has heightened the importance of preventive healthcare, particularly through personalized health management services based on individual health data. Despite this, the domestic digital healthcare industry remains underdeveloped. Given the need for acceptance from both consumers and providers, this study uses the Analytic Hierarchy Process (AHP) to identify success factors for health management service platforms. AHP evaluates the relative importance of various factors to aid decision-making. Results show that providers prioritize data analysis and platform design, laws and regulations, and data standardization, while consumers prioritize system stability, laws and regulations, and system security. These findings highlight the need for strategies to bridge the expectation gap to effectively promote health management service platforms.

The analysis of medical use characteristics of elderly patients and the factors influencing them depending on whether or not the manpower of long-term care hospital is secured (요양병원 인력확보 여부에 따른 고령환자의 의료이용 특성과 영향을 미치는 요인 분석)

  • Yun-Jeong Chang
    • Journal of the Health Care and Life Science
    • /
    • v.10 no.2
    • /
    • pp.265-274
    • /
    • 2022
  • In this paper, the 2018 elderly patient data sets among the patient sample data of the Health Insurance Review & Assessment Service and the 260,425 statements of patients admitted to the long-term care hospitals were together used. Accordingly, the characteristics of each hospital type were analyzed by classifying the addition type of long-term care hospitals according to whether or not to secure the required manpower and whether or no to secure more than two-thirds of required nurses. However, in evaluating whether or not to secure more than 2/3 of necessary nurses and whether or not to secure the necessary manpower, the relative value points were not considered, and the same amounts of value has been maintained for 13 years, so the relevant value needs to be revised.

Usefulness of Posture Change to Prevent Overlapping of Heart and Other Organs in Myocardial Perfusion SPECT using $^{99m}Tc$ Labeled Compound ($^{99m}Tc$ 표지화합물을 사용한 심근 관류 SPECT 검사에서 심장과 타 장기와의 중첩 방지를 위한 자세 변화의 유용성)

  • Lee, Dong-Hyuk;Oh, Shin-Hyun;Jeong, Seok;Jo, Seok-Won;NamKoong, Hyuk;Kim, Jae-Sam;Lee, Chang-Ho
    • The Korean Journal of Nuclear Medicine Technology
    • /
    • v.16 no.1
    • /
    • pp.62-69
    • /
    • 2012
  • Purpose: The present study has an objective of effectively separating and making observations on a portion of radiopharmaceutical excreted via digestive organ to remain in the organ and invade a heart shadow. Materials and methods: When heart shadow is blocked by the organ in tests during a resting phase and a loaded phase, additional images were obtained using immobilization device. The immobilization devices were used to tilt the upper body forward from supine position. Results: In the reconstructed image for the separated case, as compared with the case where a part of organ is overlapped with heart, in terms of an overall mean value for each parameter, the end-diastolic volume increased by 2.75 mL, the end-systolic volume decreased by 3.16 mL, the left ventricle cardiac coefficient increased by 3.58%, and the area of defect region decreased by 3.58 and 3.92 cm for loading and resting phase, respectively. Conclusions: In the present study with myocardial perfusion SPECT, overlapped areas of heart and other organs could be effectively separated and visualization by the use of an immobilization device.

  • PDF

Polymorphisms of the NR3C1 gene in Korean children with nephrotic syndrome (한국 신증후군 환아에서 NR3C1 유전자 다형성 분석)

  • Cho, Hee Yeon;Choi, Hyun Jin;Lee, So Hee;Lee, Hyun Kyung;Kang, Hee Kyung;Ha, Il Soo;Choi, Yong;Cheong, Hae Il
    • Clinical and Experimental Pediatrics
    • /
    • v.52 no.11
    • /
    • pp.1260-1266
    • /
    • 2009
  • Purpose : Idiopathic nephrotic syndrome (NS) can be clinically classified as steroid-sensitive and steroid-resistant. The detailed mechanism of glucocorticoid action in NS is currently unknown. Methods : In this study, we investigated 3 known single nucleotide polymorphisms (SNPs) (ER22/23EK, N363S, and BclI) of the glucocorticoid receptor gene (the NR3C1 gene) in 190 children with NS using polymerase chain reaction-restriction fragment length polymorphism and analyzed the correlation between the genotypes and clinicopathologic features of the patients. Results : Eighty patients (42.1%) were initial steroid nonresponders, of which 31 (16.3% of the total) developed end-stage renal disease during follow-up. Renal biopsy findings of 133 patients were available, of which 36 (31.9%) showed minimal changes in NS and 77 (68.1%) had focal segmental glomerulosclerosis. The distribution of the BclI genotypes was comparable between the patient and control groups, and the G allele frequencies in both the groups were almost the same. The ER22/23EK and N363S genotypes were homogenous as ER/ER and NN, respectively, in all the patients and in 100 control subjects. The BclI genotype showed no correlation with the NS onset age, initial steroid responsiveness, renal pathologic findings, or progression to end-stage renal disease. Conclusion : These data suggested that the ER22/23EK, N363S, and BclI SNPs in the NR3C1 gene do not affect the development of NS, initial steroid responsiveness, renal pathologic lesion, and progression to end-stage renal disease in Korean children with NS.