• Proceedings of the Korea Information Processing Society Conference
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• 2011.11a
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• pp.1067-1070
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• 2011

현재 뇌에 대한 연구는 지속적으로 연구되고 있는 분야 중에 하나이다. 뇌파나 뇌의 활동들을 분석할 수 있는 장비들이 개발되면서 더욱 활발하게 연구되어지고 있다. 기중 뇌의 기능에 대한 연구들도 화발하게 연구되고 있는 분야 중에 하나이다. 뇌의 기능은 보고, 듣고, 말하고, 생각하는 등의 모든 행위들과 연관되어있다. 또한 그러한 기능들은 인지능력이라고 하기도 한다. 인지능력은 인지적, 정신적인 요구가 필요하다. 이러한 것을 인지부하라고 하고, 과도한 인지적, 정신적인 요구는 인지과부하라고 한다. 인지부하에 따라서 인지능력은 영향을 받는다고 할 수 있다. 본 연구에서는 인지부하에 따라서 인지능력이 변화하는 정도를 실험하였다.

• Journal of Biomedical Engineering Research
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• v.22 no.5
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• pp.377-384
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• 2001

Generally. there have been limitations to investigate structural brain abnormalities with MR images for psychiatric patients. such as schizophrenia. depression and autism, since the brain abnormalities of psychiatric Patients are too small to be detected easily. It has been suggested to exploit the result of size-comparison or analysis of specified Part in various brain tissues. Results of brain analysis highly depend on accuracy of the brain segmentation because it is hard to segment image that the boundary between tissues in the brain MRI is inherently value. In this Paper. we improve the quality of brain segmentation so that we increase the credit of brain analysis. In addition, we Provide the improved images for studying brain abnormalities through left-right insular volume measure using handy software tool .

• Clinical and Experimental Pediatrics
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• v.52 no.12
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• pp.1337-1347
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• 2009

Purpose:Taurine (2-aminoethanesulfonic acid) is a simple sulfur-containing amino acid. It is abundantly present in tissues such as brain, retina, heart, and skeletal muscles. Current studies have demonstrated the neuroprotective effects of taurine, but limited data are available for such effects during neonatal period. The aim of this study was to determine whether taurine could reduce hypoxic-ischemic (HI) cerebral injury via anti-apoptosis mechanism. Methods:Embryonic cortical neurons isolated from Sprague-Dawley (SD) rats at 18 days gestation were cultured in vitro. The cells were divided into hypoxia group, taurine-treated group before hypoxic insult, and taurine-treated group after HI insult. In the in vivo model, left carotid artery ligation was performed in 7-day-old SD rat pups. The pups were exposed to hypoxia, administered an injection of 30 mg/kg of taurine, and killed at 1 day, 3 days, 1 week, 2 weeks, and 4 weeks after the hypoxic insult. We compared the expressions of Bcl-2, Bax, and caspase-3 among the 3 groups by using real- time polymerase chain reaction (PCR) and western blotting. Results:The cells in the taurine-treated group before hypoxic insult, although similar in appearance to those in the normoxia group, were lesser in number. In the taurine-treated group, Bcl-2 expression increased, whereas Bax and caspase-3 expressions reduced. Conclusion:Taurine exerts neuroprotective effects onperinatal HI brain injury due to its anti-apoptotic effect. The neuroprotective effect was maximal at 1-2 weeks after the hypoxic injury.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.10 no.7
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• pp.1673-1679
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• 2009

This study was to examine the effectiveness of prefrontal Neurofeedback training by observing the pre and post brainwave measurement results of about Y kindergarten kids 50 (experimental group 25.comparative group 25) subjects who have shown corelation, in between the months of Mar. 2008 and Nov. 2008. As the brainwaves are adjusted by timeseries linear analysis, the result confirmed the differences of both corelation. The result of the study suggest Neurofeedback technique's possibility in positively affecting the subjects' corelation and mental state.

• Therapeutic Science for Rehabilitation
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• v.7 no.1
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• pp.11-26
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• 2018

Objective : This case study was to verify effects of cognitive rehabilitation and swallowing rehabilitation on Hypoxic-Ischemic Brain Injury patient by Suicidal Attempt. Methods : The subject was a 32-year old Hypoxic-ischemic brain injury patient by suicidal attempt. He received treatment once a day five times a week, for a half an hour for each session from September 8th to December 16th, 2016. Treatment were cognitive and swallowing rehabilitation. He was assessed based on Mini-Mental State Examination-Korean (MMSE-K), Korean-Modified Barthel Index (K-MBI), Computerized Neurocognitive Function Test (CNT), Videofluoroscopic Dysphagia Scale (VDS), American Speech-Language-Hearing Association National Outcomes Measurements System (ASHA-NOMS). Results : The patient's total MMSE-K score increased from 25 to 27. His K-MBI score increased from 74 to 88. His memory, attention span, and executive function (DST, VST, SWCT, WCST) by CNT scores were improved. VDS score has no changes to 34, 44.5 and 34. ASHA-NOMS score also has no change to 6, 2 and 6. Conclusion : The study showed that the application of the treatment of cognitive and swallowing in hypoxic-ischemic brain injury patient by suicidal attempt results has positive effects on cognitive functions, and swallowing function.

• 대한공업교육학회지
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• v.33 no.1
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• pp.23-43
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• 2008

The purpose of this study is to provide some necessary baseline data to the information prodigy related research through the study on the brain left/right tendency of information prodigies. Subjects were 298 gifted students(59 information, 79 mathematics, 80 science, 40 invention, 40 social science) and 114 general students summing up 412 in the schools of Daejeon metropolitan area. 'Brain Tendency Test' developed by Torrance and modified by Ko in Korean was used as a tool to measure the prodigies' brain tendencies. Data analysis has been done with the $x^2$ test of frequency with the alpha = .05. The results of this study are as follows. 1) The information gifted students have tendencies of utilizing right brain hemisphere at the most, both left/right brain(whole brain) utilization at the second, and left brain utilization at the last. 2) There was statistically no difference between information prodigies and general students in the left/right brain tendency. 3) There was statistically mild evidence to support the notion that there are some differences in the brain tendency between the group of information prodigies and the group of other area of the prodigies. The degree of inclination to utilize the whole brain hemisphere for the prodigies of the other area was the highest compare to other left/right brain utilization while the information prodigies tend to utilize the right brain hemisphere at the most. 4) The female information prodigies have tendencies of utilizing while brain area at the most, right brain utilization at the second, and left brain utilization at the last contrary to the brain utilization tendencies in the male information prodigies which are the same as the brain utilization tendencies of the information prodigies. However there was no difference in brain tendencies statistically between the two groups since the female subjects were too small.

• Proceedings of the Korean Society of Computer Information Conference
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• 2016.07a
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• pp.295-296
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• 2016

본 연구에서는 LED 광 자극이 뇌의 어느 영역을 자극하여 신경신호를 전달하는지에 관해서 관찰하고자 연구를 진행하였다. 광 자극에 의한 뇌 영역의 활성변화를 관찰하기 위하여 실험용 소동물과 영상장비인 9.4T MRI를 이용하여 연구를 수행 하였다. 실험용 소동물은 Balb/c 마우스를 이용하였으며 기능적 자기공명영상 획득 방법 중 하나인 에코평면영상 기법을 이용하여 뇌 영상을 획득 하였다. 획득한 영상을 바탕으로 뇌 영역의 자극 정도를 확인해보기 위해 영상처리기법인 재편성(realignment), 일치(co-registration), 표준화(normalization), 평활화(smoothing) 방법으로 영상을 전처리 하고, statistical parametric map (SPM12)을 사용하여 분석하였다. 본 연구에서는 광자극이 소동물 뇌 영역 중 하나인 상구(Superior colliculus)영역과 대뇌의 시각피질 (visual cortex, V1) 영역에서 자극을 일으키는 것을 확인할 수 있었다.

• The Journal of the Korea Contents Association
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• v.10 no.1
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• pp.305-316
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• 2010

The purpose of this study was to identify the relationships between preschool teachers' hemispheric mode indicator and creative personality. The subjects were 205 preschool teachers from kindergarten or nursery school in Busan. The McCanthy(1993)'s HMI(Hemispheric Mode Indicator) and Torrance(1988)'s WKOPAY(What Kind Of Person Are You?) were used to examine the relationships preschool teachers' hemispheric mode indicator and creative personality. Results of this study as follows ; first, the hemispheric mode indicator of right hemispheric dominance were significantly positively correlated to the creative personality and inquisitiveness but negatively correlated to self-confidence among elements of creative personality. Second, the creative personality was significant difference according to hemispheric dominance types. That is, the creative personality of right hemispheric dominance was significantly higher than that of left or exhibit balanced hemispheric dominance but it was no difference between left hemispheric dominance and exhibit balanced hemispheric dominance. Third, there were significant difference self-confidence, inquisitiveness, and awareness of others but no difference Acceptance of Authority and Disciplined Imagination among elements of creative personality according to hemispheric dominance types.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.25 no.7A
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• pp.1006-1016
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• 2000

This study is to segment white matter, gray matter, and cerebrospinal fluid(CSF) on a brain MR image and to calculate the volume of each. First, after removing the background on a brain MR image, we segmented the whole region of a brain from a skull and a fat layer. Then, we calculated the partial volume of each component, which was present in scanning finite thickness, with the arithmetical analysis of gray value from the internal region of a brain showing the blurring effects on the basis of the MR image forming principle. Calculated partial volumes of white matter, gray matter and CSF were used to determine the threshold for the segmentation of each component on a brain MR image showing the blurring effects. Finally, the volumes of segmented white matter, gray matter, and CSF were calculated. The result of this study can be used as the objective diagnostic method to determine the degree of brain atrophy of patients who have neurodegenerative diseases such as Alzheimer's disease and cerebral palsy.

• Korean Journal of Cognitive Science
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• v.21 no.2
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• pp.309-338
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• 2010

In this paper, we studied the brain-computer interface (BCI). BCIs help severely disabled people to control external devices by analyzing their brain signals evoked from motor imageries. The findings in the field of neurophysiology revealed that the power of $\beta$(14-26 Hz) and $\mu$(8-12 Hz) rhythms decreases or increases in synchrony of the underlying neuronal populations in the sensorymotor cortex when people imagine the movement of their body parts. These are called Event-Related Desynchronization / Synchronization (ERD/ERS), respectively. We implemented a BCI-based mouse interface system which enabled subjects to control a computer mouse cursor into four different directions (e.g., up, down, left, and right) by analyzing brain signal patterns online. Tongue, foot, left-hand, and right-hand motor imageries were utilized to stimulate a human brain. We used a non-invasive EEG which records brain's spontaneous electrical activity over a short period of time by placing electrodes on the scalp. Because of the nature of the EEG signals, i.e., low amplitude and vulnerability to artifacts and noise, it is hard to analyze and classify brain signals measured by EEG directly. In order to overcome these obstacles, we applied statistical machine-learning techniques. We could achieve high performance in the classification of four motor imageries by employing Common Spatial Pattern (CSP) and Linear Discriminant Analysis (LDA) which transformed input EEG signals into a new coordinate system making the variances among different motor imagery signals maximized for easy classification. From the inspection of the topographies of the results, we could also confirm ERD/ERS appeared at different brain areas for different motor imageries showing the correspondence with the anatomical and neurophysiological knowledge.