• 제목/요약/키워드: 남동석

검색결과 189건 처리시간 0.027초

하악두연골의 성장에 관한 시험관적 연구 (GROWTH OF MANDIBULAR CONDYLAR CARTILAGE OF THE RAT IN VITRO)

  • 이동열;남동석
    • 대한치과교정학회지
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    • 제22권2호
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    • pp.309-325
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    • 1992
  • The purpose of this study was to evaluate the effect of intrinsic factor and extrinsic factor for growth of the mandibular condylar cartilage of 4 day-old rats in a serum-free medium for 1, 4, 7, 14 days. They were compared with normal growth in vivo and with growth of spheno-occipital synchondrosis in serum-free medium. The cellular kinetics of cartilages were evaluated by auto-radiography of tritiated thymidine. 1. Condylar cartilage was enlarged with rounded head on day 14 of experiment while in vivo the rounded-headed shape changed into functionally flattened appearance. 2. On day 14 of experiment, a severe reduction of the proliferative zone and a considerable increase of the hypertrophic zone were observed while in normal control group endochondrol bone formation and bone marrow were observed. 3. The proliferative activity in the proliferative zone of condylar cartilage detected by $^3H-thymidine$ incorporation was lower than that of normal control group and decreased more than that of spheno-occipital synchondrosis, but it continued during the 14 days of culture. 4. The continued maintenance of condylar cartilage and morphologic change were disturbed in this culture system, but cell division within the proliferative zone was continued and probably linked to intrinsic factor.

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Cyclosporin A에 의한 치은 증식증에서 FGF-5와 FGF-7의 발현 양상에 대한 연구 (THE EXPRESSION OF FGF-5 AND FGF-7 IN THE CYCLOSPORIN A-INDUCED GINGIVAL HYPERPLASIA)

  • 정미향;김성곤;윤경인;남동석
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • 제32권3호
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    • pp.216-221
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    • 2006
  • Cyclosporin A-induced gingival hyperplasia is frequently found in the patients who have been received an immunosuppressant for the organ transplantation. However, its exact mechanism is still unknown. The expression of FGF-5 and FGF-7 were studied in cyclosporine A-induced gingival hyperplasia (CGH) and inflammatory gingival hyperplasia (IGH). Immunohistochemistry and in situ hybridization were used for localization of protein and mRNA. The expression of FGF-5 and FGF-7 was different from CGH and IGH. FGF-5 and FGF-7 was strongly expressed in fibroblast in CGH (P<0.005 and P<0.05, respectively). FGF-5 mRNA was localized in the middle portion of connective tissue. FGF-7 mRNA was also identified in fibroblasts and mast cells. In conclusion, FGF-5 and FGF-7 were produced excessively by fibroblasts in CGH. Considering their known functions, their expression in CGH is important for production of collagen and proliferation of fibroblasts.

제1소구치 발거가 II급 1류 부정교합자의 안모와 치열궁에 미치는 영향에 관한 연구 (A STUDY ON THE EFFECTS OF THE 1st BICUSPID EXTRACTION ON THE CHANGES IN FACE AND DENIAL ARCH FORM IN ANGLE CLASS II DIV. 1 MALOCCLUSIONS)

  • 최낙준;남동석
    • 대한치과교정학회지
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    • 제16권1호
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    • pp.167-177
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    • 1986
  • This study was undertaken to compare the main differences and its effects of the 4 first bicuspid extraction on the face and dental arch of the class II div 1 malocclusion. The subjects consisted of twenty two class II div 1 malocclusion, four males, eighteen females, were 14 Years 2 Months old at the stan of the treatment 16 Year 3 Months old at the end of the treatment. (mean age) Twenty one variables were observed by comparing the statistical data of the pretreatment records with postteratment records, which were consited of eight varibles on the study model digitation, thirteen variables on the tracing of the lateral cephalogram. The following results were obtained. 1. No significant change was observed in the intercanine width. 2. Intercuspal widths of the 1st. premolar and 2nd. premolar were decreased. 3. Change of the overjet was dependant upon upper anterior rather than lower anterior. 4. No significant changes were observed in facial plane angle and ANB angle. 5. Uprighting of the lower 1st. molar had an effect on the increase of the facial height.

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Multiloop Edgewise Arch Wire의 역학적 해석 (MECHANICAL ANALYSIS ON THE MULTILOOP EDGEWISE ARCH WIRE)

  • 전경민;남동석
    • 대한치과교정학회지
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    • 제21권1호
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    • pp.31-51
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    • 1991
  • This study was designed to survey the stress distributions and deflections which were derived from MEAW by the computer-aided three dimensional finite element analysis of teeth and surrounding bone composed of 2839 solid elements and 4621 nodes. MEAW model was also made using the 90 beam elements and the results were expressed by quantitative and visible ways. The findings of this study were as follows. 1 In case of vertical load on the MEAW there were extrusions of anterior teeth and upright effects of the posterior teeth. 2. Without applying the vertical elastics on the MEAW there were intrusions of anterior teeth, but relatively mild force was transmitted to the posterior teeth area. Torque forces were observed on the incisors and molars, and canine was intruded without torque. 3. The magnitudes of forces were different by the amounts of tip back bends of MEAW. 4. The displacements were in inverse proportion to the cross section areas of the wires according to the experiment using the 5 different size arch wires. 5. The difference of deflections between the MEAW and plain arch wire was not so big as the theoretical one but the deflections of MEAW were much more than the plain arch wire in every X, Y, Z direction.

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전단력이 연골세포에 미치는 영향에 관한 연구 (THE SHEAR STRESS PROTEOME OF CHONDROCYTES)

  • 김신엽;김성곤;최제용;남동석
    • Maxillofacial Plastic and Reconstructive Surgery
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    • 제27권1호
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    • pp.9-15
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    • 2005
  • The objective of this study is screening the shear stress related proteins in chondrocytes using twodimensional electrophresis and MALDI-TOF. C-28/I2 cell line were grown. The fluid-induced shear stress(FISS) was applied using a cone viscometer at a rotational velocity of 80rpm for periods of 12 hours. Control cultures were tested under identical conditions without mechanical load application. Collected samples were used for the two-dimensional electrophoresis and MALDI-TOF. The identified proteins were calcyclin, RPE-spondin, interleukin-2, extracellular signal regulated kinase (ERK), lamin B2, porA protein, and RET-ELE1 protein. All of them showed a decreased expression. In conclusion, seven proteins were identified as a shear stress related proteins in chondrocytes. As the destruction of articular cartilage is one of main pathogenesis of TMJ internal derangement, this study will give useful information for the understanding of the molecular aspect of TMJ disease.

악안면 형태에 관한 두부방사선계측학적 연구 (A ROENTGENOCEPHALOMETRIC STUDY ON MAXILLOFACIAL MORPHOLOGY)

  • 김현순;남동석
    • 대한치과교정학회지
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    • 제13권1호
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    • pp.45-62
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    • 1983
  • To recognize the problems in malocclusion by roentgenocephalograms, the author designed a new pentagonal frame based on maxillary and mandibular bones. The subjects consisted of 44 normal occlusions (20 male and 24 female), 44 Class II division 1 malocclusions (15 male and 29 female) and 67 Class III malocclusions (31 male and 36 female). The results are as follows; 1. In normal group, the maxillary and mandibular skeletons of female we placed more closely to FH plane, so more anteriorly and upward than those of male. 2. In normal group, the posterior vertical height is longer in male than in female and the upper anterior teeth of female are in more labioversion than those of male. 3. By the X, Y coordinate values in pentagonal frame, it is helpful to recognize certain problems in malocclusions. 4. The posterior vertical height is a good indicator in detecting Angle's Class III malocclusion. 5. The maxillary and mandibular body length, the anterior point of maxillary and mandibular body length and the axial inclination of upper and lower anterior teeth can be useful in discerning Angle's Class II & Class III malocclusion.

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과개교합자의 악안면 형태에 관한 두부 X-선사진 계측학적 연구 (ROENTGENOCEPHALOMETRIC STUDY ON CRANIOFACIAL MORPHOLOGY OF DEEPBITES)

  • 김희정;남동석
    • 대한치과교정학회지
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    • 제23권3호
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    • pp.341-358
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    • 1993
  • This study was investigated to evaluate the morphologic characteristics of deepbite tendency as multiple factors. The subjects consisted of 60 control subjects(male 25, female 35) and 137 deephite patients(68 male, 69 female). The deepbite group was composed of 4 subgroups(Class I 44, Class II div. 1 40, Class II div. 2 13, Class III 40). The mean age was 21.57 year for the control group 21 year for deepbite group lateral cephalograph in centric occlusion were taken, traced, and digitized for each subject. The statistically computerized analysis was carried out with SAS program. The results were as follows ; 1. In deepbite group, saddle angle is lesser than that of normal group. 2. The vertical dysplasia is prominent on anterior lower face and is closely related with mandibular form and inclination. 3. Without consideration of sagittal relationship, the dental factors such as curve of Spee, interincisal angle, U1 to upper lip length were prominent in the deepbite group. 4. Although there were individual variances in the perioral soft tissue profile, the lip presented more protruded pattern. 5. There was no significant difference in hyoid bone position and inclination between normal and deepbite group. 6. The multivariate discriminant analysis between normal and Class I deepbite group showed that curve of Spee, AB-MP angle, interincisal angle, articular agnle were critical in the determination of deepbite as multiple factors.

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흰쥐의 실험적 치아이동시 치수의 반응에 관한 조직학적 연구 (A HISTOLOGIC STUDY ON THE RESPONSES OF PULP IN EXPERIMENTAL TOOTH MOVEMENT OF WHITE RATS)

  • 남동석
    • 대한치과교정학회지
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    • 제1권1호
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    • pp.15-20
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    • 1970
  • 저자는 흰쥐 27수의 하악제일대구치를 교정용 고무선으로 이동시킨후, 이동의 초기에 나타나는 치수의 반응을 조직학적 방법으로 관찰하는 것을 연구목적으로 하였다. 30 Gm부터 120 Gm까지의 힘을, 12수는 3일간, 15수는 7일간, 각 실험치아에 부여하였다. 관찰결과는 다음과 같았다. 1. 치수조직의 주변화는 치수혈관의 순환장애와 조상아세포의 공포형상으로 나타났다. 2. 적용시킨 힘의 증가에 따라서 상기 조직변화의 범위가 확대되었다. 3. 기외에 치근의 상아질과 백악질의 부분적 흡수도 볼 수 있었다.

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사춘기전(思春期前) 아동(兒童)의 정상(正常) 비강(鼻腔) 통기도(通氣度)에 관한 연구(硏究) (A STUDY ON NORMAL NASAL RESPIRATORY RESISTANCE IN THE PREPUBERTAL CHILDREN)

  • 양원식;서정훈;남동석;장영일
    • 대한치과교정학회지
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    • 제22권1호
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    • pp.31-42
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    • 1992
  • This study was designed to analyze normal nasal respiratory resistance in prepubertal children. The subjects consisted of 30 prepubertal children (male: 15, female: 15). The mean age was 11.4 years in male children and 11.5 years in female children. The results were as follows: I. The normal nasal respiratory patency was lower than the normal values from RION corp. 2. The normal nasal respiratory airflow rates showed no sexual differences. And there were no differences between inspiration and expiration. 3. Before and after use of nasal decongestants, there were no significant differences of normal nasal respiratory airflow rates and after the administration of nasal decongestants, nasal respiratory patency manifested lower variability. 4. The normal nasal respiratory resistance without nasal decongestants at 150 Pascal in inspiration was $0.30Pa/cm^3/sec({\pm}0.07)$ and peak nasal inspiratory airflow rate was $1016.83cm^3/sec({\pm}223.89)$. 5. The normal nasal respiratory resistance with nasal decongestant at 150 Pascal in inspiration was $0.25Pa/cm^3/sec({\pm}0.05)$ and peak nasal inspiratory airflow rate was $1148.33cm^3/sec({\pm}234.29)$.

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