• Title/Summary/Keyword: 나노바이오

Search Result 443, Processing Time 0.027 seconds

Development of Physical Cell Lysis Using a Spiked CNT Membrane for Polyhydroxybutyrate Recovery (폴리하드록시부틸레이트 회수를 위한 물리적 세포 파쇄용 돌기형 탄소나노튜브 분리막 제작)

  • Jiwon Mun;Youngbin Baek
    • Membrane Journal
    • /
    • v.33 no.6
    • /
    • pp.390-397
    • /
    • 2023
  • Conventional extraction methods for polyhydroxybutyrate (PHB), a sustainable alternative to petroleum-based plastics, cause a decrease in molecular weight and a change in properties. In this work, we developed a method to extract PHB accumulated in microorganisms by physical disruption through filtration using a spiked carbon nanotube (CNT) membrane with functionalized CNT. In addition, filtration of the PHB-containing microbial solution was performed to confirm PHB extraction, which was found to be 4% more efficient than chloroform, the most used extraction method. These results indicate that the spiked CNT membrane has potential in the bioplastics recovery process.

과학기술계 소식

  • Korean Federation of Science and Technology Societies
    • The Science & Technology
    • /
    • no.7 s.446
    • /
    • pp.111-115
    • /
    • 2006
  • PDF

Factors Changing Dynamic Research Collaboration Network in Korean Nanobiotechnology (나노바이오 분야 국내 연구자의 동적 협업 네트워크 변화 요인 분석)

  • Lee, Hye Jin;Lee, Choon Shil
    • Journal of the Korean Society for Library and Information Science
    • /
    • v.52 no.1
    • /
    • pp.231-258
    • /
    • 2018
  • This study attempted to identify dynamically changing structure and analyze factors of collaboration. In order to perform this study, 1,631 articles in SCI journals were collected, and 3,898 researchers' information were extracted. To examine the dynamics of collaboration networks, the co-authorship data collected from 2001 to 2015 were divided into three sets, and were analyzed with respect to each period. The results of this study were summed up as: 1) "Co-authorship of the last year" was entirely significant factors while research career was significant only in the period of 2 to 3. 2) It was found that "Influence of the researchers" and "Emergence of the researchers" were significant factors in the period of 2 to 3 and in the period of 1 to 2. 3) "Same institutions", "Same subject", and "Journal similarity" were significant factors in all periods.

Etching treatment of vertically aligned carbon nanotubes for the application to biosensor (바이오센서로의 응용을 위한 수직 배열된 탄소나노튜브의 식각처리)

  • Jung, Seoung-Ho;Choi, Eun-Chang;Park, Yong-Seob;Choi, Won-Seok;Hong, Byung-You
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
    • /
    • 2007.11a
    • /
    • pp.353-353
    • /
    • 2007
  • 탄소나노튜브(CNT)의 tip 부분에 존재하는 금속 촉매 입자들은 불순물로써 나노전자소자에 응용하는데 좋지 않은 영향을 미칠 수 있다. 또한, 바이오센서에서 target 바이오 물질과 반응하는 물질을 CNT에 고정시키기 위해서는 CNT-tip을 개방시키는 것이 중요하다. 본 연구에서는 성장된 CNT의 tip부분에 존재하는 금속 촉매 입자의 제거와 CNT-tip을 개방하기 위해 $HNO_3$의 농도 (20, 40, 60)와 etching 시간 (5, 10, 15, 20, 25 min)에 따라 최적의 조건을 찾는 실험을 하였다.

  • PDF

Fabrication of Label-Free Biochips Based on Localized Surface Plasmon Resonance (LSPR) and Its Application to Biosensors (국소 표면 플라즈몬 공명 (LSPR) 기반 비표지 바이오칩 제작 및 바이오센서로의 응용)

  • Kim, Do-Kyun;Park, Tae-Jung;Lee, Sang-Yup
    • KSBB Journal
    • /
    • v.24 no.1
    • /
    • pp.1-8
    • /
    • 2009
  • In the past decade, we have observed rapid advances in the development of biochips in many fields including medical and environmental monitoring. Biochip experiments involve immobilizing a ligand on a solid substrate surface, and monitoring its interaction with an analyte in a sample solution. Metal nanoparticles can display extinction bands on their surfaces. These charge density oscillations are simply known as the localized surface plasmon resonance (LSPR). The high sensitivity of LSPR has been utilized to design biochips for the label-free detection of biomolecular interactions with various ligands. LSPR-based optical biochips and biosensors are easy to fabricate, and the apparatus cost for the evaluation of optical characteristics is lower than that for the conventional surface plasmon resonance apparatus. Furthermore, the operation procedure has become more convenient as it does not require labeling procedure. In this paper, we review the recent advances in LSPR research and also describe the LSPR-based optical biosensor constructed with a core-shell dielectric nanoparticle biochip for its application to label-free biomolecular detections such as antigen-antibody interaction.

Enhancement of Anticancer Activity of Acer mono Aqueous Extracts by Nano-Encapsulation Process (고로쇠 수피 수용성 추출물의 나노입자화를 통한 항암활성 증진)

  • Kim, Ji-Seon;Jeong, Myoung-Hoon;Choi, Woon-Yong;Seo, Yong-Chang;Cho, Jeong Sub;Lee, Hyeon Yong
    • Journal of Korean Society of Forest Science
    • /
    • v.100 no.1
    • /
    • pp.14-24
    • /
    • 2011
  • Anticancer activity of Acer mono aqueous extracts was enhanced by nano-encapsulation process of gelatin. The cytotoxicity on human normal lung cell (HEL299) of the extracts from WE (water extract at 100) showed 23.51%, lower than that from NE (nano-encapsulatioin of water extract of Acer mono) in adding the maximum concentration of 1.0 mg/mL. NE showed more potent scavenging effect as 73.15% than the WE. On SOD-like test, the NE showed highest activity as 32.33% at 1.0 mg/mL concentration. Human stomach adenocarcinoma, liver adenocarcinoma, breast adenocarcinoma and lung adenocarcinoma cell growth were inhibited up to about 59-73%, in adding 1.0 mg/mL of NE. NE was 15% higher than conventional water extraction. Among several cancer cell lines (stomach adenocarcinoma, liver adenocarcinoma), the growth of digestive related cancer cells were most effectively inhibited as about 71-73%. The size of nano particles was in the ranges of 100-200 nm, which can effectively the penetrate into the cells, it was observed by real time confocal microscope. It tells that the aqueous extracts of Acer mono bark could be definitely enhanced by nano-encapsulation process.