• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.27 no.1
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• pp.117-129
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• 2014

Objective : To study current status on characteristics of allergic rhinitis patients by using the electronic medical record (EMR) data and to explore the feasibility of clinical studies using the EMR data in three different Korean medical hospitals. Methods : We studied allergic rhinitis patients who visited the department of ophthalmology, otolaryngology and dermatology in the three different Korean hospitals from January 1, 2012 to December 31, 2012. We retrospectively collected medical history and characteristics of study subjects using data of EMR. Results : In hospital A, we were able to collect data of 18 years of age or older. In hospital C, we could only collect data after July 1, 2012. Therefore, each hospital's data had different settings in measuring them. Men and women were accounted for similar percentage, and teens were the highest in the age group. J30.4, unspecified allergic rhinitis, was the highest in diagnosis of the allergic rhinitis. Most of the patients have received acupuncture treatments. Moreover, 74.6 percent of the total patients were prescribed with Chinese medicine. Conclusions : Based on this exploratory study, further studies were needed on clinical studies using data of systematic EMR.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.26 no.2
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• pp.10-18
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• 2013

Objectives : We performed a pilot study to investigate inter- and intra-rater reliability of pattern identification using nasal endoscopy for allergic rhinitis(AR). Methods : Eight experts of ophthalmology, otolaryngology and dermatology of Korean medicine evaluated 20 nasal endoscopy photograph cases of AR patients with pattern identification index using nasal endoscopy for AR including the nasal membrane color(pale / hyperemia), nasal membrane humidity(dryness / dampness), rhinorrhea(watery / yellow), and membrane edema (atrophic / edematous) on nasal endoscopy. Results : Intra-rater agreement(%) and Kappa coefficient was generally from 'moderate' to 'good'(% agreement: 73.13-90% / Kappa coefficient: 0.547-0.748). Inter-rater agreement(%) and Kappa coefficient was also from 'moderate' to 'good' (% agreement: 65-85% / Kappa: 0.475-0.778) except 'humidity(dryness / dampness)' item (% agreement: 55.98% / Kappa: 0.340). In findings of subgroup analysis according to affiliation of raters, Inter-rater agreement(%) and Kappa coefficient of raters in same affiliation was higher than inter-rater agreement(%) and Kappa coefficient of raters in different affiliation except 'dryness / dampness' item. Conclusions : It is necessary to improve objectivity and reproducibility of pattern identification using nasal endoscopy for allergic rhinitis(AR) through the development of detail-oriented criteria and enhanced training of clinicians with development of standard operating procedures(SOPs).

• Journal of Plant Biotechnology
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• v.41 no.1
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• pp.10-18
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• 2014

Seed oils (triacylglycerols) of plants are used as a source of essential fatty acids and nutrition for human. In addition, triacylglycerols have been used as industrial raw materials and biofuels. Triacylglycerols are mainly accumulated in seeds by complicated biochemical pathways. Fatty acids are synthesized in the plastids and transported into the endoplasmic reticulum for synthesizing triacylglycerols. It is known for a long time that biosynthesis of triacylglycerols is performed by a de novo synthesis, the Kennedy pathway. However recent studies have revealed that phosphatidylcholine, a major component of cell membrane, plays a central role for triacylglycerols biosynthesis. Phosphatidylcholine is a key regulator determining the relative proportions of unsaturated fatty acids in seeds. It may be a major carrier for the fluxes of fatty acids from the plastid to the endoplasmic reticulum. This finding further suggests that studies of the functions of enzymes involved in the fluxes of fatty acids from phosphatidylcholine to triacylglycerols elucidate the specialized subdomains in the endoplasmic reticulum for triacylglycerols biosynthesis.

• Korean Journal of Food Science and Technology
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• v.34 no.4
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• pp.637-641
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• 2002

The purpose of this study was to provide the basic information on the cookies made with garlic and to investigate quality characteristics of them using chemical and sensory evaluation of cookies. Cookie samples were prepared with shredded garlic at varied levels of 0, 3, 6 and 9%. The pH of the dough significantly decreased by the addition of garlic. Dough density of control showed significantly lower values than those of 3% added sample groups. Spreadability of control had significantly higher values than the other samples. Texture measurement showed that the addition of garlic had no significant effect on cookie texture. Sensory evaluation resulted that the properties of crack, garlic aroma, garlic taste and brittleness of cookies tended to increase as the addition levels of garlic were increased. The cookies with 3% and 6% garlic had similar or significantly higher acceptance scores in all of the properties examined than those of control.

• Resources Recycling
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• v.21 no.2
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• pp.3-8
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• 2012

In the points of the environmental conservation and the recirculating utilization of limited resources, it is very important to recover valuable metals like Au, Ag, Pd, Cu, Sn, Ni, Co, and Li used as industrial raw materials from urban ores. From now, many processes have been developed for recovering the valuable metals contained in urban ores and some of them have been operated commercially. In the paper, pyrometallurgical processes developed for reclaiming valuable metals from urban ores will be briefly introduced.

• Resources Recycling
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• v.26 no.4
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• pp.88-94
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• 2017

The recovery of gold in cyclone type electrolytic cell was conducted from solution for stripping gold of PCB by cyanide. The electrolytic recovery behaviors of gold was investigated by reaction time and addition of electrolytic sodium hypochlorite (NaOCl) and gold plating additive (KG-120). Because the electrolysis generated NaOCl reacted with the cyanide in the leachate by alkaline chlorination, more than 99% of the cyanide was removed at a $NaOCl(g)/CN^-(g)$ ratio of 1.0. When NaOCl was added during the recovery of the gold from cyanide leachate in the cyclone electrolytic cell, the recovery of gold was 98% at the ratio of $NaOCl(g)/CN^-(g)$ from 0.5 to 2.5 in 480 minutes and decreased rapidly over the ratio of 3.0. Gold was recovered more than 99% by adding 1.5 and 4.5%(v/v) of KG-120 with NaOCl in 480 minutes. In particular, when the concentration of KG-120 was 3.5 and 4.5%(v/v), more than 96% of gold was recovered within 240 minutes and the initial recovery rate was relatively faster. The optimum concentration of KG-120 is 3.5%(v/v) considering the economic feasibility and efficiency.

• Journal of Yeungnam Medical Science
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• v.23 no.1
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• pp.62-70
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• 2006

Background: Benign prostatic hyperplasia (BPH) is the most common benign tumor in older men; the etiology of this disease remains poorly understood. Testosterone and dihydrotestosterone (DHT) both act as androgen via a single androgen receptor. Testosterone is converted to DHT by $5{\alpha}$-reductase in prostatic stromal cells. Progesterone has been reported to inhibit DHT conversion; howevwe, its effect on prostatic stromal cells remains to be elucidated. Materials and Methods: In this experiment, we investigated the effect of progesterone on androgen receptor expression induced by DHT. We also tested the effect of progesterone on cyclooxygenase-2 (COX-2) expression, as well as prostate stromal cell proliferation using the cell count kit-8. Results: Progesterone did not cause an increase of prostate stromal cell proliferation. The mRNA expression of the androgen receptor and COX-2 were not changed by progesterone; the expressions of androgen receptor and COX-2 proteins were decreased by progesterone in prostate stromal cells. Conclusion: These results suggest that in prostate stromal cells, progesterone decreases androgen receptor protein expression, which results in decrement of COX-2 protein expression. This effect might be mediated by post-transcriptional regulation.

• Journal of Yeungnam Medical Science
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• v.12 no.2
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• pp.260-268
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• 1995

Ischemia results when the decrease in tissue perfusion exceeds the tissues ability to increase an oxygen extraction from the blood. Brain edema has been defined as an abnormal accumulation of fluid within brain parenchyma associated with a volumetric enlargement of the brain tissue. In most instances, the labelling of edema as vasogenic or cytotoxic is only relative. For cerebral protection, there were many possible techniques which could increase or maintain cerebral perfusion and reduce cerebral metabolic demand for oxygen. This study was carried out the effect of mild brain hypothermia which was induced by infusion with cold saline into the carotid artery, during brief episodes of transient global ischemia on postischemic brain edema in rabbit. Eight rabbits were anesthetized with halothane and mechanically ventilated with oxygen. For isolated cerebral perfusion, polyethylene catheter was inserted left carotid artery for infusion of cold saline, external carotid artery was ligated, vertebral arteries were cautherized, right carotid artery was snared for ischemia and femoral artery and vein were also canulated for monitoring and drug treatment. At 3 hours After transient global ischemia, specific gravity of cerebral cortex and hippocampus was compared with no-perfusion group , perfusion with cold saline group and normal group. There was no significant differences in physiologic variables among the groups before transient global ischemia. But during transient global ischemia, brain temperature of perfusion group was decreased when compared to no perfusion group. Specific gravity of cerebral cortex and hippocampus of no-perfusion group and perfusion group was statistically significant when compared to normal group (p<0.01). The results of this study suggested that mild brain hypothermia with intracarotid cold saline infusion during brief episodes of transient global ischemia had decreased postischemic brain edema in rabbit.

• Proceedings of the Korea Water Resources Association Conference
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• 2015.05a
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• pp.114-114
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• 2015

최근 기후변화로 인해 지구촌 곳곳은 이전에 경험하지 못한 극한 홍수재해로 몸살을 앓고 있다. 2011년 태국에서는 짜오프라야강 범람으로 국토의 70% 이상이 침수되었고, 2013년 인도 북부지역에서는 갠지스강 및 지류의 범람, 산사태, 가옥붕괴 등으로 1,000여명이 숨지고 관광객 및 순례객 7만여명의 발이 묶이는 피해가 발생하였으며, 2014년 발칸반도에서는 120년만의 폭우로 인하여 30여명이 사망하고 100만명의 이재민이 발생하였다. 국내의 경우 2011년 수도권을 중심으로 하루에 300mm가 넘는 기록적 호우가 쏟아지면서 주택과 도로의 침수, 산사태 등으로 많은 인명 및 재산피해가 발생하였다. 또한 2014년 8월 경남 부산지역에는 시간당 130mm가 넘는 국지성 호우에 따른 산사태, 침수 등으로 도심기능이 마비되는 피해가 발생하기도 하였다. 이처럼 대부분의 자연재난은 태풍 및 집중호우 등 물재해로 발생하고 있으며, 국내의 경우 2012년 전체 자연재난의 95.6%, 2013년 전체 자연재난의 93%를 물재해가 차지하였다. 이에 구조적 비구조적 홍수 재해 저감대책 수립 및 시행 등 지속적인 물관리 노력으로 대하천에서 발생하는 홍수피해는 크게 감소하였으나, 지자체를 중심으로 운영 관리되고 있는 중소하천에서의 피해는 오히려 점차 증가하고 있다. 조사에 따르면 최근 5년간(2007~2011) 홍수피해의 98% 이상이 중소하천을 중심으로 발생한 것으로 발표된 바 있다. 특히 지자체의 경우 전문인력 및 기술력 부족, 열악한 재정 등으로 피해가 반복되고 있는 실정이다. 이에 따라 중소하천과 같이 소외된 지역의 물복지 향상을 위해서는 홍수재해 상황에 신속하고 효과적으로 대응하기 위한 과학적 체계적인 선진 홍수재해 관리체계의 구축이 요구되는 바이다. 이에 물관리 전문기관인 K-water에서는 지난 2010년부터 ICT기반의 우수한 물관리 기술력과 홍수대응 Know-How를 활용하여 '지자체 맞춤형 홍수재해관리시스템' 구축을 지원하고 있다. 본 시스템은 상 하류의 다양한 재난 정보를 수집 통합하고, 수집된 정보를 활용한 홍수분석을 통해 예방적 재난대응 체계를 구축하는 것으로, K-water는 지난 2010년 남원시를 시작으로 무주군, 군산시, 진안군 등의 시스템 구축을 지원하고 있다. 재난은 복구보다 예방이 우선되어야 함은 모두 다 아는 사실이지만 예산문제 등으로 항상 소 잃고 외양간 고치는 일이 아직까지 반복되고 있다. K-water는 물관리 전문 공기업으로써의 역할을 다하고, 예방 위주의 재난관리 체계 마련을 위해 '지자체 맞춤형 홍수재해관리시스템' 구축 지원을 지속적으로 확대해 나갈 것이다.

• The Journal of Korean Obstetrics and Gynecology
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• v.20 no.3
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• pp.200-212
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• 2007

Purpose: To find objective validity of minimal acupuncture using a modified guide tube as a method to verify the effect of acupuncture. Methods: Subjects of this study were participants of a randomized clinical trial which was practiced to verify the effect of acupuncture on postmenopausal hot flash. There were 2 arms of treatment, one's for active acupuncture group(AG) with manipulation and De qi, the other's for minimal acupuncture group(MG) using a modified guide tube which was designed to give minimal stimulation to the patient. After 8 weeks' treatment followed by 4 weeks' observation, participants were asked to fill in self-report forms on their education, previous experiences of acupuncture, original idea on the efficacy of acupuncture and recognition of blinding. Results: 19 participants of 26 in AG and 19 of 26 in MG completed the self-report form. There was no difference between AG and MG in their education(p=0.5976, Fisher exact test) and previous experiences of acupuncture(p=0.9999, Fisher exact test). In their original ideas on the efficacy of acupuncture, most of AG and MG respondents have been thought that acupuncture is very effective or quite effective, and there was no difference between 2 groups(p=0.5065). 16 of 19 in AG and 14 of 19 in MG believed that they underwent more effective way, there was no statistical difference between 2 groups(p=0.6928, Fisher exact test). Participants believed in undergoing more effective way not because they recognized treatment method, but they were satisfied with the effectiveness of treatment retrospectively. Conclusion: As the result of this study, these authors suggest that minimal acupuncture using a modified guide tube is acceptable as a method to verify the effect of acupuncture in acupuncture-familiar Korean culture. Also further studies on the stimulation-specific effect of minimal acupuncture are demanded.