• Title/Summary/Keyword: 기초의학

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Associations of Illness Symptoms, Perception of Illness, and Coping with Quality of Life of Thyroid Cancer Patients after Thyroidectomy (갑상선절제술을 받은 갑상선암 환자의 질병증상, 질병인식, 대처와 삶의 질과의 관련성)

  • Hyun, Jae Won;Song, Hyo Jeong;Choi, Jae Hyuck
    • Journal of Korean Biological Nursing Science
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    • v.23 no.1
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    • pp.83-90
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    • 2021
  • Purpose: To determine associations of illness symptoms, perception of illness, coping with quality of life (QOL) of thyroid cancer patients and identify factors affecting their QOL. Methods: A cross-sectional study was performed using a self-administered questionnaire for 111 thyroid cancer patients after thyroidectomy. They were recruited from the outpatient clinic of one university hospital. Data collection was conducted from August 2018 to November 2018. Results: The QOL was significantly associated with interpersonal coping (β= 0.31, p< .001), monthly household income (β= 0.30, p< .001), illness symptoms (β= -0.22, p= .017), perception of illness (β= -0.20, p= .031), and education (β= 0.18, p= .037) in stepwise multiple regression. These factors explained 33.1% of QOL of thyroid cancer patients. Conclusion: Interpersonal coping is a major contributing factor to QOL. Therefore, thyroid cancer patients need good interpersonal coping for better quality of life.

Ai-Based Cataract Detection Platform Develop (인공지능 기반의 백내장 검출 플랫폼 개발)

  • Park, Doyoung;Kim, Baek-Ki
    • Journal of Platform Technology
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    • v.10 no.1
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    • pp.20-28
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    • 2022
  • Artificial intelligence-based health data verification has become an essential element not only to help clinical research, but also to develop new treatments. Since the US Food and Drug Administration (FDA) approved the marketing of medical devices that detect mild abnormal diabetic retinopathy in adult diabetic patients using artificial intelligence in the field of medical diagnosis, tests using artificial intelligence have been increasing. In this study, an artificial intelligence model based on image classification was created using a Teachable Machine supported by Google, and a predictive model was completed through learning. This not only facilitates the early detection of cataracts among eye diseases occurring among patients with chronic diseases, but also serves as basic research for developing a digital personal health healthcare app for eye disease prevention as a healthcare program for eye health.

Assessing Hematological Change Associated with Cardiovascular Disease Risk among Korean Taxi Drivers Using Data from the Second (2012-2014) Korean National Environmental Health Survey: A Propensity Score Matching Approach (제2기(2012-2014) 국민환경보건 기초조사 자료를 활용한 국내 남성 택시 기사의 심혈관계 위험도 관련 혈액학적 변화에 대한 연구: 성향점수 매칭을 활용하여)

  • Baek, Kiook
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.31 no.4
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    • pp.367-377
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    • 2021
  • Objectives: Taxi drivers are exposed to various hazards, such as long periods of sedentary work and traffic-related air pollutants. However, studies on the health effects among taxi drivers in South Korea are insufficient. Methods: To assess subclinical hematologic change related to cardiovascular disease among male taxi drivers, we analyzed data from the second Korean National Environmental Health Survey. Fifty-nine taxi drivers and 1,912 controls were included in the analysis. Propensity score matching was performed to adjust for age, body mass index, and urinary cotinine. A total of 295 subjects were matched with 59 taxi drivers. Leukocyte count, platelet count, hematocrit, triglyceride, total cholesterol, HDL cholesterol land total IgE of the taxi drivers were compared with the control groups. Results: Taxi drivers showed significantly elevated blood leukocytes and platelets. Serum total IgE was significantly reduced in taxi drivers. However, blood leukocytes, platelets, and serum total IgE were not significantly correlated with work period among taxi drivers. Conclusions: Regarding the change of the blood leukocyte count, platelet count, and serum total IgE, taxi driving has the possibility to be associated with peripheral inflammation, humoral immunity and cardiovascular risk.

Safety in Mass Gathering: Basic Survey for Crowd Crush (군중집회 시의 안전: 군중압박의 기초 조사)

  • Soon-Joo Wang
    • Journal of Korean Society of Disaster and Security
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    • v.16 no.1
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    • pp.49-60
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    • 2023
  • After the 10.29 Itaewon disaster, interests in the crowd crush injury increased, but it is pointed out that the academic and practical basis related to crowd crush is still weak in Korea. Therefore, in this study, terms and concepts related to crowd crush were investigated and proposed, and representative cases of crowd crush events were investigated and summarized. Approaches based on representative cases were investigated, and among them, video analysis, simulation, questionnaire survey and interview methods were derived as an essential approach methods. Through this research, it is expected that standardization of Korean terminology, concept establishment, evaluation, and systematization of approach methods of crowd crush can be accomplished.

Circulating Tumor Marker (순환 종양 표지자)

  • Sung Yong Han;Dong Uk Kim
    • Journal of Digestive Cancer Research
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    • v.6 no.2
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    • pp.59-63
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    • 2018
  • Over the past decade, circulating tumor cell have received tremendous attention as new biomarkers and basic research subjects.In recent years, research on circulating tumor DNA, exosomes and microRNAs has also been actively conducted.These circulating tumor markers have the potential to become the basis of precision medicine, such as determining the genome / immune profile, monitoring response and tolerance, and selecting therapeutic agents beyond the early diagnosis and prognosis prediction.In this article, we introduce the diagnostic methods, efficacy, meaning, and applicability of various circulating tumor markers.

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Characterization of typical Aeromonas salmonicida isolated from Sea-Chum Salmon (Oncorhynchus keta) (해수에 순치된 첨연어(Oncorhynchus keta)에서 분리된 정형 에로모나스 살모니시다(Aeromonas salmonicida)에 대한 특성 분석)

  • Jongwon Lim;Sungjae Ko;Youngjun Park;Do-il Ahn;Suhee Hong
    • Journal of fish pathology
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    • v.36 no.2
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    • pp.263-275
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    • 2023
  • Chum salmon (Oncorhynchus keta) is a species which returns to Korea for spawning and was produced as seed production at the Fisheries Resources Agency located in Uljin-gun, Gyeongsangbuk-do to preserve the species. However, farmed chum salmon showed symptoms of bacterial infection. Therefore, in this study, bacteria were isolated to identify the causative agent from chum salmon in October 2021. The isolated bacteria were identified based on the sequences of 16S rDNA, rpoD (RNA polymerase sigma factor σ70), and vapA (A-layer) genes. Also, salinity-growth curve, biochemical characterization, antibiotic susceptibility test, and pathogenicity analysis were performed in four strains. As a result, four isolated strains were identified as Aeromonas salmonicida subsp. salmonicida. Additionally, the bacterial strains showed a decrease in growth as the salt concentration increased in the medium. All of the isolated strains exhibited γ-hemolysis, and the same biochemical properties. In the antimicrobial susceptibility test, all strains showed an inhibition zone of 40 to 44 mm for oxolinic acid, flumequine, and florfenicol. Pathogenic factors were assessed by RT-PCR at the mRNA level, and found that the four strains expresses the outer membrane ring of T3SS (ascV), inner membrane ring of T3SS (ascC), vapA, enterotoxin (act), and lipase (lip) genes which are well known to significantly contribute to the pathogenicity of A. salmonicida. The results of this study can be used as basic data to prevent A. salmonicida subsp. salmonicida occurring in sea-chum salmon in the future.

Effect of a Qigong-Based Stress Management Program on Emotion of Pregnant Women (기공에 기초한 스트레스 관리 프로그램이 산모의 정서에 미치는 영향)

  • Lee, Sang-Hyuk;Kim, Mu-Jin-Haeng;Lee, Eun-Hee;Suh, Shin-Young;Yook, Ki-Whan;Choi, Tae-Kyou
    • Korean Journal of Psychosomatic Medicine
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    • v.12 no.2
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    • pp.135-144
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    • 2004
  • Objectives: The aim of this study was to examine the effectiveness of a qigong-based stress management program in pregnant women. Method: A 8 week controlled clinical trial compared 52 pregnant women assigned qigong-based stress management program to 40 pregnant women assigned pregnancy health education program. Edinburgh postnatal depression scale(EPDS), Beck depression inventory(BDI), Spielberger trait state inventory-1(STAI-1), Hamilton depression rating scale(HAM-D), Hamilton anxiety scale(HAM-A) were used to measure anxiety and depression level. Result : Qigong-based stress management group showed significant improvement compared to the education control group on four measures above. Qigong-based stress management group also showed significant improvement at 8 weeks termination on all measures of anxiety and depression compared to pretreatment level. Conclusion : This study showed that qigong-based stress management program can be an effective method for pregnant women.

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EVALUATION OF THE THERAPEUTIC EFFECTS OF CARBAMAZEPINE IN AUTISTIC CHILDREN (자폐증 아동에 있어서 Carbamazepine의 치료효과 평가)

  • Hong, Kang-E;Choi, Jin-Sook;Shin, Min-Sup;Hwang, Yong-Seung;Ahn, Yun-Ok
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.2 no.1
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    • pp.87-96
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    • 1991
  • A double bhad, placebo controlled study was performed to evaluate the therapeutic effects of Carbamazepine in autistic children, 23 boys with the diagnosis of Pervasive Developmental Disorders according to the DSM-IIIR were selected for study subjects, from Child and Adolescent Psychiatric Outpatient Department of Seoul National University Children Hospital during Oct. $1989{\sim}Nov.$ 1991. Subjects with histories of medical disease or psychiatric diseases were excluded and all study subjects had drug free periods more than 2 Months. Study subjects were randomly assigned to Cabamazepine treatment group(N=12) and placebo group(N=11). After the baseline observation periods, the double blind drug treatment and observation were performed for 12 weeks. Several scales (Ritvo-Freedman Real Life atring Scale. Behavior Checklist) were employed to evaluate the effects of drug treatment during baseline observation periods and the drug treatment periods by two raters blind to the study. Interrater reliability of each scales were .4875~.6613, the socrodemographic variables and the rating scores during baseline observation periods were not significantly different between two groups. Reduction of total scores in Autsm Behavior Checklist scale, i.e.. improvement of global autistic symptoms were noted significantly in Carbamazepine treatment group. Improvement in significant social maturations according to Vineland Social Mataration scale were observed in both patient groups after drug treetment periods.

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KNEE: Basic Science and Injury of Bone (슬관절 주위 글격의 기초과학 및 스포츠 손상)

  • Kim Hee-Chun
    • Journal of Korean Orthopaedic Sports Medicine
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    • v.2 no.2
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    • pp.77-81
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    • 2003
  • Purpose: The biomechanics and kinematics of knee joint were reviewed in this article. And then the common sports injuries were presented. Anatomy and Kinetics: None of the pairs of bearing surfaces in the knee joint is exactly congruent This allows the knee six degrees of freedom of motion. Tibiofemoral Kinematics: In flexion and extension, the axis of motion is not perpendicular to the medial-lateral plane of the joint, nor is it perpendicular to the axis of longitudinal rotation. This results in coupled varus angulation and internal rotation with flexion and in valgus angulation and external rotation with extension. Patellofemoral Articulation: Loads across the patellofemoral joint are indirectly related to the angle of knee flexion and directly related to the force generated within the quadriceps mechanism. Fractures of the Patella: Nonoperative treatment is indicated if the extensor mechanism is intact and if displacement of fragment is minimal. The specific type of internal fixation depends on the fracture pattern. It is important to repair retinaculum. Acute and Recurrent Patellar Instability: The degree of dysplasia and the extent of the instability play a large part in determining the success of nonoperative treatment. Patients who experience recurrent dislocations and patients with major anatomic variations require surgery to minimize their instability. Sports Injuries in School-age Atheletes: Patellar pain in young athletes groups a number of conditions, including Idiopathic Adolescent Anterior Knee Pain, Osgood- Schlatter Disease, and Sinding-Larsen-Johansson Disease.

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A Survey on the Demand of Education topic for the Development of Dental Hygienist Coordination System (Dental Hygienist Coordination System 개발 교육주제 요구조사)

  • Lee, Yun-Jung;Woo, Hee-Sun
    • Journal of dental hygiene science
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    • v.10 no.5
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    • pp.349-356
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    • 2010
  • The purpose of this study was to examine the awareness of dental hygienists, who played a significant role in dental sector, about health care management and their needs for education in an attempt to pave the way for the development of a Dental Hygienist Coordination System(DHCS). The subjects were 156 dental hygienists at 85 dental clinics, who were selected in Gwangju based on the data released as of August 2008 by the Dental Association and public health centers in sampling region. A Questionnaire was conducted in person to gather survey data and SPSS 12.0 program was utilized to make a statistical analysis. This results findings suggested that a systematic curriculum should be developed by focusing on coordination theory and practice, counseling and educational practice, health insurance affairs and health insurance fee claim management.