Recently, research on applying text analysis to deep learning has steadily continued. In particular, researches have been actively conducted to understand the meaning of words and perform tasks such as summarization and sentiment classification through a pre-trained language model that learns large datasets. However, existing pre-trained language models show limitations in that they do not understand specific domains well. Therefore, in recent years, the flow of research has shifted toward creating a language model specialized for a particular domain. Domain-specific pre-trained language models allow the model to understand the knowledge of a particular domain better and reveal performance improvements on various tasks in the field. However, domain-specific further pre-training is expensive to acquire corpus data of the target domain. Furthermore, many cases have reported that performance improvement after further pre-training is insignificant in some domains. As such, it is difficult to decide to develop a domain-specific pre-trained language model, while it is not clear whether the performance will be improved dramatically. In this paper, we present a way to proactively check the expected performance improvement by further pre-training in a domain before actually performing further pre-training. Specifically, after selecting three domains, we measured the increase in classification accuracy through further pre-training in each domain. We also developed and presented new indicators to estimate the specificity of the domain based on the normalized frequency of the keywords used in each domain. Finally, we conducted classification using a pre-trained language model and a domain-specific pre-trained language model of three domains. As a result, we confirmed that the higher the domain specificity index, the higher the performance improvement through further pre-training.
The timely procurement of military supplies is essential to maintain the military's operational capabilities, and contract work is the first step toward timely procurement. In addition, rapid signing of a contract enables consumers to set a leisurely delivery date and increases the possibility of budget execution, so it is essential to improve the contract process to prevent early execution of the budget and transfer or disuse. Recently, research using big data has been actively conducted in various fields, and process analysis using big data and process mining, an improvement technique, are also widely used in the private sector. However, the analysis of contract work in the military is limited to the level of individual analysis such as identifying the cause of each problem case of budget transfer and disuse contracts using the experience and fragmentary information of the person in charge. In order to improve the contract process, this study analyzed using the process mining technique with data on a total of 560 contract tasks directly contracted by the Department of Finance of the Air Force Logistics Command for about one year from November 2019. Process maps were derived by synthesizing distributed data, and process flow, execution time analysis, bottleneck analysis, and additional detailed analysis were conducted. As a result of the analysis, it was found that review/modification occurred repeatedly after request in a number of contracts. Repeated reviews/modifications have a significant impact on the delay in the number of days to complete the cost calculation, which has also been clearly revealed through bottleneck visualization. Review/modification occurs in more than 60% of the top 5 departments with many contract requests, and it usually occurs in the first half of the year when requests are concentrated, which means that a thorough review is required before requesting contracts from the required departments. In addition, the contract work of the Department of Finance was carried out in accordance with the procedures according to laws and regulations, but it was found that it was necessary to adjust the order of some tasks. This study is the first case of using process mining for the analysis of contract work in the military. Based on this, if further research is conducted to apply process mining to various tasks in the military, it is expected that the efficiency of various tasks can be derived.
Cho, Sehee;Lee, Seung-Hoon;Kim, Seonjeong;Cheong, Yucheol;Kim, Yewon;Kim, Ju Won;Kim, Su Jeong;Seo, Seungin;Seo, Dong-Won;Lim, Jae-Hwan;Jeon, Sejin;Jang, Yo Han
Journal of Life Science
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v.32
no.12
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pp.919-928
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2022
As seen in the COVID-19 pandemic, unexpected emergence of new viruses presents serious concern on public health. Especially, the absence of effective vaccines or antiviral drugs against emerging viruses significantly increases the severity of disease and duration of viral circulation among population. Natural products have served as a major source for safe and effective antiviral drugs. In this study, we examined the virucidal activity of medical herb extracts with a view to discover novel antiviral agents with desired levels of safety and antiviral efficacy. Ethanol extracts of ten selected medical herbs were tested for antioxidant activity and in-vitro cytotoxicity in various animal cell lines. Of note, the herbal extracts showed broad and potent virucidal activities against rotavirus, hepatitis A virus, and influenza A virus. The extracts of Sorbus commixta and Glycyrrhiza uralensis showed strong virucidal activities against influenza A virus. We also examined whether the extracts of Sorbus commixta and Glycyrrhiza uralensis can be used as inactivating agents to prepare an inactivated viral vaccine. In a mouse model, influenza A virus inactivated by the extracts elicited high levels of neutralizing antibodies, and the vaccination provided complete protection against lethal challenge. These results suggest that herb-derived natural products can be developed to antiviral drugs as well as inactivating agents for preparation of inactivated viral vaccines.
Park, Jong Woo;Park, Jeong Sun;Jeong, Chan Young;Kwon, Hyeok Gyu;Kang, Sang Kuk;Kim, Seong-Wan;Kim, Nam-Suk;Kim, Kee Young;Kim, Iksoo
Journal of Life Science
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v.32
no.12
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pp.947-955
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2022
Silkworms, which have recently shown promise as functional health foods, show functional differences between varieties; therefore, the need for variety identification is emerging. In this study, we analyzed the whole silkworm genome to identify 10 unique silkworm varieties (Baekhwang, Baekok, Daebaek, Daebak, Daehwang, Goldensilk, Hansaeng, Joohwang, Kumkang, and Kumok) using single nucleotide polymorphisms (SNP) present in the genome as biomarkers. In addition, nine SNPs were selected to discriminate between varieties by selecting SNPs specific to each variety. We subsequently created a decision tree capable of cross-verifying each variety and classifying the varieties through sequential analysis. Restriction fragment length polymorphism (RFLP) was used for SNP867 and SNP9183 to differentiate between the varieties of Daehwang and Goldensilk and between Kumkang and Daebak, respectively. A tetra-primer amplification refractory (T-ARMS) mutation was used to analyze the remaining SNPs. As a result, we could isolate the same group or select an individual variety using the nine unique SNPs from SNP780 to SNP9183. Furthermore, nucleotide sequence analysis for the region confirmed that the alleles were identical. In conclusion, our results show that combining SNP analysis of the whole silkworm genome with the decision tree is of high value as a discriminative marker for classifying silkworm varieties.
Jun, Do Youn;Woo, Hyun Joo;Ko, Jee Youn;Kim, Young Ho
Journal of Life Science
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v.32
no.12
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pp.929-937
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2022
To investigate the anti-inflammatory activity of the grains of sorghum, three Sorghum bicolor (L.) Moench variants (Hwanggeumchal, Huinchal, and Chal) being cultivated in Korea, the 80% ethanol (EtOH) extracts of individual sorghum grains were compared for their inhibitory activity against nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated RAW264.7 murine macrophage cell line. Among them, the EtOH extract of sorghum Hwanggeumchal grains could exert the highest inhibitory effect on the LPS-induced NO production. However, under these conditions, the viability of RAW264.7 cells was not affected. When the EtOH extract of sorghum Hwanggeumchal grains was sequentially fractionated with n-hexane, methylene chloride (MC), ethyl acetate (EtOAc), and n-butanol, the anti-NO production activity was predominantly detected in both MC and EtOAc fractions. In particular, treatment with the MC fraction reduced dose-dependently the expression levels of iNOS, COX-2 and pro-inflammatory cytokines (IL-1β, IL-6, and TNF-α) in LPS-stimulated RAW264.7 cells. Simultaneously, the MC fraction could prevent LPS-induced activating phosphorylation of p38 mitogen-activated protein kinase (MAPK), c-Jun N-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK). HPLC analysis of the MC fraction showed gentisic acid and naringenin as the major phenolic components. Both gentisic acid and naringenin commonly exhibited a potent inhibitory activity against LPS-induced NO production in RAW264.7 cells. Together, these results provide the evidence of the inhibitory activity of Hwanggeumchal grains on LPS-induce inflammatory responses in RAW264.7 murine macrophage cells and also suggest that sorghum grains possess beneficial health effects which can be applicable in development of the grain-based functional foods.
The purpose of this study was to validate the Korean Implementation Fidelity Checklist of Tier 1 School-Wide Positive Behavior Support (KIFC-T1) for use in the Korean educational system. Tier 1 support, which is universal supports, within a multi-tiered, school-wide positive behavior support (SWPBS) model, aims to provide support to and prevent problem behaviors among all students in a school. The initial KIFC-T1 consisted of 48 items and 11 factors and was developed based on a literature review. Its content was validated by experts. The validated KIFC-T1 was introduced to 185 special school teachers who had experience implementing SWPBS and who used the instrument to assess the degree to which their schools had implemented Tier 1 support. Based on their responses, the construct validity of the KIFC-T1 was examined using factor, item, and internal consistency reliability analyses. The concurrent validity of the tool was examined using the PBS Evaluation Tool, School Climate Questionnaire, School Discipline Practice Scale, and PBS Effectiveness Scale. The analyses revealed that KIFC-T1 had a stable five-factor structure with 35 items, had good reliability (Cronbach's α=.956, each factor's Cronbach's α=.834-.951), and its results were statistically significantly correlated with those of the PBS Evaluation Tool, School Discipline Practice Scale, and the PBS Effectiveness Scale. However the KIFC-T1's results were not statistically significantly correlated with the results of the School Climate Questionnaire. These results suggest that KIFC-T1 is a reliable and valid tool for assessing the fidelity of universal support implementations.
Due to river maintenance projects such as the creation of hydrophilic areas around rivers and the Four Rivers Project, the flow characteristics of rivers are continuously changing, and the risk of water quality accidents due to the inflow of various pollutants is increasing. In the event of a water quality accident, it is necessary to minimize the effect on the downstream side by predicting the concentration and arrival time of pollutants in consideration of the flow characteristics of the river. In order to track the behavior of these pollutants, it is necessary to calculate the diffusion coefficient and dispersion coefficient for each section of the river. Among them, the dispersion coefficient is used to analyze the diffusion range of soluble pollutants. Existing experimental research cases for tracking the behavior of pollutants require a lot of manpower and cost, and it is difficult to obtain spatially high-resolution data due to limited equipment operation. Recently, research on tracking contaminants using RGB drones has been conducted, but RGB images also have a limitation in that spectral information is limitedly collected. In this study, to supplement the limitations of existing studies, a hyperspectral sensor was mounted on a remote sensing platform using a drone to collect temporally and spatially higher-resolution data than conventional contact measurement. Using the collected spatio-temporal hyperspectral images, the tracer concentration was calculated and the transverse dispersion coefficient was derived. It is expected that by overcoming the limitations of the drone platform through future research and upgrading the dispersion coefficient calculation technology, it will be possible to detect various pollutants leaking into the water system, and to detect changes in various water quality items and river factors.
Soil(vadose zone) gas compositions were measured for about 3 days to suggest a method for monitoring and interpreting soil gas data collected around wells from which methane(CH4) is outflowing. The vadose zone gas samples were collected within 1 m around two test wells(TB2 and TB3) at Pohang and analyzed for CO2, CH4, N2 and O2 concentrations in situ. CO2 flux was measured beside TB2. In addition, gas samples from well head in TB2 and atmospheric air samples were collected for comparison. Carbon isotopes of CO2(δ13CCO2) of samples collected on the last day of the study period were analyzed in the laboratory. The two test wells (TB2 and 3) were 12.7 m apart and only TB3 was cemented to the surface. According to the bio-geochemical process-based interpretation, the relationships between CO2 and O2, N2, and N2/O2 of vadose zone gas were plotted between the lines of CH4 oxidation and CO2 dissolution. In addition, the CH4 concentrations of gas samples from the wellhead of the uncemented well (TB2) were 5.2 times higher than the atmospheric CH4 concentration. High CO2 concentrations (average 1.148%) of vadose zone gas around TB2 seemed to be attributed to the oxidation of CH4. On the other hand, the vadose zone CO2 around the cemented well(TB3) showed a relatively low concentration(0.136%). This difference indicates that the vadose zone gas(including CO2) around the CH4 outflowing well were strongly affected by well completion(cementing). This study result can be used to establish strategies for environmental monitoring of soil around natural gas sites, and can be used to monitor leakage around injection and observation wells for CO2 geological storage. In addition, the method of this study is useful for soil monitoring in natural gas storage and oil-contaminated sites.
We investigated the emergence patterns of Chilo suppressalis (Lepidoptera: Crambidae) adults using sex pheromone traps in the three northeastern areas, Dandong (40°07'N 124°23'E) (Liaoning province), and Gongzhuling (43°30'N 124°49') and Longjing (42°46'N 129°26'E) (Jilin province), China, in 2020 and 2021. Two times of adult flight seasons were isolated clearly during the rice growing periods in the all areas, in which the first season from mid May to late July, and the second season from mid July to mid September were observed. The adult emergence seasons in the areas at higher latitude were later than that at lower latitude. Using the adult emergence data during the first flight seasons, the second flight seasons were estimated through insect phenology modelling, and compared with the observed data. Temperature-dependent life history models (developmental rate, development completion, survival rate, adult aging rate, total fecundity, oviposition completion, and adult survival completion) were collected or constructed for each life stage of C. suppressalis, in which the data from the four previous studies were used. Those models were combined in an insect phenology estimation software, PopModel, and operated for the observed areas. In the results, the phenology modelling operated with the models based on the data of shorter larval periods in the previous studies estimated more accurately the second flight seasons. In 2021, we investigated the change of damaged hill ratios of rice with observing the adult emergence at Dandong and Longjing, 2021. The increase periods of damaged hill ratios of rice were observed two times during the total rice cultivation season, which may be caused by different generations of C. suppressalis larvae.
This study compares and analyzes the Soil and Water Assessment Tool (SWAT) and Terra MODIS (Moderate Resolution Imaging Spectroradiometer) as coniferous, deciduous and mixed forest with Yongdam Dam upstream (904.4 km2). The hydrologic evaluation period was set to 10 years from 2010 to 2019, and the applicability of the 8-day MOD15A2 Leaf Area Index (LAI) data, 3 TDR (Time Domain Reflectometry) (GB, JC, CC), and 1 Flux Tower (DU) evaporation volume (YDD) data was simulated. As a result, the R2 of coniferous forest, deciduous forest and mixed forest are 0.95, 0.89, 0.90, soil moisture and evaportranspiration stations R2 were analyzed at 0.50 to 0.55 and 0.51, respectively, with R2 at 0.74, RMSE 2.75 mm/day, NSE 0.70 and PBIAS 14.3% for Yongdam inflow. Based on the calibrated and validated watersheds, the annual average evaportranspiration was calculated as coniferous 469.7 mm, deciduous 501. mm and 511.5 mm mixed forest, total runoff were estimated at coniferous 909.8 mm, deciduous 860.6 mm and 864.2 mm mixed forest. In the case of annual average evaportranspiration, it was evaluated that deciduous were high, but in the case of streamflow, it was evaluated that coniferous were high. Unlike other hydrologic with similar patterns throughout the year, the average annual evapotranspiration was about 7% higher than coniferous due to the higher evapotranspiration of deciduous with high leaf area index in summer and fall. In addition, deciduous were 9% and 6% higher for surface runoff and lateral flow, but the groundwater of coniferous was 77% higher. Therefore, it was confirmed that the total runoff was in order of coniferous, mixed forest, and deciduous.
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