• Title/Summary/Keyword: 근반응성

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관능에 관여하는 의식요소와 식품관능평가의 시간함수개념

  • 전재근
    • Proceedings of the Korean Society of Food Science and Nutrition Conference
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    • 2000.11a
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    • pp.115-123
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    • 2000
  • 식품의 관능검사는 인간의 의식과 식품간의 반응결과를 객관적으로 나타내는 방법으로 수치, 언어적 묘사, 도표 등의 표현법을 사용하고 있으며 검사 요원들 간의 오차를 발생한다. 이 오차를 줄이기 위하여 통계 및 심리학적으로 접근하여 해결을 시도해 오고 있으며 오차를 심리적 잡음 (psychological noise)이라고 주장되고 있다. 식품의 기호도는 감각신경세포에서 전기적 신호로 전환되어 뇌에 전달되고 의식의 분석과 해석을 거쳐 얻어지는 것이므로 전기적 신호처리가 포함된다. 그러나 현재의 관능검사 방법들은 시간의 함수관계를 중시하고 있지 않다. 감각신경의 신호 전달체계의 유사성을 바탕으로 관능검사과정에 시간함수를 도인하는 개념이 요구된다. 시간을 개입하는 방법론으로 의식과 식품간의 일어나는 순차적 또는 병열적 행동과 의식체계를 분석하고 시간인자의 중요성을 부각시켰다. 시간함수의 도입방법으로 관능영향인자 표의 구성하고 bar-code를 생성하는 프로그램과 파형곡선으로 전환하는 개념을 제안하였다.

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Flumethasone 투여후의 수의임상 관찰

  • McCormick J.E.
    • Journal of the korean veterinary medical association
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    • v.27 no.5
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    • pp.288-290
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    • 1991
  • 개의 여러가지 질병상태에서 근복적인 치료나 보조적인 치료제로서의 flumethasone 투여는 아주 좋은 치료효과를 나타냈다. 우리가 병원에서 상용하는 flumethasone의 평균 투여량은 0.125$\~$0.5mg으로서 경구 또는 주사로 투여했다. 경구적으로 투여하는 주된 사용량은 1일 0.03125mg$\~$0.125mg이며 환축의 크기, 치유과정 그리고 병증의 심한 정도에 따라 양을 가감했다. 투여경로를 달리하여도 약효에 차이가 생기지는 않았다. flumethasone의 소염효과, 당신생효과 및 항독소적 치료효과에서 기존의 corticoids 투여시 나타나는 효과에 비해 정성적인 차이는 없었으나 실험실 결과와 병원에서 사용한 임상결과 flumethasone은 hydrocortisone보다 300$\~$400배 그리고 prednisone이나 prednisolone 보다는 60$\~$80배나 강한 약효를 발휘하는 것으로 나타났다. 임상적용에서 나타난 감동적인 효과에서 이러한 flumethasone의 약효에 대한 자료들이 입증되었다. 또한 치료된 동물들이 보여준 반응은 flumethasone의 약효 지속시간이 기존의 corticoids보다 더 긴 것으로 나타났다. 앞에서 언급했듯이 flumethasone 투여시는 전해질 불균형에 의해 유발되는 다음다갈증이나 다뇨증, 식욕촉진 등의 부작용이 전혀 나타나지 않았다. 이러한 flumethasone의 안전성은 기존의 corticoids로 비만동물이나 나이든 환축을 치료할때 자주 나타났던 부작용업이 장기간 치료할 수 있으므로 아주 중요하다.

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Influence of $TiO_2$ Buffer Layer Thickness on the Electrical and Mechanical Properties of ITZO Films Deposited on Polymer Substrate (Polymer 기판위에 증착된 ITZO 박막의 $TiO_2$ 버퍼층 두께에 따른 전기적, 기계적 특성)

  • Gwon, Se-Hui;Kang, Yong-Min;Song, Pung-Geun
    • Proceedings of the Korean Institute of Surface Engineering Conference
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    • 2009.10a
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    • pp.195-196
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    • 2009
  • ITZO 박막과 $TIO_2$ 버퍼층은 각각 두 개의 캐소드를 사용한 마그네트론 2원동시 방전법과 산소 함량 2%를 사용한 반응성 sputtering 방법으로 각각 증착이 되었다. 모든 박막들은 상온에서 폴리머 기판인 PET에 증착되었다. $TiO_2$ 버퍼층을 도입함으로써 ITZO/$TiO_2$ 박막은 비정질 구조를 보여 주었고, 그것들의 비저항은 버퍼층의 두께가 증가할수록 감소함을 관찰하였다. 특히 기계적 특징은 $TiO_2$ 버퍼층을 5nm 증착하였을 경우에 bending test와 광학 현미경의 crack정도를 관찰함으로써 향상되었음을 확인할 수 있었다. 투과율에 있어서 단일 ITZO 박막과 버퍼층을 5nm 도입한 박막은 가시광선에서 약 75%의 투과율을 가짐을 알 수 있었다.

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Development of Polyclonal Antibodies to Abdominal and Subcutaneous Adipocyte for Reducing Body Fat of Rat (흰쥐 체지방 감소를 위한 지방부위별 특이 다클론 항체 개발 연구)

  • Choi, Chang-Weon;Park, Dong-Woo;Jo, Ik-Hwan;Oh, Young-Kyoon;Chang, Sun-Sik;Choi, Nag-Jin;Kam, Dong-Keun;Baek, Kyoung-Hoon
    • Journal of agriculture & life science
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    • v.46 no.5
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    • pp.47-55
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    • 2012
  • Polyclonal antisera against regional (abdominal and subcutaneous) fats were developed to reduce body fat in rats. Isolation and culture of abdominal and subcutaneous adipocytes of rats were performed for analyzing lactate dehydrogenase (LDH) concentration. At the level of 1:1,000 dilution, little antibody reactivity appeared in non-immunized serum whereas both of antisera against abdominal (AAb) and subcutaneous adipocyte plasma membrane proteins (SAb) had relatively strong reactivity till the level of 1:128,000 dilutions. Compared with regional fats, extremely low reactivities of AAb and SAb were detected with PMP of the organs (p<0.001). Both AAb and SAb were most strongly reacted with each adipocyte plasma memebrane proteins and showed statistically (p<0.01) higher cross-reactivities compared with non-immunized serum based on LDH analysis. In conclusion, these results may indicate that the present polyclonal antibodies against regional inedible adipocyte plasma membrane proteins are well developed and have safety in cross-reactivities with body organs.

Effect of Correction to Muscle Imbalance in Lower Limbs according to Reduction of Weight Bearing Methods of Four Point of Horizontal Shaft (횡축 4정점 체중부하 감소기법 이용한 하지 근력불균형 개선에 미치는 효과)

  • Kang, S.R.;Kim, U.R.;Jeong, H.C.;Kwon, T.K.
    • Journal of rehabilitation welfare engineering & assistive technology
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    • v.7 no.2
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    • pp.101-107
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    • 2013
  • In this paper, we were to investigate effect of correction to muscle imbalance in lower limbs according to reduction of weight bearing methods of four point of horizontal shaft using two-belt treadmill. Participants were divided to two group according to each ten peoples who have difference of muscle function in left and right legs over 20%. Experiment progressed forty minutes a day three days a week, total four weeks and we estimated the maximal peak torque and average power for testing joint torque in hip, knee and ankle. The results showed that the correction effect of muscle imbalance to the maximal muscle strength was the most effective in hip joint. Also in knee joint, correction effect of muscular reaction was the most effective too. We thought that reduction of weight bearing methods could be positive effect to correct muscle imbalance in lower limbs.

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Cardiovascular Responses over the Time Course during Muscle Group III Stimulation in Prehypertensive Individuals (고혈압 전단계자들에 대한 골격근 Group III 자극 시 시간에 따른 심혈관 반응)

  • Park, Won-Il;Park, Si-Young;Choi, Hyun-Min;Lee, Joon-Hee;Jeon, Jong-Mok;Kim, Jong-Kyung;Shim, Jae-Kun;Nho, Ho-Sung
    • Journal of Life Science
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    • v.19 no.11
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    • pp.1568-1574
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    • 2009
  • The purpose of this study was to investigate whether group III muscle afferents play an important role eliciting abnormal blood pressure response mediated during passive muscle stretch in prehypertensive individuals. Eleven middle-aged prehypertensive men (average BP 133/80 mmHg) and nine middle-aged normotensive men (average BP 119/74 mmHg) participated in this study. After 1 min rest baseline data collection, the subject's foot was flexed (dorsiflexion) by an automated cybex for one minute. Systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial blood pressure (MAP), heart rate, stroke volume, cardiac output, and total peripheral resistance were continuously measured on a beat-by-beat basis from a finger via a Finapres device for 1 minute. To evaluate the role of mechanoreflex, a component of exercise pressor reflex, SBP, DBP, and MAP responses over the course of time were examined. The results showed that the pressor response mediated by the muscle mechanoreflex was faster in prehypertensive individuals compared to the normotensive individuals. The substantial pressor response was observed within mean 20 sec of the onset of passive stretch in prehypertension, while mean 45 sec in normotension (p<0.05). It is concluded that excessive pressor response produced during exercise in prehypertension may be due to the dysfunction of the mechano-receptors.

Preparation of Electroless Copper Plated Activated Carbon Fiber Catalyst and Reactive Evaluation of NO Removal (무전해 도금법으로 제조된 구리 함유 활성탄소섬유 촉매의 제조와 NO 제거 반응성 평가)

  • Yoon, Hee-Seung;Oh, Jong Hyun;Lee, Hyung Keun;Jeon, Jong-Ki;Ryu, Seung Kon
    • Korean Chemical Engineering Research
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    • v.46 no.5
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    • pp.863-867
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    • 2008
  • Pitch based activated carbon fiber(ACF) was prepared from reformed naphtha cracking bottom oil(NCB oil) by melt spinning. The fibers obtained were stabilized, carbonized, and then steam activated. The ACF was sensitized with Pd-Sn catalytic nuclei via a single-step activation approach. This sensitized ACF was used as precursors for obtaining copper plated ACFs via electroless plating. ACFs uniformly decorated with metal particles were obtained with reduced copper plating in the reaction solution. Effects of the amount of copper on characteristics of ACF/Cu catalysts were investigated through BET surface area, X-ray diffraction, scanning emission microscopy, and ICP. The amount of copper increased with plating time, but the surface area as well as the pore volume decreased. NO conversion increased with reaction temperature. NO conversion decreased with increasing the amount of copper, which is seemed to be due to the reduction of surface area as well as the dispersion of copper.

Immuno-Modulatory Activity of the Crude Polysaccharide from Wild Ginseng Adventitious Root (산삼 배양근에서 분리한 다당의 면역자극 활성에 미치는 효과)

  • Nam, Sohyun;Rhee, Young Kyoung;Hong, Hee-Do;Lee, Young-Chul;Kim, Young-Chan;Shin, Kwang-Soon;Cho, Chang-Won
    • The Korean Journal of Food And Nutrition
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    • v.25 no.4
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    • pp.755-761
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    • 2012
  • In this study, we examined immuno-modulatory activities of crude polysaccharides from wild ginseng adventitious roots (WGAR). The crude polysaccharide (WGAR-CP) was isolated from WGAR by hot water extraction, ethanol precipitation, and dialysis. The major constituents in WGAR-CP were neutral sugar (64.77%), and uronic acid (34.32%). WGAR-CP demonstrated anti-complementary activity dose-dependently. The immuno-modulatory effects of WGAR-CP were also analyzed by measuring nitric oxide and cytokines in the supernatants of mouse peritoneal macrophages. Mouse peritoneal macrophages stimulated with WGAR-CP produced nitric oxide and various cytokines such as interleukin (IL)-6 and IL-12 in a dose-dependent manner. In conclusion, WGAR-CP may have immuno-modulatory activities by activating a complementary system and macrophages, which produces cytokines.

Effect of GABA on the Contractility of Isolated Canine Trachealis Muscle (개의 기관근 수축성에 미치는 GABA의 효과)

  • Koo, Cheol-Hoe;Kwon, Oh-Chul;Choi, Eun-Mee;Lee, Kwang-Youn;Kim, Won-Joon
    • Journal of Yeungnam Medical Science
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    • v.11 no.2
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    • pp.314-322
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    • 1994
  • This study aimed to investigate the existence of GABA receptor and the mechanisms of action of GABA and diazepam on the trachealis muscle isolated from dog. Horizontal muscle strips of $2mm{\times}15mm$ were prepared from canine trachea, and isometric myography in isolated muscle chamber bubbled with 95/5%-$O_2/CO_2$at $36^{\circ}C$, at the pH of 7.4 was performed. Muscle strips contracted responding to the electrical field stimulation (ESP) by 2~20 Hz, 20 msec, monophasic square wave of 60 VDC GABA and diazepam suppressed the EFS-induced contractions to the similar extent, significantly. (p<0.05) Bicuculline, a $GABA_A$ receptor antagonist blocked both GABA- and diazepam- inhibitions; but DAVA, a $GABA_B$ receptor antagonist did not affect either of them. These results suggest that in the canine trachealis muscle, there may be only $GABA_A$ receptor, and GABA and diazepam inhibit the contractility via $GABA_A$A receptor.

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