• Journal of Chest Surgery
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• v.40 no.1 s.270
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• pp.69-73
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• 2007

The mortality rate of the invasive pulmonary aspergillosis to be able to developed during chemotherapy induced myleosuppressionin is high in hematologic malignancy patients despite antifungal treatment. Effective antifungal treatment combined with operation can decrease the mortaligy rate of the invasive pulmonary aspergillosis. Recently, we experienced the successful management of the two cases of invasive pulmonary aspergillosis in acute lymphoblastic leukemia through effective antifungal treatment and surgical resection. We report this cases with review of literature.

• The Journal of Natural Sciences
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• v.11 no.1
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• pp.159-164
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• 1999

The study was investigated to the effect of antimicrobial finishing of towel treated by organic antimicrobial agent. It was measured for the optimal condition such as treated time, treated concentration and temperature. After amtimicrobial treatment, mechanical and fastness properties, anti-laundering property were measured.The antimicrobial activity of samples was analyzed quantitatively by masureing the number of colonies of Staphylococcus aureus using the shake flask method. Towel samples treated with the optimal condition such as treated time of 10 minute, and treated temperature of $30^{\circ}C$, concentration of organic antimicrobial agent of 3.5% were shown a high reduction rate in the number of colonies grown and clear zones of inhibition.The effect of reduction rate for laundering until the number of 20 times was shown high reduction rate of over 80%. And the mechanical properties of samples treated with organic antimicrobial agent were not changed approximately.

• Korean journal of applied entomology
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• v.61 no.1
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• pp.155-163
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• 2022

The application of fungicides is indispensable to global food security, and their use has increased in recent times. Fungicides, directly or indirectly, have impacted insects, leading to genetic and molecular-level changes. Various detoxification mechanisms allow insects to eliminate reactive oxygen species (ROS) toxicity induced by agrochemicals including fungicides. In the present study, we analyzed the mRNA expression levels of detoxifying enzymes in Tenebrio molitor larvae following exposure to non-lethal doses (0.2, 2, and 20 ㎍/µL) of a fungicide captan. Transcripts of peroxidases (POXs), catalases (CATs), superoxide dismutases (SODs), and glutathione-s-transferases (GSTs) were screened from the T. molitor transcriptome database. RT-qPCR analysis showed that TmPOX5 mRNA increased significantly 24 h post-captan exposure. A similar increase was noticed for TmSOD4 mRNA 3 h post-captan exposure. Moreover, the expression of TmCAT2 mRNA increased significantly 24 h post-treatment with 2 ㎍/µL captan. TmGST1 and TmGST3 mRNA expression also increased noticeably after captan exposure. Taken together, these results suggest that TmPOX5 and TmSOD4 mRNA can be used as biomarkers or xenobiotics sensors for captan exposure in T. molitor, while other detoxifying enzymes showed differential expression.

• Proceedings of the Korean Society of Dyers and Finishers Conference
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• 2012.03a
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• pp.89-89
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• 2012

선행 연구에서는 m-Aramid와 p-Aramid의 Ring 방적사/Core 방적사 조건에 따른 방적사 물성에 대해서 연구하였는데, Ring 방적사의 혼용율, 스핀들 속도에 따른 물성 변화, Core 방적사의 공정특성에 따른 방적성, 피복성에 대해 연구를 하였다. 그 결과 Ring 방적사의 경우 m-Aramid의 혼용율이 증가할수록 사 강도는 증가하는 경향을 확인할 수 있었고, 스핀들 속도가 증가함에 따라서 불균제도 및 사결점이 다소 증가하였다. Core 방적사의 경우 Core에 p-Aramid를 사용했을 때 방적성과 피복성은 양호 하였지만, 강한 p-Aramid에 의해 톱 롤러코트의 마모가 되는 경향을 볼 수 있었다. 본 연구에서는 Ring 방적사/Core 방적사에 대해 좀더 구체적인 제조공정조건에 의한 물성 변화를 알아보았고, 좀더 다양한 섬유소재를 적용해서 제조하였다. Ring 방적사의 경우 p-Aramid 혼용율에 따른 실험을 하였는데, m-Aramid에 대한 p-Aramid의 혼용율을 0%, 5%, 10%, 20% 로 하여 Ne30을 제조하였으며, Core 방적사는 Core를 p-Aramid 200D로 하고 Sheath를 Cotton으로 하여 Core 공급속도비 (1.06, 1.10, 1.14), 연계수(T/M, 3.8, 4.0, 4.2), Sheath/Core 혼섬율(70/30, 60/40, 50/50)에 따라 제조하였다. 추가로 Core 방적사는 Sheath에 Cotton 대신 FR-Rayon과 선염 Cotton을 사용하여 각각 Sheath/Core 혼섬율 70/30의 비율로 방적사를 제조하여 다양한 소재에 따른 방적사의 물성을 측정하였다. 제조된 시험 원사들의 측정 물성은 번수(Ne), 균제도(U%), 사결점(IPI), 강력(cN), 신도(%), 비강도(cN/Tex) 등이며, 편직을 통해 편성물의 외관을 확인하였다. Ring 방적사의 경우 p-Aramid의 혼용율이 증가할수록 강도는 완만하게 증가한 반면, 신도는 급격하게 감소하였다. Cotton Core 방적사의 경우는 공급속도비가 높아질수록 균제도가 높아지는 것을 볼수 있었고, Core 공급속도비가 높아질수록 외관상 피복도는 높아진 것을 볼 수 있었다. 이렇게 연구된 Aramid 소재를 이용한 방적사 제조 공정조건변화에 따른 물성 및 피복도 결과는 기존 방적업체에서 Aramid를 이용한 방적사 제조시에 공정조건을 확보하는데 도움이 될 것이라 생각되며, 방적사 시제품 생산시에 발생할 수 있는 시행착오를 줄임으로써 시제품 제조를 위한 생산비용의 Loss를 절감할 수 있을 것으로 예상된다.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.19 no.2
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• pp.13-22
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• 2005

This research aimed to generate two points of daylighting application as follows: 1) providing daylight performance data with a variety of glazing materials for a large window and 2) designing and evaluating an experimental type of differentiated window. For this purpose, we compared the daylight and distribution performance of new defined type of window configuration to the conventional window counterpart with a variety of glazing materials. The comparison was made for a deep, south-facing perimeter zone with large window, without any interior obstruction. The conventional window is the base single homogeneous glass pane, where as the differentiated window uses of two different glazings; an upper daylight glazing with high visible transmission and lower view window with lower transmittal glass. The daylight performance data was translated into a ratio between outdoor illuminance and the interiors. The simulated analysis of the conventional window indicates that the interior light levels have been changed proportionally dependent on the transmittance of the applied glass. The comparison of daylight distribution analysis showed that the differentiated window has lots of photometric advantage by the optical function of upper daylight window. In particular, the contribution of higher daylight window into deep rear space must be stressed for daylighting application.

• Polymer(Korea)
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• v.33 no.4
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• pp.389-395
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• 2009

To develop the carrier of hydrophobic antifungal agents based on low molecular weight water-soluble chitosan (LMWSC), LMWSC was chemically modified with deoxycholic acid (DA) which is one of the bile acid as a hydrophobic group. The nanoparticles (WSCDA) using DA conjugated LMWSC were characterized using dynamic light scattering (DLS) and transmittance electron microscope (TEM). The particle size of WSCDA ranged from 250 to 350 nm and increased with the number of DA substitution. The loaded itraconazole as an antifungal agent WSCDA nanoparticles (WSCDA-ITCN) were prepared by solvent evaporation method. The drug content and the loading efficiency were investigated approximately $9{\sim}10%$ and $61{\sim}68%$ by UV spectrophotometer, respectively. The release of drug from nanoparticles was slow and showed sustained release characteristics. Based on the results of release study that the higher DA contents in WSCDA, the slower the releasing rate, the WSCDA-ITCN could be used as an excellent antifungal agent.

• Korean Journal of Clinical Laboratory Science
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• v.54 no.2
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• pp.133-141
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• 2022

Candida is one of the most common causes of bloodstream infections and a leading cause of morbidity and mortality among hospitalized patients. The purpose of this study was to provide important information for formulating empirical treatment plans for candidemia by investigating the antifungal resistance rate of Candida. Among the Candida strains (973 cases) isolated from blood culture tests at the S hospital in 2009~2018, 4.7% (N=44) comprising the Candida spp. (932 strains) showed resistance to fluconazole. The resistant strains included C. albicans, C. parapsilosis, C. tropicalis, and C. glabrata. In addition Candida spp. (947 strains) showed resistance to amphotericin B (N=6, 0.6%), flucytosine (N=23, 2.4%) and voriconazole (N=24, 3.1%). C. albicans was resistant to fluconazole (N=23, 6.9%) and voriconazole (N=21, 6.0%), The statistical analysis showed that C. albicans and non-albicans Candida species were resistant to fluconazole (P=0.039) and voriconazole (P<0.001). A monitoring system to understand the rate of candidiasis infections in a hospital setting is required. It is also important to make the right choice of the antifungal agent based on drug susceptibility patterns. Therefore, an infection surveillance policy that tracks Candida resistance through regular antifungal susceptibility tests is necessary.

• Bulletin of Food Technology
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• v.11 no.4
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• pp.70-80
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• 1998

해양자원으로부터 상업적인 가치를 지니는 천연물질들을 획득하는 것은 일본의 수산업에 있어서 매우 중요하다. 일본에서는 해양자원의 부산물을 이용하여 다양하고 많은 상업적인 제품들을 성공적으로 개발하고 있다. 키틴, 키토산, 어유, 액정(liquid crystal), 프로타민(protamine, 식품에 향균제로 사용되며 물고기의 고환으로부터 얻음), 어류양식장에서 사용하는 성장호르몬, 해양생물로부터 추출하는 몇가지 의약품 등이 대표적인 예이다.

• Proceedings of the Korean Fiber Society Conference
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• 1998.04a
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• pp.209-213
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• 1998

방적공정중에서 섬유속의 선밀도 감소와 평행화도 증가를 위해서 행해지는 드래프트 공정은 섬유속의 선밀도를 감소시킴과 동시에 불균제도를 증가시키게 된다. 실제의 생산설비는 드래프트로 인해 발생되는 불균제를 최소화하기 위해 여러 가지 다양한 기구를 사용한다. 드래프트 공정에서의 불균제도 증가는 드래프트 공정의 조건에 따라 그 정도를 달리하게 되는데, 최적의 공정조건은 공급되는 섬유속의 특성에 따라 변화시켜주어야 한다.(중략)

• Proceedings of the Korean Aquaculture Society Conference
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• 2004.05a
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• pp.128-129
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• 2004