• Title/Summary/Keyword: 과다형성

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미취학 아동에 있어 신체발달, 손목 골밀도 및 영양섭취와의 상관성

  • 나현주;명금희;최미경;김애정
    • Proceedings of the KSCN Conference
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    • 2003.11a
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    • pp.1051-1052
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    • 2003
  • 미취학 아동기는 생후 1년 동안의 급격한 성장 이후로부터 학령기가 되기 전까지 성장이 완만해지는 시기이다. 이 시기의 아동들은 혼자 먹는 행동을 익히게 되고 식품에 대한 기호가 형성되는 등 식생활에서도 뚜렷한 개인특성을 갖게되며 이 시기에 형성된 식습관은 성인까지 이어지게 된다. 이 시기에 영양부족에 따른 신체발달의 지연이나 영양과잉에 따른 비만과 같은 과다한 신체발달의 문제점이 지적되고 있어 올바른 식습관 형성은 신체발달과 밀접한 관련성이 있는 것으로 보여진다. 우리나라는 취약한 칼슘섭취 부족에 따라 골격건강에 대한 관심이 크게 증가하고 있는데, 모든 질환이 그러하듯이 골격질환도 치료보다는 예방적인 관리가 다양한 측면에서 효율적이다. 따라서 골격건강과 최적의 신체발달을 위한 식사인자는 매우 중요하며, 일생의 성장시기에 따라 서로 다른 인자들이 관여할 것으로 생각된다. 이에 본 연구에서는 성장이 이루어지면서 식품선택의 독립성이 확립되는 미취학 아동에 있어 신체와 골격 발달에 관련성이 있는 영양섭취 요인을 찾아봄으로써 골격과 신체 발달을 위한 올바른 식습관 형성에 필요한 기초자료를 제시하고자 하였다. 이에 46~84개월의 미취학 어린이 총 62명(남자 37명, 여자 25명)을 대상으로 어머니에 의한 설문조사를 실시하고 대상자의 신체계측(InBody, Biospace)과 손목의 골밀도(DEXA, Medilink)를 측정하였다. 설문지는 어린이와 부모의 일반사항, 어린이의 건강상태, 식습관 및 활동조사표와 24시간 회상법에 의한 식사조사표로 구성하였다. 식사섭취조사 결과는 CAN-Pro를 이용하여 영양소 섭취량을 분석하였으며, 모든 연구결과는 SAS program을 이용하여 통계 분석하였다. 연구결과를 요약하면 다음과 같다. 남녀 어린이의 평균 월령은 62.43$\pm$7.26 개월과 62.12$\pm$8.85개월이었다. 출생시 신장과 체중은 남자 어린이가 50.92$\pm$2.14 cm와 3.36$\pm$0.42kg, 여자 어린이는 각각 50.29$\pm$1.36cm와 3.32$\pm$0.39kg이었다. 현재 신장과 체중은 남자 111.65$\pm$5.44 cm와 19.60$\pm$3.52kg, 여자 109.04$\pm$5.04 cm와 18.67$\pm$2.81kg이었으며, 비만지수는 남녀 각각 -2.13$\pm$9.09%와 0.22$\pm$10.49%였다. 손목의 골밀도는 남녀 어린이 각각 0.25$\pm$0.04g/cm, 0.24$\pm$0.03g/$\textrm{cm}^2$이었다. 에너지 섭취량은 남녀 어린이 각각 영양권장량의 66.43$\pm$18.58%와 70.46$\pm$20.31% 수준이었으며, 남녀 어린이 모두 단백질(124.97$\pm$37.55%, 131.24$\pm$45.49%), 비타민B$_{6}$ (152.48$\pm$47.01%, 152.95$\pm$61.77%), 엽산(106.87$\pm$40.44%, 104.52$\pm$50.16%), 비타민 E (121.04$\pm$52.79%, 113.48$\pm$75.78%)를 제외한 영양소 섭취량이 권장량에 미달되는 섭취수준을 보였다. 특히 성장기에 중요한 칼슘도 남녀 어린이 각각 권장량의 62.21$\pm$39.46%와 70.07$\pm$34.52%로 낮게 섭취하고 있었다. 모든 영양소 섭취량은 남녀 어린이간에 유의한 차이가 없었다. 신체계측치와 영양섭취와의 관계에서 체중, 체수분량, 제지방량은 각각 동물성 철 섭취량과 유의한 부의 상관관계를 보였다(p<0.05, p<0.01, p<0.01). 골밀도와 영양섭취와의 관계에서 손목 골밀도는 식물성 칼슘 섭취량과 유의한 정의 상관관계를 보였고(p<0.05), 특히 위쪽 손목 골밀도는 동물성 단백질, 동물성 철 섭취량과 각각 유의한 부의 상관을 보였다(p<0.05, p<0.05). 이상의 연구결과를 종합할 때 성장이 진행되고 있는 미취학 아동에 있어 신체상태와 골밀도는 동물성 단백질, 식물성 칼슘, 동물성 철 섭취량과 상관성이 있는 것으로 나타남으로써 앞으로 이들 영양소의 섭취가 신체와 골격 성장에 어떠한 영향을 미치는가에 대한 보다 세부적인 연구가 이루어져야 할 것으로 생각된다.

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River Basin based Region Reconstruction and it's Regulation Analysis: A Case of Gangwon Province (하천 유역권에 의한 권역구분과 권역별 규제지역 분석 - 강원도 지역을 대상으로 -)

  • Kim, Chang-Hwan;Bae, Sun-Hak
    • Journal of the Korean Association of Geographic Information Studies
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    • v.9 no.1
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    • pp.20-33
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    • 2006
  • Changing of industry structure and development of traffic and telecommunications requires a change of the knowledge about the space where the human beings reside. Step by step the world is being divided into specified utility blocks. Today there is a limit that only one local government can compete with another region in the world. This study provides decision support tools with the use of GIS on the regional level for regions competition. GIS establishes regions and analyzes their geographic environment data, which will help in local-government problem solving and provide framework data for similar regions to become the community. The wide-area GIS application can present an objective and rational basis for regulation of inefficient investments and excessive competition between adjacent regions. The study area is Gangwon-do. Considering specific features of Gangwon-do which preserved high-quality environment resources, river basins were taken as a basis among natural regional elements. The main object of analysis conducted were the facts relevant to environmental regulation. The Gangwon-do consists of three regions in this study: Yongdong region, North-Hangang region and South-Hangang region. The analysis of each region regulation cases showed the following: in Youngdong region the forests regulation rate is high, in North-Hangang region the military installations protection sector's rate as well as regulation rate for water resources protection is relatively high, in South-Hangang region the forest and water resources regulation rate is high. The percentage of forests and water regulation rate appeared to be rather high in Gangwon-do, which means that the value of forest and water resources there is very high.

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Distributed Mobility Management Scheme in LTE/SAE Networks (LTE/SAE 네트워크에서 분산 이동성 관리 기법)

  • Kim, Yong-Hwan;Han, Youn-Hee;Kim, Min;Park, Seok Yong;Moon, Sang Jun;Lee, Jin Ho;Choi, Dae Kyu
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.38B no.11
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    • pp.879-894
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    • 2013
  • Recently, due to a explosive growth in the mobile Internet traffic, the problem of excessive data traffic handling on core network and thus scalability problem have been magnified in 3GPP LTE/SAE networks. Current LTE/SAE network based on the central P-GW (PDN Gateway) used as mobility anchor cannot deal with such demand for exponentially increasing mobile Internet traffic. In this paper, we propose a new LTE/SAE network architecture supporting distributed P-GWs and corresponding distributed mobility management to solve these problems. For this, in addition to the deployment of such distributed P-GWs, we propose a dynamic and distributed mobility management by distributing MMEs (Mobility Management Entities) which dynamically manages the location information of a UE's PDN connection, and also propose a handover procedure of such PDN connections by using the proposed distributed P-GWs and MMEs. The performance of the proposed dynamic and distributed LTE/SAE network system is compared with the current LTE/SAE network system in terms of handover latency and network throughput.

Effect of the Ethanol Extract from Lavandula vera on ${\alpha}$-MSH Induced Melanogenesis (라벤더 에탄올 추출물이 ${\alpha}$-MSH 유도 멜라닌 생성에 미치는 효과)

  • Kim, Ho-Min;Jang, Yeong-Mi;Han, Kyu-Soo;Moon, Dea-Won;Mun, Yeun-Ja;Woo, Won-Hong
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.22 no.6
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    • pp.1444-1448
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    • 2008
  • Down-regulation of melanin synthesis is required for recovery of pigmentary disorders and it is well known that ${\alpha}$-MSH induced melanin synthesis and dendrite outgrowth on melanocytes. This study was conducted to evaluate the depigmenting properties of ethanol extract from a Lavandula vera. The ethanol extract from Lavandula vera inhibited melanin contents and tyrosinase activity in a dose-dependent manner, compared with untreated group. Treatment of the ethanol extract of Lavandula vera effectively suppressed the ${\alpha}$-MSH-stimulated melanin formation, tyrosinase activity and dendrite outgrowth. Moreover, the ${\alpha}$-MSH-induced mRNA expression of tyrosinase was significantly attenuated by Lavandula vera treatment. These results suggest that Lavandula vera exerts its depigmenting effects through the suppression of tyrosinase and cytoplasmic dendricity. And it may be a potent depigmetation agent in hyperpigmentation condition.

Field Application of a Precast Concrete-panel Retaining Wall Adhered to In-situ Ground (원지반 부착식 판넬옹벽의 현장 적용성 평가)

  • Min, Kyoung-Nam;Lee, Jae-Won;Lee, Jung-Gwan;Kang, In-Kyu;Ahn, Tae-Bong
    • The Journal of Engineering Geology
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    • v.26 no.1
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    • pp.51-61
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    • 2016
  • New building methods are needed to aid increased inner-city redevelopment and industrial construction. A particular area of improvement is the efficient use of cut slopes, with the minimization of associated problems. A retaining wall of precast panels can resist the horizontal earth pressure by increasing the shear strength of the ground and reinforcing it through contact with the panels. Precast panels allow quick construction and avoid the problem of concrete deterioration. Other problems to be solved include the digging of borrow pits, the disposal of material cut from the slope, and degradation of the landscape caused by the exposed concrete retaining wall.This study suggest the methods of improvement of an existing precast panel wall system by changing the appearance of the panels to that of natural rock and improving the process of adhering the panel to a vertical slope. The panels were tested in the laboratory and in the field. The laboratory test verified their specific strength and behavior, and the field test assessed the panels' ground adherence at a vertical cutting. Reinforcement of the cutting slope was also measured and compared with the results of 3D numerical analysis. The results of laboratory test, identified that the shear bar increase the punching resistance of panel. And as a results of test construction, identified the construct ability and field applicability of the panel wall system adhered to in-situ ground. In addition to that, extended measurement and numerical analysis, identified the long-term stability of panel wall system adhered to in-situ ground.

Mode of Occurrences and Depositional Conditions of Arsenopyrite from the Yeonhwa 1 Mine, Korea (연화 제1광산에서의 유비철석의 산상과 배태 조건)

  • Lee, Young-Up;Chung, Jae-Il
    • Journal of the Mineralogical Society of Korea
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    • v.16 no.1
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    • pp.1-17
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    • 2003
  • The chemical composition of the arsenopyrite Ib adjoining“triple mutual contact”arsenopyrite + pyrite + hexagonal pyrrhotite may serve as a useful geothermometer in Stage II. In this study it corresponds to temperature T=33$0^{\circ}C$ and f( $S_2$)=10$^{-9.5}$ atm. And the pyrite-hexagonal pyrrhotite buffer curve indicates the probable range of the two variables; T= 315∼345$^{\circ}C$, and f( $S_2$)=10$^{-1}$0.5/∼10$^{-9}$ atm. The present antimony-bearing arsenopyrite (arsenopyrite Ic) is characterized by relatively high content of antimony, ranging from 4.95 to 8.91 percent Sb by weight and excess of iron and deficiency of anions are evident. Such a high antimonian arsenopyrite has never been known within single grain. But being the high content of antimony as in the arsenopyrite Ic, it does not serve as a geothermometer. The results of microprobe analyses for four pairs of asenopyrite and sphalerite in Stage III indicate the temperature range from 310 to 34$0^{\circ}C$, and sulphur fugacity range from 10$^{-10}$ ∼10$^{-9}$ atm. These values seem to correspond with those inferred from the Fe-As-S system.m..

Molecular Cloning and Nucleotide Sequence Analysis of pyrB Gene Encoding Aspartate Transcarbamylase from Psychrophilic Sporosarcina psychrophilia (저온성균 Sporosarcina psychrophilia로부터 Aspartate Transcarbamylase 유전자의 클로닝 및 염기서열 분석)

  • 성혜리;안원근;김사열
    • Microbiology and Biotechnology Letters
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    • v.30 no.4
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    • pp.312-319
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    • 2002
  • The Sporosarcina psychrophilia pyrB gene, which encodes aspartate transcarbamylase (ATcase), was cloned on Sau3AI restriction endonuclease fragment inserted into pUC19 plasmid vector, S. psychrophilia pyrB gene was expressed in Escherichia coli pyrB mutant for the complementation test. The sequence of 2,606 nucleotides including putative pyrB gene was determined. The region contained one full open reading frame (ORf) and two partial ORFs. The deduced amino acid sequence of the second ORF showed 59% identity with that of Bacillus caldolyticus ATCase. The first and third partial ORFs were closely related to the uracil permease (pyrP) and dihydroorotase (pyrC), respectively. Besides, potential terminator, antiterminator, and anti-antiterminator structures were found in the intergenic region between pyrP and pyrB. These results suggested that S. psychrophilia pyrimidine nucleotide biosynthesis genes are clustered as well as other Bacillus sp. Over-expressed product of pyrB encoding ATCase was purified and analyzed by the SDS-PAGE. The purified PyrB protein turned out to be molecular mass of 27 kDa and showed ATCase activity.

Anticancer Activity of Methyl Gallate in RC-58T/h/SA#4 Primary Human Prostate Cancer Cells (인체 전립선 암세포에서 Methyl Gallate의 항암효과)

  • Kwon, Soon Jae;Lee, Ju Hye;Kim, Jae Yong;Moon, Kwang Deog;Yee, Sung Tae;Seo, Kwon Il
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.43 no.3
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    • pp.367-373
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    • 2014
  • In this study, we investigated the anticancer activity of methyl gallate (MG), which is the major biologically active component of Galla Rhois, in RC-58T/h/SA#4 human prostate cancer cells. MG inhibited cell proliferation in a dose-dependent manner. Cell death induced by MG increased the population of cells in sub-G1 phase, formation of apoptotic bodies, nuclear condensation, and DNA fragmentation. Apoptosis induced by MG was associated with activation of initiator caspases-8 and -9 as well as effector caspase-3. Endocrine disruptors such as dioxin and bisphenol A increased growth of RC-58T/h/SA#4 cells in charcoal-treated FBS (cFBS) medium. Cell proliferation was highest upon treatment with 1 nM and $0.1{\mu}M$ dioxin and bisphenol A, respectively. MG also dose-dependently inhibited cell proliferation in RC-58T/h/SA#4 cells treated with endocrine disruptors. These results indicate that MG exerts anticancer effects on RC-58T/h/SA#4 primary human prostate cancer cells.

Predictors of Positive Changes in Children with Divorced Parents: Focused on Moderating Effects of Family Incomes (이혼 가정 자녀의 긍정적 변화에 영향을 미치는 변인 분석: 가구 소득의 조절효과)

  • Choi, Hyo-Sik
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.6
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    • pp.465-475
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    • 2018
  • The purpose of this study was to explore predictors of positive changes in children with divorced parents and to demonstrate the structural path among the perceived experience of social discrimination, parenting difficulties, parent-child communication, and internet use of children that related to positive changes based on family incomes. The subjects for this study were 1,114 single parents from divorced families sourced from a study on the status of single-parent families in 2015. The results of this study by using the structural equation model of the moderating effect verification with family incomes and multi group analysis are as follows. First, single-parent's perceived experience of social discrimination turned had a significant positive effect on parenting difficulties( =.354) and children's internet use ( =.234). Single-parent's perceived parenting difficulties also had a significant positive effect on children's internet use ( =.440) but a significant negative effect on both parent-child communication( =.192) and positive changes of children( =.218). Interestingly, internet use of children demonstrated a significant negative effect on their positive changes. Second, parent-child communication, parenting difficulties, and children's internet use had a negative mediating effect with the relationship where single-parent's perceived experience of social discrimination had an effect on positive changes of children( =.167). Second, between the family groups based on family incomes, there was no statistically significant difference in the structural relationship. Based on these results, this study presented a practical proposal to help single parents not experience social discrimination and to help decrease the internet use of children to improve positive changes.

Development of High Performance Curing Agent and Effective Dispersion Method of Nanomaterials (고성능 피막양생제 개발 및 나노물질의 분산방안 평가)

  • Son, Ho-Jung;Yoo, Byung-Hyun;Lee, Dong-Gyu
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.12
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    • pp.230-236
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    • 2019
  • Recently, issues related to the quality of concrete have continuously resulted in surface quality problems, such as the exfoliation of concrete surfaces due to the cost reduction of cement and poor quality fine aggregate, scaling of surfaces caused by laitance, and plastic shrinkage cracks. Prompted by social issues, the application of a photo catalyst to road structures is being attempted to solve the environmental problems caused by fine dust and automobile exhaust. In this study, chemical admixtures were developed to improve the surface quality of concrete and to apply and distribute titanium dioxide in nanoscale sizes to provide basic data for the development of a photocatalyst-curing agent. As a result of the experiment, silicon and silane were reviewed as a raw material as a curing agent to develop a high performance curing agent with better film performance than conventional curing agents because they could form a film quickly on a fresh concrete surface. The distributed stability of the ultrasonic disperser showed the best performance through an outdoor test for four weeks to review the dispersion measures for the application of nanomaterials.