• Korean Journal of Psychosomatic Medicine
• /
• v.27 no.1
• /
• pp.42-49
• /
• 2019

Objectives : Living donor liver transplantation (LDLT) is a life-saving therapy for patients with terminal liver disease. Many studies have focused on recipients rather than donors. The aim of this study was to assess the emotional status and personality characteristics of LDLT donors. Methods : We evaluated 218 subjects (126 male, 92 female) who visited Daegu Catholic University Medical Center from August 2012 to July 2018. A retrospective review of their preoperative psychological evaluation was done. We investigated epidemiological data and the Minnesota Multiphasic Personality Inventory-2 questionnaire. Subanalysis was done depending on whether subjects actually underwent surgery, relationship with the recipient, and their gender. Results : Mean age of subjects was $32.19{\pm}10.91years$. 187 subjects received LDLT surgery (actual donors) while 31 subjects didn't (potential donors). Donor-recipient relationship included husband-wife, parent-children, brother-sister etc. Subjects had statistical significance on validity scale L, F, K and all clinical scales compared to the control group. Potential donors had significant difference in F(b), F(p), K, S, Pa, AGGR, PSYC, DISC and NEGE scales compared to actual donors. F, D and NEGE scales were found to be predictive for actual donation. Subanalysis on donor-recipient relationship and gender also showed significant difference in certain scales. Conclusions : Under-reporting of psychological problems should be considered when evaluating living-liver donors. Information about the donor's overall psychosocial background, mental status and donation process should also be acquired.

• Journal of Chest Surgery
• /
• v.39 no.3 s.260
• /
• pp.226-229
• /
• 2006

Recently, heart transplantation has been accepted as a standard treatment for infant and children with end-stage cardiomyopathy or complex congenital heart disease. Due to the shortage of donors, size-mismatched cardiac transplantation is common. After size-mismatched transplantation, there could be side-effects such as hypertension and hypertensive encephalopathy because of the big-heart. Donor heart is also known to do remodel as time goes by. This is a case report of a size-mismatched heart transplantation between 9-year-old boy and a 39-year-old female whose body weight is almost twice of him. In this case, classical postoperative hypertension and hypertensive encephalopathy developed but was successfully managed. The donor heart has remodeled to normal dimension during 3 years follow-up period.

• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• v.10 no.2
• /
• pp.166-172
• /
• 2007

Purpose: It has recently been reported that de novo HBV infection following liver transplantation is caused by grafts from HBcAb positive donors, and this phenomenon has been observed in one third of the liver transplant patients in our center. Therefore, we investigated the presence of HBV virus DNA in liver tissues obtained from HBcAb positive donors to determine the mechanism by which de novo HBV infection occurs. Methods: This study was conducted on 6 patients that were HBsAg negative, HBsAb positive, and HBcAb positive who were donors for liver transplantation between November 1997 and November 1998 at Asan Medical Center. We isolated DNA from a portion of liver biopsy tissues that were obtained during the operation, and then identified the surface and core region of HBV DNA using nested PCR. In addition, four children who received liver grafts from these donors were monitored to determine if they became afflicted with non-HBV related diseases while receiving prophylaxis consisting of short-term HBIG treatment and long-term treatment with an antiviral agent. Results: The surface antigen region was identified in all 6 donors and the core antigen region was observed in 4 of the 6 donors. However, no episodes of de novo HBV infection with prophylaxis were observed. Conclusion: The results of this study support the results of previous studies, which indicated that HBV infection may be the main cause of de novo HBV infection in patients that receive HBsAb positive and HBcAb positive donor grafts.

• Korean Journal of Psychosomatic Medicine
• /
• v.31 no.2
• /
• pp.43-49
• /
• 2023

In Korea, the dependence on living donations is high due to the shortage of organs available for donation compared to the number of people waiting for transplants and the number of living organ donations continues to increase. In particular, the number of living-donor transplantations is high worldwide, highlighting the importance of pre-transplant psychosocial evaluation of living kidney donors. According to previous studies, when evaluating living organ donors before transplantation, it is crucial to determine whether the donor can give informed consent and be aware of the risks after surgery. Pre-transplant evaluation tests such as ELPAT living organ donor Psychological Assessment Tool (EPAT), Live Donor Assessment Tool (LDAT), Living Donation Expectancies Questionnaire (LDEQ), Minnesota Multiphasic Personality Inventory-2 questionnaire (MMPI-2) and Temperament and Character Inventory (TCI) are conducted for donors. After reviewing the literature on these pre-transplant psychosocial assessment tools, we will also look at legal considerations for living kidney donors in Korea and suggest an effective and essential pre-transplant screening evaluation method for living kidney transplant donors.

• Proceedings of the Korea Contents Association Conference
• /
• 2015.05a
• /
• pp.149-150
• /
• 2015

병렬영상기법(parallel imaging technique)은 하나의 수신 코일을 사용하는 기존의 방식과 달리 다수의 수신코일을 이용하여 데이터를 획득하는 기법으로서 검사시간 및 공간해상도를 향상시키기 위해 사용된다. 본 논문은 간 공여자의 자기공명영상 췌담관 조영술에서 간담도 영상의 선예도 향상을 위한 병렬영상기법의 유용성을 연구하고자 하였다.

• 간의등불
• /
• s.24
• /
• pp.5-9
• /
• 2002

• KDI Journal of Economic Policy
• /
• v.9 no.1
• /
• pp.83-91
• /
• 1987

기술(技術)의 도입자(導入者)는 그 대가(代價)로서 기술공여자측(技術供與者側)의 직접비용(直接費用)뿐만 아니라 시장진출(市場進出) 기회(機會)의 상실을 보상하여 주는 간접비용(間接費用) 및 기술시장(技術市場)의 불완전(不完全)함에 따른 독점적(獨占的) 이윤(利潤)까지 지불(支拂)하여야 한다. 본고(本稿)에서는 기술도입대가(技術導入代價)에서 직접비용(直接費用), 간접비용(間接費用) 및 독점적(獨占的) 이윤(利潤)이 차지하는 비중(比重)을 기술도입업체(技術導入業體)에 대한 설문조사(設問調査)를 통하여 밝히고, 독점적(獨占的) 이윤(利潤)의 결정요인(決定要因)을 분석(分析)하였다. 실증분석(實證分析) 결과(結果)에 의하면, 첫째, 독점적(獨占的) 이윤(利潤)의 비중(比重)은 기술(技術)의 성격(性格)에 따라 큰 차이를 보이고 있기는 하나 평균적(平均的)으로 전체(全體) 기술대가(技術代價)에서 약 70% 이상(以上)을 차지하고 있고, 둘째 독점적(獨占的) 이윤(利潤)의 비중(比重)의 결정요인(決定要因)은 기술(技術)이 개발(開發)된 시점(時點)에서 이전(移轉)될 때까지의 시차(時差), 세계적(世界的)으로 동일기술(同一技術)의 잠재적(潛在的) 공여가능기업(供與可能企業)의 수(數) 및 기술(技術)이 일본(日本)으로부터 도입(導入)되었는지의 여부(與否)를 포함(包含)한다. 즉, 기술(技術)이 개발(開發)된 후 도입시기(導入時期)까지의 기간이 길수록, 기술(技術)의 잠재적(潛在的) 공여가능기업(供與可能企業)의 수(數)가 많을수록 독점적(獨占的) 이윤(利潤)의 비중(比重)은 낮아지며, 일본(日本)의 기술공여자(技術供與者)는 다른 나라의 공여자(供與者)에 비하여 보다 높은 독점적(獨占的) 이윤(利潤)을 대가(代價)에 포함시킨다.

• Journal of The Korean Radiological Technologist Association
• /
• v.28 no.1
• /
• pp.331-331
• /
• 2002

• Korean Journal of Transplantation
• /
• v.31 no.4
• /
• pp.177-181
• /
• 2017

Living donor liver transplantation (LDLT) has become an inevitable procedure due a shortage of deceased donors under the influence of religious and native cultures. The most important concern in LDLT is donor safety. This study reviewed the safety of LDLT donors from reported studies of morbidity and mortality. Many studies have reported mortality and morbidity rates ranging from 0% to 33% for healthy liver donors. Use of laparoscopic surgery on LDLT donors has advantages of reduced blood loss, lower postoperative morbidity and shorter hospital stay relative to conventional open surgery. There is a consensus that remnant liver volume (RLV), degree of steatosis, and donor age are the most important factors influencing donor safety. In LDLT, donor hepatectomy can be performed successfully with minimal and easily controlled complications. However, a large-scale prospective cohort study is needed to better understand the risk factors and accurately determine the complication rates for LDLT.

• Radiation Oncology Journal
• /
• v.17 no.2
• /
• pp.158-165
• /
• 1999

Purpose : To investigate the percentage of colonies wi1h16or more cells distribution of human skin fibroblast according to in vitro aging, and to evaluate the relationship between percentage of colonies with 10 or more cells and in vivo donor age in human skin fibroblast culture. Material and Method : C1, C2, C3a, and C3b human skin fibroblast samples from three breast cancer patients were used as subjects. The C1, C2, and C3a donor were 44, 54, and 55 years old, respectively. C3a and C3b cells were isolated from the same person. Single cell suspension of skin fibroblasts was prepared with primary explant technique. One hundred cells are plated into 100m1 tissue culture flask and cultured for two weeks. The colony size was defined as colonies with 16 or more cells. The cultured cell was stained with crystal violet, and number of cells in each colony was determined with stereo microscope at $\times$10 magnification. Passage number of C1, C2, C3a and C3b skin fibroblast were 12th, 17th, and 14th, respectively. Results : Percentage of colonies with 16 or more cells of skin fibroblast samples decreased with increasing in vitro passage number. In contrast, cumulative population doublings of skin fibroblast sample increased with increasing in vitro passage number. Percentage of colonies with 16 or more cells also decreased with increasing population doublings in human skin fibroblast culture. There was strong correlation with percentage of colonies with 16 or more cells and population doublings En C3a skin fibroblast sampie. At the same point of population doublings, the percentage of colonies with 16 or more cells of the young C1 donor was higher level than the old C3a donor. Conclusion : The population doublings increased with increasing in vitro passage number but percentage of colonies with 16 or more cells decreased. The results of this study imply that percentage of colonies with 16 or more cell is useful as a indicator of in vitro human skin fibroblast aging and may estimate the in vivo donor age.