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Left Ventricular Remodeling in Pediatric Orthotopic Size Mismatched Heart Transplantation  

Lee Seung-Cheol (Department of Thoracic and Cardiovascular Surgery, Division of Pediatric Cardiac Surgery, Asan Medicine Center, University of Ulsan College of Medicine)
Yoon Tae-Jin (Department of Thoracic and Cardiovascular Surgery, Division of Pediatric Cardiac Surgery, Asan Medicine Center, University of Ulsan College of Medicine)
Kim Young-Hwee (Department of Pediatrics, Division of Pediatric Cardiology, Asan Medicine Center, University of Ulsan College of Medicine)
Park In-Sook (Department of Pediatrics, Division of Pediatric Cardiology, Asan Medicine Center, University of Ulsan College of Medicine)
Kim Jong-Wook (Department of Thoracic and Cardiovascular Surgery, Gangneung Asan Hospital, University of Ulsan College of Medicine)
Seo Dong-Man (Department of Thoracic and Cardiovascular Surgery, Division of Pediatric Cardiac Surgery, Asan Medicine Center, University of Ulsan College of Medicine)
Publication Information
Journal of Chest Surgery / v.39, no.3, 2006 , pp. 226-229 More about this Journal
Abstract
Recently, heart transplantation has been accepted as a standard treatment for infant and children with end-stage cardiomyopathy or complex congenital heart disease. Due to the shortage of donors, size-mismatched cardiac transplantation is common. After size-mismatched transplantation, there could be side-effects such as hypertension and hypertensive encephalopathy because of the big-heart. Donor heart is also known to do remodel as time goes by. This is a case report of a size-mismatched heart transplantation between 9-year-old boy and a 39-year-old female whose body weight is almost twice of him. In this case, classical postoperative hypertension and hypertensive encephalopathy developed but was successfully managed. The donor heart has remodeled to normal dimension during 3 years follow-up period.
Keywords
Heart transplantation; Organ weight; Remodeling;
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