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Donor Complication in Living Donor Liver Transplantation

생체간이식에 관한 공여자 합병증

  • Yang, Jae Do (Department of Surgery, Chonbuk National University Medical School) ;
  • Yu, Hee Chul (Department of Surgery, Chonbuk National University Medical School)
  • 양재도 (전북대학교 의학전문대학원 외과학교실) ;
  • 유희철 (전북대학교 의학전문대학원 외과학교실)
  • Received : 2017.12.22
  • Accepted : 2017.12.23
  • Published : 2017.12.30

Abstract

Living donor liver transplantation (LDLT) has become an inevitable procedure due a shortage of deceased donors under the influence of religious and native cultures. The most important concern in LDLT is donor safety. This study reviewed the safety of LDLT donors from reported studies of morbidity and mortality. Many studies have reported mortality and morbidity rates ranging from 0% to 33% for healthy liver donors. Use of laparoscopic surgery on LDLT donors has advantages of reduced blood loss, lower postoperative morbidity and shorter hospital stay relative to conventional open surgery. There is a consensus that remnant liver volume (RLV), degree of steatosis, and donor age are the most important factors influencing donor safety. In LDLT, donor hepatectomy can be performed successfully with minimal and easily controlled complications. However, a large-scale prospective cohort study is needed to better understand the risk factors and accurately determine the complication rates for LDLT.

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Acknowledgement

이 연구는 2016년 대학이식학회 기획과제 연구비의 후원을 받았습니다. 도움을 주신 대한이식학회에 감사 드립니다.