• The Journal of the Korea Contents Association
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• v.18 no.8
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• pp.627-637
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• 2018

The purpose of this study is to develop a plan to improve the status of local autonomous body ordinances applying disability grades according to welfare law for people with disabilities. The results are that First, 215 of the total municipalities applied the disability grade, and 1,071 cases were applied to the disability welfare law. Among them, 60.04% (643 cases) of the ordinance that can be divided into severe (1-3 grade) and mild (4-6 grade) were found, and 39.96% (428 cases). A new service eligibility standard that reflects factors such as the needs of persons with disabilities, social environment, etc. needs to be developed. Second, since the exemption reduction service accounts for more than 40% of all projects, it is necessary to set the standards considering the other standards within the scope of not decreasing the total service amount when revising the ordinance. Based on these results, We will provide important basic data for establishing new service provision criteria to replace the disability level at the local government level.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.12
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• pp.5816-5825
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• 2012

As the society has been ageing, senile dementia increase rapidly. Thus social costs of dementia treatment and management increase exceedingly. There is a desperate need of finding out improvements.. For example, foreign countries come with the solutions about this issue by establishing national strategy about Dementia, setting effective Dementia Management in national level and preparing legal systems. Older Welfare Act, Long Term Care Insurance Act for the Aged and Dementia Management Act exist as legal system of improvements. Improvement about this issue is needed due to more effective Dementia management and pushing ahead policies. First of all, the government needs to include dementia checkup into the list of national health insurance checkup toward senior citizen of older than 65-year-old. Secondly, as one of the characteristics of dementia, when more symptoms of dementia appear, there is less effect of treatment. Therefore, in order to reduce the social costs of Dementia, the government needs to promote Dementia prevention industry and early checkups. Thirdly, there is a need of setting a class judgement standard appeasement policy and expansion of using target. The reason of processing this statement is that there are difficulties of satisfying the needs of senior citizens due to current conformity of long-term pay recuperation according to laws of welfare.

• Journal of Yeungnam Medical Science
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• v.16 no.1
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• pp.69-75
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• 1999

Imidapril(Tanatril$^{(R)}$), a newly developed ACE inhibitor, has been used to treat hypertension and congestive heart failure. This study was designed to assess the antihypertensive effect and safety of Imidapril(Tanatril$^{(R)}$) in patients with essential hypertension. 5-10mg of imidapril(Tanatril$^{(R)}$) was administered once a day in 30 patients with essential hypertension and followed up for 8 weeks. We tested the drug's effectiveness, safety, and the incidence of imidapril induced dry coughs. After 8 weeks of treatment with imidapril, 76.2%(16/21) of patients showed lowered blood pressure and 47.6% showed normal blood pressure. The overall incidence of adverse effects was 33.3%(7/21), and among these adverse effects, dry cough was shown in only 9.5%. Thus, we concluded that imidapril(Tanatril$^{(R)}$) is as safe and effective as other ACE inhibitors, especially with imidapril showing very little incidence of dry cough compared to other ACE inhibitors.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.6
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• pp.2655-2663
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• 2012

The purpose of this study was to investigate psychological separation, depression and antidepressive coping behaviors and to examine the relationship between psychological separation, and depression in Korean university students. The subjects were 131 students who were in 4 university in Chungcheong-do, Korea. The data were collected through self reported structured questionnaire using the psychological separation index, beck depression inventory and antidepressive coping behaviors instrument. The level of depression was classified into; not depressed, 54.2%; mildly depressed, 22.9%; moderately depressed, 16.8%; severely depressed, 6.1%. Among antidepressive coping behaviors, cognitive activity-oriented behaviors was the one with highest percentage(30.8%). Depression was negatively related to functional independence, attitudinal independence, emotional independence from father and conflictual independence from mother. And depression was positively related to conflictual independence from father. These results suggest that it is necessary to develop nursing intervention to strengthen psychological separation form parents and to be able to help desirable antidepressive coping behaviors for the psychological health of university students.

• The Journal of the Korea Contents Association
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• v.9 no.11
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• pp.475-486
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• 2009

Regular activity program is needed for managing chronic disease and obesity and preventing falls as a nursing intervention. It seems that serious game will be very important for older people to keep them active with fun to improve their health. This study was conducted to explore the correlations between health problems and computer game needs in the elderly. This was a cross-sectional study. A questionnaire was developed and administered to a convenience sample of adults who are older than 55 years, recruited from several places through trained research assistants and research center that has online pools in Korea. 778 subjects (mean age: $61.4\;{\pm}\;5.6$) were participated in this study. The majority of subjects was male (68.6%). We found that there was higher needs for exercise or serious game in the group of ma1e(55.4%), below undergraduate(66.2%), under two family members(32.5%), over 350,000 won of pocket money/month (40.1%), mild depressive symptom (51.7%), and online responser(68%). Especially, they wanted to overcome physical limitations through games. Higher education, more experiences and skills of using computer/internet was statistically and positively significant to the needs for exercise or serious game. In conclusion, there exists a potential market within this demographic group for the use of serious games. Thus, we need to develop senior games in Korean to improve quality of life and health promotion.

• Journal of Chest Surgery
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• v.40 no.7 s.276
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• pp.473-479
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• 2007

Background: The Hetzer procedure for the correction of Ebstein's anomaly has the advantages of technical feasibility and incorporation of the atrialized right ventricle (RV) into the functional RV. Material and Method: We preformed a retrospective review of 11 patients with Ebstein's anomaly and they had undergone a Hetzer procedure between March 2002 and December 2006. Result: The median age at operation was 19.8 years (range: 6 months ${\sim}56$ years). There were 4 males and 7 females. All patients showed severe tricuspid regurgitation (TR) preoperatively, and arterial desaturation (<95%) was present in 3 patients. The original Hetzer technique was employed in 6 patients with the Carpentier type A anomaly. In the remaining 5 patients with the Carpentier type B or C anomalies, valve competence was restored at the level of the displaced tricuspid valve mechanism. Adjunct bidirectional cavo-pulmonary shunt, or one and a half ventricle repair strategy was employed for all the patients. The median follow-up was 8.6 months (range: $0.8{\sim}51.9$ months). There was no early or late death, and the immediate postoperative TR was trivial to mild in 8 patients. The median cardio-thoracic ratios on chest X-ray at the preoperative period and at postoperative 0, 1 and 6 months were 65%, 62%, 55% and 55%, respectively. Conclusion: The original or modified Hetzer procedure for Ebstein's anomaly shows excellent intermediate-term outcomes.

• Tuberculosis and Respiratory Diseases
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• v.62 no.4
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• pp.308-313
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• 2007

Background: The nitric oxide (NO) released by inducible NO synthase (iNOS) plays an important role in the pathophysiology of sepsis. Corticosteroids also play a role in the hemodynamic and inflammatory reactions in sepsis. Both have been shown to have a relationship theoretically, but their correlation and clinical impacts have rarely been evaluated. Methods: 26 patients with sepsis and 14 healthy controls were enrolled in this study. The initial random plasma total NO and the serum cortisol levels were measured. The same measurements were serially carried out on the $3^{rd}$, $5^{th}$, and $7^{th}$ days. Results: The initial total plasma levels of NO and cortisol were higher in the patients with sepsis than in the healthy controls. The total NO levels were higher in patients with severe sepsis than in the those with mild sepsis. There was a correlation between the total NO and cortisol level throughout the study. Conclusion: In patients with sepsis, the levels of plasma NO and cortisol were well correlated during the first week of sepsis, which suggests an interrelationship. However, the clinical and pathogenetic implications await further evaluation.

• Proceedings of the Korean Society for Bioinformatics Conference
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• 2004.11a
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• pp.86-100
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• 2004

계산을 통한 단백질 상호작용 예측 기법의 중요성이 제기되면서 많은 단백질 상호 작용 예측 기법이 제안되고 있다. 하지만 이러한 기법들이 일반 사용자가 손쉽게 사용할 수 있는 서비스 형태로 제공되고 있는 경우는 드물다. 본 논문에서는 현재까지 알려진 단백질 상호작용 예측 기법 중 예측 기법의 완성도가 높고 상대적으로 예측 정확도가 높은 것으로 알려진 도메인 조합 기반 단백질 상호 작용 예측 기법을 PreSPI(Prediction System for Protein Interaction)라는 서비스 시스템으로 설계하고 구현하였다. 구현된 시스템이 제공하는 기능은 크게 도메인 조합 기반 단백질 상호 작용 예측 기법을 서비스 형태로 만들어 제공하는 기능으로 입력 단백질 쌍에 대한 상호작용 예측이 중심이 된 핵심기능과, 핵심 기능으로부터 파생되는 기능인 부가 기능, 그리고 주어진 단백질에 대한 도메인 정보검색 기능과 같이 단백질 상호작용에 관하여 연구하는 연구자에게 도움이 되는 일반적인 기능으로 구성되어 있다. 계산을 통해 단백질 상호 작용을 예측하는 시스템은 대규모계산이 요구되는 경우가 많아 좋은 성능을 갖추는 것이 중요하다. 본 논문에서 구현된 PreSPI 시스템은 서비스에 따라 적절히 그 처리를 병렬화 함으로써 시스템의 성능 향상을 도모하였고, PreSPI 가 제공하는 기능을 웹 서비스 API 로 Deploy 하여 시스템의 개방성을 지원하고 있다. 또한 인터넷 환경에서 변화되는 단백질 상호 작용 및 도메인에 관한 정보를 유연하게 반영할 수 있도록 시스템을 계층 구조로 설계하였다. 본 논문에서는 PreSPI 가 제공하는 몇 가지 대표적인 서비스에 관하여 사용자 인터페이스를 중심으로 상술함으로써 초기 PreSPI 사용자가 PreSPI 가 제공하는 서비스를 이해하고 사용하는 데에도 도움이 되도록 하였다.있어서 자각증상, 타각소견(他覺所見)과 함께 이상(異常)은 확인되지 않았으며 부작용도 없었다. 이상의 결과로부터, ‘펩타이드 음료’는 경증고혈압 혹은 경계역고혈압자(境界域高血壓者)의 혈압을, 자각증상 및 혈액${\cdot}$뇨검사에도 전혀 영향을 미치지 않고 저하시킨다고 결론지었다.이병엽을 염색하여 흰가루 병균의 균사생장과 포자형성 등을 관찰한 결과 균사가 용균되는 것을 볼 수 있었으며, 균사의 용균정도와 분생포자형성 억제 정도는 병 방제효과와 일치하는 경향을 보였다.을 의미한다. IV형은 가장 후기에 포획된 유체포유물이며, 광산 주변에 분포하는 석회암체 등의 변성퇴적암류로부터 $CO_{2}$ 성분과 다양한 성분의 유체가 공급되어 생성된 것으로 여겨진다. 정동이 발달하고 있지 않으며, 백운모를 함유하고 있는 대유페그마타이트는 변성작용에 의한 부분용융에 의해 형성된 멜트에서 결정화되었으며, 상당히 높은 압력의 환경에서 대유페그마타이트의 결정화작용 과정에서 용리한 유체의 성분이 전기석에 포획되어 있다. 이때 용리된 유체는 다양한 성분을 지니고 있었으며, 매우 낮은 공융온도와 다양한 딸결정은 포유물 내에 NaCl, KCl 이외에 적어도 $CaCl_{2},\;MgCl_{2}$와 같은 성분을 포함하고 있음을 지시한다. 유체의 용리는 적어도 $2.7{\sim}5.3$ kbar 이상의 압력과 $230{\sim}328^{\circ}C$ 이상의 온도에서 시작되었다.없었다. 결론적으로 일부 한방제와 생약제제는 육계에서 항생제를 대체하여 사용이 가능하며 특히 혈액의 성분에 유의한 영향을 미치는 것으로 사료된다. 실증연구가 필요할 것으로 사료된다.trip과 Sof-Lex disc로 얻어진 표면은 레진전색제의 사용으로 표면조도의 개선

• Korean Journal of Human Ecology
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• v.18 no.6
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• pp.1349-1361
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• 2009

The present study was designed to analyze the relationship of dietary behavior change and nutrient intake status owing to a depression degree for 143 people over 65 years old living in Echeong and Hansan islands area, South Korea. The depression degree was classified into non depression, minor depression and depressive disorder groups using. The Center for Epidemiological Studies-Depression (CES-D) scale for 143 subjects. The results are as follows; the depression degree significantly made differences according to sex (p<.001), marital status (p<.05), self-related economic status (p<.001) and living expenses (p<.05). The stage of dietary behavior according to the depression degree was as follows; the non depression group was 57.6%, the minor group was 46.8% and the depressive disorder group was 27.1% of the subjects. The intake frequency of the cereal group (p<.05) and fruit group (p<.01) was significantly different among food group intake status owing to the depression degree. Mean adequacy ratio(MAR)[13], MAR[10], and MAR[4] of the depressive disorder group were significantly lower than that of the non depression and minor depression groups. Each average of MAR[13], MAR[10], and MAR[4] for the subjects were $0.68{\pm}0.2$, $0.67{\pm}0.2$, and $0.55{\pm}0.2$. Concerned about the nutrients over 1.0 index of nutritional quality(INQ) 8 nutrients of protein, Phosphorous, iron, zinc, vitamin A, vitamin $B_6$, niacin and vitamin C belonged to the non depression group. Additionally, 6 nutrients of protein, Phosphorous, iron, zinc, vitamin $B_6$ and niacin were included for minor depression and depressive disorder groups.

• Journal of fish pathology
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• v.21 no.1
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• pp.35-43
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• 2008

Pathological symptoms and hematological parameters of red sea bream, Pagrus major and water temperature in the culture ground was investigated to clarlify the cause of winter moratility. Dead fish showed green liver and accumulation of ascites in the cavity. A few Bivagina tai were also found on the gill but either bacteria or virus were not. When hematological parameters from fish taken before/after the winter mortality were compared, blood glucose, serum AST and ALT, and total cholesterol, trigyceride and total protein were significantly decreased in the fish after the winter mortality. These results may explain that the nutritional level of fish was decreased because fish could not fed during winter season. According to the CORI monitoring system operating by KODC, NFRDI a long term water temperature from Dec. 25, 2005 to Feb. 24, 2006 (60 days) were exposed the low water temperature environments to the red sea bream. First of all, mass mortality began at Sarayngdo where low temperature below 8℃ continued for 42 days. The winter mortality did not occured in the depths of 9 m to 19.2 m where difference of water temperature in the surface and bottom was only within 0.1℃. But in the depth of 7.5 m to 11 m winter mortality occured where water temperature in the surface and bottom showed much variation ranged from 0.2℃ to 1.4℃. From these results, great difference of water temperature in the surface and bottom of the culturing area might results in winter mortality of red sea bream.