• The Journal of the Petrological Society of Korea
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• v.16 no.3
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• pp.116-128
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• 2007

Detailed geological mapping, petrographic study, analyses of geochemistry and magnetic susceptibility, and K-Ar dating were carried out in order to determine the origin, age, and stratigraphic implications of granitic rock fragments in the pyroclastic rocks, SE Jinhae city, southern part of the Gyeongsang Basin. As a result, it was found that the area is composed of volcanics and tuffaceous sediments of the Yucheon Group, Bulguksa granites, pyroclastics bearing granitic rock fragments, $basalt{\sim}basaltic$ andesite, and rhyolite in ascending stratigraphic order. The granitic rock fragments in the pyroclastic rocks are divided into granodiorite and biotite granite, which have approximately the same characteristics as the granodiorite and the biotite granite of the Bulguksa granites, respectively, in and around the study area including color, grain size, mineral composition, texture (perthitic and micrographic textures), intensity of magnetic susceptibility (magnetite series), and geochemical features (calc-alkaline series and REE pattern). This leads to the conclusion that the rock fragments originated from the late Cretaceous Bulguksa granites abundantly distributed in and around the study area, but not from the basement rocks of the Yeongnam massif or the Jurassic granites. Based on relative and absolute ages of various rocks in the study area, the pyroclastics bearing granitic rock fragments are interpreted to have erupted between 52 and 16 Ma, i.e. during the Eocene and early Miocene. These results indicate that the various volcanisms, acidic to basic in composition, occurred after the intrusion of the Bulguksa granites, contrary to the general stratigraphy of the Gyeongsang Basin. Very detailed and cautious mapping together with relative and absolute age determinations are, thus, necessary in order to establish reliable stratigraphy of the Yucheon Group in other areas of the Gyeongsang Basin.

• The Journal of the Petrological Society of Korea
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• v.25 no.1
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• pp.51-67
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• 2016

Geochemical characteristics of the Early Cretaceous igneous rocks from eastern China and the Gyeongsang Basin, Korean Peninsula has been summarized. They have wide range of lithological variation with extrusive picrite-basalt-andesite-trachyte-rhyolite and lamprophyre, and intrusive gabbro-diorite-monzonite-syenite-granite and diabase in eastern China, mostly belonging to the high-K calc-alkaline or shoshonitic series. The volcanic rocks intercalated with the Hayang Group sedimentary assemblages in the Gyeongsang basin are high-K to shoshonitic basaltic trachyandesites. The Early Cretaceous basaltic rocks studied mostly fall within the field of within-plate basalts on the Zr/Y-Zr and Nb-Zr-Y tectonic discrimination diagrams. On a Sr-Nd isotope correlation diagram, basaltic rocks from the North China block (NCB) and the continent-continent collision zone (CZ) between the North and South China blocks plot into the enriched lower right quadrant along the extension of the mantle array. The initial $^{87}Sr/^{86}Sr$ ratios of basaltic rocks from the South China block (SCB) are indistinguishable from those of the NCB and CZ basaltic rocks, but their ${\varepsilon}_{Nd}$ (t) values are relatively more elevated, plotting in right side of the mantle array. Basaltic rocks from the NCB and CZ are characterized by low $^{206}Pb/^{204}Pb(t)$ ratios, lying to the left of the Geochron on the $^{207}Pb/^{204}Pb(t)$ vs. $^{206}Pb/^{204}Pb(t)$ correlation. Meanwhile, the SCB basaltic rocks have relatively radiogenic Pb isotopic compositions compared with those of the NCB and CZ basaltic rocks. Basaltic rocks from the Hayang Group plot within the field of the NCB basaltic rocks in Sr-Nd and Pb-Pb isotope spaces. Metasomatically enriched subcontinental lithospheric mantle (SCLM) is likely to have been the dominant source for the early Cretaceous magmatism. Asthenospheric upwelling under an early Cretaceous extensional tectonic setting in eastern China and the Korean Peninsula might be a heat source for melting of the enriched SCLM. Metasomatic agents proposed include partial melts of lower continental crust delaminated and foundered into the mantle or subducted Yangtze continental crust, or fluid/melt derived from the subducted paleo-Pacific plate.

• Journal of Life Science
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• v.31 no.4
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• pp.418-424
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• 2021

Skin inflammation (dermatitis) is caused by varying skin damage due to ultraviolet radiation and microbial infection. Currently prescribed drugs for dermatitis include anti-histamine and steroid drug classes that soothe inflammation. However, incorrect or prolonged use of steroids can cause weakening of skin barriers as well as osteoporosis. Therefore, treating dermatitis with a drug that has minimal side effects is important. Statins, also known as 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, are cholesterol-lowering drugs that have been widely treated for hyperlipidemia and cardiovascular diseases. Interestingly, recent studies have shown the anti-inflammatory effects of statins in both experimental and clinical models for of osteoarthritis. This study investigated the possible anti-inflammatory effects of atorvastatin and fluvastatin in human keratinocytes (HaCaT cells), which are crucial components of skin barriers. Stimulation of HaCaT cells with IL-1β increased the expression of the COX2 protein, a major player of inflammatory responses. However, this induction of the COX2 protein was downregulated by pretreatments with atorvastatin and fluvastatin. Treatment with IL-1ß-induced the upregulation of other inflammatory genes (such as iNOS and MMP-1) and these expressions were similarly lowered by these two statin drug treatments. Taken together, these results indicated that atorvastatin and fluvastatin can reduce IL-1β-induced inflammatory responses in HaCaT cells. In conclusion, the findings suggest that atorvastatin and fluvastatin can be potential modulators for ameliorating skin inflammation.

• Journal of radiological science and technology
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• v.34 no.2
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• pp.131-140
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• 2011

This study is to investigate the satisfaction rate and relative factors from the students majored in Radiology, Clinical Pathology and Physical Therapy, which can provide basic knowledge of satisfaction and guide the university life and further careers. The survey was performed with respect to 107 students of Radiology, 97 of Clinical Pathology and 89 of Physical Therapy at three-year or four-year colleges(universities) located in Busan and Gyeongsangnam-do. The results show that the satisfaction rate through whole majors was $3.40{\pm}0.57$ point. The scores of each major are: $3.38{\pm}0.62$ for Radiology, $3.37{\pm}0.56$ for Clinical Pathology, and $3.45{\pm}0.50$ for Physical Therapy. The score of social status was highest and the environment of major was the lowest. The satisfaction of three-year colleges was higher than that of four-year universities. Academic system, social status and adaptation to major affected satisfaction on major. In addition job outlook affected on all majors. Thus, we propose that every major must be equipped with specialized environment different from general colleges (universities), and provide environment where students can cause self-motivation. In addition, we found the special way to improve social status and satisfaction by using career guidance, offering career information and performing university-industry collaborations. Especially, it is important to improve the satisfaction on major of students at four-year universities.

• Economic and Environmental Geology
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• v.10 no.2
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• pp.75-92
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• 1977

Results of 359 chemical analyses of igneous and related rocks of the south Korea were collected from 35 papers to see preliminarily some trends of chemical properties of spatial igneous rock assemblages according to five geotectonic provinces: (1) Kyonggi land, (2) Ryongnam land (on diagram these are jointed together as a massif), (3) Ogcheon zone, (4) Kyongsang basin and (5) Alkali rock province. The data were plotted on the diagrams; $SiO_2$ vs. $Na_2O+K_2O$ and CaO, D. I. vs. oxides, AFM triangle, AKF triangle, and normative An-Ab-Or and Q-Or-Ab triangles for each rock assemblages of individual provinces.

• (The) Research of the performance art and culture
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• no.23
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• pp.313-346
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• 2011

This thesis investigated basic thinking of Pansori reading text appearance. Among Pansori reading texts, it is versions include unfamiliar contents and scenes in text. They was created by writers of Pansori reading text. Why created a writers of Pansori reading text them? First, writers of Pansori reading text created new contents and scenes in order to show their knowledge. Reading texts of this feature are 28pages version Chunhyangjun belonged to Kim Kwang-sun, 87pages version Chunhyangjun belonged to Sa Jae-dong, 154pages version Chunhyangjun belonged to Hong Yun-pyo etc. This reading texts was effected on knowledge culture of Chosun later period. Second, writers of Pansori reading text created new contents and scenes in order to reenact festivities field. Reading texts of this feature are 75pages version Chunhyangjun belonged to Kyungsang university, 52pages version Chunhyangjun belonged to Keimyung university etc. the former shows story field and Pansori field, the latter shows play field of Walja. Third, writers of Pansori reading text created new contents and scenes in order to lampoon yangban authority. Reading texts of this feature are 72pages version Chunhyangjun belonged to Chungnam university and it's affiliation, 59pages version Chunhyangjun belonged to Park Sun-ho and it's affiliation etc.

• Convergence Security Journal
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• v.18 no.5_1
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• pp.113-120
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• 2018

Today, the development of information and communication technology is rapidly increasing the number of users of network-based service, and enables real-time information sharing among users on the Internet. There are various methods in the information sharing process, and information sharing based on portal service is generally used. However, the process of information sharing serves as a cause of illegal activities in order to amplify the social interest of the relevant stakeholders. Public opinion attack using macro function can distort normal public opinion, so security measures are urgent. Therefore, security measures are urgently needed. Macro attacks are generally defined as attacks in which illegal users acquire multiple IP or ID to manipulate public opinion on the content of a particular web page. In this paper, we analyze network path information based on traceback for macro attack of a specific user, and then detect multiple access of the user. This is a macro attack when the access path information for a specific web page and the user information are matched more than once. In addition, when multiple ID is accessed for a specific web page in the same region, it is not possible to distort the overall public opinion on a specific web page by analyzing the threshold count value.

• Clean Technology
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• v.24 no.4
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• pp.293-300
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• 2018

Sulfamethoxazole (SMX) is sulfaamide-based synthetic antibiotics, which are widely prescribed pharmaceutical compound to treat bacterial infections in both human and animals. Most of them are not completely decomposed as refractory substances. The environmental impact of pharmaceuticals as emerging contaminants has generated severe concerns. In this study, catalytic wet peroxide oxidation (CWPO) of SMX was carried out with $Cu/Al_2O_3$ catalyst and investigated the optimum reaction conditions of temperature, dosage of catalyst and concentration of $H_2O_2$ to completely decompose the SMX. It was observed that SMX was completely decomposed within 20 min using 0.79 mM $H_2O_2$ and 6 g $Cu/Al_2O_3$ catalyst at 1 atm and $40^{\circ}C$, but SMX was not fully mineralized and converted to intermediates as hydroylated-SMX, sulfanilic acid, 4-aminobenzenesulfinic acid and nitrobenzene. After that these are completely mineralized through organic acid. We proposed the decomposition reaction path ways of SMX by analyzing the behavior of these intermediates. To investigate the durability of heterogeneous catalyst, decomposition of SMX was observed by continuously recycling catalysts. When the heterogeneous catalyst of 10 wt% $Cu/Al_2O_3$ was continuously reused 5 times, decomposition of SMX was a little lowered, but the activity of catalyst was overall very stable.

• Journal of Life Science
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• v.34 no.9
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• pp.656-665
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• 2024

Enzymes, as proteins that regulate various metabolic processes within the human body, play a crucial role in maintaining health. However, the overexpression of certain enzymes can disrupt metabolic balance, leading to various diseases. Enzyme inhibitors are vital in treating these diseases or conditions by inhibiting the action of these enzymes, making them indispensable in the development of effective therapies for a wide array of diseases. Quercetin, a natural product derived from plants, is a type of flavonoid that belongs to the polyphenol family. Quercetin, a natural flavonoid from the polyphenol family, has emerged as a potent enzyme inhibitor. This low-molecular-weight secondary metabolite is known for its inhibitory effects on enzymes such as α-glucosidase, acetylcholinesterase, bacterial neuraminidase, and xanthine oxidase due to its structural advantages. Quercetin is isolated from biomaterials and can be classified into glycosylated, methoxylated, and alkylated derivatives based on its structural variations. These natural quercetin derivatives possess unique substituents that enable specific binding patterns with catalytic residues in enzyme active sites. Therefore, quercetin derivatives can be expected to have better enzyme inhibitory activity than basic quercetin. Due to their specificity and enhanced activity, quercetin and its derivatives hold promise as candidates for developing potent enzyme inhibitors to treat diseases resulting from enzyme imbalances.

• The Korean Journal of Mycology
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• v.44 no.1
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• pp.23-30
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• 2016

This study was conducted for comparison of ingredients, phytochemical compounds and antioxidant activity of Wofiporia extensa cultured in Gangwon-do, Gyeongsang-do, and Jeolla-do. Three contents of Wofiporia extensa were analyzed as oxygen (46~48%), carbon (38~39%), hydrogen (6.05~6.1%) and nitrogen (0.17~0.21%). The mineral contents of 50% ethanol Wofiporia extensa extracts were measured as sulfur (S) 145~149 ppm, Magnesium (Mg) 69~72 ppm, phosphorus (P) 122~154 ppm and calcium (Ca) 210.61~509.98 ppm. Wofiporia extensa from Gyeongsang-do (509.98 ppm) contained a significantly higher quantity of Ca than that from Gangwon-do (210.62 ppm) and Jeolla-do (223.88 ppm). In the gas chromatograph-mass spectrometry (GC-MS) analysis, oleic acid was identified in three 50% ethanol Wofiporia extensa extracts. In the 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2'-azino-bis-3-ethylbenzothiazoline-6-sulphonic acid (ABTS) assay for antioxidant activity, the $IC_{50}$ values of Wofiporia extensa cultured in Gangwon-do, Gyeongsang-do and Jeolla-do were calculated as 2.966 mg/mL, 23.03 mg/mL, and 4.16 mg/mL and 3.521 mg/mL, 12.17 mg/mL, and 7.40 mg/mL. In the ferric reducing antioxidant power (FRAP) assay, the $IC_{50}$ values of Wofiporia extensa cultured in Gangwon-do, Gyeongsang-do, Jeolla-do were 6.585 mg/mL, 19.06 mg/mL, and 18.97 mg/mL, respectively. In summary, Wofiporia extensa cultured in Gangwon-do had stronger antioxidant activity and higher concentration of oleic acid than that of Geyongsang-do and Jeolla-do. However, Wofiporia extensa cultured in Geyongsang-do contained a much higher concentration of Ca than that of Gangwon-do and Jeolla-do.