• Title/Summary/Keyword: 경로 분할

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One Stage Total Repair of the Aortic Arch Anomaly using the Regional Perfusion (대동맥궁 이상이 동반된 선천성 심장병에서 국소 순환을 이용한 일차 완전 교정)

  • Jang Woo-Sung;Lim Cheong;Lim Hong-Kook;Min Sun-Kyung;Kwak Jae-Kun;Chung Eui-Seuk;Kim Dong-Jin;Kim Woong-Han
    • Journal of Chest Surgery
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    • v.39 no.6 s.263
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    • pp.434-439
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    • 2006
  • Background: Deep hypothermic circulatory arrest during repair of aortic arch anomalies may induce neurological complications or myocardial injury. So we surveyed if the regional cerebral and myocardial perfusion might eliminate those potential side effects. Material and Method: From March 2000 to December 2004, 62 neonates or infants with aortic arch anomaly underwent one stage biventricular repair using the regional perfusion technique by single surgeon. Preoperative diagnosis of the arch anomaly consisted of coarctation (n=46), interruption of the aorta (n=12), hypoplastic left heart syndrome (n=2) and truncus areteriosus (n=2). Combined anomalies were ventricular septal defect (n=51), TAPVR (n=1), PAPVR (n=1) and atrioventricular septal defect (n=2). Arterial cannula was inserted at the innominate artery. Result: The mean regional perfusion time of brain was $28{\pm}10min$. Operative mortality rates was 0 (0/62). Late death was 1 (1/62) during $11{\pm}7$ months of follow-up. Neurologic complications consisted of transient chorea in 1 case. There was no reoperation associated with arch anolamy. Pulmonary complication associated with arch repair occurred in f case which was managed by aortopexy. Conclusion: One-tage rch repair using the regional profusion is safe and effective in minimizing the neurologic and myocardial complications.

Quality Characteristics of the Hamburger Patties with Bamboo (Sasa borealis) Leaf Extract with/without Cooked Rice (조릿대 잎 추출물과 밥을 이용한 햄버거 패티의 품질 특성)

  • Oh, Hyun-Kyung;Lim, Hyeon-Sook
    • Food Science of Animal Resources
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    • v.30 no.5
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    • pp.833-841
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    • 2010
  • This study was conducted to develop patties by substituting a portion of meat by bamboo (Sasa borealis) leaf extract (SBE) and/or cooked rice. Four types of patty were prepared: Control, S, SI, and SII. S was the patty for which 2.5% of meat was substituted with SBE. SI and SII were the patties with 25% or 50%, of meat, respectively, substituted with cooked rice containing SBE. The moisture contents of S, SI, and SII patties were not changed. The compositions of fat, cholesterol, and protein of S, SI, and SII patties were decreased. Cooking loss of weight as well as the diameters of S, SI, and SII patties were decreased. pH was increased in S patty, hardness was reduced in SI and SII patties, and malondialdehyde values were lowered in S, SI, and SII patties, compared to control. The S, SI, and SII patties were evaluated higher for color in sensory tests and preference tests. Through preference tests of burgers with these patties, the overall taste of the SI patty was assessed highly among the 4 patties. Therefore, it may be concluded that developing a patty by substituting a portion of meat with SBE and/or cooked rice may be worthwhile.

Low Volume Peritoneal Dialysis in Newborns and Infants (신생아와 영아의 급성신부전증 치료를 위한 저용량 복막투석)

  • Park, Young-Hoon;Ahn, Soo-Ho;Shin, Son-Moon;Hah, Jeong-Ok
    • Journal of Yeungnam Medical Science
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    • v.8 no.2
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    • pp.128-137
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    • 1991
  • Peritoneal dialysis has been widely considered to be the dialytic treatment of choice for acute renal failure in infants and young children, because the technique is simple, safe and easily adapted for these patients. Also peritoneal dialysis in infants might have more effective ultrafiltration and clearance than in adults. In certain circumstances associated with hemodynamic instability, ordinary volume peritoneal dialysis(30-50 ml/kg body weight per exchange) or hemodialysis may not be suitable unfortunately. But frequent cycled, low volume, high concentration peritoneal dialysis may be more available to manage the hemodynamically untable acute renal failure of newborns and infants. Seven infants underwent peritoneal dialysis for hemodynamically unstable acute renal failure with low exchange volume($14.2{\pm}4.2ml/kg$), short exchange time(30 to 45 minutes) and hypertonic glucose solution(4.25% dextrose). Age was $1.9{\pm}1.3$ months and body weight was $4.6{\pm}1.6kg $. Etiology of acute renal failure was secondary to sepsis with or without shock(5 cases) and postcardiac operation(2 cases). Catheter was inserted percutaneously with pigtail catheter or Tenkhoff catheter by Seldinger method. Dialysate was commercially obtained Peritosol which contained sodium, chloride, potassium, magnesium, lactate and calcium. Net ultrafiltration(ml/min) showed no difference between low volume dialysis and control($0.27{\pm}0.09$ versus $0.29{\pm}0.09$) Blood BUN decreased from $95.7{\pm}37.5$ to $75.7{\pm}25.9mg/dl$ and blood pH increased from $7.122{\pm}0.048$ to $7.326{\pm}0.063$ after 24 hours of peritoneal dialysis. We experienced hyperglycemia which were controlled by insulin(2 episodes), leakage at the exit site(2), mild hyponatremia(1) and Escherichia coli peritonitis(1). Two children of low volume dialysis died despite the treatment. In our experience, low volume and high concentration peritoneal dialysis with frequent exchange may have sufficient ultrafiltration and clearance without significant complications in the certain risked acute renal failure of infants.

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The Neuroprotective Effects of 6-cyano-7-nitroquinoxalin-2,3-dione (CNQX) Via Mediation of Nitric Oxide Synthase on Hypoxic-ischemic Brain Injury in Neonatal Rats

  • Jung, Ji-Eun;Keum, Kyung-Hae;Choi, Eun-Jin;Kim, Jin-Kyung;Chung, Hai-Lee;Kim, Woo-Taek
    • Neonatal Medicine
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    • v.18 no.1
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    • pp.59-69
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    • 2011
  • Purpose: Current studies have demonstrated the neuroprotective effects of 6-cyano-7-nitroquinoxalin-2,3-dione (CNQX) in many animal models of brain injury, including hypoxic-ischemic (HI) encephlopathy, trauma and excitotoxicity, but limited data are available for those during the neonatal periods. Here we investigated whether CNQX can protect the developing rat brain from HI injury via mediation of nitric oxide synthase. Methods: In an in vivo model, left carotid artery ligation was done in 7-day-old Sprague-Dawley (SD) rat pups. The animals were divided into six groups; normoxia (N), hypoxia (H), hypoxia with sham-operation (HS), hypoxia with operation (HO), HO treated with vehicle (HV), and HO treated with CNQX at a dose of 10 mg/kg (HC). Hypoxia was made by exposure to a 2 hr period in the hypoxic chamber (92% $N_2$, 8% $O_2$). In an in vitro model, embryonic cortical neuronal cell culture of SD rats at 18-day gestation was done. The cultured cells were divided into three groups: normoxia (N), hypoxia (H), and hypoxia treated with CNQX (HC). The N group was prepared in 5% $CO_2$ incubators and the other groups were placed in 1% $O_2$) incubators (94% $N_2$, 5% $CO_2$) for 16 hr. Results: In the in vitvo and in vivo models, the expressions of iNOS and eNOS were reduced in the hypoxia group when compared to the normoxia group, whereas they were increased in the CNQX-treated group compared to the hypoxia group. In contrast, the expression of nNOS was showed reversely. Conclusion: CNQX has neuroprotective property over perinatal HI brain injury via mediation of nitric oxide synthase.

Development of Periventricular Leukomalacia and Severe Intraventricular Hemorrhage in Very Low Birth Weight Newborns and Relationship with Ventilator Care (Study of Ventilator Care as a Risk Factor of PVL and PV-IVH) (극소저출생체중아의 뇌실주위백질연화증과 중증뇌실출혈의 발생과 인공호흡기 치료와의 상관관계)

  • Lee, Hak Sung;Lee, Sae Kyu;Kim, Yeong Jin;Lee, Sang Geel
    • Clinical and Experimental Pediatrics
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    • v.48 no.12
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    • pp.1330-1336
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    • 2005
  • Purpose : It has been suggested that changes in cerebral blood flow by ventilator care could be a risk factor in periventricular leukomalacia(PVL) and severe periventricular-intraventricular hemorrhage(PV-IVH). The study aims to assess the relationship between perinatal clinical events, including ventilator care, and the development of PVL and severe PV-IVH; especially, whether ventilator care could be causers of PVL and severe PV-IVH as an individual risk factor. Methods : Among 255 very low birth weight infants who survived in the Fatima neonatal intensive care unit from January 1999 to December 2003, 15 infants with PVL and eight infants with severe PV-IVH were classified as a study group, while 231 infants were enrolled as a control group. The analysis was performed retrospectively with medical records. Results : Twenty four infants were diagnosed with PVL or severe PV-IVH. Asphyxia, recurrent apnea, sepsis, acidosis and ventilator care were significantly increased in the PVL goup. Asphyxia, recurrent apnea, RDS, acidosis and ventilator care were significantly increased in the severe PV-IVH group. Conclusion : Infants with PVL or severe PV-IVH may have multiple perinatal risk factors including asphyxia, recurrent apnea, sepsis, acidosis, RDS and ventilator care. Because most patients with ventilator care have multiple perinatal risk factors, ventilator care does not cause PVL and severe PV-IVH independently. Therefore, incidences of PVL and severe PV-IVH can be decreased by not only gentle ventilation, but also more professional antenatal care.

The Comparison between Single Shot Turbo Spin Echo and B-FFE (Balanced Turbo Field-echo) in the Differentiation of Focal Liver Lesions (국소 간병변 감별에서 단발고속스핀에코 기법과 균형항정상 태세차를 이용한 고속영역 기법간의 비교)

  • Kim, Young-Chul;Kim, Myeong-Jin;Cha, Seung-Whan;Chung, Yong-Eun;Han, Kwang-Hyup;Choi, Jin-Sub
    • Investigative Magnetic Resonance Imaging
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    • v.11 no.1
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    • pp.39-48
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    • 2007
  • Purpose : To determine the diagnostic accuracy of four different sequences : moderately T2 weighted, two heavily T2-weighted single shot turbo spin-echo sequence and breath-hold axial-2D balanced turbo field-echo sequence(bFFE) for characterization of focal lesions. Materials and Methods : During the 3-month period between June and August 2005, seventy-six patients were proved to have ninety-three focal hepatic lesions on MR imaging. The patients consisted of 49 men and 27 women (age range, 15-75 years; mean age, 56.23 years). All MR images were acquired on a 1.5-T MR using the following sequences: 1. A breath-hold axial T2-weighted single shot turbo spin-echo sequence, 2. a breath-hold axial-2D balanced turbo field-echo sequence. Two radiologists performed quantitative analysis. Another radiologist measured the lesion-to-liver contrast-to-noise ratio at the region-of-interest in the four sequences. Results : There was no significant difference in inter-observer variability between the four sequences. The accuracy for both cyst and malignancy of moderate T2 weighted MRI (echo time: 80 msec) was also highest. There was significant difference for lesion characterization between moderate T2 weighted MRI and balanced steady state procession (p-value: 0.004) in the second reader. For longer echo time, the CNR of cystic lesions were markedly increased in comparison to lesions of other component. Conclusion : The accuracy and inter-observer variability of single shot turbo spin echo T2 weighted sequence was higher than bFFE. Although there was no statically significant difference, moderate T2 weighted MRI (echo time: 80 msec) was more accurate than heavily T2 weighted sequence (echo time: 300 msec). If the results for lesion characterization is equivocal in TE 80, the addition of heavily T2 weighted MRI (echo time: 180 msec) can be helpful.

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Effects of Addition of Perilla Leaf Powder and Carcass Grade on the Quality and Palatability of Pork Sausage (깻잎 분말 첨가와 도체등급이 돈육소시지의 품질 및 기호성에 미치는 영향)

  • 정인철;강세주;김종기;현재석;김미숙;문윤희
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.32 no.3
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    • pp.350-355
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    • 2003
  • This study was carried out to clarify the effect of addition of perilla leaf powder (PLP) and carcass grade on the quality and palatability of pork sausage. The chemical composition, pH, calorie, water holding capacity, surface color, textural properties and amino acid composition of the samples were determined, and sensory characteristics were evaluated. Moisture and crude ash were not different among sausage of four type. Crude fat of grade B sausage was higher than that of grade E sausage, and grade B sausage added PLP was higher than grade B sausage without PLP. Crude Protein of grade E sausage was higher than that of grade B sausage. The pH of grade E sausage added PLP was highest, and calorie of grade B sausage without PLP was highest among sausage of four type. Water holding capacity of grade B added and free PLP was significantly higher than grade I sausage. The residual nitrite of sausage added PLP was significantly lower than sausage without PLP. In case of Hunter's $L^{*}$, grade B sausage and free PLP sausage were significantly higher than grade E sausage and sausage added PLP, respectively. In case of Hunter' $a^{*}$, grade E sausage and free PLP sausage were significantly higher than grade B sausage and sausage added PLP. Hunter's $b^{*}$ of sausage added PLP was higher than that of free PLP sausage. Textural properties, hardness, springiness, cohesiveness and chewiness were significantly different among sausage of four type, but gumminess of grade E added PLP was lowest among sausage of four type. Total amino acid was not significantly different among sausage of four type. Sensory color and texture of grade B sausage were superior to grade I sausage, palatability of free PLP sausage was superior.sage was superior.

Relationship between the Catches of Tuna and Oceanographic Conditions in the South-East Pacific (남동 태평양의 참치 어획양과 해양환경과의 관계)

  • CHO Kyu-Dae;KIM Yun-Ae;PARK Sung-Woo;KIM Jae-Chul;PARK Jae-Chul
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.20 no.4
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    • pp.360-369
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    • 1987
  • The relationship between the catches of tuna and hydrographic conditions in South-East Pacific region (latitude $5^{\circ}N-12^{\circ}S$, longitude $135^{\circ}W-115^{\circ}W$) was investigated by using the catch data of tuna and Digital Bathythermograph (DBT) data from December 9, 1980 to April 2, 1981. The results are as follows : The study area were located in South Eguatorial Current regions including equatorial upwelling regions in $5^{\circ}N\;to\;12^{\circ}S$. The horizontal mean temperature at the depth of 10m on the first quarter months in the study area was about $25^{\circ}C$C and the salinity of those fishing areas ranged from 34.8 to $35.0\%_{\circ}$. Yellowfin tuna and bigeye tuna were mainly caught in SW vertical temperature profile type, which the depth of thermocline ranged from loom to 300m, and temperature difference of thermocline was about $12^{\circ}C$. The deeper the depth of thermocline, the more the catches of tuna. While albacore tuna was caught well in SS vertical temperature profile type which the temperature of thermocline ranged from $9^{\circ}\;to\;26^{\circ}C$ and its gradient was very smooth. The depth of 1 ml/l surface of dissoved oxygen content ranged from loom to 200m in the South-East Pacific between longitude $140^{\circ}W-100^{\circ}W$, but it was shallower than 100 m near the North-South American continent. The catches of bigeye tuna were larger than those of yellowfin tuna in South Equatorial Current region. As approaching to the South and North American continent, the catches of yellowfin tuna and bigeye tuna decreased because the thermocline becomes shallower and steeper and the depth of the 1 m1/1 surface of dissolved oxygen content became shallower.

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Residue of Pesticides Carbendazim and Chlorpyrifos in Different Parts of Red Pepper (고추의 부위별 카벤다짐과 클로르피리포스의 잔류 양상)

  • Park, Hae-In;Hwang, Jae-Moon;Kim, Byung-Soo;Lee, Mi-Gyeong;Chol, Young-Wook;Lee, Min-Ho;Jeong, Jeong-Eun;Kim, Jeong-Han
    • The Korean Journal of Pesticide Science
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    • v.15 no.3
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    • pp.246-253
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    • 2011
  • This experiment was carried out to examine the residual amount variation of carbendazim and chlorpyrifos in fruit parts of red pepper according to the open field and/or the rain shelter house. It was shown higher residual amounts of agrochemicals in the field than the house condition at two hours (0 day) after chemical application, but it was shown higher residual amounts in the house at 5 days and 10 days. Although the residual amount in the field was higher than in the house at the beginning, the chemicals fast degraded in field condition. Carbendazim and chlorpyrifos remained as time passed in order of receptacle, but the residual amounts of two chemicals in leaf at $5^{th}$ day. Carbendazim and chlorpyrifos were lessened until 10 days after chemical application, and reduction rate were 19.1% and 66.4% in flesh, 45.2% and 62.3% in receptacle, and 41.6% and 72.0% in the stalk, respectively. The reduction rate at 15 days showed 31.1%, 75.3% in flesh, 43.5%, 81.7% in receptacle, and 47.7%, 82.8% in stalk, respectively. Therefore the reduction rate of carbendazim showed receptacle > stalk > flesh, and that of chlorpyrifos showed stalk > receptacle > flesh in order. The calculated half-life of carbendazim showed 29.6 days in flesh, 13.6 days in receptacle, and 16.0 days in stalk, but that of chlorpyrifos showed 8.3 days in flesh, 8.3 days in receptacle, and 6.3 days in stalk. In conclusion, the half-life of carbendazim was longer than that of chlorpyrifos in even part, and especially was longest in flesh part of fruit.

Effects of Noise and Vibration on Oxygen Consumption and Ammonia Excretion in Cultured Catfish (Silurus asotus) (양식장에서 사육하는 메기 (Silurus asotus)의 산소소비 및 암모니아 배설에 미치는 소음진동 영향)

  • Hur, Jun Wook;Lee, Jeong Yeol;Joo, Jin Chul
    • Ecology and Resilient Infrastructure
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    • v.5 no.2
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    • pp.105-109
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    • 2018
  • The main objective of this investigation was to examine oxygen consumption and ammonia excretion within cultured catfish, Silurus asotus ($22.9{\pm}0.9cm$, $100.7{\pm}11.7g$ n = 30) by noise and vibration stress in aquaculture farm. The vibration of 48, 58 and 68 dB (V) and noise of $77.6{\pm}1.8dB$ (A) from an electric vibrator was turned on for 15 minutes during each hour each day(0800-1800) for 11 days experimental period. The oxygen consumption (OC) of S. asotus the beginning of the experiment (0 day) in 58 dB group after 1, 5, 9 and 11 days was decreased 21.8, 30.2, 36.0 and 53.2%, respectively. In 68 group after 1, 7 and 11 days was decreased 22.7, 35.1 and 57.7%, respectively. The OC decreased exponentially and the relationship between them was expressed as OC = 0.374D + 90.762 ($r^2=0.048$) at 48 dB, OC = -3.581D + 89.520 ($r^2=0.831$) at 58 dB and OC = -4.109D + 90.907 ($r^2=0.884$) at 68 dB. Ammonia excretion (AE) of the beginning of the experiment in 48, 58 and 68 groups after 1 day was increased by 34.8, 51.8 and 63.2%, respectively, but it was decreased significantly from 3 to 11 days. The AE increased exponentially and the relationship between them was expressed as AE = -1.646D + 115.915 ($r^2=0.265$) at 48 dB, AE = -8.230D + 122.132 ($r^2=0.750$) at 58 dB and AE = -7.086D + 123.690 ($r^2=0.614$) at 68 dB.