References
- Vannucci RC, Perlman JM. Interventions for perinatal hypoxicischemic encephalopathy. Pediatrics 1997;100:1004-14. https://doi.org/10.1542/peds.100.6.1004
- Monaghan DT, Bridges RJ, Cotman CW. The excitatory amino acid receptors: their classes, pharmacology, and distinct properties in the function of the central nervous system. Annu Rev Pharmacol Toxicol 1989;29:365-402. https://doi.org/10.1146/annurev.pa.29.040189.002053
- Varju P, Schlett K, Eisel U, Madarasz E. Schedule of NMDA receptor subunit expression and functional channel formation in the course of in vitro-induced neurogenesis. J Neurochem 2001;77: 1444-56. https://doi.org/10.1046/j.1471-4159.2001.00352.x
- Dingledine R, Borges K, Bowie D, Traynelis SF. The glutamate receptor ion channels. Pharmacol Rev 1999;51:7-61.
- Nikam SS, Kornberg BE. AMPA receptor antagonists. Curr Med Chem 2001;8:155-70. https://doi.org/10.2174/0929867013373877
- Alabadi JA, Thibault JL, Pinard E, Seylaz J, Lasbennes F. 7- Nitroindazole, a selective inhibitor of nNOS, increases hippocampal extracellular glutamate concentration in status epilepticus induced by kainic acid in rats. Brain Res 1999;839:305-12. https://doi.org/10.1016/S0006-8993(99)01749-7
- Moncada S, Palmer RM, Higgs EA. Biosynthesis of nitric oxide from L-arginine. A pathway for the regulation of cell function and communication. Biochem Pharmacol 1989;38:1709-15. https://doi.org/10.1016/0006-2952(89)90403-6
- Heales SJ, Bolanos JP, Stewart VC, Brookes PS, Land JM, Clark JB. Nitric oxide, mitochondria and neurological disease. Biochim Biophys Acta 1999;1410:215-28. https://doi.org/10.1016/S0005-2728(98)00168-6
- Sengpiel B, Preis E, Krieglstein J, Prehn JH. NMDA-induced superoxide production and neurotoxicity in cultured rat hippocampal neurons: role of mitochondria. Eur J Neurosci 1998;10:1903- 10. https://doi.org/10.1046/j.1460-9568.1998.00202.x
- Patel M, Li QY. Age dependence of seizure-induced oxidative stress. Neuroscience 2003;118:431-7. https://doi.org/10.1016/S0306-4522(02)00979-X
- Gunasekar PG, Kanthasamy AG, Borowitz JL, Isom GE. NMDA receptor activation produces concurrent generation of nitric oxide and reactive oxygen species: implication for cell death. J Neurochem 1995;65:2016-21.
- Iwasaki Y, Ikeda K, Shiojima T, Kinoshita M. CNQX prevents spinal motor neuron death following sciatic nerve transection in newborn rats. J Neurol Sci 1995;134:21-5. https://doi.org/10.1016/0022-510X(95)00217-6
- Zhou Y, Zhou L, Chen H, Koliatsos VE. An AMPA glutamatergic receptor activation-nitric oxide synthesis step signals transsynaptic apoptosis in limbic cortex. Neuropharmacology 2006;51:67-76. https://doi.org/10.1016/j.neuropharm.2006.03.002
- Radenovic L, Selakovic V. Differential effects of NMDA and AMPA/kainate receptor antagonists on nitric oxide production in rat brain following intrahippocampal injection. Brain Res Bull 2005; 67:133-41. https://doi.org/10.1016/j.brainresbull.2005.06.019
- Levine S. Anoxic-ischemic encephalopathy in rats. Am J Pathol 1960;36:1-17.
- Brewer GJ. Isolation and culture of adult rat hippocampal neurons. J Neurosci Methods 1997;71:143-55. https://doi.org/10.1016/S0165-0270(96)00136-7
- Calvert JW, Zhang JH. Pathophysiology of an hypoxic-ischemic insult during the perinatal period. Neurol Res 2005;27:246-60. https://doi.org/10.1179/016164105X25216
- Delivoria-Papadopoulos M, Mishra OP. Mechanisms of cerebral injury in perinatal asphyxia and strategies for prevention. J Pediatr 1998;132:S30-4. https://doi.org/10.1016/S0022-3476(98)70525-6
- Gunn AJ, Gunn TR. The 'pharmacology' of neuronal rescue with cerebral hypothermia. Early Hum Dev 1998;53:19-35. https://doi.org/10.1016/S0378-3782(98)00033-4
- Matute C, Sanchez-Gomez MV, Martinez-Millan L, Miledi R. Glutamate receptor-mediated toxicity in optic nerve oligodendrocytes. Proc Natl Acad Sci U S A 1997;94:8830-5. https://doi.org/10.1073/pnas.94.16.8830
- Dirnagl U, Iadecola C, Moskowitz MA. Pathobiology of ischaemic stroke: an integrated view. Trends Neurosci 1999;22:391-7. https://doi.org/10.1016/S0166-2236(99)01401-0
- Komuro H, Rakic P. Modulation of neuronal migration by NMDA receptors. Science 1993;260:95-7. https://doi.org/10.1126/science.8096653
- Kawasaki H, Morooka T, Shimohama S, Kimura J, Hirano T, Gotoh Y, et al. Activation and involvement of p38 mitogen-activated protein kinase in glutamate-induced apoptosis in rat cerebellar granule cells. J Biol Chem 1997;272:18518-21. https://doi.org/10.1074/jbc.272.30.18518
- Ashwal S, Pearce WJ. Animal models of neonatal stroke. Curr Opin Pediatr 2001;13:506-16. https://doi.org/10.1097/00008480-200112000-00003
- Ignarro LJ. Biosynthesis and metabolism of endothelium-derived nitric oxide. Annu Rev Pharmacol Toxicol 1990;30:535-60. https://doi.org/10.1146/annurev.pa.30.040190.002535
- Bult H, Boeckxstaens GE, Pelckmans PA, Jordaens FH, Van Maercke YM, Herman AG. Nitric oxide as an inhibitory non-adrenergic non-cholinergic neurotransmitter. Nature 1990;345:346-7. https://doi.org/10.1038/345346a0
- Garthwaite J, Garthwaite G, Palmer RM, Moncada S. NMDA receptor activation induces nitric oxide synthesis from arginine in rat brain slices. Eur J Pharmacol 1989;172:413-6. https://doi.org/10.1016/0922-4106(89)90023-0
- Bredt DS, Hwang PM, Glatt CE, Lowenstein C, Reed RR, Snyder SH. Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase. Nature 1991;351:714 -8. https://doi.org/10.1038/351714a0
- Dienel GA, Hertz L. Astrocytic contributions to bioenergetics of cerebral ischemia. Glia 2005;50:362-88. https://doi.org/10.1002/glia.20157
- Dawson TM, Bredt DS, Fotuhi M, Hwang PM, Snyder SH. Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues. Proc Natl Acad Sci U S A 1991;88:7797- 801. https://doi.org/10.1073/pnas.88.17.7797
- Lamas S, Marsden PA, Li GK, Tempst P, Michel T. Endothelial nitric oxide synthase: molecular cloning and characterization of a distinct constitutive enzyme isoform. Proc Natl Acad Sci U S A 1992;89:6348-52. https://doi.org/10.1073/pnas.89.14.6348
- Lowenstein CJ, Dinerman JL, Snyder SH. Nitric oxide: a physiologic messenger. Ann Intern Med 1994;120:227-37. https://doi.org/10.7326/0003-4819-120-3-199402010-00009
- Galea E, Reis DJ, Feinstein DL. Cloning and expression of inducible nitric oxide synthase from rat astrocytes. J Neurosci Res 1994;37: 406-14. https://doi.org/10.1002/jnr.490370313
- Samdani AF, Dawson TM, Dawson VL. Nitric oxide synthase in models of focal ischemia. Stroke 1997;28:1283-8. https://doi.org/10.1161/01.STR.28.6.1283
- Forman LJ, Liu P, Nagele RG, Yin K, Wong PY. Augmentation of nitric oxide, superoxide, and peroxynitrite production during cerebral ischemia and reperfusion in the rat. Neurochem Res 1998;23: 141-8. https://doi.org/10.1023/A:1022468522564
- Iadecola C, Zhang F, Casey R, Nagayama M, Ross ME. Delayed reduction of ischemic brain injury and neurological deficits in mice lacking the inducible nitric oxide synthase gene. J Neurosci 1997; 17:9157-64.
- Stagliano NE, Dietrich WD, Prado R, Green EJ, Busto R. The role of nitric oxide in the pathophysiology of thromboembolic stroke in the rat. Brain Res 1997;759:32-40. https://doi.org/10.1016/S0006-8993(97)00200-X
- Dimmeler S, Dernbach E, Zeiher AM. Phosphorylation of the endothelial nitric oxide synthase at ser-1177 is required for VEGFinduced endothelial cell migration. FEBS Lett 2000;477:258-62. https://doi.org/10.1016/S0014-5793(00)01657-4
- Higuchi Y, Hattori H, Kume T, Tsuji M, Akaike A, Furusho K. Increase in nitric oxide in the hypoxic-ischemic neonatal rat brain and suppression by 7-nitroindazole and aminoguanidine. Eur J Pharmacol 1998;342:47-9. https://doi.org/10.1016/S0014-2999(97)01524-0
- Tsuji M, Higuchi Y, Shiraishi K, Kume T, Akaike A, Hattori H. Protective effect of aminoguanidine on hypoxic-ischemic brain damage and temporal profile of brain nitric oxide in neonatal rat. Pediatr Res 2000;47:79-83. https://doi.org/10.1203/00006450-200001000-00015