• 여성건강간호학회지
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• 제4권3호
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• pp.332-347
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• 1998

This study was performed for the purpose of analyzing the relationship of menopausal symptoms of midlife women between urban area and rural area. A total of 129 midlife women who have lived in seoul, Kyeung ki and Kangwon were selected conveniently and data were collected by structured questionnaire from May to June, 1998. The instruments were the menopausal symptoms scale developed by Neugarten, Ci Sung-Ai & Kim Hy-Eun. Data analysis was done by Chi-square test, ANOVA, t-test. The results of this study were summarized as follows ; 1. The mean score for the menopausal symptoms of midlife women was 2.12. Serious menopausal symptoms which could be found in this study were "joint pain and numbness of arm and leg"(2.63), "fatigue and powerlessness"(2.58), "nervousness"(2.44). Over 97.8% of women complained menopausal symptoms. 2. In the relationship between social demographic variables and menopausal symptoms of midlife women were significant difference in urban area and rural area(t=-4.569, P=.000), marriage status(F=4.809, P=.010), education(F=7.359, P=.000), married son and daughter(F=7.359, P=.000), mensturational status(F=5.993, P=.003), and satisfaction to husband(F=9.093, P=.000). 3. In the relationship of menopausal symptoms of midlife women between two groups were statistically significant differences(t=-4.569, P=.000). The mean score of menopausal symptoms of rural women(2.34) were higher than those of urban women(1.85). This study shows the possible implication for nursing intervention of midlife women's health to prevent and relieve menopausal symptoms.

• 여성건강간호학회지
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• 제4권1호
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• pp.47-66
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• 1998

The purpose of this study is to investigate the relationship between menopausal symptoms and spiritual well-being. In order to collect the research data, 350 questionaries were sent to the middle aged women who were 40-59 years old. During the collection period, March 20, 1977-April 20, 1977, 264 questionaries were collected. The questionnaire was prepared by using other researchers' scale, such as menopausal symptom scale by Neugarton and spiritual well-being scale by Paloutzian & Ellison. The research data were analyzed by various testable methods, such as frequency, t-test or ANOVA, and Pearson's correlation. The main results of this study were as follows ; Among the general characteristic variables, some variables have statistical significancy in explaining the difference of the menopausal symptoms. Such variables include age(F=5.17, p=0.002), years get married(F=4.23, p=0.002), number of children(F=3.08, p=0.028), income level of family(F=3.07, p=0.017), life style at leisure time(F=2.47, p=0.045). Some variables related to health condition could explain the differences of the menopausal symptoms among middle aged women. current menstruation stage(F=9.82, p=0.000), current health condition(F=9.82, p=0.000), and experience being operated in the past(F=9.82, p=0.000) are related to the menopausal symptoms. Serious menopausal symptoms which could be found in this study were 'back pain and joint pains(2.6)', nervousness(2.4), and psychosomatic symptom(1.97). Spiritual well-being inquiries could be classified into two subgroups, existential and religious. The mean score of existential well-being(3.04) was higher than that of religious well-being(2.76). Relatively higher existential well-being(3.10) was found in the women who have stable menstruation cycle. The age when the menopause began was related to spiritual well-being(F=3.29, p=0.046). The correlation between menopausal symptoms and spiritual well-being was statistically significant(r=-0.133, p=0.031). Based on the above results, nursing intervention program of menopausal symptoms is recommended in order to promote the health of middle-aged women.

• 여성건강간호학회지
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• 제7권4호
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• pp.642-656
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• 2001

The purpose of this study is to find the difference of the climacteric symptoms and quality of life according to hormone replacement therapy (HRT) in climacteric women. The research design was a descriptive survey with questionaries. A convenience sample of 181 climacteric women aged 45-65 who had climacteric symptoms were selected in Kwangju city, Korea. Sixty-six climacteric women among those subjects were receiving HRT at K university hospital in Kwangju city. Data were collected by the interview with questionaries from Feb 3. 1999 to March 25, 1999. Climacteric symptoms were measured using scores developed by Neugarten(1965) and modified by Park(1989), and the quality of life scale related to climacteric symptoms developed by Hildtich(1996) and modified Kim(1998). Data were analyzed by $x^2$-test, t-test, ANOVA and Pearson's correlation procedures, using SAS/win PC+. The results were as follows ; 1. No statistically significant differences were found between the receiving HRT group and not receiving HRT group in demographic, obstetrical and health related characteristics. 2. There were no significant difference on the climacteric symptoms between the group of women receiving HRT (score 2.4) and the group of women who were not (score 2.6) except psychological area (t= 2.407, p= 0.017). 3. The quality of life of the group of women receiving HRT was significantly higher than that the group of women who were not (t=2.151, p=.032). 4. The quality of life of the group of women receiving HRT were high scores There were significantly high of the quality of life in the vaso-motor change area (t=2.634, p= 0.009), psycho-social change area (t=3.239, p=0.001), and physical change area (t=2.031, p=0,043) in the group of receiving HRT compared to not receiving HRT group. 5. The variables showed significantly differences on the degree of climacteric symptoms of the group of women not receiving HRT were the subjective health state (t=15.81, p=0.000), age (t=7.50, p=0.007), feeling of menopause (t=30.88, p=0,000) and climacteric periods (t=8.66, p=0.003), and receiving HRT were number of para (t=3.95, p=0.050) and feeling of menopause (t=3.94, p=0.050). 6. The variables showed significantly difference on the quality of life of the group of women not receiving HRT were the subjective health state (t=4.14, p=0.044) and feeling of menopause (t=10.86, p=0.001). 7. There were significantly positive correlations between the climacteric symptoms and the quality of life in climacteric women (r=0.512, p=0.000).

• 대한가정학회지
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• 제40권1호
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• pp.125-134
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• 2002

The purpose of this study was to investigate relationship between the climacteric symptoms and the dietary patterns. The study was conducted with 285 middle-aged women(150 premenopause and 135 postmenopause) and the informations were obtained by questionnaires. The menophania of the premenopause and of the postmenopause women began to 15.6 and 16.6 years old, respectively. And it seemed that the middle-aged women had neutral attitude about menopause-related altitude. There was a positive correlation between the nutrition knowledge and the food habit, but these knowledge and habits had a little correlation with the climacteric symptoms.

• 한국식품영양과학회지
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• 제44권4호
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• pp.506-515
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• 2015

본 연구는 난소 적출 동물 모델을 이용하여 고흥산 석류 농축액 시험군과 함께 이란산 석류 농축액을 주성분으로 하는 시판 제품의 혈청 생화학적 지표, 골밀도 등 몇 가지 지표를 분석하여 갱년기 증상 개선 효과를 비교하였다. 고흥산 석류 농축액과 시판 제품은 난소 절제 동물 모델의 골밀도(bone mineral density, BMD) 및 percent bone volume(bone volume/tissue volume), bone surface density(bone surface/tissue volume)를 증가시켰으며, 특히 고용량의 고흥산 석류 농축액(PE3)은 통계적으로 유의하게 골밀도 및 골볼륨을 증가시켰다. 시판 제품을 투여한 군도 골밀도를 증가시키는 양상을 보였으나 통계적 유의성은 없어 고흥산 석류 농축액이 이란산 석류 제품보다 골밀도 등 뼈 건강에 관련한 갱년기 증상 개선에 더 효과적이라고 사료된다. 고흥산 석류 농축액은 난소 절제에 의한 체중 증가 및 복부/내장지방 축적을 개선하였으며, 농도 의존적으로 HDL-C(high density lipoprotein cholesterol)는 증가시키고 low density lipoprotein cholesterol은 감소시켰다. 또한 고농도 석류 농축액(PE3)의 HDL-C/total cholesterol이 통계적으로 유의하게 증가하여 고흥산 석류 농축액이 갱년기 여성의 비만 및 혈중지질을 개선할 수 있을 것으로 기대된다. 불안장애 실험에서는 고흥산 석류 농축액 투여로 인해 불안장애가 개선되는 경향을 보였으나 통계적 유의성이 없었고, 이란산 시판 제품 투여 시에는 대조군에 비해 유의하게 개선시키는 것으로 나타났다. 우울증 또한 시판 제품 투여군에서는 대조군에 비해 유의하게 개선 효과를 나타내었으나 고흥산 석류 농축액 투여군에서는 우울증 개선 효과가 확인되지 않았다. 이상과 같은 결과를 통해 고흥산 석류 농축액은 난소를 적출한 rat의 골 소실을 현저히 개선하고 복부/내장지방 및 혈중지질을 농도 의존적으로 개선하여 골다공증, 비만 및 심혈관 질환과 같은 갱년기 증상에 효과가 있음을 확인하였다. 그러나 고흥산 석류 농축액 투여군에서 대표적인 갱년기 증상인 우울증과 불안장애 개선에 유의성 있는 효과가 나타나지 않는 것은 동물실험 모델에서 사람에게 나타나는 다양한 갱년기 증상을 모두 평가하기에 한계가 있는 바, 향후 추가적인 연구를 통해 고흥산 석류 농축액이 갱년기 여성에게 나타나는 여러 가지 증상 중 특정 증상에 대해 선택적으로 효과를 나타내는지에 대해 임상시험을 통해 검증할 필요가 있겠다.

• 여성건강간호학회지
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• 제5권2호
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• pp.230-246
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• 1999

The purpose of this study was to identify the degree of hardiness, knowledge of menopause, menopausal management of the middle aged women to identify the variables that show differences in the hardiness, knowledge of menopause and menopausal management of middle aged women and to investigate the relation ship among hardiness, menopausal knowledge and menopausal management of the middle aged women. The subjects were 132 middle-aged women and belonged to the age between 40 and 60. They were selected in Pusan, Korea. Data were collected from Oct. to Nov., 1998 by means of a structured questionnaire. The instruments used for this were the hardiness scale developed by Song In Sook and Song Ae Ri and the menopausal management scale developed by Song Ae Ri. The results were as follows 1. The mean score of hardiness was 2.83, in minimum score 1.24 tomaximun score 5.04. The mean score of knowledge of menopausal was 0.68, in minimum score 0.21 to maximum score 0.71. the mean score of menopausal management was 2.26, in minimum score 1.35 to maximum score 3.18. 2. In the relation between social demographic and hardiness there were significant differences in the health condition, income, supportive person. In relation between social demographic and menopausal knowledge there were significant differences in the health condition, family members. In the menopausal management there was significant differences in the marital state. 3. There was significant correlation between the hardiness and menopausal management of middle aged women (r=-0.208, p=0.017). 4. There was not significant correlation between the knowledge of menopause and menopausal management (r=0.001, p=0.992). These findings suggest the need to develop nursing strategy to improve the power of hardiness in middle aged women. hardiness is important to improve the menopausal management of middle aged women.

• 여성건강간호학회지
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• 제7권4호
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• pp.473-485
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• 2001

This cross-sectional design was to identify the age at menopause of Korean women and the levels of bothersome menopausal symptoms. In addition, examining relationships between the levels of bothersome menopausal symptoms and sociodemographic factors, body mass index, menopause-related factors, and life-style behavior factors including smoking, alcohol use, physical activity, and diet was done. Two thousand eight hundred seven naturally postmenopausal women aged between 41-65 years were recruited by self-selection from 7 metropolitans and 6 provinces in Korea from Dec. 20, 1998 to April 30, 1999. The age at menopause of Korean women was 49.2 years(mean) and 50.0 years (median). The menopausal age of Korean women has slightly increased compared to a previous study. Based on the demographic factors, residential area and socioeconomic status were associated with the bothersome levels of climacteric symptoms. In the case of the life-style behaviors analysis, only alcohol use and a preference for wheat were associated with the bothersome levels of climacteric symptoms, especially physical symptoms.

• 생명과학회지
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• 제33권3호
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• pp.252-259
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• 2023

노화에 따른 난소 기능 저하와 성호르몬 생성 감소는 호르몬 결핍을 유발하여 여성의 갱년기를 유발한다. 여성 갱년기 증상 개선을 목적으로 에스트로겐 유사 물질이 함유된 천연물을 연구하였다. 본 연구는 난소 적출술을 받은 쥐를 대상으로 Gastrodia elata Blume 추출물(TVB-1000)의 효능을 평가하였다. 난소 적출 수술을 한뒤 7일의 회복 기간 후 TVB-1000 처리군에게 16, 40, 100 mg/kg을 12주 동안 경구 투여하였다. OVX 양성 대조군에는 17β-estradiol을 10 ㎍/kg의 용량으로 쥐의 등 부위에 피하 주사하였다. 그 결과 TVB-1000 처리군에서 심혈관질환 지표인 TG와 LDL-C가 모든 농도에서 유의하게 감소했다. LDL-C/HDLC 비는 TVB-1000 투여군 중 Medium, High군에서 유의하게 감소하였다. 또한 TVB-1000 고농도 처리군에서 복부지방 무게가 통계적으로 유의하게 감소하였다. ER- α의 발현량은 저농도 및 중농도 투여군에서 통계적 유의성을 보이며 증가하였으나 ER-β는 유의한 변화를 보이지 않았다. 실험을 통해 TVB-1000은 에스트로겐 유사 효과로 인해 갱년기 증상 중 하나인 심혈관계 질환을 예방하는 기능성 식품 소재로써 유용할 수 있음을 보여준다.

• 여성건강간호학회지
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• 제11권1호
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• pp.12-19
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• 2005

Purpose: This study was to identify the correlations between management of menopause, urinary incontinence and sexual satisfaction in climacteric women. Method: This study was conducted using a convenient sampling method in and around Jinju city, and each participant gave consent for the research. A total sample of 250 middle-aged women aged 40 to 60 years were chosen for the study, of which 157 women completed the questionnaires used for the analysis. Data was collected from Jan 1st to Mar 31st, 2004 by structured questionnaires (questionnaires for management of menopause, urinary incontinence and sexual satisfaction). Result: The characteristic variables significantly related to management of menopause were occupation and religion. The characteristic variable significantly related to urinary incontinence was age. The characteristic variables significantly related to sexual satisfaction were religion, economic status, and frequency of delivery. The relationship between management of menopause and sexual satisfaction was statistically significant with a positive correlation. Conclusion: It is hoped that the above findings will stimulate health promoting programs for climacteric women.

• 한국보건간호학회지
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• 제17권2호
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• pp.224-237
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• 2003

Purpose : This study was designed to describe the relationship on climacteric symptom and health behavior according to hormone replacement therapy (HRT) in climacteric women. Method : Data were collected through self-reported questionaries which were constructed to include a climacteric symptom and health behaviors of climacteric women. The subjects for this study were 135 climacteric women between 45-65 years of age living in Kuri city. Among them. 65 were in the experimental group and the other 70 were in the control group. The data were analyzed by descriptive statistics, t-test, $x^2-test$, ANOVA, and Pearson Correlation Coefficient. Results : The results were as follows 1) There was no significant difference on the climacteric symptom between the group of women receiving HRT and those who did not (t=1.973, p=0.162). 2) The mean health behavior score for the group of women receiving HRT was significantly higher than those who did not(t=2.557, p=0.042). 3) The climacteric symptom and health behavior were positively correlated (r=.289, p=0.015) in women receiving HRT, while these were negatively correlated (r=-.242, p=0.043) in women without HRT. 4) Women in the HRT group showed higher climacteric symptom than the those In the control group in most items. 5) The mean score for health behavior was 2.76 in the hormone replacement therapy group and 2.35 for the control group. 6) For women in the experimental group, climacteric symptom was significantly different by the level of education (F=7.371, p=.001). 7) For women in the control group, climacteric symptom was significantly different by the number of children (F=2.873, p=.044), the level of education (F=5.616, p=.006), the number of abortion (F=3.231, p=.015), and the status of menstruation (F=4.129, p=.020). 8) For women in the experimental group, health behavior was significantly different by the level of education (F=7.351, p=.001), frequency of exercise (F=8.106, p=.000), and the status of menstruation (F=3.446, p=.032), 9) For women in the control group, health behavior was significantly different by frequency of the exercise (F=7.381, p=.001). Conclusion : This study results indicated that there was no association between the HRT and climacteric symptoms, while there was positive correlations between the HRT and health behavior. Therefore. it is assumed that HRT increases the positive health behavior of women.