• 건강소식
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• v.35 no.5
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• pp.16-17
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• 2011

건강검진에서 혈압, 혈당과 더불어 빠지지 않는 항목이 바로 간 수치다. 흔히 간 수치가 높다 낮다 등으로 표현하는데, 정확한 의미를 아는 사람은 많지 않다. 간 수차(간 효소 수치)는 간이 얼마나 튼튼한지를 나타내는 척도다. 이 같은 간 수치를 알아보는 간 기능 검사는 1차적으로는 소변을 받고 혈액을 뽑으면 된다. 따라서 검사 전 금식은 필수다. 만약 1차 검사에서 이상이 발견되면 2차 혈액 검사를 진행하거나 종양표지자, 복부초음파, CT, MRI, 복강경, 복부혈관조영 등 다양한 방법으로 심층적인 검시를 진행한다. 간은 2/3가 손상돼도 정상기능을 유지하는 반면, 기능을 상실하기 전까지 이렇다 할 증상이 없어 질환을 알아차리기가 쉽지 않다. 그래서 간을 '침묵의 장기'라는 고약한 별칭이 따라붙는 이유다. 간 기능 검사를 통해 수시로 점검하는 길만이 최선이다.

• Korean Journal of Psychosomatic Medicine
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• v.12 no.1
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• pp.23-29
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• 2004

The objective of this study was to make a comparison on anger level between patients with coronary artery diseases and healthy individuals. 233 patients with coronary artery diseases and 215 normal controls were enrolled in this study. The Anger Expression Scale, the anger and aggression subscales of the Stress Response Inventory(SRI) and the hostility subscale of the Symptom Checklist-90-revised(SCL-90-R) were used to assess the level of anger. The patients with coronary artery diseases scored significantly higher on the anger-out and anger total subscales of the anger expression scale, the anger and aggression subscales of the SRI than the normal controls. The patients with angina pectoris had significantly higher scores in the anger-out and anger-total subscale than those with myocardial infarction. Male subjects scored significantly higher on the anger-in subscale than females, whereas female subjects scored significantly higher on the anger-out subscale than male subjects. These results suggest that patients with coronary artery diseases are likely to have a higher level of anger or anger expression than normal controls and that there may be difference in anger expression between male and female patients. It is emphasized that anger management is needed to prevent the coronary artery disease patients from aggravating the illness.

• Journal of Periodontal and Implant Science
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• v.34 no.3
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• pp.671-681
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• 2004

Genomic Project 이후로 다양한 질환에 있어서 유전적인 영향에 관한 연구가 진행되고 있다. 이 연구의 목적은 한국인 치주질환 환자에서 Fc ${\gamma}R$ 유전자의 유전자다형성과 치주질환 특성과의 관련성을 알아보는 것이다. 치주적으로 건강한 한국인 90명(대조군, 남자64명, 여자26명), 중도 만성 치주염환자 40명(severe chronic periodontitis patients; severe CP, 남자 24명, 여자 16명)을 대상으로 임상지수(치주낭 깊이, 입상부착소실, 치은지수, 치태지수, 탐침 후 출혈지수, 치조골소실)를 측정하였다. 또한 이들의 정맥혈에서 추출한 DNA를 PCR(Polymerase Chain Reaction)법, 전기영동법 등을 이용하여 Fc ${\gamma}RIIIa$ , Fc ${\gamma}RIIIb$의 대립유전자의 존재여부를 확인하였다. 이를 바탕으로 각 유전자의 다형성 및 Fc ${\gamma}R$ 복합유전자형 (Fc ${\gamma}R$ composite genotype)을 확인하여, 각 군 간을 비교하였다. 치주질환의 특성과 유전자 다형성과의 관련성을 알아보기 위하여 Fc ${\gamma}R$ 유전자에 대한 유전자다형성을 조사한 결과 다음과 같은 결과를 얻을 수 있었다. 1. Fc ${\gamma}RIIla$에 대한 유전자다형성 연구결과 대조군과 severe CP, AgP군 사이에서, severe CP와 AgP군 사이에서는 대립유전자분포가 서로 유의성 있는 차이를 나타내었지만(p<0.05), Fc ${\gamma}RIIlb$에서는 유의성 있는 차이를 보이지 않았다(p>0.05). 2. Fc ${\gamma}R$ 복합유전자형간의 비교에서 유의성 있는 차이를 발견할 수 없었다(p>0.05). 이와 같은 결과를 종합하여 볼 때 실험대상 한국인 치주염환자에서 Fc ${\gamma}R$ 유전자에 대한 다형성분석에서 Fc ${\gamma}RIIIa$ 대립유전자가 치주염에 대한 감수성과 관련되어 있다고 생각된다. 이 연구의 결과는 유전자의 차이가 치주질환의 감수성 판단의 자료로 활용할 수 있는 가능성을 보여주고 있다.

• The Journal of the Convergence on Culture Technology
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• v.9 no.6
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• pp.85-96
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• 2023

In a reality where negative perceptions and social prejudices towards individuals with mental illnesses persist, the absence and lack of social support systems acquired through personal intimate social networks can be considered a significant hindrance to the quality of life for those with mental disorders. Therefore, this study examined the impact of the characteristics of social networks and social support on the life satisfaction of individuals with mental illnesses. A survey was conducted with 180 patients from seven mental health treatment facilities in the Daegu area. The data were analyzed using MANOVA, hierarchical multiple regression analysis, and Sobel test for mediation analysis with SPSS 25 software. The key findings of the study revealed that the intimacy aspect of social networks had a positive and significant effect on social support and life satisfaction. On the other hand, the size of the social network showed a negative influence on social support. Furthermore, social support partially mediated the relationship between the intimacy of social networks and life satisfaction, and it fully mediated the relationship between the size of social networks and life satisfaction. Based on these research outcomes, practical and policy-related recommendations are provided to enhance life satisfaction through increased social support for this population.

• The Journal of the Korea Contents Association
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• v.22 no.2
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• pp.782-793
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• 2022

The rise in chronic disease not only has a negative effect on people's lives, but it also increases the cost of medical care owing to the increased usage of medical care as health and medical technology improves, life expectancy rises, and rapid population ageing. In such context, this study examined the difference in the disease cost of hypertension according to demographic information and the effect of the initial diagnosis age and treatment period on the cost. This study used the Korean Health Panel Survey from 2010 to 2017, and selected subjects based on health insurance beneficiaries between the ages of 30 and under 80. With the selected data, the direct and indirect costs of disease loss were calculated according to the cost of illness approach, and we constructed a disease-loss ratio cohort considering the age of diagnosis and time of treatment for hypertension. From the results of the study, the annual cost of disease loss for hypertensive patients differed by gender by 110,107 won, and it was found that the cost increased by 1.8 times as the treatment time increased. In addition, when comparing disease loss ratios between the same age groups, it was found that the disease loss ratios between those in their 60s and 70s were affected by treatment time. This study confirmed that hypertension significantly affects the cost of the disease, and not only requires early diagnosis and management, but also preventive efforts to lower the incidence of hypertensive disease must be strengthened.

• Journal of the Korean Society for Aviation and Aeronautics
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• v.20 no.1
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• pp.34-38
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• 2012

호산구는 염증 반응에 의해 활성화되며, 주로 기생충 감염이나 알러지 질환 등에 대한 면역 작용을 담당한다고 알려져 있다. 호산구 증가증은 약물 반응, 알러지, 국소적인 기생충 감염 등에 의한 경우가 많지만, 자가면역성 질환이나 종양에 의한 경우도 있다. 최근 연구를 통해 위염의 대표적인 원인균 중 하나인 유문나선균 역시 위점막에서 나타나는 조직 호산구 증가증의 원인이 될 수 있다고 밝혀지고 있으나, 유문나선균에 의한 호산구 증가증 발생 기전이나 빈도는 아직까지 확립되지 않고 있다. 위점막 내 호산구 침윤과 동반되는 위염은 복통, 오심, 구토, 설사, 장폐색 등을 일으킬 뿐만 아니라, 아토피성 피부염, 천식, 위식도 역류, 염증성 장질환 등의 발생과 관련이 있다고 보고되고 있다. 위염 및 다양한 관련 질환에 의한 증상은 공중 근무자들의 임무 수행 능력을 저하시켜 항공기 사고를 발생시킬 수 있는 가능성을 가지고 있다는 점에서 항공의학적으로 매우 중요하며, 실제로 호산구성 위염이나 유문나선균 감염의 치료 여부가 공중 근무자에게 일시적 또는 영구적 비행임무정지를 부과할 수 있는 기준이 되기도 한다. 본 연구에서는 대한민국 공군 장병 환자를 대상으로 내시경을 통해 얻은 위점막 조직 내 호산구수를 측정하고, 이를 위점막 표면의 유문나선균 존재 유무와 관련지어 보았다. 111명 중 20명의 환자에서 한 고배율 시야 당 30개 이상의 호산구가 관찰되었고, 63명의 환자의 위점막 표면에서 유문나선균을 확인하였다. 또한 위점막 내 호산구의 밀도와 유문나선균의 존재 간의 관계는 통계학적으로 유의하였다. 본 연구의 결과는 대한민국 공군 장병을 대상으로 하여 조직 호산구 증가증과 유문나선균의 빈도 및 상호 관계를 최초로 분석했다는 점에서 의의가 있으며, 추후 유문나선균이 어떤 기전으로 위점막 조직 내 호산구의 증가에 관여하는지에 대한 연구를 진행하기 위한 기초 자료로서 활용될 수 있을 것이다.

• Journal of the Korea Convergence Society
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• v.8 no.8
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• pp.137-145
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• 2017

The purposed of this study was to identify cardiocerebrovascular disease risk assessment and the factors that affect cardiocerebrovascular disease risk. The subjects of this study were 1340 middle age women worker in one shipyard. This study was base on worker health check up data. Data were analyzed using SPSS18.0 program. "healthy group" were 1078(80.4%), "low risk group" were 45(3.4%), "moderate risk group" were 150(11.2%), "high risk group" were 67(5.0%). Age, HDL, LDL, smoking, family history of stroke, hypertension were the factors that affected the risk cardiocerebrovascular disease. Results of this study can be used as fundamental data for developing cardiocerebrovascular disease preventive program in middle aged women.

• Journal of Convergence for Information Technology
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• v.10 no.3
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• pp.151-162
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• 2020

This study was to find out the influence of smoking behavior in Korean adults on chronic diseases using data from the seventh Korea national health and nutrition examination survey(KNHANES VII-2) 2017. The subjects were 6,193. The data were analyzed by frequency analysis, x² test and logistic regression analysis using SPSS 25 complex samples Win program. The main findings were that smoking age and smoking behavior were considered as early as the age of smoking, and in case of smoking in the past, the prevalence of chronic disease increased 1.30 times and 2.75 times, respectively. When the subjects' health behaviors and demographic characteristics were simultaneously corrected, the higher the age was, the more they were 0.25 times higher and 0.34 times higher than the graduate level of education. As a result, it is necessary to improve lifestyles such as obesity and lack of exercise, to reduce the prevalence of chronic disease in Korean adults, and to pay attention to younger age groups. There is a need to develop interdisciplinary convergent approaches with great interest.

• Journal of Dental Rehabilitation and Applied Science
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• v.30 no.4
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• pp.329-338
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• 2014

Patients who lost molars from dental caries or periodontitis have difficulty in maintaining their vertical dimension because their incisors and premolars also show vertical tooth movement. Missing posterior molars leads to occlusal interference and collapse of occlusal plane due to extrusion of opposite teeth and tipping of adjacent teeth. When this condition persists over long time, mandible moves forward, so it causes mobility and labioversion of upper incisors. This progress cannot be stopped spontaneously and the situation gets worse and worse. Therefore, for a patient with pathologic teeth migration caused by chronic periodontitis, interdisciplinary approach which is including periodontal treatment, orthodontic teeth alignment and prosthetic restoration of missing molars is required. This case report shows successful multidisciplinary approach to a patient who lost vertical dimension due to severe dental caries and periodontitis.

• Korean Journal of Plant Resources
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• v.26 no.5
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• pp.652-657
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• 2013

In the present study, anti-oxidative and the RMC proliferation inhibitory propeties of 80% ethanol extracts from 63 kinds of traditional medicines were investigated. Inhibitory effects of RMC proliferation were showed that Dalbergia odorifera T. Chen., Melia azedarach Linn$\acute{e}$ and Hydnocarpus anthelmintica Pierre. Among them Hydnocarpus anthelmintica Pierre had the highest anti-oxidative activity ($ORAC_{PE\;value}=1.6$, DPPH = 81.1), but Dalbergia odorifera T. Chen. and Melia azedarach Linn$\acute{e}$ had no effects. These results suggest that the Hydnocarpus anthelmintica Pierre could prevent or protect from kidney disease as antioxidant and anti-proliferative agent for RMC.