• Journal of the Korean Society of Food Science and Nutrition
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• v.32 no.2
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• pp.256-262
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• 2003

In order to design and develop a product that can treat the fatty liver, natural complex food with all natural ingredients was developed and supplemented to rats with high fat diet to induce fatty liver. As a result, when the amount of natural complex food was increased in diet of subjects, the activities of the blood serum AST, ALT, ALP, 3-GT and LDH were decreased. The total protein concentration levels of the 30% and the 50% natural complex food groups did not show changes in respect to the control group, but the 100% natural complex food groups showed significant decrease (p<0.05). Likewise, the amount of blood serum albumin in the 30% and the 50% natural complex food groups did not show improvement, but the 100% natural complex food did showed significant changes (p<0.05). The amount of blood serum triglyceride decreased as the amount of natural complex food was increased. In order to investigate the appearances of the accumulated fat in the liver, the animals were dissected. Livers of the control group (no natural complex food) were appeared as a white color, which means serious fat accumulation. However, all the natural complex food groups (30,50 and 100% natural complex food) showed noticeable decrease of fat content. Even the histology showed that livers of the control group had expansion of the fat, but a11 the natural complex food groups had e decreased as the contents and continued to show destroyed fatty cells. By observing the biological numeric data, the physical appearance and the history of the fatty liver, it is highly expected that natural complex food is very effective in treating the liver damaged -by the to fat and the cholesterol.

• Journal of the Korean Society of Radiology
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• v.14 no.7
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• pp.1003-1011
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• 2020

This study aims to compare and evaluate the image differences between single and dual sources in applying a technique to reduce metal artifacts using dual energy CT. Discovery CT 256 (GE, USA) as a single source device and Somatom Definition Flash (Siemens Health Care, Forchheim, Germany) as a dual source device. The self-made phantom (pigs with medical titanium screws inserted) was quantitative and qualitatively evaluated under the same conditions by varying the dose under the same conditions using a dual energy CT. The evaluation method was compared by measuring SNR for metal artifacts (scattering, stripe) generated by metal inserts, divided around bones and around tissues. There was a difference in images in the method of reducing metal artifacts between single-source and dual-source devices. In a single source device, the linearized prosthesis by metal implantation showed a greater decrease than the image obtained from a double source device, and the surrounding tissue was well observed without interference from the artifact. In dual-source devices, scattering and stripe artifacts caused by metal inserts decreased more than on a single source device, and signals from adjacent tissues surrounding the metal implant were well observed without diminishing. If the examination is conducted separately between single source and dual source devices depending on whether the area to which the patient is intended to be viewed during the examination is adjacent to the metal insert or the total tissue surrounding the metal insert, it is believed that diagnostic helpful images can be obtained.

• Clinical and Experimental Pediatrics
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• v.52 no.11
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• pp.1279-1282
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• 2009

Hepatomegaly and liver dysfunction might develop in patients with diabetes mellitus due to glycogen deposition or nonalcoholic steatohepatitis. We experienced a case of hepatic glycogenosis in a patient with type 1 diabetes mellitus who presented with recurrent hypoglycemia, suggesting impairment of glycogenolysis and gluconeogenesis. A 10-year-old girl with a 4-year history of type 1 diabetes mellitus was admitted because of recurrent hypoglycemia and abdominal pain in the right upper quadrant. She had Cushingoid features and hepatomegaly that extended 6 cm below the right costal margin. Laboratory data and radiologic examination revealed elevated liver enzyme levels due to fatty liver. Periodic acid-Schiff (PAS) staining revealed intense glycogen deposition in the cytoplasm of the hepatocytes and PAS reactivity was lost with diastase treatment. At 2 months after administration of glucagon injection and uncooked cornstarch between meals and at bedtime, the hypoglycemic episodes and liver dysfunction improved. It is important to distinguish hepatic glycogenosis from steatohepatitis, because it is possible to prevent excessive hepatic glycogen storage in hepatic glycogenosis cases by strictly controlling blood glucose level and by glucagon administration. To prevent severe hypoglycemic symptoms accompanied by hepatic glycogenosis, we suggest that uncooked cornstarch, which is effective in maintaining blood glucose level, can also be administered.

• Journal of the Korean Society of Food Science and Nutrition
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• v.38 no.9
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• pp.1153-1160
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• 2009

Monascus-fermented Korean red ginseng (MFRG), fermented by Monascus purpureus KCCM 12002, may be an ideal candidate for the hepatoprotectic, hypolipidemic and antioxidative activities. Effect of MFRG powder on these parameters in rats was investigated. Body weight gain, food intake, and water consumption were not significantly different among the groups. Total and relative weights of liver were significantly higher in MFRG group than that in other groups. The activities of AST and $\gamma$-GTP were highly lowered in MFRG group compared to control group. Contents of serum total lipid and triglyceride were significantly lowered in silymarin group and were significantly increased in MFRG group compared to control group, but tended to be lowered in RG group. Serum content of total cholesterol tended to be lowered in silymarin, RG, and MFRG groups compared to control group. HDL-cholesterol contents was only significantly increased in MFRG group compared to control group. At the same time, atherogenic index (AI) was also significantly lowered in silymarin, RG and MFRG groups compared to control group, and this effect was more pronounced in MFRG group. Content of thiobarbituric acid reactive substances (TBARS) in the liver was significantly lowered in MFRG group and tended to lowered in silymarin and RG groups compared to control group. The hepatic glutathione concentration was significantly higher in silymarin and MFRG groups. Hepatic morphology in all experimental groups revealed clear-cut hepatic lobules with the uniform pattern of the polyhedral hepatocytes radiating towards the periphery from the central vein. These results suggested that MFRG may have anti-atherogenic index (AI) and antioxidative activity in normal dietary feeding rats.

• Proceedings of the Korean Society of Veterinary Pathology Conference
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• 2002.11a
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• pp.137-137
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• 2002

개 유방 종양은 개에서 가장 흔한 종양들이지만 유방 분비물을 통한 세포학 진단의 의의는 크다. 이들 종양의 진단상 병리조직학적 진단은 보편화되어 있으며 그 정확성도 매우 높다. 그러나 진단에 걸리는 시간과 비용 문제를 간과 할 수는 없다. 본 증례는 전남대학교 부속동물병원에 내원한 9살된 암컷 요크셔테리어 종으로서 유선에서 혈액과 고름이 섞인 분비물이 5개월 동안 관찰되었다. 이들 분비물을 슬라이드에 도말하여 diff-quik 염색후 세포학적 진단결과 다양한 형태의 종양세포, 적혈구 및 호중구가 관찰되었다. 종양세포는 대소부동한 다형태성의 핵을 가지고 있었고, 핵소체는 뚜렷하였으며 핵과 세포질 비율(N/C) 도 매우 높았다. 전형적인 유방 선암종(adenocarcinoma) 세포로 진단되었으며 유방절제후 병리조직학적 검사 소견도 세포학적 진단과 일치하였다. 유방 선암종 분비물의 세포학적 진단은 보다 간편하고 적은 비용으로 진단해 낼 수 있었다. 개 유방 선암종 분비물의 세포학적 진단은 국내보고를 쉽게 찾을 수 없었다.

• Korean journal of food and cookery science
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• v.22 no.1 s.91
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• pp.62-68
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• 2006

This study evaluated the effect of the substitution of flour with Angelica plant(Bakluncho) powder on the characteristics of batter cake and cookies. The specific volume of batter cake was increased significantly with increasing content of Angelica plant powder, but hardness was decreased slightly. The specific volume of cookies didn't show significant difference, and the width detennined by the water content in the dough was decreased with increasing content of Angelica plant powder. The L value in the crust and crumbs of the cake was significantly the largest value in the control group. The a and b values were the highest in the 5% substituted sample group. The L, a and b values of the cookies also showed the same pattern. According to the sensory evaluation of cakes and cookies, the scores of flavor, color, and texture were raised by the addition of Angelica plant powder. The acceptance tests of cakes and cookies showed a higher overall acceptability than those of the 1% and 3% substituted samples.

• Journal of the Korean Society for Nondestructive Testing
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• v.28 no.2
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• pp.101-111
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• 2008

Strain imaging in a medical ultrasound imaging system can differentiate the cancer or tumor in a lesion that is stiffer than the surrounding tissue. In this paper, a strain imaging technique using quasistatic compression is implemented that estimates the displacement between pre- and postcompression ultrasound echoes and obtains strain by differentiating it in the spatial direction. Displacements are computed from the phase difference of complex baseband signals obtained using their autocorrelation, and errors associated with converting the phase difference into time or distance are compensated for by taking into the center frequency variation. Also, to reduce the effect of operator's hand motion, the displacements of all scanlines are normalized with the result that satisfactory strain image quality has been obtained. These techniques have been incorporated into implementing a medical ultrasound strain imaging system that operates in real time.

• KIISE Transactions on Computing Practices
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• v.21 no.6
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• pp.393-402
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• 2015

Human resources are one of the most essential elements of an organization. In particular, the more closed a group is, the higher the value each member has. Previous studies have focused on personal attributes of individual, such as medical history, and have depended upon self-diagnosis to manage structures. However, this method has weak points, such as the timeconsuming process required, the potential for concealment, and non-disclosure of participants' mental states, as this method depends on self-diagnosis through extensive questionnaires or interviews, which is solved in an interactive way. It also suffers from another problem in that relations among people are difficult to express. In this paper, we propose a multi-faced diagnosis model based on social network analysis which overcomes former weaknesses. Our approach has the following steps : First, we reveal the states of those in a social network through 9 questions. Next, we diagnose the social network to find out specific individuals such as victims or leaders using the proposed algorithm. Experimental results demonstrated our model achieved 0.62 precision rate and identified specific people who are not revealed by the existing methods.

• Journal of the Korean Society of Food Science and Nutrition
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• v.44 no.9
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• pp.1286-1294
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• 2015

The acute and subchronic toxicity of 1 kGy gamma-irradiated orange was evaluated in ICR mice. For acute toxicity, groups of 30 male and 30 female ICR mice were orally administered 1 kGy gamma-irradiated orange (0, 1,000, and 2,000 mg/kg). The mortality, clinical sign, body weight changes, and necropsy findings of ICR mice were observed for 14 days. No significant changes in body weight or abnormal gross findings were observed in relation to 1 kGy gamma-irradiated orange. Hematological and serum biochemical parameters were within normal ranges. According to the results, 1 kGy gamma-irradiated orange had no special toxic effects in male and female ICR mice at 2,000 mg/kg. For subchronic toxicity, groups of 36 male and 36 female ICR mice were given a diet of 1 kGy gamma-irradiated orange for 13 weeks (control, non-irradiated, and irradiated imported orange). During the experimental period, mortality, clinical signs, body weight change, food consumption, organ weight, and histopathological examination did not show any changes in comparison to the control group. Several hematological and serum biochemical parameters showed statistically significant changes, but these changes were within normal range. These results indicate that 1 kGy gamma-irradiated orange did not cause any toxic effects in male and female ICR mice and therefore can be considered as safe.

• KIPS Transactions on Software and Data Engineering
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• v.6 no.10
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• pp.493-498
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• 2017

Capsule endoscopy is specialized for the observation of small intestine that is difficult to access by general endoscopy. The diagnostic procedure through capsule endoscopy consists of three stages: examination of indicant, endoscopy, and diagnosis. At this time, key information needed for diagnosis includes indicant, lesions, and suspected disease information. In this paper, these information are defined as semantic features and the extracting process is defined as semantic-based analysis. It is performed in whole capsule endoscopy. First, several symptoms of patient are checked before capsule endoscopy to get some information on suspected disease. Next, capsule endoscopy is performed by checking the suspected diseases. Finally, diagnosis is concluded by using supporting information. At this time, some association are used to conclude diagnosis. For example, there are the disease association between the symptom and the disease to identify the expected disease, and the anatomical association between the location of the lesion and supporting information. However, existing knowledge models such as MST and CEST only lists the simple term related to endoscopy and cannot consider such semantic associations. Therefore, in this paper, we propose association-based knowledge model for supporting diagnosis of capsule endoscopy. The proposed model is divided into two; a disease model and anatomical model of small intestine, interesting area(organs) of capsule endoscopy. It can effectively support diagnosis by providing key information for capsule endoscopy.