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http://dx.doi.org/10.3746/jkfn.2003.32.2.256

Effects of Natural Complex Food on Specific Enzymes of Serum and Liver and Liver Microstructure of Rats Fed a High Fat Diet  

Lee, Eun (College of Life Science and Natural Resources, Sang-Ji University)
Kim, Wan-Jae (College of Life Science and Natural Resources, Sang-Ji University)
Lee, Young-Joo (College of Life Science and Natural Resources, Sang-Ji University)
Lee, Mi-Kyung (GMF Corporation)
Kim, Pan-Gu (GMF Corporation)
Park, Yeon-Jung (GMF Corporation)
Kim, Soo-Kyung (GMF Corporation)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.32, no.2, 2003 , pp. 256-262 More about this Journal
Abstract
In order to design and develop a product that can treat the fatty liver, natural complex food with all natural ingredients was developed and supplemented to rats with high fat diet to induce fatty liver. As a result, when the amount of natural complex food was increased in diet of subjects, the activities of the blood serum AST, ALT, ALP, 3-GT and LDH were decreased. The total protein concentration levels of the 30% and the 50% natural complex food groups did not show changes in respect to the control group, but the 100% natural complex food groups showed significant decrease (p<0.05). Likewise, the amount of blood serum albumin in the 30% and the 50% natural complex food groups did not show improvement, but the 100% natural complex food did showed significant changes (p<0.05). The amount of blood serum triglyceride decreased as the amount of natural complex food was increased. In order to investigate the appearances of the accumulated fat in the liver, the animals were dissected. Livers of the control group (no natural complex food) were appeared as a white color, which means serious fat accumulation. However, all the natural complex food groups (30,50 and 100% natural complex food) showed noticeable decrease of fat content. Even the histology showed that livers of the control group had expansion of the fat, but a11 the natural complex food groups had e decreased as the contents and continued to show destroyed fatty cells. By observing the biological numeric data, the physical appearance and the history of the fatty liver, it is highly expected that natural complex food is very effective in treating the liver damaged -by the to fat and the cholesterol.
Keywords
natural complex food; high fat-induced fatty liver; liver tissue; rats, microstrurture;
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