• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.11
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• pp.5350-5355
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• 2012

Human tyrosinase (hTyr) catalyzes the first and rate limiting step in the biosynthesis of a skin color determinant, melanin. Although a number of cosmetic companies have tried to develop hTyr inhibitors for several decades, absence of 3D structure of hTyr make it impossible to design or screen inhibitors by structure-based approach. Therefore, we built a 3D structure by comparative modeling technique based on the crystal structure of tyrosinase from Bacillus megaterium to provide structural information and to search new hit compounds from database. Our model revealed that two copper atoms of active site located deep inside and were coordinated with six strictly conserved histidine residues coming from four-helix-bundle. Substrate binding site had narrow funnel like shape and its entrance was wide and exposed to solvent. In addition, hTyr-tyrosine and hTyr-kojic acid, a well-known inhibitor, complexes were modeled with the guide of solvent accessible surface generated by in-house software. Our model demonstrated that only phenol group or its analogs could fill the binding site near the nuclear copper center, because inside of binding site had narrow shape relatively. In conclusion, the results of this study may provide helpful information for designing and screening new anti-melanogenic agents.

• Spatial Information Research
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• v.20 no.2
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• pp.155-164
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• 2012

Indoor fire simulators have been used to analyse building safety in the events of emergency evacuation. These applications are primarily focused on simulating evacuation behaviors for the purpose of checking building structural problems in normal time rather than in real time situations. Therefore, they have limitations in handling real-time evacuation events with the following reasons. First, the existing models mostly experiment the artificial situations using randomly generated evacuees while real world requires actual data. Second, they take too long time in operation to generate real time data. Third, they do not produce optimal results to be used in rescueing or evacuation guidance. In order to solve these limitations, we suggest a method to build an evacuation simulation system that can be used in real-world emergency situations. The system performs numerous simulations in advance according to varying distributions of occupants. Then the resulting data are stored in DBMS. The actual person data captured in infrared sensor network are compared with the simulation data in DBMS and the querried data most closely is provided to the user. The developed system is tested using a campus building and the suggested processes are illustrated.

• Journal of the Korea Society of Computer and Information
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• v.25 no.3
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• pp.243-250
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• 2020

In this paper, we propose an effective software education scheme for universities. The key idea of this software education scheme is to analyze software curriculum of QS world university rankings Top 10, SW-oriented university, and regional main national university. And based on the results, we propose five improvements for the effective SW education method of universities. The first is to enhance the adaptability of the industry by developing courses based on the SW developer's job analysis in the curriculum development process. Second, it is necessary to strengthen the curriculum of the 4th industrial revolution core technologies(cloud computing, big data, virtual/augmented reality, Internet of things, etc.) and integrate them with various fields such as medical, bio, sensor, human, and cognitive science. Third, programming language education should be included in software convergence course after basic syntax education to implement projects in various fields. In addition, the curriculum for developing system programming developers and back-end developers should be strengthened rather than application program developers. Fourth, it offers opportunities to participate in industrial projects by reinforcing courses such as capstone design and comprehensive design, which enables product-based self-directed learning. Fifth, it is necessary to develop university-specific curriculum based on local industry by reinforcing internship or industry-academic program that can acquire skills in local industry field.

• Journal of Korea Water Resources Association
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• v.50 no.4
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• pp.223-232
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• 2017

The ability to defend against floods in urban areas was weakened, because the increase in the impervious rate of urban areas due to urbanization and industrialization and the increase in the localized torrential rainfall due to abnormal climate. In order to reduce flood damage in urban areas, various runoff reduction facilities such as detention ponds and infiltration facilities were installed. However, in the case of domestic metropolitan cities, it is difficult to secure land for the installation of storm water reduction facilities and secure the budget for improving the aged pipelines. Therefore, it is necessary to design a storage system (called the detention pond in trunk sewer) that linked the existing drainage system to improve the flood control capacity of the urban area and reduce the budget. In this study, to analyze the effect of reducing runoff amounts according to the volume of the detention pond in trunk sewer, three kinds of virtual watershed (longitudinal, middle, concentration shape) were assumed and the detention pond in trunk sewer was installed at an arbitrary location in the watershed. The volume of the detention pond in trunk sewer was set to 6 cases ($1,000m^3$, $3,000m^3$, $5,000m^3$, $10,000m^3$, $20,000m^3$, $30,000m^3$), and the installation location of the detention pond in trunk sewer was varied to 20%, 40%, 60%, and 80% of the detention pond upstream area to the total watershed area (DUAR). Also, using the results of this study, a graph of the relationship and relational equation between the volume of the detention pond in trunk sewer and the installation location is presented.

• Proceedings of the Korean Society for Agricultural Machinery Conference
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• 2017.04a
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• pp.18-18
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• 2017

ISO11783은 농업 산업분야 통신 프로토콜의 국제 표준으로, 농용트랙터 및 작업기 ECU 간의 통신 프로토콜을 표준화한다. 이 표준은 서로 다른 제조사의 제품 간에 호환성을 갖게 하며, 정밀 농업에 대한 핵심 기반을 제공한다. 현재 해외에서는 이미 ISO11783 기반의 AFS(Advanced Farming System)를 통한 정밀농업이 상용화되어 농가에 보급되고 있다. 이에 비해, 국내에서 이러한 표준을 따르는 농기계들은 미비한 실정이며, 향후 농업의 정밀 농업화를 통한 고부가가치 창출 및 선진국의 무역 장벽에 대비와 해외 수출 판로 개척을 위해 ISO11783 표준에 대한 R&D가 필요로 한다. 이에 IsoAgLib를 분석하고 임베디드 보드에 Porting하여 ISO11783 기반 작업기 ECU를 구현하였고, 이를 기반으로 ISO11783 기반 작업기 ECU의 구현 방법을 발표한다. IsoAgLib의 시스템 아키텍처는 계층화 되어 있어, 타겟에 의존적인 계층만 수정하여, IAR 환경에서 Cortex M3 보드에 포팅을 완료하였다. 작업기 ECU들은 자신만의 인터페이스 화면을 갖으며, 이를 Object pool이라 한다. 이것을 Virtual Terminal(VT)에 업로드 하여, VT가 해당 작업기 ECU의 사용자 인터페이스 기능을 제공하도록 한다. 이에 작업기 ECU 구현 1 단계로, 'VT-Designer'를 통하여 Object pool를 설계한다. 2 단계, 'vt2iso'를 통해서 Object pool을 IsoAgLib 상에서 사용할 수 있도록 변환한다. 3 단계, 포팅된 IsoAgLib project에 변환된 파일을 포함 시킨다. 4 단계, 작업기 ECU의 주기적인 작업 및 각 메시지 수신시 수행할 작업을 코딩한다. 5 단계, 빌드 및 타겟 보드에 업로딩 한 후, New Holland 사의 $Intelliview^{TM}$ iv display (VT)과 연결하여 동작을 확인한다. 확인 결과로 VT에 디자인한 Object pool이 표시 되며 soft key 입력 시 작업기 ECU에서 LED가 변한다. 결론적으로, 연구 결과를 바탕으로 ISO11783 기반의 작업기 ECU의 디자인 및 구현이 가능하며, 이를 통해 향후 국내의 ISO11783 기반의 작업기 ECU의 개발에 도움을 줄 수 있다.

• Journal of the Korean Institute of Intelligent Systems
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• v.25 no.3
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• pp.279-286
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• 2015

The rapid increase of the current marine accidents is mainly due to the human execution errors. In an effort to address this, various kinds of researches such as construction of the digital vessels and vessel information monitoring systems have been conducted. But for safe navigation of vessels, it lack on systems study which can efficiently store, utilize and manage the mass data accepted by the vessel. In this paper, we propose a VWS(Virtual World System) that is based on the architecture of intelligent systems RVC(Reactive Layer-Virtual World-Considerative Layer) model of intelligent autonomous navigation system. VWS is responsible to store all the necessary information for safe navigation of the vessel and the information services to the sub-system of intelligent autonomous navigation system. VWS uses topology database to express the specific problem area, and utilizes a scheduling to reflect the characteristics of the real-time processing environment. Also, Virtual World defines API for the system to reflect the characteristics of the distributed processing environment. As a case study, the VWS is applied to a intelligent ship autonomous navigation system, and simulation is done to prove the effectiveness of the proposed system.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.8 no.1
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• pp.127-140
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• 1988

The management of sewage and rainfall runoff becomes an emerging problem with the growth of urban communities. From the uncontrollable excess intensity or amount of rainfall, the conditions of sewer surcharge or manhole overflow could be generated in the combined sewer network where municipal or industrial wastewaters and rainfall runoff flow. The predictive model far the prevention of property and human life losses from this inundation was studied in this research. In the development of a mathematical flow model for the combined sewer surcharge and overflow, the Preissmann Slot concept and the four-point implicit method of finite difference were utilized. For the usage in personal computer, the overlapping segment method that required less memory storage was adopted. Through the simulation of hypothetical sewer network, the conservation of discharge volume was checked, and the usefulness of the Preissmann Slot was assured from the temporal distribution of discharge and depth along the sewer network. Also the possible field application for the correction of sewer diameters and slopes in the design of sewer network which has no surcharge/overflow condition was suggested.

• Korean Journal of Applied Biomechanics
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• v.12 no.2
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• pp.307-318
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• 2002

To provide a guideline for the development of a web-based sport biomechanics class in undergraduate program, thirty web sites, searched via search engines in May 2002, were analyzed intensively. In terms of requirement of log-in, only one site of 30 sites required user name and password. Seventeen(57%) sites provided the lecture note, which had various file formats such as 59% if PDF, 29% of HTML, and 12% of PPT. Fourteen(47%) sites provided the assignment and grade information on web. Eleven(37%) sites provided various resource and links which were related in sports biomechanics. Only four(13%) sites provided discussion or online digitizing or kinematic analysis program. Based on above results, a guideline for the development of a virtual classroom for college level sport biomechanics. A web-based sport biomechanics class should be developed with consideration of several functions as follows; homepage design, lecture note, measurement of class attendance, collaborative research system, and web-based data collection and analysis software for biomechanics laboratory.

• Proceedings of the Korea Water Resources Association Conference
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• 2005.05b
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• pp.1068-1072
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• 2005

조석이란, 해면의 완만한 주기적 승강을 말하며, 보통 그 승강은 1일 약 2회이나, 곳에 따라서는 1일 1회의 곳도 있다. 조석에 있어서는 이 밖에 수일의 주기를 갖는 약간 불규칙한 승강, 반년, 또는 1년을 주기로 하는 다소 규칙적인 승강까지 포함하여 취급한다. 그러나, 각 항만마다 갖는 특정적인 주기인 수분내지 수십분의 주기의 승강은 조석으로 취급하지 않는다. 조석은 해양의 제현상 중에서 예측가능성이 가장 큰 현장으로 이는 조석이 천체의 운행과 연관되기 때문이다. 조석이란 지구로부터 일정한 거리에서 각 고유의 속도를 가지는 적도상을 운행하는 무수의 가상천체에 기인하는 규칙적인 개개의 조석을 합성한 것이며 이 개개의 조석을 분조(Constituent)라 한다. 여기에서 사용되는 신경망 모형은 입력과 출력으로 구성되는 블랙박스 모형으로서 하나의 시스템을 병렬적으로 비선형적으로 구축할 수 있다는 장점 때문에 과거 하천유역의 강우-유출과정에서의 경우 유출현상을 해석하고 유출과정을 모형화 하기 위해 사용하였다. 본 연구에서는 기존의 조위 예측방법인 조화분석법이 아닌 인공신경망을 이용하여 조위예측을 실시하였다. 학습이라는 최적화 과정을 통해 구조와 기능이 복잡한 자연현상을 그대로 받아들여 축적시킴으로써 이를 지식으로 현상에 대한 재현능력이 뛰어나고, 또한 신경회로망의 연상기억능력에 적용하여 수학적으로 표현이 불가능한 불확실한 조위곡선에 적용하기에 유리한 장점을 가지고 있다. 본 연구의 목적은 과거 조위이론을 통해 이루었던 조위예측을 우리가 알기 쉬운 여러 기후인자(해면기압, 풍향, 풍속, 음력 등)에 따른 조위곡선을 예측하기 위해 신경망 모형을 이용하여 여수지역의 조위에 적용하여 비교 분석하고자 한다. May가 제안한 공식을 더 확장하여 적용할 수 있는 실험 공식으로 개선하였으며 다양한 조건에 대한 실험을 수행하여 보다 정밀한 공식으로 개선할 수 있었다.$10,924m^3/s$ 및 $10,075m^3/s$로서 실험 I의 $2,757m^3/s$에 비해 통수능이 많이 개선되었음을 알 수 있다.함을 알 수 있다. 상수관로 설계 기준에서는 관로내 수압을 $1.5\~4.0kg/cm^2$으로 나타내고 있는데 $6kg/cm^2$보다 과수압을 나타내는 경우가 $100\%$로 밸브를 개방하였을 때보다 $60\%,\;80\%$ 개방하였을 때가 더 빈번히 발생하고 있으므로 대상지역의 밸브 개폐는 $100\%$ 개방하는 것이 선계기준에 적합한 것으로 나타났다. 밸브 개폐에 따른 수압 변화를 모의한 결과 밸브 개폐도를 적절히 유지하여 필요수량의 확보 및 누수방지대책에 활용할 수 있을 것으로 판단된다.8R(mm)(r^2=0.84)$로 지수적으로 증가하는 경향을 나타내었다. 유거수량은 토성별로 양토를 1.0으로 기준할 때 사양토가 0.86으로 가장 작았고, 식양토 1.09, 식토 1.15로 평가되어 침투수에 비해 토성별 차이가 크게 나타났다. 이는 토성이 세립질일 수록 유거수의 저항이 작기 때문으로 생각된다. 경사에 따라서는 경사도가 증가할수록 증가하였으며 $10\% 경사일 때를 기준으로 $Ro(mm)=Ro_{10}{\times}0.797{\times}e^{-0.021s(\%)}$로 나타났다.천성 승모판 폐쇄 부전등을 초래하는 심각한 선

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.13 no.2
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• pp.129-137
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• 2020

Currently, The autonomous vehicle market is researching and developing four-level autonomous vehicles beyond the commercialization of three-level autonomous vehicles. Because unlike the level 3, the level 4 autonomous vehicle has to deal with an emergency directly, the most important aspect of a four-level autonomous vehicle is its stability. In this paper, we propose an Optimized Vehicle Routing System (OVRS) that determines the route with the lowest probability of an accident at the destination of the vehicle rather than an immediate response in an emergency. The OVRS analyzes road and surrounding vehicle information collected by The RSU communication to predict road hazards, and sets the route for the safer and faster road. The OVRS can improve the stability of the vehicle by executing the route guidance according to the road situation through the RSU on the road like the network routing method. As a result, the RPNN of the ASICM, one of the OVRS modules, was about 17% better than the CNN and 40% better than the LSTM. However, because the study was conducted in a virtual environment using a PC, the possibility of accident of the VPDM was not actually verified. Therefore, in the future, experiments with high accuracy on VPDM due to the collection of accident data and actual roads should be conducted in real vehicles and RSUs.