• Title/Summary/Keyword: 가돌리늄

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Synthesis of (Gd0.74Y0.11Tb0.15P1.15)OδPhosphors Using Combinatorial Chemistry (조합화학을 이용한 (Gd0.74Y0.11Tb0.15P1.15)Oδ 형광체 합성 및 발광특성)

  • 이재문;유정곤;박덕현;김지식;손기선
    • Journal of the Korean Ceramic Society
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    • v.41 no.5
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    • pp.381-387
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    • 2004
  • Recently developed Plasma Display Panels (PDP) require phosphors of high luminance at Vacuum Ultraviolet (VUV) excitation. The present investigation developed new PDP phosphors using combinatorial chemistry method. We applied T $b^{3+}$ -activated yttrium gadolinium phosphates system to our combinatorial fine-tuning technique. As a result, the optimum composition was determined to be (G $d_{0.74}$ $Y_{0.11}$T $b_{0.15}$) $P_{1.15}$ $O_{\delta}$ through the two-step combinatorial screening process including excess phosphorous and Gd replacement. We found that the sample of the optimum composition shows a higher luminescence efficiency at VUV excitation and a shorter decay time than the commercially available Z $n_2$ $SiO_4$:Mn phosphor.

Quantitative Comparison of 1H-MRS Spectra Depending on the Paramagnetic Gadolinium Contrast Agent(GBCA) Injection (가돌리늄 조영제 주입에 따른 1H-MRS spectrum의 정량적 비교)

  • Choi, Kwan-Woo;Son, Soon-Yong;Yoo, Beong-Gyu
    • Journal of the Korean Society of Radiology
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    • v.11 no.7
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    • pp.589-595
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    • 2017
  • This study evaluated the effect of gadolinium contrast agents on the spectrum of metabolites during $^1H-MRS$ of brain and to investigate whether the contrast agents injected before MR spectroscopy significantly affect the estimated peaks of MRS. From January to May 2017, brain MR spectroscopy was performed on 30 patients to compare the spectrum before and after contrast injection of the brain white matter tissue. As a result, the spectrum of metabolites decreased after the paramagnetic contrast agents injected. However, it was not statistically significant which indicated that the use of contrast agent did not meaningfully affect the spectrum of metabolites. In conclusion, the use of the paramagnetic contrast before the acquisition of the spectroscopy may aid voxel positioning especially when it is difficult to determine the exact location of the lesion or the contrast is low.

A Case Report of Vestibular Schwannoma Misdiagnosed as Idiopathic Sudden Sensorineural Hearing Loss (특발성 돌발성 난청으로 오인된 청신경 종양 1례)

  • Ko, Hye-Yeon;Kim, Jae-Ho;Lee, Ma-Eum;Kim, Min-Hee
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.34 no.3
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    • pp.80-91
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    • 2021
  • Objective : The purpose of this study is to discriminate the vestibular schwannoma misdiagnosed as Idiopathic Sudden Sensorineural Hearing Loss. Methods : A 46-year-old female patient who was suffering left sudden sensorineural hearing loss(SSNHL), visited after diagnosed as Idiopathic SSNHL by previous hospital. For diagnosing the vestibular schwannoma, we conducted the Puretone audiometry, auditory brainstem response threshold test and magnetic resonance imaging(MRI) for temporal bone with enhancement. Result : Auditory Brainstem Response threshold test was abnormal and in enhanced MRI, the vestibular schwannoma in left side was detected. The patient was discharged from the hospital for tertiary hospital care. Conclusions : When the patient with SSNHL visits a hospital even if after diagnosed as Idiopathic SSNHL by previous hospital, a doctor should keep in mind the possibility of vestibular schwannoma.

Effects of Gadolinium Contrast agent on Bone Mineral Density Measurement using Dual Energy X-ray Absorptiometry (가돌리늄조영제가 이중에너지 X-선 흡수법을 이용한 골밀도검사에 미치는 영향)

  • Lee, Keun-Ohk;Lee, Min-Su
    • Journal of the Korean Society of Radiology
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    • v.15 no.1
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    • pp.63-70
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    • 2021
  • Radiographic contrast agents are used for diagnostic purposes and are one of the factors affecting measured values in bone density tests. They are absorbed into tissues and have an effect of increasing the measured values of bone density, so they are avoided as much as possible before performing a bone density test. MRI contrast agents, which have different physical properties and mechanisms of action than radiographic contrast agents, are based on gadolinium, a metal element. They have radiopacity characteristics, so MRI are generally performed prior to examination using radiation. The purpose of this study was to investigate the effects of MRI contrast agents on bone mineral density examination using dual energy X-ray absorption. Two types of gadolinium based MRI contrast agents were injected into an acrylic water tank for each volume, and the humanoid spine phantom was inserted and the BMD and T-score from (L1-L4) were analyzed by scanning a total of 30 times, 5 times for each injection type. The average value of the measured total (L1-L4) bone density for each of the two contrast agents was 0.952±0.052, 0.957±0.050, and 0.956±0.05g/㎠, respectively, for the Gadoterate Meglumine component 0mL, 7.5mL and 15mL, when the gadobutrol components were 0mL, 5mL, and 10mL, there was no statistically significant difference at all sites at 0.953±0.001, 0.954±0.001, and 0.945±0.001g/㎠, respectively(p>0.05). The average value of total T-score was -0.46±0.05, -0.4±0, -0.42±0.04 when the Gadoterate Meglumine component was 0mL, 7.5mL and 15mL, respectively. When the Gadobutrol ingredients were 0mL, 5mL and 10mL, there was no statistically significant difference in all areas, with -0.46±0.05, -0.46±0.05, and 0.5±0.00, respectively. In this experiment, the MRI contrast agent was found to have no effect on bone density tests, using the dual-energy X-ray absorption method. There is a limitation in that physical conditions such as kidney and health conditions etc. were not taken into consideration, so further clinical research is expected to be conducted in the future.

Preparation of Spherical Gadolinium Compound Particles (구형 가돌리늄화합물 입자 제조)

  • 김응호;최청송;정경채;박진호;장인순
    • Journal of the Korean Ceramic Society
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    • v.30 no.7
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    • pp.563-570
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    • 1993
  • Spherical, monosized gadolinium compound was prepared by the reaction of Gd(NO3)3 solution with decomposition products of urea in the solution at evaluated temperature. Chemical composition and calcination characteristics of spherical gadolinium compound prepared were investigated by X-ray IR and TG-DTA. The approximate chemical composition of the spherical particle precipitated was Gd(OH)CO3.1.5H2O. Gd(OH)CO3.1.5H2O was calcined to monoclinic type Gd2O3 at 115$0^{\circ}C$ via cubic type Gd2O3 near $600^{\circ}C$. The effects of various parameters such as pH, temperature, concentration ratio of urea to gadolinium precusor, ageing time, and others material (CCl3COOH and HOCNH2) in stead of urea as precipitating agent on the properties of the resulting precipitates were studied systematically.

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Extraction characteristics of extraction resins containing HEH/EHP (HEH/EHP를 함유(含有)한 추출(抽出)수지의 추출특성(抽出特性))

  • Park, Kye-Sung;Kim, Joon-Soo
    • Resources Recycling
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    • v.15 no.4 s.72
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    • pp.13-18
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    • 2006
  • This study was to investigate the extraction characteristics of extraction resins containing HEH/EHP for Gadolinium solution. The experiments were carried out with the variation of equilibrium pH and initial concentration of Gd. The optimum extraction time was 90 mins on Gd extraction using resin. The extraction ratio(%) was increased by increasing equilibrium pH from pH 1.0 to 2.0. The experimentally measured amounts of Gd on resins at equilibrium agreed well with those predicted using Freundlich's isotherm.

Experimental Study on a Rotary Magnetic Refrigeration Device (회전식 자기냉동장치에 대한 실험적 연구)

  • Lee Jong Suk;Hong Jeong Ho
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.16 no.12
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    • pp.1101-1106
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    • 2004
  • Magnetic refrigeration is based on the magnetocaloric effect (MCE)-the ability of some materials to heat up when magnetized and cool down when demagnetized. A rotary magnetic refrigeration device using gadolinium (Gd) ribbon and permanent magnets was constructed for experimental study. Gd ribbon attached around a rotating wheel is cyclically magnetized and demagnetized by permanent magnets and exchanges heat with liquid in the surrounding container. Temperature of the liquid in each divided section of the container was measured and the experimental results obtained in this study were discussed.

Anthropogenic Gadolinium (Gd) Inputs into the Ocean: Review and Future Direction (인위적 기원 가돌리늄(gadolinium)의 해양 유입 연구 동향 및 향후 연구 방향)

  • Kim, Intae
    • Ocean and Polar Research
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    • v.43 no.3
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    • pp.165-178
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    • 2021
  • Gadolinium (Gd), one of a rare earth element (REE), has been widely used worldwide since the 1980s, as a resource material for contrast agents injected into examiners of magnetic resonance imaging (MRI) test. The organic complexed form of Gd shows an extremely stable behavior in natural environment (water), so is known that the artificial Gd from medical uses is not removed from the waste water treatment plant (WWTP) and eventually introduced into the ocean through the estuary. Since the 1990s, some previous studies have often been conducted on Gd anomalies in natural water and their effects an artificial origin from land or metropolitan areas, but little research has been potential impacts on the ocean water. In this paper, we review and introduce recent studies related to Gd anomaly in natural water and related marine effects, and also propose the future research directions.

Gadoteridol's Signal Change according to TR, TE Parameters in T1 Image (T1영상에서 TR, TE 매개변수에 따른 Gadoteridol의 신호강도 변화)

  • Jeong, Hyun Keun;Jeong, Hyun Do;Nam, Ki Chang;Kim, Ho Chul
    • Journal of the Institute of Electronics and Information Engineers
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    • v.52 no.9
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    • pp.117-124
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    • 2015
  • In this paper, we introduce how to control TR, TE physical MR parameters for managing $H_1$ spin's SI(Signal Intensity) which is combined with gadolinium following administration MR agent in T1 effect for diagnostic usefulness. we used MRI phantom made with 0.5 mol Gadoteridol. This phantom was scanned by FSE sequence with different TR, TE parameters. In this study, to make T1 effect, TR was 200, 250, 300, 350, 400, 450, 500, 550, 600 msec. In addition to, TE was 6.2, 12.4, 18.6, 21.6 msec. The results were as follows ; Each RSP(Reaction Starting Point) was 100, 50, 40, 30 mmol in TE 6.2, 12.4, 18.6, 21.6 msec being irrelevant to TR. In MPSI(Max Peak Signal Intensity), 4 mmol was showed in TR 200 msec while peak signal was decreased to low concentration mol in TR 250-600 msec. In terms of RA(Reaction Area), the highest SI was TE 6.2 msec in TR 200-600msec. According to the study, we are able to recognize it is possible to control enhance rates by managing TR and TE of MR parameters; moreover, we expect that enhanced T1 image in MR clinical field can be performed in a practical way with this quantitative data.

Comparative Analysis of Quantitative Signal Intensity between 1.0 mol and 0.5 mol MR Contrast Agent (1.0 mol 과 0.5 mol MR조영제의 정량적 신호강도 비교분석)

  • Jeong, Hyun Keun;Jeong, Hyun Do;Nam, Ki Chang;Jang, Geun Yeong;Kim, Ho Chul
    • Journal of the Institute of Electronics and Information Engineers
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    • v.52 no.12
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    • pp.134-141
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    • 2015
  • The purpose on this research is quantitatively comparing and analyzing signal intensity of 1.0mol and 0.5mol contrast agent. For this study, two MR phantoms were produced. One of them is used with 1.0mol Gadobutrol. The other is used with 0.5mol Gadoteridol. These two phantoms respectively have been scanned by SE T1 sequence which is used to get a general contrast-enhanced image in 1.5T MRI and 3D FLASH sequence which is used as enhanced angio MRI. Signal intensity was measured by scanned images as per contrast agent dilution ratio. The results were as follow: RSP(Reaction Starting Point) of the two sequences(2D SE, 3D FLASH) was respectively 6.0%, 60.0% in 0.5mol contrast and 2.0%, 20.0% in 1.0mol contrast, which means in 0.5mol contrast, RSP was formed faster than the one in 1.0mol contrast. MPSI was respectively 1358.8[a.u], 1573[a.u] in 0.5mol contrast and 1374[a.u], 1642.4[a.u] in 1.0mol contrast, which means 0.5mol contrast's MPP (0.4%, 10.0%) was formed faster than 1.0mol contrast's MPP (0.16%, 1.8%). Lastly, RA as per contrast agent dilution ratio was 27.4%, 11.8% wider in 0.5mol contrast(20747.4[a.u], 23204.6[a.u]) than in 1.0mol contrast(12691.9[a.u], 20747.4[a.u]). According to the study, we are able to assure that signal reaction time of 1.0mol contrast is slower than the one of 0.5mol contrast in contrast-enhanced MRI at two different sequences(2D SE, 3D FLASH). Furthermore, owing to the fact that there are not any signal intensity differences between 1.0mol and 0.5mol contrast, it is not true that high concentration gadolinium MR contrast agent does not always mean high signal intensity in MRI.