• The Journal of Internal Korean Medicine
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• v.40 no.5
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• pp.894-900
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• 2019

Objective: The aim of this study was to evaluate the effects of traditional Korean medicine as a treatment for a diabetic patient diagnosed with herniated intervertebral lumbar discs. Methods: We treated the patient with herbal medicines, acupuncture, herbal acupuncture therapy, and physical therapy. We measured the state and progress of this case with the Numerical Rating Scale (NRS) and Oswestry Disability Index (ODI). We also checked serum glucose levels (FBS/PP2hrs) regularly. Results: After treatment, the NRS score was decreased, the ODI score was improved, and the blood glucose level was stabilized. The overall symptoms of the patient showed positive improvement.

• Design & Manufacturing
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• v.13 no.3
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• pp.35-40
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• 2019

As the consumer market in the cosmetic, vehicle manufacturing and aerospace industries grows, the demand for manufacturing industries using on injection mold technology. Also, such manufacturing technology of metal machining is expensive, and the shape is limited. Cosmetic cushion fact products are divided into outer relevant to the exterior of the product and inner containers containing the actual contents. In the case of the inner container, it needs to be combined with the upper and lower cases. As environmental regulations are strengthened internationally, the use of a large number of component parts can result in significant losses in recycling and economics. Therefore, this study aims to perform injection molding analysis through injection molding simulation to develop a cushion fact container that can be recycled through the unification of products and materials using polypropylene to cope with environmental regulations. In the case of injection molding conditions, Injection Time(sec): 4.5, Cooling Time(sec): 13, Resin Temperature($^{\circ}C$): 240, and Pressure(MPa): 30 were determined. The results of injection molding simulation according to the two design methods were compared with the sync mark which shows the problem of filling and injection molding.

• Food Science and Preservation
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• v.6 no.4
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• pp.402-405
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• 1999

Pusan, Kwanagju, Yangjae Floriculture Auction Market to packaging and distribution status of cut flowers in Korean markets from October, 1997 to Feburuary, 1998 this study was surveyed. In case of packaging, the inner packaging materials was used almost used news papers and polyethylene films, the outer box was double wall corrugated paperboard box. Plastic container box was a few. The using shape of box was A-1 type, bending materials was PP film and OPP tape. There was whole sale and retail in all Korean markets in case of distribution. The distribution route was three, the one was farmers through consignments in Seoul to consummers, it was 42% of total distribution volume. The other was auction market in Yangjae, the distribution volume was 18%. The last was distributed in farmers and provincial markets by the dealers, the volume was 40%. All farmers and officers want to applicate the standard regulation of packaging box, but dealers were not.

• Archives of Pharmacal Research
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• v.27 no.1
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• pp.68-76
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• 2004

Mistletoe lectin has been reported to induce apoptosis in different cancer cell lines in vitro and to show antitumor activity against a variety of tumors in animal models. We previously demonstrated the Korean mistletoe lectin (Viscum album var. coloratum, VCA)-induced apoptosis by down-regulation of Bcl-2 and telomerase activity and by up-regulation of Bax through p53- and p21-independent pathway in hepatoma cells. In the present study, we observed the induction of apoptotic cell death through activation of caspase-3 and the inhibition of telomerase activity through transcriptional down-regulation of hTERT in the VCA-treated A253 cells. We also observed the inhibition of telomerase activity and induction of apoptosis resulted from dephosphorylation of Akt in the survival signaling pathways. In addition, combining VCA with the inhibitors of phosphatidylinositol 3-kinase (PI3-kinase) upstream of Akt, wortmannin and LY294002 showed an additive inhibitory effect of telomerase activity. In contrast, the inhibitor of protein phosphatase 2A (PP2A), okadaic acid inhibited VCA-induced dephosphorylation of Akt and inhibition of telomerase activity. Taken together, VCA induces apoptotic cell death through Akt signaling pathway in correlated with the inhibition of telomerase activity and the activation of caspase-3. From these results, together with our previous studies, we suggest that VCA triggers molecular changes that resulting in the inhibition of cell growth and the induction of apoptotic cell death of cancer cells, which suggest that VCA may be useful as chemotherapeutic agent for cancer cells.

• Transactions of Materials Processing
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• v.31 no.6
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• pp.351-364
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• 2022

The yield criterion, or called yield function, plays an important role in the study of plastic working of a sheet because it governs the plastic deformation properties of the sheet during plastic forming process. In this paper, we propose a modified version of previous anisotropic yield function (Trans. Mater. Process., 31(4) 2022, pp. 214-228) based on J2 and J3 stress invariants. The proposed anisotropic yield model has the 6th-order of stress components. The modified version of the anisotropic yield function in this study is as follows. f(J₂⁰,J₃⁰) ≡ (J₂⁰)³ + α(J₃⁰)² + β(J₂⁰)^3/2 × (J₃⁰) = k⁶ The proposed anisotropic yield function well explains the anisotropic plastic behavior of various sheets such as aluminum, high strength steel, magnesium alloy sheets etc. by introducing the parameters α and β, and also exhibits both symmetrical and asymmetrical yield surfaces. The parameters included in the proposed model are determined through an optimization algorithm from uniaxial and biaxial experimental data under proportional loading path. In this study, the validity of the proposed anisotropic yield function was verified by comparing the yield surface shape, normalized uniaxial yield stress value, and Lankford's anisotropic coefficient R-value derived with the experimental results. Application for the proposed anisotropic yield function to AA6016-T4 aluminum and DP980 sheets shows symmetrical yielding behavior and to AZ31B magnesium shows asymmetric yielding behavior, it was shown that the yield locus and yielding behavior of various types of sheet materials can be predicted reasonably by using the proposed anisotropic yield function.

• The korean journal of orthodontics
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• v.49 no.1
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• pp.49-58
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• 2019

Objective: The aim of this retrospective study was to evaluate and compare the changes in the pharyngeal airway (PA), maxillary sinus volume, and skeletal parameters after rapid maxillary expansion (RME) and alternate rapid maxillary expansion and constriction (Alt-RAMEC) followed by facemask (FM) therapy. Methods: The records of 40 patients with skeletal Class III malocclusion due to maxillary retrognathism were collected, and the patients were assigned into two groups. The first group comprised 8 male and 12 female patients (mean age, $10.0{\pm}1.1years$) treated using RME/FM for an average of 10 months. The second group comprised 10 male and 10 female patients (mean age, $9.64{\pm}1.3years$) treated using Alt-RAMEC/FM for an average of 12 months. Cone-beam computed tomography images acquired before (T0) and after treatment (T1) were evaluated. Results: Regarding the skeletal effects, significant differences between the groups were the increase in ANS-HRP (perpendicular distance of ANS to the horizontal reference plane, 0.99 mm, p <0.05) in the Alt-RAMEC/FM group and the decrease in PP-SN (palatal plane to Sella-Nasion plane, $0.93^{\circ}$, p < 0.05) in the RME/FM group. Maxillary sinus volumes increased significantly in both the groups, and the increase was statistically significantly higher in the Alt-RAMEC/FM group. Although no significant intergroup differences were observed in PA volumes, both lower ($1,011.19mm^3$) and total ($1,601.21mm^3$), PA volume increased significantly in the Alt-RAMEC/FM group. Conclusions: The different expansion devices and protocols used with FM therapy do not seem to affect the forward movement of the maxilla and PA volumes. In contrast, the increase in maxillary sinus volume was greater in the Alt-RAMEC/FM protocol.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2019.04a
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• pp.94-94
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• 2019

In this study, we elucidated the anti-inflammatory mechanisms of leaves extracts from Rodgersia podophylla (RPL) in RAW264.7 cells. RP-L significantly inhibited the production of the proinflammatory mediators such as NO, iNOS, IL-$1{\beta}$ and IL-6 in LPS-stimulated RAW264.7 cells. RPL increased HO-1 expression in RAW264.7 cells, and the inhibition of HO-1 by ZnPP reduced the inhibitory effect of RPL against LPS-induced NO production in RAW264.7 cells. Inhibition of p38, ROS and $GSK3{\beta}$ attenuated RPL-mediated HO-1 expression. Inhibition of ROS inhibited p38 phosphorylation and $GSK3{\beta}$ expression induced by RPL. In addition, inhibition of $GSK3{\beta}$ blocked RPL-mediated p38 phosphorylation. RPL induced nuclear accumulation of Nrf2, and Inhibition of p38, ROS and $GSK3{\beta}$ abolished RPL-mediated nuclear accumulation of Nrf2. Furthermore, RPL blocked LPS-induced degradation of $I{\kappa}B-{\alpha}$ and nuclear accumulation of p65. RP-L also attenuated LPS-induced phosphorylation of ERK1/2 and p38. Our results suggest that RPL exerts potential antiinflammatory activity by activating ROS/$GSK3{\beta}$/p38/Nrf2/HO-1 signaling and inhibiting NF-${\kappa}B$ and MAPK signaling in RAW264.7 cells. These findings suggest that RPL may have great potential for the development of anti-inflammatory drug.

• Journal of Broadcast Engineering
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• v.23 no.6
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• pp.824-835
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• 2018

In this study, the impact on the number of cable TV subscribers as well as the profit of cable TV has been examined, and the impact on enlarging the digital broadcast viewing rights of cable TV subscribers and viewers' welfare has also been examined. We investigated the trends in the number of analog and 8VSB subscribers and revenue of cable TV operators by region and analyzed based on changes in the number of channels provided by each operator. The results show that analog subscribers and digital subscribers are delaying their departure through 8VSB conversion, and VOD subscription fees and home shopping transmission fees have a significant impact on operating profit. Subscribers, as they switched over to 8VSB, have become able to view channels of various genres with clear picture quality for a same subscription fee, and the program providers could offer programs to more customers. The government's deregulation policy due to the changes in broadcasting environment led to the facilitation of digital conversion of Pay-TV and improvement of viewers' welfare.

• Journal of the Korean Institute of Gas
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• v.23 no.1
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• pp.47-53
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• 2019

A variety of general purpose polymer products such as polyethylene (PE), polypropylene (PVC), polyvinyl chloride (PVC), polystyrene (PS) and polyurethane (PU) are widely produced and used in the industrial field. Many industrial accidents have occurred due to fire and explosion at the manufacturing site. In order to prevent such accidents, it is important to collect and analyze accident cases that occurred in the past to identify the characteristics of accidents and to use them to prevent the same kind of accidents or similar accidents. In this study, the accident distribution characteristics of general polymer manufacturing process were examined by using SPSS based on the database of the industrial accident statistics system operated by the Korea Occupational Safety and Health Agency. These results can be used to prevent accidents in the general-purpose polymer product process and ensure the safety of the process.

• Earthquakes and Structures
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• v.16 no.4
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• pp.469-485
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• 2019

A numerical investigation regarding local (${\mu}_L$) and story (${\mu}_S$) ductility demand evaluation of steel buildings with perimeter moment resisting frames (PMRF) and interior gravity frames (IGF), is conducted in this study. The interior connections are modeled, firstly as perfectly pinned (PP), and then as semi-rigid (SR). Three models used in the SAC steel project, representing steel buildings of low-, mid-, and high-rise, are considered. The story ductility reduction factor ($R_{{\mu}S}$) as well as the ratio ($Q_{GL}$) of $R_{{\mu}S}$ to ${\mu}_L$ are calculated. ${\mu}_L$ and ${\mu}_S$, and consequently structural damage, at the PMRF are significant reduced when the usually neglected effect of SR connections is considered; average reductions larger than 40% are observed implying that the behavior of the models with SR connections is superior and that the ductility detailing of the PMRF doesn't need to be so stringent when SR connections are considered. $R_{{\mu}S}$ is approximately constant through height for low-rise buildings, but for the others it tends to increase with the story number contradicting the same proportion reduction assumed in the Equivalent Static Lateral Method (ESLM). It is implicitly assumed in IBC Code that the overall ductility reduction factor for ductile moment resisting frames is about 4; the results of this study show that this value is non-conservative for low-rise buildings but conservative for mid- and high-rise buildings implying that the ESLM fails evaluating the inelastic interstory demands. If local ductility capacity is stated as the basis for design, a value of 0.4 for $Q_{GL}$ seems to be reasonable for low- and medium-rise buildings.