• The Transactions of the Korean Institute of Power Electronics
• /
• v.4 no.3
• /
• pp.304-309
• /
• 1999

In this paper, a new 24longleftarrowpulse diode rectifier system based upon the conventional series-connected 12-pulse rectifier is p proposed with the least number of switching devices and low VA rating of the additional passive components. The p proposed approach does not employ any active switching devices. Therefore, the system is rugged and simple to i implement. Detailed analysis with VA rating calculation of the components is presented and experimental results from a a 220V, 3kV A rectifier system verify the proposed concept.

• Journal of the Korea Institute of Building Construction
• /
• v.18 no.2
• /
• pp.99-107
• /
• 2018

The objective of the present study is to propose a reliable shape of supplementary V-ties in the section jacketing approach for seismic strengthening of reinforced concrete columns. A total of 24 pull-out specimens were prepared. The test parameters selected with regard to bond strength of V-ties were the shape of V-ties, embedment length of V-tie legs, and compressive strength of concrete. The measured bond strength of V-ties with different shapes were compared with that of the conventional V-ties and predictions using CEB-FIP equation. Ultimately, V-ties with pressed end-details at their legs could be recommended for the supplementary lateral reinforcement of strengthening columns with jacketing thickness less than the embedment length [= max (75mm, $6d_b$)] of conventional V-ties, where $d_b$ is the diameter of the reinforcing bar used for V-ties.

• Geophysics and Geophysical Exploration
• /
• v.17 no.2
• /
• pp.66-73
• /
• 2014

To estimate the shear-velocity ($v_s$) structure beneath the WIZ station on White Island in New Zealand, we applied receiver function (RF) inversion and H-${\kappa}$ stacking methods to 362 teleseismic events (Mw > 5.5) recorded during April 20, 2007 to September 6, 2013. Using 71 RFs with errors less than 20% after 200 iterative computations, we determined that the depth to Moho of $v_s$ = 4.35 km/s is $24{\pm}1km$ within a 15 km radius of the station. In an 1-d $v_s$ model derived by RF inversions, a 4-km thick low-velocity layer (LVL) at depths of 18 ~ 22 km was identified in the lower crust. This LVL, which is 0.15 km/s slower than the rocks above and below it, may indicate the presence of a deep magma reservoir. The H-${\kappa}$ stacking method yielded an estimate of the depth to the Moho of 24.5 km, which agrees well with the depth determined by RF inversions. The low $v_p/v_s$ ratio of 1.64 may be due to the presence of gas-filled rock or hot crystallizing magma.

• Journal of IKEEE
• /
• v.24 no.4
• /
• pp.1172-1175
• /
• 2020

Automotive ECU integrates CPU core, IVN controller, memory interface, sensor interface, I/O interface, and so on. Current automotive ECUs are often developed with proprietary processor architectures. However, demends for standard processors such as ARM and RISC-V increase rapidly for saftware compatibility in autonomous vehicles and connected cars. In this paper, an automotive ECU is designed for parking assist system based on RISC-V with open instruction set architecture. It includes 32b RISC-V CPU core, IVN controllers such as CAN and LIN, memory interfaces such as ROM and SRAM, and I/O interfaces such as SPI, UART, and I2C. Fabricated in 65nm CMOS technology, its operating frequency, area, and gate count are 50MHz, 0.37㎟, and 55,310 gates, respectively.

• Biomolecules & Therapeutics
• /
• v.29 no.3
• /
• pp.282-289
• /
• 2021

A novel coronavirus, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), caused a worldwide pandemic. Our aim in this study is to produce new fusion inhibitors against SARS-CoV-2, which can be the basis for developing new antiviral drugs. The fusion core comprising the heptad repeat domains (HR1 and HR2) of SARS-CoV-2 spike (S) were used to design the peptides. A total of twelve peptides were generated, comprising a short or truncated 24-mer (peptide #1), a long 36-mer peptide (peptide #2), and ten peptide #2 analogs. In contrast to SARS-CoV, SARS-CoV-2 S-mediated cell-cell fusion cannot be inhibited with a minimal length, 24-mer peptide. Peptide #2 demonstrated potent inhibition of SARS-CoV-2 S-mediated cell-cell fusion at 1 µM concentration. Three peptide #2 analogs showed IC50 values in the low micromolar range (4.7-9.8 µM). Peptide #2 inhibited the SARS-CoV-2 pseudovirus assay at IC50=1.49 µM. Given their potent inhibition of viral activity and safety and lack of cytotoxicity, these peptides provide an attractive avenue for the development of new prophylactic and therapeutic agents against SARS-CoV-2.

• Journal of Radiation Protection and Research
• /
• v.35 no.2
• /
• pp.85-90
• /
• 2010

In the present work, peak relative efficiency for the energy was obtained and response function was worked out. This study was carried out using the high resolution high efficiency HPGe detector(diameter 78.7 mm, length 86.5 mm) and NaI(Tl) detector for anti-compton. The anti-coincidence of the signals from the two detectors could be used to lessen the Compton effect signal; thus, the $\gamma$-ray energy resolution could be improved. The $\gamma$-ray spectrum was measured at $55^{\circ}$ to the direction of the incident proton beam. Reaction spectrum was obtained from the $^{23}Na$(p, $\gamma$)$^{24}Mg$ reaction at $E_p$ = 1424 keV and $^{27}Al$(p, $\gamma$)$^{28}Si$ reaction at $E_p$ = 992 keV. To accelerate the incident proton which creates the (p, $\gamma$) capture reaction, the 3 MeV Pelletron accelerator at the Tokyo Institute of Technology was used. Response function was worked out by a noble technique. We worked out a response function from 1.2 to 9.4 MeV at intervals of 0.75 MeV.

• Biomedical Science Letters
• /
• v.24 no.4
• /
• pp.390-397
• /
• 2018

For the specific detection of human Parvovirus B19 (HuPaV-B19), we designed ten specific PCR primers from 3,800~4,500 nucleotides of HuPaV-B19 complete genome (NC_000883.2). Seventeen candidate PCR primer sets for specific detecting HuPaV-B19 were constructed. In specific reaction of HuPaV-B19, seventeen PCR primer sets showed specific band, however five PCR primer sets were selected basis of band intensity, amplicon size and location. In non-specific reaction with seven reference viruses, four PCR primer sets showed non-specific band, however one PCR primer set is not. Detection sensitivity of final selective PCR primer set was $100fg/{\mu}L$ for 112 minute, and PCR amplicon is 539 base pairs (bp). In addition, nested PCR primer set was developed, for detection HuPaV-B19 from a low concentration of contaminated samples. Selection of nested PCR primer set was basis of sensitivity and groundwater sample tests. Detection sensitivity of final selective PCR and nested PCR primer sets for the detection of HuPaV-B19 were $100fg/{\mu}L$ and $100ag/{\mu}L$ basis of HuPaV-B19 plasmid, it was able to rapid and highly sensitive detection of HuPaV-B19 than previous reports. We expect developed PCR primer set in this study will used for detection of HuPaV-B19 in various samples.

• Journal of Sensor Science and Technology
• /
• v.5 no.2
• /
• pp.1-8
• /
• 1996

In this paper, We have designed silicon pressure sensor with center-bossed diaphragm which improving sensitivity and linearity by reducing diaphragm deflection. Designed center-bossed pressure sensor showed maximum deflection of $0.125{\mu}m$, maximum stress of $2.24{\times}10^7 Pa$ and sensitivity of 27.67 mV/V.psii. As a result, diaphragm deflection was reduced to 1/160 that of diaphragm thickness and 1/35 that of square diaphragm. Also, sensitivity was increased 19 times compared to square diaphragm.

• Journal of IKEEE
• /
• v.24 no.3
• /
• pp.853-858
• /
• 2020

This paper proposes a 2-ch DC-DC converter for OLED display with immunity against RF noise inserted from communication device. For RF signal immunity, an input voltage variation reduction circuit that attenuates as much as the input voltage variation is embedded. The boost converter for positive voltage V_POS operates in SPWM-PWM dual mode and has a dead time controller to increase power efficiency. The inverting charge pump for negative voltage V_NEG is a 2-phase scheme and operates in PFM using VCO to reduce output ripple voltage. Simulation results using 0.18 ㎛ BCDMOS process show that the overshoot and undershoot of the output voltage decrease from 10 mV to 2 mV and 5 mV, respectively. The 2-ch DC-DC converter has power efficiency of 39%~93%, and the power efficiency of the boost converter is up to 3% higher than the conventional method without dead time controller.

• Journal of Veterinary Science
• /
• v.23 no.2
• /
• pp.27.1-27.16
• /
• 2022

Background: The role of Toll-like receptors (TLRs) in a feline infectious peritonitis virus (FIPV) infection is not completely understood. Objectives: This study examined the expression of TLR3, TLR7, TLR9, tumor necrosis factor-alpha (TNF-α), interferon (IFN)-β, and interleukin (IL)-10 upon an FIPV infection in Crandell-Reese feline kidney (CRFK) cells and feline monocytes. Methods: CRFK cells and monocytes from feline coronavirus (FCoV)-seronegative cats and FCoV-seropositive cats were infected with type II FIPV-79-1146. At four, 12, and 24 hours post-infection (hpi), the expression of TLR3, TLR7, TLR9, TNF-α, IFN-β, and IL-10, and the viral load were measured using reverse transcription quantitative polymerase chain reaction. Viral protein production was confirmed using immunofluorescence. Results: FIPV-infected CRFK showed the upregulation of TLR9, TNF-α, and IFN-β expression between 4 and 24 hpi. Uninfected monocytes from FCoV-seropositive cats showed lower TLR3 and TLR9 expression but higher TLR7 expression compared to uninfected monocytes from FCoV-seronegative cats. FIPV-infected monocytes from FCoV-seropositive cats downregulated TLR7 and TNF-α expression between 4 and 24 hpi, and 4 and 12 hpi, respectively. IFN-β was upregulated early in FIPV-infected monocytes from FCoV-seropositive cats, with a significant difference observed at 12 hpi compared to FCoV-seronegative cats. The viral load in the CRFK and FIPV-infected monocytes in both cohorts of cats was similar over time.ConclusionTLR7 may be the key TLR involved in evading the innate response against inhibiting TNF-α production. Distinct TLR expression profiles between FCoV-seronegative and FCoV-seropositive cats were observed. The associated TLR that plays a role in the induction of IFN-β needs to be explored further.