• Title/Summary/Keyword: $R_s$

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INJECTIVE PROPERTY OF LAURENT POWER SERIES MODULE

  • Park, Sang-Won
    • East Asian mathematical journal
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    • v.17 no.2
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    • pp.367-374
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    • 2001
  • Northcott and McKerrow proved that if R is a left noetherian ring and E is an injective left R-module, then $E[x^{-1}]$ is an injective left R[x]-module. Park generalized Northcott and McKerrow's result so that if R is a left noetherian ring and E is an injective left R-module, then $E[x^{-S}]$ is an injective left $R[x^S]$-module, where S is a submonoid of $\mathbb{N}$($\mathbb{N}$ is the set of all natural numbers). In this paper we extend the injective property to the Laurent power series module so that if R is a ring and E is an injective left R-module, then $E[[x^{-1},x]]$ is an injective left $R[x^S]$-module.

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Circulating Levels of Interleukin-6 and Soluble Interleukin-6 Receptor in Acute Asthma (급성 천식환자에서 혈중 Interleukin-6 및 Soluble Interleukin-6 수용체의 변화)

  • Lee, Kyoung-Hoon;Lee, Yong-Chul;Cheon, Ki-Tae;Lee, Heung-Bum;Rhee, Yang-Keun
    • Tuberculosis and Respiratory Diseases
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    • v.48 no.4
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    • pp.464-470
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    • 2000
  • Background : The recognition of bronchial asthma as an inflammatory disease led to the search for soluble markers that would be useful in assessing airway inflammation. Interleukin-6 (IL-6) is a representative proinflammatory cytokine that has been shown to be connected with various inflammatory diseases. IL-6 acts via specific receptors that consist of the IL-6 binding glycoprotein gp80 and the signal transducer gp130. In the search for markers of airway inflammation, delete the role of soluble interleukin-6 receptor (sIL-6R) and IL-6 in acute asthma were investigated. Methods : Serum levels of sIL-6R and IL-6 were measured in 78 acute asthmatics, in 15 patients with asymptomatic asthma and in 10 healthy control subjects by a specific ELISA using a murine antihuman IL-6R, IL-6 mAb ($Quantikine^{(R)}sIL$-6R, IL-6). Results : Serum levels of IL-6 in acute asthmatics significantly exceeded those of control subjects. The levels of sIL-6R in acute asthmatics were also significantly increased compared to those of control subjects. The serum concentrations of IL-6 obtained in acute asthmatics were elevated compared with those in asymptomatic asthmatics. However, association between eosinophilic count/IgE and IL-6/sIL-6R in acute asthma could not be found. Conclusion : Our results suggest that IL-6 may be involved in the pathogenesis of acute asthma, and serum levels of IL-6 and sIL-6R may reflect the severity of airway inflammation.

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Comparison of shaping ability between various hybrid instrumentation methods with ProTaper (ProTaper를 사용한 다양한 hybrid instrumentation methods의 근관성형 효율 비교)

  • Hong, Eun-Sook;Park, Jeong-Kil;Hur, Bock;Kim, Hyeon-Cheol
    • Restorative Dentistry and Endodontics
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    • v.31 no.1
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    • pp.11-19
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    • 2006
  • The purpose of this study was to compare and evaluate the shaping abilities of various hybrid instrumentation method using constant tapered file systems with $ProTaper\^{(R)}$ S1 and the difference between experts and inexperienced clinicians in use of NiTi file. Three hybrid methods used in this study were composed of $ProTaper\^{(R)}\;S1\;and\;K-Flexofile\^{(R)}\;(group S),\;ProTaper\^{(R)}\;S1\;and\;HeroShaper\^{(R)}\;(group\;H),\;and\;ProTaper\^{(R)}\;S1\;and\;ProFile\^{(R)}\;(group\;P)$respectively. The $ProTaper\^{(R)}$-alone method (group C) was introduced as a control group. After canal preparation, the lapse of time was recorded. The images of pre- and post-operative canal were scanned and superimposed. Amounts of instrumented canal widths and centering ratio were measured at apical 1, 2 and 3 mm levels and statistical analysis was performed In this study. both of the group C and S took more time to prepare canals than other groups, Inexperienced operators required more time for the entire preparation with the groups C and H than the experienced (p<0.05). And the centering ratio of group P were preferable to $ProTaper\^{(R)}$-alone method or the hybrid technique using stainless steel files. As such, within experienced operators, group H also showed better results in addition to the group P. Under these condition, the hybrid methods of each the $ProFile^{(R)}$ system and $HeroShaper^{(R)}$ with ProTaper are recommendable comparative to $ProTaper\^{(R)}$-alone method. According to the results, the hybrid instrumentation method is a more appropriate method of canal preparation than single file system for narrow or curved canals.

Comparison of the safety and immunogenicity of commercial S. gallinarum 9R vaccine (국내 시판 Salmonella gallinarum 9R vaccine의 안전성 및 면역원성 비교)

  • Hwang, Jei Kiun;Lee, Young Ju
    • Korean Journal of Veterinary Research
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    • v.49 no.2
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    • pp.127-133
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    • 2009
  • Salmonella enterica subsp. enterica serovar gallinarum (S. gallinarum) is the agent of fowl typhoid, and the 9R vaccine is a commercial live vaccine for the prevention of fowl typhoid. The aim of this study was to assess the safety and immunogenicity of different brands of S. gallinarum 9R vaccine used in commercial laying chickens in Korea. All 9R strains originated from three different brands showed the same pattern in the biochemical and serological properties, and pulsed field gel electrophoresis (PFGE) profile. But, there was a difference in rhamnose fermentaion, agglutination with Salmonella group $D_1$ antiserum and PFGE pattern between 9R vaccine strain and field S. gallinarum isolates. In laboratory and field trials for assesment of safety and immunogenicity of 9R vaccine, all of the three 9R vaccines showed the same safety in commercial laying chickens. In addition, there was a significant difference between the vaccinated and unvaccinated control groups in mortality and the re-isolation rate of the challenge strain from the tissues (p < 0.05), and no difference by the brands of 9R vaccine. The results from this study indicated that all three different brands of S. gallinarum 9R vaccine showed highly protection against mortality and organ invasion in commercial laying chickens exposed to virulent strains of S. gallinarum.

Effects of $(1R,9S)-{\beta}-Hydrastine$ hydrochloride on L-DOPA-Induced Cytotoxicity in PC12 cells

  • Yin, Shou-Yu;Lee, Jae-Joon;Kim, Yu-Mi;Jin, Chun-Mei;Yang, Yoo-Jung;Lee, Myung-Koo
    • Natural Product Sciences
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    • v.10 no.3
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    • pp.124-128
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    • 2004
  • Previously, $(1R,9S)-{\beta}-Hydrastine$ hydrochloride has been found to lower dopamine content in PC12 cells (Kim et al., 20001). In this study, the effects of $(1R,9S)-{\beta}-Hydrastine$ hydrochloride on L-DOPA-induced cytotoxicity in PC12 cells were investigated. Treatment with $(1R,9S)-{\beta}-Hydrastine$ hydrochloride at concentrations higher than $500\;{\mu}M$ caused cytotoxicity in PC12 cells. In addition, $(1R,9S)-{\beta}-Hydrastine$ hydrochloride at non-cytotoxic or cytotoxic concentrations significantly enhanced L-DOPA-induced cytotoxicity (L-DOPA concentration, $50\;{\mu}M$). Treatment of PC12 cells with $750\;{\mu}M$ $-1R,9S)-{\beta}-Hydrastine$ hydrochloride and $50\;{\mu}M$ L-DOPA, alone or in combination, also induced cell death via a mechanism which exhibited morphological and biochemical characteristics of apoptosis, including chromatin condensation and membrane blebbing. Exposure of PC12 cells to $(1R,9S)-{\beta}-Hydrastine$ hydrochloride, L-DOPA and $(1R,9S)-{\beta}-Hydrastine$ hydrochloride plus L-DOPA for 48 h resulted in a marked increase in the cell loss and percentage of apoptotic cells compared with exposure for 24 h. These data indicate that $(1R,9S)-{\beta}-Hydrastine$hydrochloride at higher concentration ranges aggravates L-DOPA-induced neurotoxicity cytotoxicity in PC12 cells. Therefore, it is proposed that the long-term L-DOPA therapeutic patients with $(1R,9S)-{\beta}-Hydrastine$ hydrochloride could be checked for the adverse symptoms.

Determination of the Structure of 5S rRNA from Xanthomonas citri (Xanthomonas citri의 5S rRNA 의 구조 결정)

  • Bongrae Cho;Myung-Un Choi;Se Won Seh;ahei Ihm;Moonjoo Koh;Inwon Park
    • Journal of the Korean Chemical Society
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    • v.36 no.3
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    • pp.460-465
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    • 1992
  • The structure of th 5S rRNA isolated from Xanthomonas citri was determined by enzymatic and chemical degradation methods. It consists of 119 nucleotides and contains no modified nucleosides. As does the 5S rRNA of X. maltophilia, it contains an additional uridine residue on the 5'-terminus. The secondary structure of the 5S rRNA from X. citri was almost identical to the generalized models proposed by many other workers [De Wachter et al., Biochimie, 64, 311 (1982); Specht et al., Nucleic Acids Res., 18, 2215 (1990); Cho et al., Proceedings of the First Symposium on Biomolecules, p. 9 (1991)]. The secondary structure of 5S rRNA from X. citri consists of five helices, five loops and two bulges. This 5S rRNA has a uridine residue at position 66 as a bulge.

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An (r,s)-derived sets and double fuzzy closure operators

  • Zahran, Ahmed M.;Abd-Allah, M. Azab;EI-Saady, Kamal;EI-Rahman, Abd EI-Nasser G. Abd
    • International Journal of Fuzzy Logic and Intelligent Systems
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    • v.8 no.1
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    • pp.6-10
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    • 2008
  • In this paper, we introduce the concept of fuzzy (r, s)-adherence points, fuzzy (r, s)-accumulation points and fuzzy (r, s)-derived sets in double fuzzy topology. We investigate some of their properties. The relationship with double fuzzy closure operator was studied.