• Archives of Pharmacal Research
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• v.27 no.1
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• pp.111-117
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• 2004

Hepatic microcirculatory failure is a major component of reperfusion injury in the liver. Recent data provided some evidence that endothelium-derived vasoconstrictors and vasodilators may be functionally important to the control of the total hepatic blood flow under these conditions of circulatory failure. Since Kupffer cells provide signals that regulate the hepatic response in ischemia/reperfusion (I/R), the aim of this study was to investigate the role of Kupffer cells in the I/R-induced imbalance of vasoregulatory gene expression. Rats were subjected to 60 min hepatic ischemia, followed by 5 h of reperfusion. The Kupffer cells were inactivated by gadolinium chloride ($GdCl_3$, 7.5 mg/kg body weight, intravenously) 1 day prior to ischemia. Liver samples were obtained 5 hrs after reperfusion for RT-PCR analysis of the mRNA for genes of interest: endothelin-1 (ET-1), its receptors $ET_A and ET_B$, endothelial nitric oxide synthase (eNOS), inducible nitric oxide synthase (iNOS) and heme oxygenase-1 (HO-1). ET-1 mRNA expression was increased by I/R. mRNA levels for $ET_A$ receptors showed no change, whereas $ET_B$ receptor transcripts increased in the I/R group. The increases in ET-1 and $ET_B$ mRNA were not prevented by the $GdCI_3$ pretreatment. The mRNA levels for iNOS and eNOS significantly increased within the I/R group with no significant difference between the I/R group and the $GdCl_3$-treated I/R group. HO-1 mRNA expression significantly increased in the I/R group and this increase was attenuated by $GdCI_3$. In conclusion, we have demonstrated that an imbalance in hepatic vasoregulatory gene expression occurs during I/R. Our findings suggest that the activation of Kupffer cells is not required for I/R-induced hepatic microvascular dysfunction.

• Journal of Korean Institute of Industrial Engineers
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• v.30 no.3
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• pp.250-260
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• 2004

This study considers a linear connected-(r,s)-out-of-(m,n):F lattice system whose components are ordered like the elements of a linear (m,n )-matrix. We assume that all components are in the state 1 (operating) or 0 (failed) and identical and s-independent. The system fails whenever at least one connected (r,s)-submatrix of failed components occurs. The purpose of this paper is to present an optimization scheme that aims at minimizing the expected cost per unit time. To find the optimal threshold of maintenance intervention, we use a genetic algorithm for the cost optimization procedure. The expected cost per unit time is obtained by Monte Carlo simulation. The sensitivity analysis to the different cost parameters has also been made.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2019.05a
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• pp.250-251
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• 2019

Lots of infrastructures have been newly constructed through the rapid economic growth of 1970's. Since the infrastructures has mostly deteriorated and this circumstance makes the need for maintenance and rehabilitation(M&R) of infrastructures to obtain the convenience and safety of users even more essential. Although markets for M&R project become larger, the construction standards for cost estimation of M&R work are insufficient. Thus, the purpose of this study is to examine the present state of standards for cost estimation of M&R works using case studies. Finally, this work could be utilized as the basis for the development of national standard for estimation of M&R work.

• Bulletin of the Korean Mathematical Society
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• v.57 no.6
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• pp.1567-1579
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• 2020

Let R ⊂ S be a Frobenius extension of rings and M a left S-module and let 𝓧 be a class of left R-modules and 𝒚 a class of left S-modules. Under some conditions it is proven that M is a 𝒚-Gorenstein left S-module if and only if M is an 𝓧-Gorenstein left R-module if and only if S ⊗_R M and Hom_R(S, M) are 𝒚-Gorenstein left S-modules. This statement extends a known corresponding result. In addition, the situations of Ding modules, Gorenstein AC modules and projectively coresolved Gorenstein flat modules are considered under Frobenius extensions.

• Bulletin of the Korean Chemical Society
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• v.20 no.1
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• pp.65-68
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• 1999

Novel mononuclear group 13 metal complexes with the formula (R2M){NC5H4C(CH3)NNC(S)NH(C6H5)} (M=Al, R=iC4H9 (1); M=Ga, R=iC4H9 (2); M=Al, R=CH2SiMe3 (3); M=Ga, R=CH2SiMe3 (4)) result when 2-acetyl pyridine 4-phenyl-thiosemicarbazone ligand is mixed with trialkyl aluminum or trialkylgallium. These compounds 1-4 are characterized by microanalysis, NMR (1H, 13C) spectroscopy, mass spectra, and singlecrystal X-ray diffraction. X-ray single-crystal diffraction analysis reveals that 1 is mononuclear metal compound with coordination number of 5 and N, N, S-coordination mode.

• Journal of the Korea Organic Resources Recycling Association
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• v.9 no.4
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• pp.55-60
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• 2001

This study was performed to investigate production characterisitic of methane gas in anaerobic digestion reactor according to input type of food waste. In the production rates of $CH_4$ gas per g $VS_{added}$, reactor R2, R3, R4, R5, and R6 in which sewage sludge and food waste were combined with mixing ratio of 1:0.1, 1:0.3, 1:0.5, 1:1, and 1:2 showed 85mL, 62mL, 67mL, 72mL, and 73mL $CH_4/g$ $VS_{added}$ which were much more than sewage sludge digestion alone. Methane content according to crushing size of food waste respectively showed 51.1%(raw food), 53.1%(2~4mm), and 50.6%(<2mm), In case of methane production according to washing of food waste, R12(7~8 times washing) showed the highest methane production.

• Korean Journal of Optics and Photonics
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• v.18 no.5
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• pp.333-336
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• 2007

A Strained Layer Multiquantum-Well (SL-MQW) distributed feedback laser at a wavelength of 1.31 um operating from $-40^{\circ}C$ to $85^{\circ}C$ without any cooling is grown by metal-organic chemical vapor deposition (MOCVD). Lasers with high slope efficiency are achieved through careful optimization of a SL-MQW active layer, especiallyoptimizing the amount of strain, the well thickness, the barrier thickness, the number of wells, and the active layer width. In this paper, we obtain the slope efficiencies of 0.38[mW/mA] and 0.26 [mW/mA] at $25^{\circ}C$ and $85^{\circ}C$, respectively. Threshold currents are 7.1[mA] and 19.8[mA] at $25^{\circ}C$ and $85^{\circ}C$, respectively.

• Journal of Applied Biological Chemistry
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• v.63 no.2
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• pp.125-129
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• 2020

Environmental pollution caused by various heavy metals is a serious global problem. To solve this problem, microbial bioremediation of contaminated metals has developed rapidly as an effective strategy when physical and chemical techniques are not suitable. In this study, cadmium (Cd)-tolerant soil bacteria were isolated via artificial induction in laboratory conditions instead of screening bacteria naturally adapted to metal-contaminated soils. Wild-type (WT) bacteria grown in uncontaminated soils were artificially and sequentially adapted to gradually increasing Cd concentrations of up to 15 mM. The resultant cells, named Soil-CdR15, survived at a Cd concentration of 10 mM, whereas WT cells failed to survive with 4 mM Cd on solid media for 2 d. In liquid media containing Cd, the SoilCdR15 cells grew with 15 mM Cd for 7 d, whereas the WT cells could not grow with 5 mM Cd. Both Soil-CdR15 and WT cells removed approximately 35% of Cd at the same capacity from liquid media containing either 0.5 or 1.0 mM Cd over 2 d. In addition to Cd, the Soil-CdR15 cells showed increased resistance to nickel, zinc, and arsenic compared to WT cells. The Soil-CdR cells were identified as Burkholderia sp. by partial sequencing of 16S rRNA. The data presented in this study demonstrate that isolation of heavy metal-tolerant microorganisms via artificial induction in laboratory conditions is possible and may be useful for the application of the microorganisms for the bioremediation of heavy metals.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.37 no.12
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• pp.1-9
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• 2000

A new method, the external resistance method (ERM method), is proposed for accurate extraction of the gate bias-dependent effective channel carrier mobility (${\mu}_{eff}$) and separated parasitic source/drain resistances ($R_S$ and $R_D$) of n-channel MOSFET's. The proposed ERM method is applied to n-channel LDD MOSFETs with two different gate lengths ($W_m/L_m=30{\mu}m/0.6{\mu}m,\;30{\mu}m/1{\mu}m$) in the linear mode of current-voltage characteristics ($I_D-V_{GS},\;V_{DS}$). We also considered gate voltage dependence of separated $R_2$ and $R_D$ in the accurate modeling and extraction of effective channel carrier mobility. Good agreement of experimental data is observed in submicron n-channel LDD MOSFETs. Combining with capacitance-voltage characteristics, the ERM method is expected to be very useful for accurate and efficient extraction of ${\mu}_{eff},\;R_D,\;R_S$, and other characteristic parameters in both symmetric and asymmetric structure MOSFET's in which parasitic resistances are critical to the improvement of high speed performance and reliability.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.17 no.12
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• pp.2875-2882
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• 2013

The design of PN(Pseudo Noise) sequences with good cross-correlation properties is important for many research areas in communication systems. Also analyses of cross-correlation frequency between designed sequences have been researched. In this paper we analyze of cross-correlation distribution and properties of non-linear binary sequences family $S^r=\{Tr^m_1\{[Tr^n_m(a{\alpha}^t+{\alpha}^{dt}]^r\}{\mid}a{\in}GF(2^m),0{\leq}t &lt; 2^n-1\}$, where $gcd(r,2^m-1)=1$ with 5-valued cross-correlation.