• Title/Summary/Keyword: $N_2$N

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Embedding Algorithm of 2$^{2n-k}$$\times$2$^{k}$ Torus on HCN(n,n) (2$^{2n-k}$$\times$2$^{k}$ 토러스의 HCN(n,n)에 대한 임베딩 알고리즘)

  • 강민식;김종석;이형옥;허영남
    • Proceedings of the Korean Information Science Society Conference
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    • 2002.04a
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    • pp.697-699
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    • 2002
  • 임베딩은 어떤 연결망이 다른 연결망 구조에 포함 흑은 어떻게 연관되어 있는지를 알아보기 위해 어떤 특정한 연결망을 다른 연결망에 사상하는 것으로, 특정한 연결망에서 사용하던 여러 가지 알고리즘을 다른 연결망에서 효율적으로 이용할 수 있도록 한다. 본 논문에서는 2$^{2n-k}$ $\times$2$^{k}$ 토러스를 HCN(n,n)에 연장율 3에 임베딩 가능함을 보인다.

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A 2kβ Algorithm for Euler function 𝜙(n) Decryption of RSA (RSA의 오일러 함수 𝜙(n) 해독 2kβ 알고리즘)

  • Lee, Sang-Un
    • Journal of the Korea Society of Computer and Information
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    • v.19 no.7
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    • pp.71-76
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    • 2014
  • There is to be virtually impossible to solve the very large digits of prime number p and q from composite number n=pq using integer factorization in typical public-key cryptosystems, RSA. When the public key e and the composite number n are known but the private key d remains unknown in an asymmetric-key RSA, message decryption is carried out by first obtaining ${\phi}(n)=(p-1)(q-1)=n+1-(p+q)$ and then using a reverse function of $d=e^{-1}(mod{\phi}(n))$. Integer factorization from n to p,q is most widely used to produce ${\phi}(n)$, which has been regarded as mathematically hard. Among various integer factorization methods, the most popularly used is the congruence of squares of $a^2{\equiv}b^2(mod\;n)$, a=(p+q)/2,b=(q-p)/2 which is more commonly used then n/p=q trial division. Despite the availability of a number of congruence of scares methods, however, many of the RSA numbers remain unfactorable. This paper thus proposes an algorithm that directly and immediately obtains ${\phi}(n)$. The proposed algorithm computes $2^k{\beta}_j{\equiv}2^i(mod\;n)$, $0{\leq}i{\leq}{\gamma}-1$, $k=1,2,{\ldots}$ or $2^k{\beta}_j=2{\beta}_j$ for $2^j{\equiv}{\beta}_j(mod\;n)$, $2^{{\gamma}-1}$ < n < $2^{\gamma}$, $j={\gamma}-1,{\gamma},{\gamma}+1$ to obtain the solution. It has been found to be capable of finding an arbitrarily located ${\phi}(n)$ in a range of $n-10{\lfloor}{\sqrt{n}}{\rfloor}$ < ${\phi}(n){\leq}n-2{\lfloor}{\sqrt{n}}{\rfloor}$ much more efficiently than conventional algorithms.

The Study of Cyclophosphamide Metabolite $^{15}N$ and $^{17}O$ Phosphoramide Mustards (항암제인 Cyclophosphamide의 중간체인 $^{15}N$$^{17}O$-phosphoramide Mustards의 합성)

  • Koo, Kyo-Im;Ryem, Kon
    • YAKHAK HOEJI
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    • v.38 no.4
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    • pp.455-461
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    • 1994
  • Each nitrogen and oxygen site isotope enriched the cyclophosphamide metabolite phosphoramide mustard was synthesized. Reaction of N,N-bis(2-chloroethyl)phosphoramidic dichloride$[Cl_2P(O)N(CH_2CH_2Cl)_2]$ with benzyl alcohol and ammonia gave N,N-bis(2-chloroethyl)phosphorodiamidic acid phenylmethyl ester $[BzO(H_2N)P(O)N(CH_2CH_2Cl)_2]$. Catalytic hydrogenation of this benzyl ester followed by the addition of cyclohexylamine provided PM. Incorporation of $^{15}NH_3$ into this general scheme gave PM with a $^{15}NH_2$ moiety. Glycine-$^{15}N$ was converted to bis(2-chloroethyl)amine-$^{15}N$ hydrochloride which, in turn, provided for N,N-bis(2-chloroethyl)phosphorodiamidic-$^{15}N$ dichloride. Use of this compound in the general synthetic pathway yielded PM CHA with $^{15}N$ in the mustard moiety. $^{17}O$-Enriched PM was generated through the use of benzyl alcohol-$^{17}O$. To obtain the alcohol, labelled benzaldehyde was made by exchange with $^{17}OH_2$ and was then reduced with sodium borohydride.

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The Study of anti-cancer mechanism with Cobrotoxin on Human prostatic cancer cell line(PC-3) (전립선 암세포에 대한 Cobrotoxin의 항암(抗癌) 기전(機轉) 연구(硏究))

  • Chae, Sang-jin;Song, Ho-seup
    • Journal of Acupuncture Research
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    • v.22 no.3
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    • pp.169-183
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    • 2005
  • Objective : The purpose of this study was to investigate the anti-caner effect of cobrotoxin on the prostatic cancer cell line (PC-3).The goal of study is to ascertain whether cobrotoxin inhibits tile cell growth and cell cycle of PC-3, or the expression of relative genes and whether the regression of PC-3 cell growth is due to cell death or the expression of gene related to apoptosis. Methods : After the treatment of Pc-3 cells with cobrotoxin, we performed 형광현미경, MTT assay, Western blotting, Flow cytometry, PAGE electrophoresis and Surface plasmon resonance analysis to identify the cell viability, cell death, apoptosis, the changes of cell cycle and the related protein, Adk, MAP kinase. Results : 1. Compared with normal cell, the inhibition of cell growth reduced in proportion with the dose of cobrotoxin(0-16nM) in PC-3. 2. Cell viabilities of 0.1, 1, 4nM cobrotoxin treatment were decreased and those of 8, 16nM were decreased significantly. 3. S phase of cell cycle was decreased at the group of 1, 2, 4, 8, 16nM cobrotoxin, but M phase was increased at 0.1, 1, 2, 4, 8, 16nM cobrotoxin. 4. Cox-2 expression after cobrotoxin was peaked at 12hours and was decreased significantly after 6, 12, 24 hours. 5. The expression of Cdk4 was decreased dose-dependently at 1, 2, 4, 8nM cobrotoxin and was decreased siginificantly at 4, 8nM Cyclin D1 was decreased at 1, 2, 4, 8nM and Cycline E was not changed. Cycline B was decreased at 1, 2, 4, 8nM dose-dependently and was decreased siginificanlty at 2, 4, 8nM. 6. The expression of Akt was decreased at 1, 2, 4, 8nM dose-dependently and was decreased significantly at 2, 4, 8nM. 7. ERK was increased at 1, 2nM and decreased at 4, 8nM, p-ERK was increased at 1, 2, 4 nM, but decreased at 8nM. JNK and p-JNK were increased at 1, 4, 8 nM. p38 was increased at 2nM p-p38 was increased at lnM but decreased significantly at 2, 4, 8nM. 8. The nucli of normal cells were stained round and homogenous in DAPI staining, but those of PC-3 were stained condense and splitted. Apoptosis was increased dose-dependently at 2, 4, 8, 16nM and increased significantly at 2, 4, 8, 16nM. 9. Bax wasn`t changed at 1, 2, 4, 8nM and Bcl-2 was decreased significantly at 1, 2, 4, 8nM. Caspase 3 and 9 weren`t changed at 1, 2, 4nM but were decreased significantly at 8nM. Conclusions : These results indicate that cobrotoxin inhibits the growth of prostate Cancer cells, has anti-cancer effects by inducing apoptosis.

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FUNCTIONAL EQUATIONS ASSOCIATED WITH INNER PRODUCT SPACES

  • Park, Choonkil;Huh, Jae Sung;Min, Won June;Nam, Dong Hoon;Roh, Seung Hyeon
    • Journal of the Chungcheong Mathematical Society
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    • v.21 no.4
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    • pp.455-466
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    • 2008
  • In, [7], Th.M. Rassias proved that the norm defined over a real vector space V is induced by an inner product if and only if for a fixed integer $n{\geq}2$ $$n{\left\|{\frac{1}{n}}{\sum\limits_{i=1}^{n}}x_i{\left\|^2+{\sum\limits_{i=1}^{n}}\right\|}{x_i-{\frac{1}{n}}{\sum\limits_{j=1}^{n}x_j}}\right\|^2}={\sum\limits_{i=1}^{n}}{\parallel}x_i{\parallel}^2$$ holds for all $x_1,{\cdots},x_{n}{\in}V$. Let V,W be real vector spaces. It is shown that if a mapping $f:V{\rightarrow}W$ satisfies $$(0.1){\hspace{10}}nf{\left({\frac{1}{n}}{\sum\limits_{i=1}^{n}}x_i \right)}+{\sum\limits_{i=1}^{n}}f{\left({x_i-{\frac{1}{n}}{\sum\limits_{j=1}^{n}}x_i}\right)}\\{\hspace{140}}={\sum\limits_{i=1}^{n}}f(x_i)$$ for all $x_1$, ${\dots}$, $x_{n}{\in}V$ $$(0.2){\hspace{10}}2f\(\frac{x+y}{2}\)+f\(\frac{x-y}{2} \)+f\(\frac{y}{2}-x\)\\{\hspace{185}}=f(x)+f(y)$$ for all $x,y{\in}V$. Furthermore, we prove the generalized Hyers-Ulam stability of the functional equation (0.2) in real Banach spaces.

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Crystal Structures and Characterization of Copper(II) Complexes of N,N,N'N'-Tetrakis(2-pyridylmethyl)-1,2-ethanediamine

  • Yoon, Doo-Cheon;Lee, Uk;Oh, Chang-Eon
    • Bulletin of the Korean Chemical Society
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    • v.25 no.6
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    • pp.796-800
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    • 2004
  • The structure of [Cu(tpen)]$(ClO_4)_2$ (tpen = N,N,N',N'-tetrakis(2-pyridylmethyl)-1,2-ethanediamine) has been identified by X-ray crystallography. The copper(II) ion is surrounded by two amine N atoms and three pyridine N atoms of the ligand, making a distorted trigonal-bipyramid. Among the six potential N donor atoms (two amine N and four pyridine N atoms), only one pyridine N atom remains uncoordinated. We examined structural changes on addition of $Cl^-$ to $[Cu(tpen)]^{2+}$(1). The addition of $Cl^-$ in methanol resulted in the formation of a novel dinuclear copper(II) complex $[Cu_2Cl_2(tpen)](ClO_4)_2{\cdot}H_2O$. The structure of the dinuclear complex was verified by X-ray crystallography. Each copper(II) ion in the dinuclear complex showed a distorted square planar geometry with two pyridine N atoms, one amine N atom and one $Cl^-$ ion.

Hong Gil Ju(洪吉周)'s Algebra (홍길주(洪吉周)의 대수학(代數學))

  • Hong, Sung-Sa;Hong, Young-Hee
    • Journal for History of Mathematics
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    • v.21 no.4
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    • pp.1-10
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    • 2008
  • In this paper, we investigate the part dealing with algebra in Hong Gil Ju's GiHaSinSul to analyze his algebraic structure. The book consists of three parts. In the first part SangChuEokSan, he just renames Die jie hu zheng(疊借互徵) in Shu li jing yun to SangChuEokSan and adds a few examples. In the second part GaeBangMongGu, he obtains the following identities: $$n^2=n(n-1)+n=2S_{n-1}^1+S_n^0;\;n^3=n(n-1)(n+1)+n=6S_{n-1}^2+S_n^0$$; $$n^4=(n-1)n^2(n+1)+n(n-1)+n=12T_{n-1}^2+2S_{n-1}^1+S_n^0$$; $$n^5=2\sum_{k=1}^{n-1}5S_k^1(1+S_k^1)+S_n^0$$ where $S_n^0=n,\;S_n^{m+1}={\sum}_{k=1}^nS_k^m,\;T_n^1={\sum}_{k=1}^nk^2,\;and\;T_n^2={\sum}_{k=1}^nT_k^1$, and then applies these identities to find the nth roots $(2{\leq}n{\leq}5)$. Finally in JabSwoeSuCho, he introduces the quotient ring Z/(9) of the ring Z of integers to solve a system of congruence equations and also establishes a geometric procedure to obtain golden sections from a given one.

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The Age-Related Effect of n-6/n-3 Ratio of Dietary Fats on Lipid Levels and Prostaglandin Production in Rats (식이 다가 불포화 지방산의 n-6/n-3 비율에 의한 흰쥐의 지질수준 및 Prostaglandin 생성에 대한 연령별 비교)

  • 이준호
    • Journal of Nutrition and Health
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    • v.28 no.2
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    • pp.95-106
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    • 1995
  • The effects of various n-6/n-3 ratios(about 2, 4, 6, 8) of dietary fatty acids on various lipid levels and prostaglandin production were studied at the constant P/S ratio (1.5-1.6) in young (5 weeks old) and adult(8 months old) Sprague-Dawley rats using palm oil, safflower oil and sardine oil. The concentration of serum cholesterol tended to increase with the increasing n-6/n-3 ratio. The tendency of HDL-cholesterol levels was similar to serum cholesterol levels. These were not apparent differences between young and adults rats. Serum triglyceride levels increased according to increasing n-6/n-3 ratio in young rats. These were generally high in the adult rats compared with the young rats. Though liver cholesterol level tended to increase according to the increasing n-6/n-3 ratio in the young rats. The liver triglyceride level did not change according to the n-6/n-3 ratio. However, these levels were apparently higher in the adult than in the young rats. The fatty acid compositions of phosphatidylcholine(PC) were similar in serum and liver. The arachidonate/linoleate ratios in tissue PC were influenced by the n-6/n-3 ratio. They tended to be lower in the adult rats compared with the young rats. It was suggested that the activity of $\Delta$6-desturase was decreased by aging. Production of platelet thromboxane A2(TXA2)and aortic prostacyclin(PGI2) was not apparently influenced with n-6/n-3 ratio. Whereas the ratio of TXA2/PGI2 was the lowest value at 3.8 of n-6/n-3 ratio, expecially in the young rats. Thus this ratio seemed to be a desirable level to protect atherosclerosis. These results indicate that the lipid level and prostaglandin production were influenced not only by n-6/n-3 ratio(under constant P/S ratio) but by aging, particulary triglycerde level and arachidonic/linoleic acid ratio.

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A Study on the Preparation of New Functionalized Aminosilanes as a promising coupling agent(I) (결합제로서 가능성 있는 새로운 작용기를 갖는 Aminosilane 제조에 관한 연구(I))

  • 한정식;서태석
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 1998.10a
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    • pp.23-23
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    • 1998
  • Michael Reaction을 이용하여 상업적으로 이용 가능한 APS(3-aminopropyltrime thoxysilane)과 AEAPS(N-[3-(trimethoxysilyl)propy1] ethylenediamine)을 다수의 Michael acceptor(ethyl acrylate, acrylonitrile, acrylamide, 2-cyanoethyl acrylate, 2-hydroxyethyl acrylate 그리고 3-(trimethoxysilyl)propylmethacrylate)와 반응시켜 10종류의 aminosilane ([3-{N-2-carboethoxyethyl)aminopropyl]triethoxysilane, [3-(N-2-cyanoethyl)aminopropyl] triethoxysilane, [3-(N-di-2-carboethoxyethyl) aminopropyl]triethoxysilane, [3-(N-di-2-cyanoethyl)aminopropyl]triethoxysilane, [3-(N-2-cyanoethoxypropionyl)aminopropyl] triethoxysilane, [3-(N-di-2-cyanoethoxypropionyl)aminopropyl] triethoxysilane, [3-(N-di-2-hydroxyethoxypropionyl) aminopropyl]-triethoxysilane, [3-(N-2-amidoethyl aminopropyl]triethoxysilane, {3-[N-(N-di-2-cyanoethyl)ethyl]aminopropyl)triethoxysilane, {3-[N-(3-trimethoxy-silylpropyl)-2-methylpropionyl]aminopropyl)triethoxysilane 등을 35-70% 수율로 제조하였으며, 이들의 구조는 $^1$H-NMR과 FT-IR spectroscopy를 이용하여 확인하였다.

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RECURRENCE RELATIONS FOR QUOTIENT MOMENTS OF THE EXPONENTIAL DISTRIBUTION BY RECORD VALUES

  • LEE, MIN-YOUNG;CHANG, SE-KYUNG
    • Honam Mathematical Journal
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    • v.26 no.4
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    • pp.463-469
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    • 2004
  • In this paper we establish some recurrence relations satisfied by quotient moments of upper record values from the exponential distribution. Let $\{X_n,\;n{\geq}1\}$ be a sequence of independent and identically distributed random variables with a common continuous distribution function F(x) and probability density function(pdf) f(x). Let $Y_n=max\{X_1,\;X_2,\;{\cdots},\;X_n\}$ for $n{\geq}1$. We say $X_j$ is an upper record value of $\{X_n,\;n{\geq}1\}$, if $Y_j>Y_{j-1}$, j > 1. The indices at which the upper record values occur are given by the record times {u(n)}, $n{\geq}1$, where u(n)=min\{j{\mid}j>u(n-1),\;X_j>X_{u(n-1)},\;n{\geq}2\} and u(1) = 1. Suppose $X{\in}Exp(1)$. Then $\Large{E\;\left.{\frac{X^r_{u(m)}}{X^{s+1}_{u(n)}}}\right)=\frac{1}{s}E\;\left.{\frac{X^r_{u(m)}}{X^s_{u(n-1)}}}\right)-\frac{1}{s}E\;\left.{\frac{X^r_{u(m)}}{X^s_{u(n)}}}\right)}$ and $\Large{E\;\left.{\frac{X^{r+1}_{u(m)}}{X^s_{u(n)}}}\right)=\frac{1}{(r+2)}E\;\left.{\frac{X^{r+2}_{u(m)}}{X^s_{u(n-1)}}}\right)-\frac{1}{(r+2)}E\;\left.{\frac{X^{r+2}_{u(m-1)}}{X^s_{u(n-1)}}}\right)}$.

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