• Title/Summary/Keyword: $K_{IC}$

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Screening of Antithrombotic Peptides from Soybean Paste by the Microplate Method (Microplate법에 의한 된장유래의 항혈전 펩타이드 탐색)

  • Shon, Dong-Hwa;Lee, Kyung-Ae;Kim, Seung-Ho;Ahn, Chang-Won;Nam, Hee-Sop;Lee, Hyung-Jae;Shin, Jae-Ik
    • Korean Journal of Food Science and Technology
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    • v.28 no.4
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    • pp.684-688
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    • 1996
  • In order to search for antithrombotic peptides from soybean paste, the inhibitory activity of water extract of soybean paste and its peptide fractions on ADP-induced aggregation of washed platelets was assayed. Soybean paste extract treated with ultrafiltration (M.W. cut off, 3,000 daltons) was found to have inhibitory activity of 90% at the dose of $96\;{\mu}g/ml$ by the method of turbidometric aggregometer. Soybean paste extract was fractionated to 19 fractions (No. B-18) by Dowex 50W X-2 ion exchange column chromatography and activity test was performed by the microplate method. All of the fractions had antithrombotic activity $(IC_{50},\;101,000\;{\mu}g/ml)$, and most fractions had higher activity than positive control, RGDS $(IC_{50}.\;205\;{\mu}g/ml)$. Especially, basic fractions No.16-18 showed higher activity than soybean paste extract $(IC_{50},\;30\;{\mu}g/ml)$. The fraction No.16 with the highest activity $(IC_{50},\;10\;{\mu}g/ml)$ was purified and analysed for amino acid composition. The results showed that histidine, arginine, and alanine were major residues in the peptide part of the fraction.

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Studies on Criterion for Mixed Mode Fracture in Glulam (집성재(集成材)의 혼합모드 하중시 파괴(破壞) 기준(基準)에 관한 연구(硏究))

  • Lee, Jee-Yong;Lee, Jun-Jae
    • Journal of the Korean Wood Science and Technology
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    • v.21 no.2
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    • pp.15-22
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    • 1993
  • This study was carried out to investigate the fracture criterion of glulam. The mixed mode fracture of glulam was investigated by means of single edge notched specimens with various crack inclination in the longitudinal-radial plane. While fracture of wood is not completely understood, the study on linear-elastic fracture mechanics is a rational and valuable tool for studying the strength behavior of glulam. The results are summarized as follows : 1. Glue line has no effect on fracture strength. 2. There is a definite interaction between fracture toughness $K_I$ and $K_{II}$ during the mixed mode fracture of glulam. Several criterions for mixed mode failure were compared. The criterion was expressed in the following form: $(\frac{K_I}{K_{IC}})^2+(\frac{K_{II}}{K_{IIC}})^2=1$ 3. As crack inclination increases, $K_{IC}$ value and $K_{IIC}$ value decreases. The equations relating crack angle to $K_{IC}$ and $K_{IIC}$, respectively, were obtained as follows; $K_{IC}$ = -77.42${\gamma}$+153.72 ($R^2$ = 0.78) $K_{IIC}$ = -9.17${\gamma}$+34.90 ($R^2$ = 0.48)

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Design and Implementation of Optical Receiving Bipolar ICs for Optical Links

  • Nam Sang Yep;Ohm Woo Young;Lee Won Seok;Yi Sang Yeou1
    • Proceedings of the IEEK Conference
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    • 2004.08c
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    • pp.717-722
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    • 2004
  • A design was done, and all characteristic of photodetectr of the web pattern type which a standard process of the Bipolar which Si PIN structure was used in this paper, and was used for the current amplifier design was used, and high-speed, was used as receiving optcal area of high altitude, and the module which had a low dark current characteristic was implemented with one chip with a base. Important area decreases an area of Ie at the time of this in order to consider an electrical characteristic and economy than the existing receiving IC, and performance of a product and confidence are got done in incense. First of all, the receiving IC which a spec, pattern of a wafer to he satisfied with the following electrical optical characteristic that produced receiving IC of 5V and structure are determined, and did one-chip is made. On the other hand, the time when AR layer of double is $Si_{3}N_{4}/SiO_{2}=1500/1800$ has an optical reflectivity of less than $10{\%}$ on an incidence optical wavelength of 660 ,and, in case of photo detector which reverse voltage made with 1.8V runs in 1.65V, an error about a change of thickness is very the thickness that can be improved surely. And, as for the optical current characteristic, about 5 times increases had the optical current with 274nA in 55nA when Pc was -27dBm. A BJT process is used, and receiving IC running electricity suitable for low voltage and an optical characteristic in minimum 1.8V with a base with two phases is made with one chip. IC of low voltage operates in 1.8V and 3.0V at the same time, and optical link receiving IC is going to be implemented

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Analysis of Elementary School Teachers' Innovation Configuration on STEAM (융합인재교육(STEAM)에 대한 초등학교 교사의 실행 형태 분석)

  • Chae, Hee In;Noh, Suk Goo
    • Journal of Science Education
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    • v.39 no.1
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    • pp.44-57
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    • 2015
  • The purpose of this study was to analyze the teachers' Innovation Configuration(IC) on STEAM of the 2009 elementary science curriculum and to implicate the assessment of STEAM. Therefore, this study was conducted by the IC component checklist of the Concerns-Based Adoption Model(CBAM). The total number of 126 teachers participated in this study. The results of the study were as follows: First, time management(33.3%) was the most ideal IC. On the other hand, curriculum planning(34.1%) was the most unacceptable IC. Second, the results of the chi-square test showed that the IC were significantly different according to their positions, career in education and training experiences(p<.05). Third, to explore the teacher's epistemic beliefs on STEAM, one in-service elementary teacher who studied in a doctoral course of a graduate school of education participated in the study. Based on these results, we suggested that the support of application and the revolution of the science curriculum and assessment should be implemented according to the teachers' IC.

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Comparison of on rat intestinal ${\alpha}-glucosidase$ activity and the chemical compositions of Korean and Chinese Schizandra chinensis

  • Chae, Hee-Jun;Lee, Min-Hu;Kim, Sun-Hyo;Moon, Hae-Yeon
    • 한국생물공학회:학술대회논문집
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    • 2005.04a
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    • pp.546-552
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    • 2005
  • The purpose of this study was to determine the effect of rat intestinal ${\alpha}-glucosidase$ inhibitor ; methanol(80%), ethanol(80%) and $dH_2O$ extract of Schizandra chinensis in Korea(KS : Schizandra chinensis in Korea) and China(CS : Schizandra chinensis in China). When the final concentration was 1 $mg/m{\ell}$ for each sample(KS and CS), MeOH extract of KS($IC_{50}$ 1.62 mg/ml) showed 46.8%, EtOH extract of KS($IC_{50}$ 1.48 mg/ml) showed 47.4%, $dH_2O$ extract of KS($IC_{50}$ 1.72 mg/ml) showed 46.3% and MeOH extract of CS($IC_{50}$ 8.35 mg/ml) showed 13.3%, EtOH extract of CS($IC_{50}$ 8.05 mg/ml) showed 16%, $dH_2O$ extract of CS($IC_{50}$ 8.37 mg/ml) showed 11.54% of inhibiter for p-nitrophenyl ${\alpha}$, D-glucopyranoside ${\alpha}-glcosidase$ activity, respectively, And the contents of total phenol, flavonoid of Schizandra chinensis were measured. When the final concentration was 1 $mg/m{\ell}$ for each sample(KS and CS), total phenol and flavonoid in KS were higher than CS, respectively.

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Analysis of Rainfall-Runoff Characteristics on Impervious Cover Changes using SWMM in an Urbanized Watershed (SWMM을 이용한 도시화유역 불투수율 변화에 따른 강우유출특성 분석)

  • Oh, Dong Geun;Chung, Se Woong;Ryu, In Gu;Kang, Moon Seong
    • Journal of Korean Society on Water Environment
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    • v.26 no.1
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    • pp.61-70
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    • 2010
  • The increase of impervious cover (IC) in a watershed is known as an important factor causing alteration of water cycle, deterioration of water quality and biological communities of urban streams. The study objective was to assess the impact of IC changes on the surface runoff characteristics of Kap Stream basin located in Geum river basin (Korea) using the Storm Water Management Model (SWMM). SWMM was calibrated and verified using the flow data observed at outlet of the watershed with 8 days interval in 2007 and 2008. According to the analysis of Landsat satellite imagery data every 5 years from 1975 to 2000, the IC of the watershed has linearly increased from 4.9% to 10.5% during last 25 years. The validated model was applied to simulate the runoff flow rates from the watershed with different IC rates every five years using the climate forcing data of 2007 and 2008. The simulation results indicated that the increase of IC area in the watershed has resulted in the increase of peak runoff and reduction of travel time during flood events. The flood flow ($Q_{95}$) and normal flow ($Q_{180}$) rates of Kap Stream increased with the IC rate. However, the low flow ($Q_{275}$) and drought flow ($Q_{355}$) rates showed no significant difference. Thus the subsurface flow simulation algorithm of the model needs to be revisited for better assessment of the impact of impervious cover on the long-term runoff process.

The Effect of Mobile Phase and Dissolving Solvent on the Enantiomer Separation Using a Covalently Immobilized Chiral Column Derived from Polysaccharide Derivative (다당유도체로 공유결합된 카이랄 칼럼에서 이동상과 분석물질의 용매가 거울상 이성질체의 광학분할에 미치는 영향)

  • Huang, Hu;Lee, Beom-Gyu;Baek, Chae-Sun;Lee, Won-Jae
    • Journal of the Korean Chemical Society
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    • v.53 no.2
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    • pp.137-143
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    • 2009
  • Liquid chromatographic enantiomer separation of N-tert-butoxycarbonyl (BOC) $\alpha$-amino acids and their ethyl esters was performed on covalently immobilized chiral column (Chiralpak IC) derived from polysaccharide derivative. The solvent versatility of the covalently immobilized Chiralpak IC in enantiomer separation of N-BOC $\alpha$-amino acid ethyl ester derivatives was shown and the chromatographic parameters of their enantioselectivities and resolution factors were greatly influenced by the nature of the mobile phase. Also the effect on the dissolving solvent for these analytes on the enantiomer separation using the same mobile phase and the examples of preparative enantiomer separation on analytical column were shown.

Optimization of Power Bumps and TSVs with Optimized Power Mesh Structure for Power Delivery Network in 3D-ICs (3D-IC 전력 공급 네트워크를 위한 최적의 전력 메시 구조를 사용한 전력 범프와 TSV 최소화)

  • Ahn, Byung-Gyu;Kim, Jae-Hwan;Jang, Cheol-Jon;Chong, Jong-Wha
    • Journal of IKEEE
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    • v.16 no.2
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    • pp.102-108
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    • 2012
  • 3-dimensional integrated circuits (3D-ICs) have some problems for power delivery network design due to larger supply currents and larger power delivery paths compared to 2D-IC. The power delivery network consists of power bumps & through-silicon-vias (TSVs), and IR-drop at each node varies with the number and location of power bumps & TSVs. It is important to optimize the power bumps & TSVs while IR-drop constraint is satisfied in order to operate chip ordinarily. In this paper, the power bumps & TSVs optimization with optimized power mesh structure for power delivery network in 3D-ICs is proposed.

Study of thermal stability of Nitrogen doped Nickel Germanosilicide (Nitrogen 도핑된 Nickel Germanosilicide의 열안정성 연구)

  • Oh Soon-Young;Yun Jang-Gn;Hwang Bin-Feng;Kim Yong-Jin;Ji Hee-Hwan;Kim Ui-Sik;Cha Han-Seob;Heo Sang-Bum;Lee Jeong-Gun;Wang Jin-Suk;Lee Hi-Deok
    • Proceedings of the IEEK Conference
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    • 2004.06b
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    • pp.513-516
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    • 2004
  • 본 논문에서는 $20\%$ Ge 조성 비율을 갖는 SiGe 200nm 에 $1\%$-Nitrogen doping 된 Nickel 을 이용하여 새로운 Nickel Germanosilicide 방법을 제안하여 Ni-Germanosilicide 의 단점인 열 안정성 개선에 대해 연구하였다. Nitrogen atom 이 grain boundary 에 존재하여 Nickel의 diffusion을 억제시키는 역할을 하여 shallow한 실리사이드와 uniform 한 실리사이드 계면 특성을 얻게 되었다. 그리고 실리사이드 형성 후, 고온로 열처리 $600^{\circ}C$, 30min 후에도 낮고 안정한 면 저항 특성으로 열안정성 개선 할 수 있다.

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Electrical Characteristics of Power Switching Sensor IC fabricated in Bipolar-CMOS-DMOS Process (BCD 프로세스를 이용한 파워 스위칭 센서 IC의 제작과 특성 연구)

  • Kim, Sunjung
    • Journal of IKEEE
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    • v.20 no.4
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    • pp.428-431
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    • 2016
  • Power semiconductor devices had been producted with bipolar only processes, but Bipolar-CMOS-DMOS(BCD) processes have been adapted recently to fabricate these devices since most foundry companies have provided BCD processes instead of Bipolar only processes. In this study, Regulator and OP Amp are used as most popular design IPs and BCD processes for the designing are converted from bipolar only processes. Power Switching Sensor(PSS) ICs are designed specifically and fabricated on a silicon chip. The operation results of the packaged chip show the good matching with test results of the simulation.